Comparing Adapalene Topical vs Spironolactone
Adapalene topical | Spironolactone |
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Adapalene topical | Spironolactone |
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Prescription and OTC
Prescribed for Acne. Adapalene topical may also be used for purposes not listed in this medication guide. |
Prescription only
Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more |
Related suggestions |
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More about Adapalene topical | More about Spironolactone | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Adapalene topical has an average rating of 6.3 out of 10 from a total of 519 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 32% reported a negative effect. |
Spironolactone has an average rating of 6.8 out of 10 from a total of 705 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 25% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Adapalene topical side effects |
View all Spironolactone side effects |
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Drug Class | |||||||||||||||||
Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Adapalene topical prices |
View all Spironolactone prices |
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Dosage Forms | |||||||||||||||||
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Brand Names | |||||||||||||||||
Differin, Plixda | Aldactone, CaroSpir | ||||||||||||||||
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
51 hours |
37 hours |
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CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 12 drugs are known to interact with Adapalene topical:
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A total of 382 drugs are known to interact with Spironolactone:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
May 31, 1996 |
January 21, 1960 |
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WADA Class View classifications | |||||||||||||||||
N/A |
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More Information | |||||||||||||||||
Patient Resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.