Tramadol Hydrochloride ER (tramadol) Drug Interactions
A total of 757 drugs (4380 brand and generic names) are known to interact with Tramadol Hydrochloride ER (tramadol).
- 442 major drug interactions (2206 brand and generic names)
- 311 moderate drug interactions (2159 brand and generic names)
- 4 minor drug interactions (15 brand and generic names)
Check for interactions with Tramadol Hydrochloride ER (tramadol)
Common medications checked in combination with Tramadol Hydrochloride ER (tramadol)
- amlodipine
- atorvastatin
- clonazepam
- cyclobenzaprine
- furosemide
- gabapentin
- ibuprofen
- levothyroxine
- lisinopril
- losartan
- Lyrica (pregabalin)
- meloxicam
- metformin
- omeprazole
- pantoprazole
- prednisone
- simvastatin
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
Tramadol Hydrochloride ER (tramadol) alcohol/food Interactions
There is 1 alcohol/food interaction with Tramadol Hydrochloride ER (tramadol)
Tramadol Hydrochloride ER (tramadol) disease Interactions
There are 9 disease interactions with Tramadol Hydrochloride ER (tramadol) which include:
- Acute Alcohol Intoxication
- Drug Dependence
- Liver Disease
- Renal Dysfunction
- Seizure Disorders
- Acute Abdominal Conditions
- Intracranial Pressure
- Respiratory Depression
- Suicidal
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
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