Comparing Amantadine vs Modafinil
| Amantadine | Modafinil |
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| Amantadine | Modafinil |
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Prescription only
Amantadine may be used to treat dyskinesia or reduce the number of OFF episodes in those with Parkinson's disease (PD) OR in the treatment or prevention of Influenza A viral infection. Nausea... View more |
Prescription only
Prescribed for Chronic Fatigue Syndrome, ADHD, Depression, Fatigue, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, Shift Work Sleep Disorder, Idiopathic Hypersomnia. Modafinil may also be... View more |
Related suggestions ADHD (Attention Deficit Hyperactivity Disorder)
Chronic Fatigue Syndrome
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| More about Amantadine | More about Modafinil | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Amantadine has an average rating of 7.0 out of 10 from a total of 55 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 20% reported a negative effect. |
Modafinil has an average rating of 7.3 out of 10 from a total of 536 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Amantadine side effects |
View all Modafinil side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Amantadine prices |
View all Modafinil prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Gocovri, Osmolex ER | Provigil | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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19 hours |
15 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 131 drugs are known to interact with Amantadine:
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A total of 521 drugs are known to interact with Modafinil:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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February 14, 1968 |
December 24, 1998 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Benadryl Allergy
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Artane
Artane is used for cerebral spasticity, extrapyramidal reaction, parkinson's disease
Gocovri
Gocovri (amantadine) is used in the treatment of Parkinson's disease. Includes Gocovri side ...
Trihexyphenidyl
Trihexyphenidyl is used for cerebral spasticity, extrapyramidal reaction, parkinson's disease
Benztropine
Benztropine is used for extrapyramidal reaction, hyperhidrosis, parkinson's disease
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.