Comparing Alprazolam vs Buprenorphine / Naloxone
| Alprazolam | Buprenorphine / naloxone |
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| Alprazolam | Buprenorphine / naloxone |
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Prescription only
Alprazolam is used for the acute treatment of generalized anxiety disorder (GAD) and panic disorder (PD) in adults. Carries boxed warnings for opioid interactions, abuse/addiction, and... View more |
Prescription only
Buprenorphine/naloxone combines an opioid with an antagonist to treat opioid dependence by suppressing withdrawal symptoms. Used as maintenance therapy alongside counseling, it's given once daily... View more |
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| More about Alprazolam | More about Buprenorphine / naloxone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Alprazolam has an average rating of 8.6 out of 10 from a total of 1503 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 8% reported a negative effect. |
Buprenorphine / naloxone has an average rating of 7.7 out of 10 from a total of 1135 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Alprazolam side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Alprazolam prices |
View all Buprenorphine / naloxone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Alprazolam Intensol, Xanax, Xanax XR | Suboxone, Zubsolv | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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20 hours |
37 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 565 drugs are known to interact with Alprazolam:
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A total of 734 drugs are known to interact with Buprenorphine / naloxone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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October 16, 1981 |
October 08, 2002 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.