Comparing Amantadine vs Modafinil
Amantadine Remove Amantadine from your drug comparison | Modafinil Remove Modafinil from your drug comparison |
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Amantadine Remove Amantadine from your drug comparison | Modafinil Remove Modafinil from your drug comparison | ||||||||||||||||
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Prescribed for Extrapyramidal Reaction, Parkinson's Disease, Influenza, Influenza A. May also be prescribed off label for Chronic Fatigue Syndrome, ADHD, Fatigue, Head Injury, Influenza Prophylaxis,... View more |
Prescribed for Shift Work Sleep Disorder, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome. May also be prescribed off label for ADHD, Chronic Fatigue Syndrome, Depression, Drowsiness, Fatigue. |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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7.1
For Parkinson's Disease: Works to stop Dyskinesia caused by senement/dopamine pills |
7.4
For Depression: For me it's impressive! After my Burnout and the following depression, it was a struggle for me, that I wasn't able to bring the past performance. Lack of energy and concentration, mood swings, bad memory, and so on. With Modafinil I am able to work focused on my dream, fight procrastination (which was a real problem), think-power from past days (I often gave up when I had so solve something complex) I don't take it every day, sometimes only 1-2 days a week. Mostly when I'm working on my project or when I feel really bad. Side Effects: Headache during effect-phase (when I started, but was gone after the third intake) Insomnia (when you take it too late) For Depression: I have struggled with major depression since I was 13 (I'm 23 now). I have been put trough the ringer of all the traditional antidepressant classes. I've tried two SSRI's, three SNRI's, several different atypical antipsychotics, Remeron, Lamictal, and Wellbutrin XL. I'm a man and have had terrible sexual side effects with antidepressants. Recently I was diagnosed with treatment resistant depression, and I said I need something new. My psychiatrist suggested Provigil, since it is less likely than other stimulants to worsen high blood pressure. It has been a godsend for my depression. I have energy, intense focus and have been doing much better in my college courses. Long work shifts that used to drag on forever now seem to fly by. I am more patient and outgoing than I have ever been. Now I just take this and Wellbutrin XL. Definitely recommend. Should be used much more frequently for refractory depression. It's not covered on insurance but I can get it for like $40 per month. |
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Drug Class |
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Side Effects |
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See the full amantadine side effects document. |
Commonly reported side effects include: headache, and nausea. See the full modafinil side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all amantadine prices |
View all modafinil prices |
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Generic Availability |
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Yes (this medicine) |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Gocovri, Osmolex ER | Provigil | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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19 hours |
15 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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FDA Alerts |
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Drug Interactions |
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A total of 124 drugs are known to interact with amantadine:
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A total of 416 drugs are known to interact with modafinil:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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February 14, 1968 |
December 24, 1998 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Parkinson's Disease: Started Amantadine 4 weeks ago 200 mg per day. Noticed immediately occasional dizziness and diarrhea after every 100mg capsule, lost any desire to get up and do anything, Midway through the third week, I cut my dosage down to 100 mg capsule per day, taken every evening at 8 pm before bedtime and that helped me sleep better and as well increased movement in arms and right leg and foot. Happy to say I am very pleased with the results!