Comparing Acetaminophen / Hydrocodone vs Nucynta
| Acetaminophen / hydrocodone | Nucynta (tapentadol) |
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| Acetaminophen / hydrocodone | Nucynta (tapentadol) |
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Prescription only
Acetaminophen/hydrocodone may be used to treat moderate-to-severe pain that is unrelieved by nonopioid analgesics. However, its use is limited by the dependence and addiction potential of the... View more |
Prescription only
Prescribed for Pain. Nucynta may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Acetaminophen / hydrocodone | More about Nucynta (tapentadol) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Acetaminophen / hydrocodone has an average rating of 6.0 out of 10 from a total of 1316 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 35% reported a negative effect. |
Nucynta has an average rating of 6.3 out of 10 from a total of 279 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 28% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Nucynta side effects |
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| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Acetaminophen / hydrocodone prices |
View all Nucynta prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Xodol, Zyfrel | Other tapentadol brands include: Nucynta ER | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.8 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 683 drugs are known to interact with Acetaminophen / hydrocodone:
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A total of 399 drugs are known to interact with Nucynta:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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May 03, 1982 |
November 20, 2008 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.