Comparing Acetaminophen / Hydrocodone vs Nucynta
| Acetaminophen / hydrocodone | Nucynta (tapentadol) |
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| Acetaminophen / hydrocodone | Nucynta (tapentadol) |
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Prescription only
Acetaminophen/hydrocodone may be used to treat moderate-to-severe pain that is unrelieved by nonopioid analgesics. However, its use is limited by the dependence and addiction potential of the... View more |
Prescription only
Prescribed for Pain. Nucynta may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Acetaminophen / hydrocodone | More about Nucynta (tapentadol) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Acetaminophen / hydrocodone has an average rating of 6.0 out of 10 from a total of 1315 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 35% reported a negative effect. |
Nucynta has an average rating of 6.3 out of 10 from a total of 279 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 28% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Nucynta side effects |
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| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Acetaminophen / hydrocodone prices |
View all Nucynta prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Xodol, Zyfrel | Other tapentadol brands include: Nucynta ER | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.8 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 682 drugs are known to interact with Acetaminophen / hydrocodone:
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A total of 398 drugs are known to interact with Nucynta:
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| First Approval Date | |||||||||||||||||
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May 03, 1982 |
November 20, 2008 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.