Comparing Amantadine vs Modafinil
Amantadine | Modafinil |
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Amantadine | Modafinil |
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Prescription only
Amantadine may be used to treat dyskinesia or reduce the number of OFF episodes in those with Parkinson's disease (PD) OR in the treatment or prevention of Influenza A viral infection. Nausea... View more |
Prescription only
Prescribed for Chronic Fatigue Syndrome, ADHD, Fatigue, Depression, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, Shift Work Sleep Disorder, Idiopathic Hypersomnia. Modafinil may also be... View more |
Related suggestions ADHD (Attention Deficit Hyperactivity Disorder)
Chronic Fatigue Syndrome
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More about Amantadine | More about Modafinil | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Amantadine has an average rating of 6.9 out of 10 from a total of 54 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 20% reported a negative effect. |
Modafinil has an average rating of 7.3 out of 10 from a total of 536 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 18% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Amantadine side effects |
View all Modafinil side effects |
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Drug Class | |||||||||||||||||
Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Amantadine prices |
View all Modafinil prices |
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Dosage Forms | |||||||||||||||||
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Brand Names | |||||||||||||||||
Gocovri, Osmolex ER | Provigil | ||||||||||||||||
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
19 hours |
15 hours |
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CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 131 drugs are known to interact with Amantadine:
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A total of 521 drugs are known to interact with Modafinil:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
February 14, 1968 |
December 24, 1998 |
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WADA Class View classifications | |||||||||||||||||
N/A |
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More Information | |||||||||||||||||
Patient Resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.