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Tramadol Hydrochloride ER User Reviews & Ratings

Tramadol Hydrochloride ER has an average rating of 5.7 out of 10 from a total of 15 reviews on Drugs.com. 27% of reviewers reported a positive experience, while 20% reported a negative experience.

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Reviews for Tramadol Hydrochloride ER

  • Ric...
  • Taken for 1 to 2 years
  • May 19, 2019

For Chronic Pain "I have CIDP (chronic inflammatory demyelinating polyneuropathy) in my hands, with the myelin sheath around the nerves in my fingertips destroyed (nerves are exposed). I also have sensory neuronopathy with chronic pain in the front of my thighs and lower legs. So yes, I'm in a lot of pain. I take Tramadol ER 200 mg in the morning and Tramadol 50 mg approximately 8 hours later, depending on how much I use my hands and fingers the first 8 hours of my waking hours. Tramadol in both doses works to allow me to do much more with my hands and fingers while clearly improving my way of life. Neither dose takes the pain away completely, but it certainly helps make life bearable. The only side effect I have is constipation, which I resolve with a stool softener."

10 / 10
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49 Report
  • Ben...
  • January 24, 2019

For Back Pain "I’m a college student. I have severe scoliosis in my back and need surgery kind of soon :( My doctor prescribed me Tramadol recently due to chronic back pain. I currently take 50 mg three times a day for moderate pain. Sometimes more. My pain still exists slightly, but my depression is killed by the Tramadol :) I feel energetic and motivated compared to before. I don’t seem to mind the back pain even though it’s still noticeable. Tramadol is the ultimate pain relief combo for me. However, I experienced withdrawal symptoms, which included vomiting, restless leg syndrome, tiredness, chills, and profuse sweating. Felt like a fever! Tramadol is great when you’re on it, but really hard when you stop. The only other side effect I hated was severe constipation. No joke, worst of my life. In conclusion, Tramadol helped me a lot for my chronic pain, but surprisingly useful for elevating my mood. I would have highly recommended Tramadol if getting off this drug was easier!"

6 / 10
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47 Report
  • Pat...
  • Taken for 1 to 6 months
  • November 1, 2019

For Chronic Pain "Tramadol is ineffective for my chronic pain. I've been given six times more Tramadol to replace morphine. Tramadol is a poor substitute for chronic pain relief, and copays are more than three times more expensive."

4 / 10
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28 Report

Frequently asked questions

  • Scu...
  • Taken for 10 years or more
  • April 8, 2016

For Chronic Pain "I was taking 50 mg of Tramadol 3/day for a total of 150 mg daily with no problem for over 10 years. My new doctor became nervous about prescribing a 3-month supply (270 pills) and switched me over to the 200 mg Extended-Release formula. I tried it for 2 weeks, and it doesn't work, so I started supplementing it with either Advil or Tylenol. This is definitely not good. I'm now taking a higher dose of Tramadol but have to take additional drugs."

1 / 10
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35 Report
  • joe...
  • Taken for less than 1 month
  • October 14, 2021

For Pain "In 2002, I had a major operation that left me with a huge long scar. As the scar was healing, I began getting pain from the right side of the scar, seems like the scar was not healing right. Each week for many months, I was going to the doctors to follow up on my operation. I kept telling the doctors I have pain coming from my scar, so the doctors kept saying each week to take Tylenol. Finally, the pain was too great, and I really let them know I've been suffering for a long time with this bad pain, and Tylenol has not done anything. They gave me Tramadol, when I took the first pill, it did nothing. The second pill knocked out the pain completely, and it never came back. I felt immediate relief, finally. I disagree with what I read about taking this medication every day, not as needed, everyone's pain is different. Doctors are put in a situation, told not to prescribe opiates. Doctors are being pushed around by superiors, they lose more and more of their freedom to be a doctor."

10 / 10
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14 Report

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  • Bar...
  • Taken for 1 to 2 years
  • March 22, 2025

For Back Pain "I was prescribed Tramadol 100 mg ER for osteoarthritis of the spine, after 3 rear-end collisions and being kicked in the gut by a PT with combat boots. It did take the pain away for me, and I do believe now that it changes your mood for the better! I was taken off of it because I was to have surgery per pain management. I had a second opinion for back surgery to make sure I was doing the right thing. Back pain definitely became unbearable without Tramadol! The pain doctor allowed me to have some, then for 2 months, I didn't get medication! The second doctor opinion said I had 'soft bones' and to have my doctor put me back on Tramadol because the surgery wouldn't take! I canceled my surgery and told my pain doctor that I was told to go back on them because I can't have surgery! After restarting Tramadol, they weren't working for my pain. The pain doctor was decreasing the percentage of Tramadol, I believe because I was getting itchy skin and had this before due to fillers in drugs! So, I still want to get surgery but need pain relief until then!"

9 / 10
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1 Report
  • sdh...
  • Taken for 10 years or more
  • May 8, 2019

For Pain "I have basilar migraines for 20 years, and I tried all other drugs with different MDs, and finally, the neurologist from UCSD put me on Ultram, which worked for the basilar migraines, and the average of pain is at the very, very lowest now."

10 / 10
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20 Report

More FAQ

  • ugl...
  • Taken for 6 months to 1 year
  • May 11, 2021

For Chronic Pain "I take 300 mg tramadol ER daily, with low-dose Norco 500 mg/750 mg as needed, usually twice daily. I have fibromyalgia and other undiagnosed conditions, extreme pain untreated, but I can live with these drugs, otherwise, it's torture. I am so drugged out like a zombie, but anything to ease the pain. Life is short, enjoy what you can now."

7 / 10
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15 Report
  • Ray...
  • Taken for less than 1 month
  • April 12, 2022

For Chronic Pain "I just started a 30-day regimen of 3 a day 50 mg, and so far I’m not feeling the pain relief! I have severe pain in my neck to my shoulder! Disc 2-7 in my neck are messed up! Doctor asked if I wanted to try 100 mg extended relief 2 times a day. I think I should have switched to something else! What do you all think?"

4 / 10
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9 Report
  • Moe...
  • July 3, 2016

For Back Pain "The first 3 days I took Tramadol Hcl tablets, 1/2 tablet in the morning and the other half at night, as per my doctor's orders. They were 50 mg tablets. Had a slight adverse reaction the second time they were prescribed for me, so had to go slow. Most of the pain disappeared for those 3 days. On the fourth day, I took my usual dose-1/2 of a 50 mg tablet with a full glass of water, as usual. Within a few hours, I began to experience some of the side effects listed: nausea, dizziness, diarrhea, headaches, itchiness, upset stomach, and lightheadedness. I also had a few extra side effects: constant belching, acid reflux, and shortness of breath. These events lasted for several hours."

1 / 10
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22 Report
  • DHJ...
  • Taken for 5 to 10 years
  • July 19, 2016

For Chronic Pain "I have been taking Tramadol ER 100 milligrams 3 times a day for over 6 years. I have found out that in the beginning it helped, but now as my pain has increased and my disease has become more severe, it doesn't help at all. I have never experienced any side effects other than constipation when I add it with the rest of my meds, such as Vicodin, to help with the pain. I do realize that when I am taking the Vicodin, it does give me the itches. Other than that, I can't say I've experienced any other side effects."

4 / 10
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18 Report
  • Ran...
  • October 13, 2022

For Back Pain "I was prescribed Tramadol 50 mg but found it not very effective and only for a short duration. Doctor switched me to 100 mg ER, which is supposed to be effective for up to 24 hours, but it starts to wear off after about 4 hours and seems ineffective after 8 hours. I supplement it with Tylenol Arthritis Strength ER, as the doctor suggested. I can't use NSAIDs as I'm taking Eliquis or I'd use Advil, which provided better pain relief than Tylenol."

7 / 10
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5 Report
  • Ebg...
  • September 11, 2021

For Pain "I was taking 50 mg tramadol and thought 100 ER might be better. That was a mistake. Like taking nothing at all. Useless."

2 / 10
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5 Report
  • Tob...
  • Taken for 2 to 5 years
  • August 5, 2022

For Back Pain "Works well for low-grade back pain. For sciatica, you need something stronger plus an anti-inflammatory like Motrin or Celebrex."

7 / 10
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3 Report
  • Anonymous
  • Taken for less than 1 month
  • January 30, 2018

For Chronic Pain "Severe headache during dosage - one tablet. Taken at night, 10 pm. Woken with feeling of anxiousness, 2/3 am. Hallucinating during this time."

4 / 10
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7 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.