Zepbound and Constipation: What Users Say (Page 3)

• Sta...
• Taken for 1 to 6 months
• December 7, 2024

For Weight Loss (Obesity/Overweight) "They keep upping the price, and now I can’t afford it. I lost 43 pounds. It lowered my blood pressure. Dehydration, constipation, and sulfur burps, though. I had a heart attack from the dehydration. I’ve got that managed now-drinking electrolytes. I don’t want to give up, though, but I can’t afford $680 a month."

• tri...
• Taken for 6 months to 1 year
• September 2, 2025

For Weight Loss (Obesity/Overweight) "After taking this medication since February of 2025 and currently being at a 10 mg dose, I can say I got a ton of side effects and still do. I get injection site reactions I'm told to ignore because it was swelling but now is just itchy. I get constipation and the urge to go poop even when I don't have to go. Stomach aches are killer and literally leave me lying in bed unable to move. But symptoms are worst during the weekend as I take my meds on a Friday. Leading me to be unable to make plans on Saturdays or Friday evenings. I have so far lost 35 lbs over these 7 months with minimal exercise and some healthy dieting. My goal weight is 160 and I'm currently 255 down from 290 starting weight. I'm down 10% body fat. The longer I stay on my current dose, the less I feel the intensity of the symptoms, but I also still have appetite issues. As in I'll eat, and an hour later I'll be hungry again because I was unable to fill myself earlier. Or I wake up in the middle of the night to eat."

• DAS...
• Taken for less than 1 month
• May 29, 2025

For Obstructive Sleep Apnea/Hypopnea Syndrome "Starting 4th week of 2.5 mg. It wears off some by the end of the week. Dr. raised it to 5 mg for the next month's prescription. I am down 10 lbs in 3 weeks. Appetite is now easy to control and say no to the food/snack crazies. Very slight constipation is the only side effect I have noticed. It does work but is not affordable for me. $350 for the 1st month was the vial and syringe and out of pocket. Easy to use. Insurance declined it. $450 for the 2nd month. I can't afford it. I have researched it and found that you can buy the tirzepatide peptides online for considerably less money. I may regret it, but I am going to try it. I have seen very high numbers of happy people who went this route."

• NDH...
• Taken for 6 months to 1 year
• September 4, 2025

For Weight Loss (Obesity/Overweight) "Zepbound has really helped with food cravings and appetite. It has been almost a year since I started and I have lost 65 lbs. I had severe constipation at first but have learned to manage it now with stool softeners daily. I had tried Ozempic at first but didn't have much success on it and switched to Zepbound when my insurance covered it. Now still being on 15 mg, I do seem to have achy muscles that just don't go away and it makes it hard to sleep, so that is my only concern now. Wondering now on my treatment for long-term maintenance to keep weight off."

• Boi...
• Taken for 1 to 6 months
• May 30, 2025

For Weight Loss (Obesity/Overweight) "I am a 67-year-old male. I have been taking Zepbound for 3 1/2 months now. Currently taking the 7.5 strength. I have just reached the 50 lb threshold or just under 20% of my body weight lost. The drug is not a magic potion as you still have to eat the right calorie foods, but the drug makes it much easier as I am really never very hungry and fill up quicker. My biggest struggle has been wanting to snack at night from boredom. As for side effects, I belch more, early on, I experienced some upset stomach but found if I eat a few crackers with peanut butter, I feel a lot better. I also experience some constipation, but my doctor said that was mainly due to the reduced amount of calories I am consuming. Overall, I am thrilled with the experience and results. I plan on losing another 5-10 pounds, then work on maintaining new eating habits. My doctor suggested I order some extra of the 5 strength and keep it back to take if I start sliding back into old eating habits. I plan on doing that."

• Cry...
• Taken for 6 months to 1 year
• February 21, 2025

For Weight Loss (Obesity/Overweight) "I've lost 67 lbs in 10 months. Only side effects have been some constipation and slight nausea. This has been a life changer for sure!"

• Jmd...
• Taken for 1 to 2 years
• July 11, 2024

For Weight Loss (Obesity/Overweight) "Blurriness in right eye, constipation, rapid heartbeat, lightheadedness"

• Ano...
• Taken for less than 1 month
• June 2, 2025

For Weight Loss (Obesity/Overweight) "I am 2 weeks on Zepbound, have lost 5 lbs. It curbs my appetite, no side effects except constipation. So far I am very pleased with it."

• Ano...
• Taken for 1 to 6 months
• May 31, 2025

For Weight Loss (Obesity/Overweight) "It's working moderately to curb my appetite. I have experienced a change in bowel pattern and constipation."

• Tho...
• Taken for 6 months to 1 year
• December 11, 2024

For Weight Loss (Obesity/Overweight) "Love Zepbound; in 8 months, down 40 pounds; minimal side effects, some constipation, but gone in a few weeks."

• Pat...
• Taken for 1 to 6 months
• September 21, 2024

For Weight Loss (Obesity/Overweight) "I have lost 43 lbs in less than 4 months. Works great, but I have had side effects of a drop in blood sugar, where I almost passed out, very tired, and constipation."

• Nic...
• Taken for less than 1 month
• August 25, 2024

For Weight Loss (Obesity/Overweight) "I took my second 2.5 mg shot yesterday and am down 3 pounds. The shot is easy to administer and painless. I have experienced constipation and painful hives on my neck right after taking."

• Ano...
• Taken for 1 to 6 months
• July 1, 2025

For Weight Loss (Obesity/Overweight) "Zepbound has been great. Best on the market. Weight loss is adequate. Side effect of constipation, low energy, maybe a little anxiety."