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Zepbound User Reviews & Ratings (Page 3)

Zepbound has an average rating of 8.8 out of 10 from a total of 404 reviews on Drugs.com. 83% of reviewers reported a positive experience, while 1% reported a negative experience.

Reviews for Zepbound

Commonly mentioned side effects
  • Suz...
  • Taken for 6 months to 1 year
  • February 26, 2025

For Weight Loss (Obesity/Overweight) "I began my weight loss journey in late January 2024. Over the next 12 months, I lost 40 pounds. However, I've hit a plateau for the past four months, since the end of November 2024, and it's now February 25, 2025. I still need to lose at least another 40 pounds. Zepbound has been a significant help in my journey. My clothes fit much better, and I've gone from a size XXL to a medium. In addition to Zepbound, I also strength train, maintain a healthy diet, and track my calorie intake. The only side effects I've experienced with Zepbound are occasional acid reflux, mild nausea, and some constipation. Currently, I am on 12.5 mg, but my doctor has decided to update my dosage to the 15 mg to see how I do on that dosage. Hopefully, it will kick me over the plateau and I will end up losing the next 40 pounds that I need to. Other than that, I love Zepbound. I think it’s great."

9 / 10
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  • Sta...
  • Taken for 1 to 6 months
  • December 7, 2024

For Weight Loss (Obesity/Overweight) "They keep upping the price, and now I can’t afford it. I lost 43 pounds. It lowered my blood pressure. Dehydration, constipation, and sulfur burps, though. I had a heart attack from the dehydration. I’ve got that managed now-drinking electrolytes. I don’t want to give up, though, but I can’t afford $680 a month."

7 / 10
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1 Report
  • DAS...
  • Taken for less than 1 month
  • May 29, 2025

For Obstructive Sleep Apnea/Hypopnea Syndrome "Starting 4th week of 2.5 mg. It wears off some by the end of the week. Dr. raised it to 5 mg for the next month's prescription. I am down 10 lbs in 3 weeks. Appetite is now easy to control and say no to the food/snack crazies. Very slight constipation is the only side effect I have noticed. It does work but is not affordable for me. $350 for the 1st month was the vial and syringe and out of pocket. Easy to use. Insurance declined it. $450 for the 2nd month. I can't afford it. I have researched it and found that you can buy the tirzepatide peptides online for considerably less money. I may regret it, but I am going to try it. I have seen very high numbers of happy people who went this route."

10 / 10
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Frequently asked questions

  • Ano...
  • Taken for 1 to 6 months
  • May 29, 2025

For Obstructive Sleep Apnea/Hypopnea Syndrome "Dosage 2.5. Effective for sleep apnea and weight loss. Having side effects including queasiness, lightheadedness, diarrhea, constipation, Vitamin B12 blood test elevated to 1270. Starting weight 156. Now 147 after 7 doses."

7 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • June 19, 2025

For Weight Loss (Obesity/Overweight) "I am up to a 12.5 dose, almost 4 months on Zepbound. I have only lost 11 lbs. I am on a calorie-restricted diet, 1400 cal per day. I don’t feel a lot of hunger and my cravings are not many. I am disappointed in the loss rate, but if it keeps me from gaining back the weight, I’ll be happy. My only side effects have been constipation and minor nausea."

6 / 10
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  • Boi...
  • Taken for 1 to 6 months
  • May 30, 2025

For Weight Loss (Obesity/Overweight) "I am a 67-year-old male. I have been taking Zepbound for 3 1/2 months now. Currently taking the 7.5 strength. I have just reached the 50 lb threshold or just under 20% of my body weight lost. The drug is not a magic potion as you still have to eat the right calorie foods, but the drug makes it much easier as I am really never very hungry and fill up quicker. My biggest struggle has been wanting to snack at night from boredom. As for side effects, I belch more, early on, I experienced some upset stomach but found if I eat a few crackers with peanut butter, I feel a lot better. I also experience some constipation, but my doctor said that was mainly due to the reduced amount of calories I am consuming. Overall, I am thrilled with the experience and results. I plan on losing another 5-10 pounds, then work on maintaining new eating habits. My doctor suggested I order some extra of the 5 strength and keep it back to take if I start sliding back into old eating habits. I plan on doing that."

10 / 10
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  • Sus...
  • Taken for 1 to 6 months
  • April 7, 2024

For Weight Loss (Obesity/Overweight) "Nausea and constipation. I started on 2/22/2024 at 207 pounds, and now on 4/7/2024, I weigh 180 pounds."

8 / 10
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22 Report

More FAQ

  • Cry...
  • Taken for 6 months to 1 year
  • February 21, 2025

For Weight Loss (Obesity/Overweight) "I've lost 67 lbs in 10 months. Only side effects have been some constipation and slight nausea. This has been a life changer for sure!"

9 / 10
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  • Ano...
  • Taken for less than 1 month
  • June 2, 2025

For Weight Loss (Obesity/Overweight) "I am 2 weeks on Zepbound, have lost 5 lbs. It curbs my appetite, no side effects except constipation. So far I am very pleased with it."

10 / 10
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  • Jmd...
  • Taken for 1 to 2 years
  • July 11, 2024

For Weight Loss (Obesity/Overweight) "Blurriness in right eye, constipation, rapid heartbeat, lightheadedness"

9 / 10
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  • Tho...
  • Taken for 6 months to 1 year
  • December 11, 2024

For Weight Loss (Obesity/Overweight) "Love Zepbound; in 8 months, down 40 pounds; minimal side effects, some constipation, but gone in a few weeks."

10 / 10
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  • Pat...
  • Taken for 1 to 6 months
  • September 21, 2024

For Weight Loss (Obesity/Overweight) "I have lost 43 lbs in less than 4 months. Works great, but I have had side effects of a drop in blood sugar, where I almost passed out, very tired, and constipation."

8 / 10
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  • Nic...
  • Taken for less than 1 month
  • August 25, 2024

For Weight Loss (Obesity/Overweight) "I took my second 2.5 mg shot yesterday and am down 3 pounds. The shot is easy to administer and painless. I have experienced constipation and painful hives on my neck right after taking."

9 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • July 1, 2025

For Weight Loss (Obesity/Overweight) "Zepbound has been great. Best on the market. Weight loss is adequate. Side effect of constipation, low energy, maybe a little anxiety."

10 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • May 31, 2025

For Weight Loss (Obesity/Overweight) "It's working moderately to curb my appetite. I have experienced a change in bowel pattern and constipation."

6 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.