Tramadol Hydrochloride ER Interactions
There are 715 drugs known to interact with Tramadol Hydrochloride ER (tramadol), along with 12 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 319 are major, 393 are moderate, and 3 are minor.
- View all 715 medications that may interact with Tramadol Hydrochloride ER
- View Tramadol Hydrochloride ER alcohol/food interactions (1)
- View Tramadol Hydrochloride ER disease interactions (12)
Most frequently checked interactions
View interaction reports for Tramadol Hydrochloride ER (tramadol) and the medicines listed below.
- acetaminophen
- albuterol
- amlodipine
- aspirin
- atorvastatin
- baclofen
- cyclobenzaprine
- duloxetine
- furosemide
- gabapentin
- ibuprofen
- levothyroxine
- lisinopril
- losartan
- Lyrica (pregabalin)
- melatonin
- meloxicam
- metformin
- Metoprolol Succinate ER (metoprolol)
- omeprazole
- ondansetron
- pantoprazole
- prednisone
- rosuvastatin
- tamsulosin
- tizanidine
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
Tramadol Hydrochloride ER alcohol/food interactions
There is 1 alcohol/food interaction with Tramadol Hydrochloride ER (tramadol).
Tramadol Hydrochloride ER disease interactions
There are 12 disease interactions with Tramadol Hydrochloride ER (tramadol) which include:
- gastrointestinal obstruction
- acute alcohol intoxication
- drug dependence
- respiratory depression
- gastrointestinal conditions
- hypoglycemia
- hypotension
- intracranial pressure
- liver disease
- renal dysfunction
- seizure disorders
- suicidal
Report options
More about Tramadol Hydrochloride ER (tramadol)
- Compare alternatives
- Reviews (15)
- Latest FDA alerts (4)
- Side effects
- Dosage information
- During pregnancy
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Tylenol
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Botox
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Cymbalta
Cymbalta (duloxetine) is used to treat major depressive disorder, general anxiety disorder and ...
Naproxen
Naproxen is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Oxycodone
Oxycodone is an opioid analgesic used to treat moderate to severe pain; it has a high potential for ...
Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Duloxetine
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant used to ...
Aspirin
Aspirin is used to treat mild to moderate pain and to reduce fever or inflammation. Learn about ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.