Tranylcypromine for Depression User Reviews (Page 5)

Brand names: Parnate

Reviews for Tranylcypromine

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wit...
Taken for 1 to 6 months
May 3, 2020

"4 weeks now on Parnate, and I'm feeling like my old self again! I can laugh again, take things in my stride, wake up with enthusiasm to face the day. My GP said, 'Most people are feeling more depressed right now with the social isolation and uncertainty of the pandemic, so this must be working.' It took me months of research and trepidation to try it, after a year of worsening depression due to carer stress. Had tried Zoloft, Pristiq, and Lexapro in the past. Food restrictions are manageable, no side effects apart from broken sleep. Recommended."

9 / 10

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dor...
Taken for 6 months to 1 year
February 9, 2019

"A decent medication, unlike many others. However, if you're one of the unlucky ones (like me) who get the afternoon somnolence, it turns out impractical to take long term. Parnate didn't completely resolve my depression but offered some relief compared to SSRIs, which don't do anything. I can imagine this being a perfect drug if you don't turn into a zombie in the afternoon."

6 / 10

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Ash...
Taken for 2 to 5 years
October 25, 2016

"Parnate, in my experience, has been the most effective AD for anxiety. For me, none of the SSRIs/SNRIs worked. I've taken 30-40 mgs for ~2 years on and off. It's not perfect. It has its issues. That said, it actually helps with anxiety, which is a. Caused no weight gain, no sexual issues. Side effects were: red eyes, not really being able to tolerate much alcohol, feeling a little 'weird.' Only thing to note is drug interactions. I stupidly took ecstasy while on this, which was a very fast way to a blackout, seizure, and ambulance bill. Do not take anything that will affect serotonin at the same time as this medication. Drug interactions are very serious. That said, food reactions, in my opinion, are exaggerated."

9 / 10

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"Of all the antidepressants I’ve tried, this one was by far the most effective. It was the first time I felt like, “this is what normal people feel like getting up in the morning.” The downside is the multiple interactions and food restrictions. I got more and more sensitive to food restrictions, to the point that one piece of salami would send my blood pressure to 160 and require my immediate blood pressure medicine. You need to be very careful what you eat, especially as you take it longer."

9 / 10

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Eul...
February 15, 2017

"My experience of tranylcypromine [Parnate] was very positive from the beginning. The first time I was administered 20 mg I felt suddenly much better than I had for weeks. I wanted to go outside and 'see the world.' So far, so good. Now comes the kick in the head. In the UK, 30 mg is the highest that they can prescribe. However, I tried up to 60 mg, and it has been beneficial, and I have come across blogs and psychiatric accounts on the web that suggest that this dose is OK in the USA. That would never happen here in the UK. The guidelines stop at 30 mg per day, which is unacceptable in the UK, especially since the price was increased to £25.00 per 28 tablets. I have had pressure applied from my GP to stop using this drug."

2 / 10

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Hal...
Taken for 6 months to 1 year
August 28, 2016

Tranylcypromine "Everyone responds differently to medications, and no two people are alike - so I kind of find these forums as being useless (if not borderline ridiculous). But just to share my experience... I have MDD (treatment resistant) along with complex PTSD. I have tried every medication under the sun (over 90 different meds) before finally being introduced to Parnate in March of 2016. I was initially started at 10 mg and eventually moved up to 60 mg within 3-4 months. It seemed to be somewhat helpful for my depressive symptoms, yet it created so many other horrific side effects along with it that life is now worse than ever. Never have I been on a med with so many unwanted side effects. I'd rather be severely depressed any day of the week."

2 / 10

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Gho...
Taken for 6 months to 1 year
July 10, 2019

"The heart palpitations from Parnate are my only complaint. I eat only fresh whole foods with no tyramine, but the heart palpitations are relentless on this drug. (No blood pressure problems with Parnate, just bad heart palpitations, which should not be happening considering that my cardiologist gives my test an A plus. It’s the only antidepressant that actually works for me, but now I must stop because the heart palpitations from Parnate are almost as bad as my depression. All that's left now is ECT, so I guess soon I can kiss my memory goodbye."

7 / 10

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Poo...
Taken for less than 1 month
October 30, 2021

Tranylcypromine "1983, severe anxiety, panic, and depression. Never suicidal, just crying all the time. Was forced into a psychiatric ward. Parnate was prescribed to myself and several other patients. Short story, another woman on the ward did not survive after eating aged cheese and bananas, which caused a fatal heart attack. My blood pressure plummeted to the point of my passing out. They would make me walk or run around the common room until it went up a bit and then give me my medication. Then I would pass out, and they would slap me across the face until I came to. Eventually, it put me into a coma. Doc said I was being uncooperative and required ECT. Shock treatment! I had one opportunity to escape during an outing, and I ran. Walked 13 miles to safety. Flew home to Vancouver the same day. Saw my regular doc, who immediately diagnosed severe hormone imbalance due to hysterectomy at age 27. Incompetent docs and Parnate nearly finished me!"

1 / 10

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Anonymous
Taken for less than 1 month
September 6, 2012

"I'm 62 and have suffered from depression ever since I can remember, and through the years have only had moderate success with all the other medicines. This one is horrible. After only two days, I was off the wall, breaking things, screaming, and other nasty responses. There is nothing like feeling hopeless again."

1 / 10

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Isu...
Taken for 1 to 2 years
March 3, 2020

Tranylcypromine "I was in acute withdrawal for five years from this dirty drug. The doctor had no clue what she was doing, nor what to do with me. I'm amazed I survived this torture. This is a dirty, dangerous drug. I now see there is 'Parnate Withdrawal Syndrome', this is an actual thing. Funny how true statistics of what this drug is doing to people aren't being collected?"

1 / 10

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Lol...
October 18, 2019

Tranylcypromine "This medication, Parnate, saved my life! No other medication worked. I've been taking it for 5 years and got my life back. Please, please bring it back."

10 / 10

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che...
Taken for 5 to 10 years
April 13, 2019

Tranylcypromine "Parnate really works for my depression and makes all other drugs for depression look like a joke."

10 / 10

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clo...
Taken for 10 years or more
May 22, 2018

Tranylcypromine "Parnate is my favorite antidepressant. It took me from suicidal to happy in less than 48 hours."

10 / 10

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Anonymous
Taken for 10 years or more
June 16, 2016

Tranylcypromine "When nothing else works long term, this is the one. Pain to have to watch what you eat since it's an MAOI, but it's better than not having it!"

9 / 10

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Gre...
Taken for 5 to 10 years
July 3, 2018

Tranylcypromine "Parnate is the only antidepressant worth taking."

10 / 10

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JRa...
Taken for 1 to 2 years
April 13, 2019

Tranylcypromine "This medicine literally saved my life. I've tried them all, and only the MAOI class of drugs actually work."

10 / 10

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Joh...
Taken for 5 to 10 years
November 15, 2012

Tranylcypromine "5 years on Parnate. Have tried numerous antidepressants and psycho drugs, this is the only one that has worked. Also take 2 mg/day Suboxone, it helps somehow."

9 / 10

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Ork...
November 9, 2012

Tranylcypromine "It may include some side effects, I used it, and I prefer Parnate with some side effects versus depression. That's my experience."

10 / 10

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mai...
September 14, 2017

Tranylcypromine "A miracle drug for my depression!!!"

10 / 10

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28 Report

Ros...
January 6, 2021

Tranylcypromine "Parnate was great for depression, but it didn’t really help with anxiety at all. Coming off it has been a nightmare! Going to try Nardil next if I can track supply down."

5 / 10

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Min...
Taken for 5 to 10 years
October 17, 2019

"Bring back Parnate. It's urgent for me!!!"

10 / 10

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Yea...
Taken for 10 years or more
November 25, 2024

Tranylcypromine "It's the best drug. More effective than SSRIs, ketamine, or amphetamines."

10 / 10

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dav...
Taken for 6 months to 1 year
October 24, 2017

"worked well for its immediate effects, did nothing noticeable in the long term."

5 / 10

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pea...
Taken for 1 to 2 years
October 31, 2024

"The only drug that's helped. Insomnia and fatigue are rough, but no such thing as a free ride. 10/10 med. Anxiety and depression are controlled."

10 / 10

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Hea...
Taken for 6 months to 1 year
May 3, 2023

Tranylcypromine "Drinking milk and other foods is not recommended. It made me so nauseous. Sadly I'd forget and then get sick."

4 / 10

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.