Skip to Content

User Reviews for Effexor XR

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Filter by:

Effexor XR Rating Summary

User Ratings
10
   
25%(14)
9
   
16%(9)
8
   
25%(14)
7
   
4%(2)
6
   
2%(1)
5
   
8%(4)
4
   
6%(3)
3
   
6%(3)
2
   
2%(1)
1
   
11%(6)
7.1/10 Average Rating
57 Ratings with 54 User Reviews

What next? Compare all 61 medications used in the treatment of Major Depressive Disorder.

Reviews for Effexor XR to treat Major Depressive Disorder

Sort by:

"I'm on the Effexor 50mg dose. You can get a bead form or a tablet form. Well when I'm on the bead form it acts like I haven't taken it at all - I get dizzy, feel sick, often vomit but when I'm on the tablet form I'm fine."

   
1.0

becca (taken for 2 to 5 years) May 28, 2018

1 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"This is the best medication I have been given. It gave me my life back"

   
9.0

Sarah (taken for 10 years or more) March 3, 2018

2 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I have been taking lamotragine but find it ineffective for depression. I was misdiagnosed as bipolar. I am considering taking venlaflazine again which worked to treat the depression for 12 years. I am a little wary though, realising now that all medications have bad side effects that at the time we tolerate. The down sides of venlaflaxine were irritability and unable to really relax. Tooth grinding, I lost and cracked 2 teeth and an inability to think or talk about my problems, armoured and ignoring them. Is it better to live calmly with some depression than none?"

PPOd (taken for 10 years or more) February 22, 2018

1 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I started Effexor after not being able to take Paxil due to headaches, and felt like trash after a week on Paxil, sexual side effects from Paxil as well. On Effexor 37.5 mg I feel better, less depressed, don't have alot of energy, but have less depressive thoughts after a week my dose was upped to 75 mg. After a week on 37.5 mg I noticed it was almost impossible to orgasm. On 75 mg it is impossible for me to orgasm. This is making me want to stop it, and try to find something else that may not effect me in this way. I don't have an issue with getting an erection and performing, it's just I can't orgasm. I have even tried generic viagra "sildenafil" which does improve the erection but still can't orgasm."

   
5.0

Deppressor (taken for less than 1 month) December 18, 2017

5 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I've been on 75mg of venlafaxine for 6 or 7 years. It is good for me. Before Effexor, my emotions felt like being hit by a truck. After Effexor, it gives me a moment to THINK about things, rather than just disintegrating into a puddle on the floor. I still have feelings, but they're not as overwhelming and I don't feel like I HAVE to react to them. Side effects: sweating and tiredness. I take a lot of naps! Missing a dose: About an hour or two after my time to take my pill, if I forget to, I'd get tingly and dizzy. Withdrawal: I recently tried to stop taking Effexor cold turkey. I lasted 6 days. Intense anger, bursting into tears, a static feeling in my head, like a TV set on no channel, and a tingly feeling in my lips."

   
8.0

AfternoonMocha (taken for 5 to 10 years) October 22, 2017

9 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I have been battling with major depression/anxiety since I was 12. I’ve been admitted in a mental institution twice. I’m now 18 yrs old, I’ve literally been on every med you can name. I was put on a type of B/P med to calm me down. It has, but I’ve still been so utterly depressed I can’t even function correctly. I saw my doctor yesterday and he put me on Effexor 37.5mg once a day. I took it around 4:00 pm (I couldn’t wait, things have to get better) and now here I am lying on the couch at 5:09am, I’ve been up since 11, with a little bit of nausea. Cannot go back to sleep..BUT I already feel better.. the heaviness and sad dwelling feeling is gone. It hasn’t even been 24 hours and I can breathe again.. Taking it in the morning instead."

Anonymous October 5, 2017

5 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"After an escalating two year psychotic depression I finally sought help- I was suicidal and believed I was beyond help. Olanzapine eased the psychosis but the deep dark depression I was in was relentless. It took a year of finding the right fit, prozac and citalopram didn't help me at all. Finally I was put on Effexor at 225mg and have been on it for 3 months. It has made a massive difference in a short amount of time. Don't take as long as I did to find the right combo, I assumed these drugs were more or less the same so thought they just couldn't help me. Effexor saved the day, and with olanzapine, my life!"

   
9.0

BPGirl40 (taken for 1 to 6 months) September 21, 2017

6 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"It was alright and helped a bit however being on one of the highest doses, missing a dosage was abysmal, one of the worst experiences ever. Try to find something else."

   
4.0

Anonymous (taken for 2 to 5 years) September 16, 2017

2 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"37.5mg makes life liveable again. The experience of missing a dose is not fun. Otherwise, this drug saved my marriage and my job."

   
9.0

RibbledyDabbleFrabbit (taken for 2 to 5 years) August 22, 2017

13 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I am currently on 150 mg of effexor XR. It isn't the greatest but I noticed that I don't have random crying spells anymore and my depression eased a bit."

   
8.0

DaynaS (taken for 1 to 2 years) April 30, 2017

9 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I am sure Effexor has helped many people over the years. I was one of the first patients to take Prozac I was given ever increasing doses as my depression increased. At first, I was HEALED! I wound up in hospital with psychotic break, due to SSRI's. Effexor was given to me a few years later ( Doctors still did not correlate medication as possible issue ) and again I got more depressed. At this point I was taking a bi-polar med Lithium. The Dr. abruptly stopped Effexor from a high dose., and I do not remember the next month. I was on the payphone in a psych- ward talking to my Mom and came back. The nurses said I do not want to know what happened. I take my meds everyday, at the same time, see my Dr. every 3 months, and am well."

   
1.0

Experimental One (taken for 6 months to 1 year) February 25, 2017

5 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I never write reviews but I figured I had to share how truly life-changing Effexor has been for me. I've suffered with GAD and Major Depressive Disorder for quite some time. I was on and off of Prozac for about five years. When it stopped working, I began taking Effexor XR 37.5mg. I started feeling better, more calm, less anxious. Last year, someone I had dated for years and had recently broken up with passed away tragically. I was a disaster. My dosage was increased to 75mg, then 150mg, and now 225mg. Honestly - I don't know how I would have made it to where I am today without this medication. It has controlled my anxiety, my panic attacks and my depression. I still have bad days, I'm still in mourning, but I finally feel normal."

   
10

FreeAtLast55 February 10, 2017

26 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"This med was given to me to replace lexapro and klonipin I took the med as directed and had the worst week of my life. The vivid dreams caused me to believe my sister and friends we're sneaking around trying to take my house or shooting me and burning it down it was so real to me. The tremors were uncontrollable I didn't know what day it was, I was living a nightmare. I'm 55 with two adult children I couldn't drive walk work it made me a zombie. I wouldn't give this med to my worst enemy. Every side effect I had"

   
1.0

Veniceboy January 13, 2017

12 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"Never knew how powerful this drug is until I tried to replace it with Cymbalta. Within 2 days of switching, my anxiety was sky high and my depression was so severe that I literally was suicidal. Went back on it and these symptoms subsided quickly. By no means this is the perfect drug but it seems to be a bit better than others. I wish it would control anxiety better. I have to take lorazepam to control anxiety fully."

   
8.0

sadrin (taken for 1 to 6 months) December 2, 2016

12 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"My doctor put me on 37.5 mg regular (generic brand) for about 2 weeks and I was so tired and still depressed. So she upped my dosage to 75 mg XR. And after 2 days my anxiety was out of control and depressed so I had be watched 24/7. So I finally got off it after I switched backed to 37.5 before going cold turkey. I didn't have any withdrawal symptoms. Good luck to anyone on this medication."

   
2.0

Lindsaay (taken for less than 1 month) November 5, 2016

7 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I was prescribed Effexor after a really bad anxiety attack about 3 years ago. At first, it was really great. Less suicidal thoughts, my anxiety wasn't as bad, but I wasn't eating. I had absolutely no appetite whatsoever, I starved myself until I lost 20 lbs and they increased my dosage from 37.5 to 150 mg. It's years later and I now suffer from an eating disorder that I didn't before. The side effects; dizziness, bad coordination, insomnia, headaches, lightheadedness, and especially the fatigue, all impacted my life to the point where I dropped out of high school. The withdrawals, which occur after 24 hours of not taking the pill, make you feel inhuman. I was better before."

   
1.0

Really sleepy (taken for 2 to 5 years) September 21, 2016

13 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"Effexor has finally made me feel like myself again... Can't remember the last time I was me, it's been at least 7 or 8 years. Tried Lexapro, Wellbutrin, Zoloft with no relief and bad side effects. Celexa worked so-so. Effexor has given me my motivation and happiness back. Only side effects for me are night sweats and slight headache/dizziness if I forget a dose...worth it in my opinion to be me again! Don't forget counselling/ therapy too... Didn't feel the most helpful most days (I cried every time I went) but I can tell my maladaptive thought patterns have changed."

   
10

Zilla! (taken for 6 months to 1 year) September 9, 2016

27 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I've been taking Effexor XR 37.5 mgs for 8 days & the worse SEs are horrible fatigue & sweats. The 1st day I was light-headed but that went away. I skipped today to see if I got withdrawal symptoms & I did. Tomorrow I will go back on it. If the chronic fatigue continues I will have to figure which med to try next. For my depression to subside I would probably need a higher dosage but I don't think I could handle the SEs. I know for some people it works well at 150 mgs but I could never tolerate that dose."

   
5.0

wannabbetter September 6, 2016

4 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I just wanted to let you all know my current situation in regards to this medication. I have taken Effexor XR for 12-13 years. The overall results have been good. I just wanted to share this experience. I had a MIR for chronic abdominal pain 18 months ago. The MIR discovered a shadowing on my lungs. This shadow was caused by the Effexor XR. This shadow is what we experience while on this medication as a shortness of breath. I did furthur research and the Effexor XR does contribute to lung conditions that cause shortness of breath and difficulity in breathing while exerting yourself. I have undergone several MRI's showing different levels of this lung shadow. I am currently seeking other treatments for my depression."

Concerned Ellen August 17, 2016

18 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"Did not help me, and I gained weight."

   
3.0

LolliH August 17, 2016

2 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I've started taking Effexor XR recently at the lowest dose 37.5mg and the first day you get very nauseous even if you do eat beforehand, I felt so foggy. After a few days the side effects subsided so I upped my dosage to 75mg and the same thing happened. So I'd recommend when starting this medication you also have an anti nausea medication with it otherwise you'll have a few crappy days. This medication has benefited me the most out of all the others I tried because it brought back my focus."

   
6.0

major depression (taken for less than 1 month) July 23, 2016

17 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I've been on Effexor xr for 2 weeks and it's great. I had been on Zoloft before and it pooped out on me so my doc switched me to Effexor xr and after 2 days I started feeling good again. I take 37.5 mg per day. I come back to write here because I wanna give back to this forum and give hope for anybody that suffer from this like me. keep to try the med that suit for you. best wish!"

   
10

Asian July 8, 2016

30 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I have been taking Effexor for 13 months now. Initially I was prescribed 75 mg while hospitalized at an inpatient psychiatric facility but that was increased to 150 mg by the time I was discharged. Never in my life have I felt this way - normal!! My crying spells, anhedonia, suicidal ideations, psychosis... it's all gone gone gone! This medication has saved my life. I am so happy to take my meds every morning."

   
10

NurseSlacky (taken for 1 to 2 years) May 26, 2016

50 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"I've been taking venlafaxine 150mg xr for nearly 3 years along with an antipsychotic to treat bipolar 2. Having tried all kinds of anti depressants this is the one that's worked for me. The down side is the withdrawal symptoms should you miss a dose but these go away as soon as you take it again. Dizzy spells/feeling drunk is the only way I can describe them. It has a short half life of 7 hrs which indicates that they have these symptoms. I've had no side effects & would recommend venlafaxine over other antidepressants inc citelopram & mirtazipine."

   
10

Pollyp82 (taken for 2 to 5 years) May 25, 2016

21 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

"Diagnosis: a Chronic Clinical Depressive with a 40 year history who does not react to meds in a typical manner. After 6 months of juggling meds weekly at the clinic, finally got relief with a daily dose of 150 mg Effexor XR. Have not had Any episode of Depression since 2003. The side effects are more than tolerable as a tradeoff to be the happiest people on this planet instead of in perpetual hell."

   
9.0

iamerletheperle (taken for 10 years or more) May 15, 2016

42 users found this comment helpful.
Did you?   Yes   No   |   Report inappropriate

Page 1 2 3 Next

Learn more about Major Depressive Disorder

Micromedex® Care Notes

Symptoms and treatments

Hide