Skip to main content

Zoledronic acid User Reviews & Ratings (Page 5)

Brand names: Reclast, Zometa, Aclasta

Zoledronic acid has an average rating of 4.8 out of 10 from a total of 396 reviews on Drugs.com. 35% of reviewers reported a positive experience, while 47% reported a negative experience.

Reviews for Zoledronic acid

  • whata...
  • Taken for less than 1 month
  • September 2, 2020

Reclast (zoledronic acid) for Osteoporosis "Female, 78 years young! First Reclast infusion in July 2020, no one told me to drink extra water prior to infusion. While still at the center, I started getting a bad stomach ache, which lasted 3 days. It was BAD, the first 18 hours unbearable - Dexa score 2018 -2.5, 2019 -2.9, July -3.2 - I've taken 1,200 Calc with D3 for years, also Magnesium daily, eat well, osteoarthritis and porosis in feet really bad, fingers and hips - feeling fine now, no other side effects noted."

Was this helpful?YesNo
48 Report
  • AMA
  • Taken for 6 months to 1 year
  • January 1, 2020

Reclast (zoledronic acid) for Osteoporosis "I had the Reclast infusion back in March 2019. I have experienced more bone pain than I did prior to the infusion. Still in pain. The day after I had the infusion I had to go to the ER due to higher than normal blood pressure. 196/102. A headache, etc. Is this normal to still be in pain and fatigued?"

Was this helpful?YesNo
54 Report
  • sunsh...
  • Taken for 1 to 6 months
  • September 15, 2016

Reclast (zoledronic acid) for Osteoporosis "Received dose at 11am, by 10pm that night I had fever, chills, severe pain in back. I was extremely ill for 3 days, such a severe headache I couldn't open my eyes. A week later my hands suddenly swelled to the point I could not use them. Now nearly 3 months later I am in physical therapy to try to regain the strength in my legs. Other side effects were less severe, such as jaw pain for a few weeks. I would never ever take this medicine again."

1 / 10
Was this helpful?YesNo
80 Report

Frequently asked questions

  • Annie
  • Taken for less than 1 month
  • January 27, 2020

Reclast (zoledronic acid) for Prevention of Osteoporosis "I received a Reclast infusion on December 26, 2019, for osteopenia. The next night, I awoke with a terrible headache and was unable to ignore it. I took a pain reliever and slept for 4 hours only to awaken again in severe head pain. The next day, I still felt truly horrible. I went to the ER because it was a Saturday, where I had an X-ray of my neck, and the ER doctor gave me 4 trigger point injections of lidocaine in the base of my skull. Still fighting pain! Additional trigger point injections. When does it end? A month so far of pain. Don’t do it!!"

1 / 10
Was this helpful?YesNo
53 Report
  • Suz
  • Taken for 1 to 6 months
  • May 7, 2019

Reclast (zoledronic acid) for Osteoporosis "I had the Reclast infusion on April 4th, and 12 hours later I had severe chills (shaking so bad I couldn't close my mouth to take my temp) and fever. Lasted for 6 hours. Then I was sick to my stomach for the next day with severe pain in my legs (hard to get up from a chair) and my hands (hurt to write). Then I started with a 'cold' sinus/bronchial infection, which sent me to urgent care for an inhaler and cough medicine. Back to the doctor after 5 days for antibiotics, and I'm still sick one month later. Now jaw pain on the left side, and my teeth hurt. I will NEVER take Reclast EVER again. I hope you won't either!!!"

1 / 10
Was this helpful?YesNo
59 Report

Are you taking this medicine?

  • PAW
  • Taken for less than 1 month
  • December 9, 2019

Aclasta (zoledronic acid) for Osteoporosis "I had Aclasta on the 21st of November 2019. No side effects for about a week. Now, every day I wake up with side effects of bone pain and muscle pain. Sometimes my feet are very sore. Hope all this stops soon. I will not be having any more Aclasta."

4 / 10
Was this helpful?YesNo
54 Report
  • Melissa
  • July 26, 2020

Reclast (zoledronic acid) for Prevention of Osteoporosis "Just had my first Reclast infusion on July 23, 2020. Just getting out of bed for the first time in 3 days. I have side effects of the worst pain ever in my bones and my head, hands, back! I felt like every bone in my body was punched, kicked, and crushed. I could feel each bone ache individually (if that makes sense). Headache was so bad I got sick. However, day 3 is the magic number, and I am feeling much better ;). It has been very bad, but I have made it through with lots of rest, laying in bed watching movies. I think for me it was worse than chemo, yuck feeling. *** Don’t know how effective until next year."

Was this helpful?YesNo
48 Report
  • Blond...
  • May 22, 2020

Zometa (zoledronic acid) for Osteoporosis "I will never try Zometa again. I had horrific side effects. I passed out 7 hours after home from infusion, my neighbor called paramedics. My blood pressure dropped to 80/58. I’ve had full body ache, headache, sweats, and chills for 3 days so far."

1 / 10
Was this helpful?YesNo
48 Report
  • FatCh...
  • Taken for less than 1 month
  • October 30, 2014

Reclast (zoledronic acid) for Osteoporosis "Had my infusion yesterday. I drank a few glasses of water in the morning and took an ibuprofen during the treatment. I had expected the '3 days of flu-like symptoms' and even scheduled sick time to be prepared. Zero side-effects, no aches or pains, nothing...but still taking the time off so I can have fun. My stats: 50, 100#, just finished 2 years of Forteo, I take 1200mg Calcium a day plus an Rx Vitamin D each month."

6 / 10
Was this helpful?YesNo
88 Report
  • Henry
  • Taken for less than 1 month
  • September 2, 2019

Reclast (zoledronic acid) for Osteoporosis "After being reassured by 2 physicians, one an MD, another oncologist: that this option for infusion would offset any negative side effects for the benefit I would receive. Couldn't have been more untrue in my case. After infusion, bedridden for 3 days with limited movement due to extremely painful joints. Been 8 days now, and I'm just now getting back on my feet but weak. Please get multiple opinions from all before considering this medication. Never again."

1 / 10
Was this helpful?YesNo
53 Report
  • CJano
  • Taken for 6 months to 1 year
  • May 1, 2021

Reclast (zoledronic acid) for Osteoporosis "I have been in pain for over 6 months after Reclast. Picking up a tiny cup of water sends pain to my back. I am okay if resting. Pain in all joints and bones. I am 82. Never a bit of pain prior to this infusion. I have never fallen as an adult. I was never told by my doctor to drink water a day prior. I would like to join a lawsuit if there is one."

1 / 10
Was this helpful?YesNo
39 Report
  • Mano
  • July 17, 2020

Reclast (zoledronic acid) for Osteoporosis "55-year-old with osteoporosis (genetic predisposition as well as early menopause). Had my first infusion yesterday. Did prep with lots of water and Tylenol (hence up peeing throughout the night). Today I am sore, stiff, have a headache, and fatigued. But all manageable with Tylenol and Advil (taken 2 hours apart). Deep breaths hurt and took an almost 3-hour nap today (at least during the pandemic I don’t have to work)."

Was this helpful?YesNo
45 Report
  • Recast...
  • May 7, 2017

Reclast (zoledronic acid) for Osteoporosis "Had the infusion twice. The only side effect the first time was a slight headache. The second time, no side effects at all. I highly recommend having this. Make sure you are well-hydrated the day of the procedure."

10 / 10
Was this helpful?YesNo
69 Report
  • Phyli...
  • Taken for less than 1 month
  • March 17, 2014

Reclast (zoledronic acid) for Osteoporosis "I had my infusion on Friday. My doctor gave me Tylenol at that time and said take one twice a day for 3 days. On Sunday, I woke up with some leg muscle pain. I took 2 Tylenol and an Aleve later on in the morning. Felt fine all day and I resumed my gym workouts on Monday. This was a breeze."

10 / 10
Was this helpful?YesNo
89 Report
  • Connie...
  • Taken for less than 1 month
  • February 7, 2020

Reclast (zoledronic acid) for Osteoporosis "Feb 7th update. I did my original post on Jan 30 under the same name, about having the Reclast infusion on Jan. 27, 2020. Just so you know how long the side effects for Reclast last, I am still having pain in my legs, blurred vision, some nausea, and headache, but able to get up and down the stairs now, eating a little bit better. Starting to feel a little better."

4 / 10
Was this helpful?YesNo
48 Report
  • Pat...
  • Taken for 2 to 5 years
  • January 21, 2024

Reclast (zoledronic acid) for Osteoporosis "I had my 2nd Reclast infusion a week ago. Drank plenty of water before and after. Took precautionary acetaminophen for two days after. No side effects whatsoever. There was an improvement in bone density after 1st time (3 years ago)."

10 / 10
Was this helpful?YesNo
11 Report
  • Connie...
  • January 30, 2020

Reclast (zoledronic acid) for Osteoporosis "Had my infusion on Monday, Jan. 27, 2020. Was just tired and weak at first, then in the middle of the night, I had the most excruciating pain in my bones all night until morning. Doctor then gave me tramadol, which helped the pain, but the next day I vomited all day long. It’s been 4 days, and I’m nauseous, my head still hurts, have no strength to get out of bed or eat much."

Was this helpful?YesNo
47 Report
  • Arose
  • Taken for less than 1 month
  • May 22, 2022

Reclast (zoledronic acid) for Prevention of Osteoporosis "It’s been a little over 48 hours since my 15-minute Reclast infusion. It was easy. No side effects in the first 24 hours, then some pain in my hip area. I took ibuprofen, and it went away in about an hour. Woke up the next morning with a sore throat and a little more pain in my hip, but took ibuprofen again, it did the trick. This was my first infusion. If I get a good outcome, I’ll definitely do it again."

10 / 10
Was this helpful?YesNo
28 Report
  • SueBu...
  • Taken for 2 to 5 years
  • June 5, 2013

Zometa (zoledronic acid) for Osteolytic Bone Metastases of Solid Tumors "I have been receiving Zometa via IV infusion for about 3 years now. At first, three weekly, then after about a year, four weekly. I have breast cancer and bone metastasis. If I take the infusion over 15 minutes, during the following day I will begin with severe vomiting and flu symptoms, which last for two days and nights, after which I'm fine. However, if I have the infusion over 30 minutes - as advised on the internet way back in the early days of my treatments - I have NO side effects whatsoever, no sickness, no aches, and pains! I have spoken to other women who have experienced the same - take the infusion slower, drink plenty of water, and you might just find your horrid side effects disappear!"

Was this helpful?YesNo
91 Report
  • Laura
  • Taken for less than 1 month
  • July 31, 2022

Reclast (zoledronic acid) for Prevention of Osteoporosis "I had my first infusion of Reclast on a Wednesday afternoon. By 3 AM Thursday morning I had fever, chills and extreme body aches. Nauseated and a headache. Pretty extreme, took Tylenol got a little relief. The next 24-48 hrs. has been pretty terrible, still slowly recovering. Will not do this infusion ever again. I was told by the nurses well you might feel a little achy that wasn’t even close to how bad I felt."

2 / 10
Was this helpful?YesNo
26 Report
  • Jaclash
  • Taken for less than 1 month
  • June 16, 2017

Zometa (zoledronic acid) for Osteolytic Bone Metastases of Solid Tumors "Had my first dose on Monday, 12th June 2017. I was fine Monday night, so I felt quite positive. Woke up Tuesday feeling like death! Wednesday, I felt better but had a painful, red, swollen left eyeball. Long story short, I'm in agony with my eye, and no one knows what to do! The hospital tried to say it wasn't a side effect! It's a very rare side effect, but it is one! And the fact they know nothing about it or how to deal with it is disgusting and frightening! I will not be having this treatment again and will be taking this further! They should not be giving people something if they don't know everything about it!"

Was this helpful?YesNo
64 Report
  • Avara
  • Taken for 2 to 5 years
  • November 13, 2016

Aclasta (zoledronic acid) for Osteoporosis "I have Osteogenesis Imperfecta. After getting Aredia for years and not seeing much improvement (maybe it prevented deterioration), I received Aclasta for 2 years and my bone density went from very fragile to just below average. That was 2 years ago. No side effects and no deterioration as of yet. I'm very happy to be repaired."

10 / 10
Was this helpful?YesNo
68 Report
  • Bammy
  • Taken for less than 1 month
  • November 19, 2019

Reclast (zoledronic acid) for Osteoporosis "Had my first infusion Nov 15, 2019. I started getting the flu-like symptoms about 8 hours later. Thought it was the end of me. I shook for 2 days with chills. Couldn’t pick my arm up to get the Tylenol off my nightstand. 5 hours later, I finally got them and every blanket I owned. It hurt so much. Then started with throwing up and diarrhea. It’s been 4 days, and I’m still in bed, beyond tired. Not sure how to rate the medicine because it hasn’t started to work yet. But the side effects are really bad. Make sure you have lots of water, Gatorade, and Tylenol or pain meds, you’ll need them."

6 / 10
Was this helpful?YesNo
47 Report
  • mcm
  • Taken for 6 months to 1 year
  • February 25, 2023

Reclast (zoledronic acid) for Osteoporosis "Follow up on initial reclast first taken 3/ 2022. I was never informed of any prep to do beforehand, I suffered violent severe side effects for 8 days immediately after the reclast infusion I was so ill I was unable to call 911 and get myself to a hospital. I was completely incapacitated with severe bone pain, rolling head-to-toe cramps, extreme flu-like symptoms, chills, fevers, and a blinding headache that lasted for 8 days. Now one year after I am still experiencing severe and extreme bone pain that many times causes me to be unable to lift my arms and has impacted my quality of life. Additionally, I suffered another compression fracture with zero exertion in June of 2022. I also require several implants and refuse to potentially destroy my jaw. Reclast side effects outweigh any possible benefits. I will be 57 yrs old this year, and prior to 2022 had no knowledge I had osteoporosis. I pray I have no further issues!"

1 / 10
Was this helpful?YesNo
20 Report
  • AvoidAt...
  • Taken for less than 1 month
  • April 26, 2023

Reclast (zoledronic acid) for Prevention of Osteoporosis "I had the infusion early Friday afternoon. Within 3 hours, I had a very intense headache. By midnight, the headache was unbearable, and I also experienced deep pain, chills, dizziness, and chest pain that felt like a cement block between the ribs. On Saturday, all these issues persisted, along with a fever. On Sunday, I still had the same symptoms and also developed numbness in my legs, feet, arms, and hands. I also noticed loads of small, tiny spots on my palms and fingers. On Monday and Tuesday, the symptoms persisted, and I was unable to get out of bed. Concerned about all these issues, I called my doctor, who prescribed a 6-day cycle of steroids to try to flush out the medication. While I am aware that no one can predict how a body will react to any medication, simply saying that you may feel flu-like symptoms understates what I have been going through. I have never regretted a medical decision more than this one! Please research and know that this has caused havoc on my body, and who knows if I'll ever be the same again."

1 / 10
Was this helpful?YesNo
18 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.