Tirzepatide and Fatigue: What Users Say (Page 4)

• mas...
• Taken for 1 to 6 months
• August 23, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "Lost weight in the first few weeks. Some issues with belching and diarrhea for the first several weeks, which declined over time. But then, after approximately 6 weeks, no weight loss was noted. Still eating less, so hoping that the decreased intake of calories would reduce weight. Then had COVID, so had to miss a week, stayed on original dosage, no weight loss. Then, when dosage increased after the 3rd month, symptoms returned: upset stomach and diarrhea. During the same period, slightly elevated temperature, fatigue, headaches. Lost from 240 to 218 in 4 months, so cost was $100 per pound."

• Har...
• Taken for 2 to 5 years
• January 17, 2025

"Does work to lower blood sugar/A1C. Also works to lose weight. Over long-term use, it seems to allow for slight weight increase. Side effects include loss of appetite, fatigue, burps, stomach pain, nausea, and gastroparesis. After about two months of use, I developed an extreme sensitivity to touch. My skin became very painful all over, feeling like a mild sunburn with a horrible sensation of severe chills all the time. I am trying to tolerate the chills, but it is very severe."

• Dee...
• Taken for 1 to 6 months
• May 5, 2023

Tirzepatide for Type 2 Diabetes "I started taking Mounjaro 9 weeks ago and lost 12 lbs in the first 5 days. Since then, I haven't had an insulin injection, and my blood sugar levels are good. I've been insulin-dependent for almost 20 years and overweight for just as long. I've now lost 33 lbs in 9 weeks, which is great. However, I've experienced some negative side effects, such as nausea, heartburn, dizziness, and fatigue. Despite eating what I should and drinking lots of water, I still feel nauseous and dizzy most days, which makes it difficult to exercise. I only get 2 good days out of the week where I feel like doing something besides sitting. I've only vomited once, but the feeling of needing to do so is always present on a daily basis. Since starting this medication, my weakness has increased instead of declined, which is frustrating because it limits my ability to exercise properly. Overall, while weight loss and improved blood sugar levels are positive outcomes, the negative side effects make it challenging to maintain a good quality of life."

• Flo...
• Taken for less than 1 month
• December 22, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "This medicine has made me so sick. I will never take it again. I have not eaten in over five days. I am so weak, I feel like my blood sugar is low. I am not a diabetic, I only wanted to lose a few pounds. I have been sick, nauseous, vomiting, fatigue, diarrhea. Until I got everything out of my belly, my belly felt full, even when I did not eat. Constant belching. My food does not taste good. I am miserable. I’m sure it has great benefits. My other family members took it, as for me, whom is diabetic, extremely curvy, but just wanted to lose excess belly fat. I probably should’ve just gone to the gym, exercised more, or even worn a waist trainer. To me, in my opinion, it’s not worth it."

• kin...
• Taken for 1 to 6 months
• May 19, 2025

Tirzepatide for Obstructive Sleep Apnea/Hypopnea Syndrome "Caused diarrhea, fatigue, kidney problems on lowest dosage for 4 months."

• Ano...
• Taken for less than 1 month
• May 14, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I have lost 14 lbs in 4 weeks. Extreme fatigue and a little nausea. A little shortness of breath when walking. Feeling weak."

• Mor...
• Taken for less than 1 month
• July 21, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "So far, so good. I am suffering from the nauseated feeling, burping, fatigue, and muscle cramps. I'm at 2.5 level, week 3. I'm definitely eating a lot less."

• Ano...
• Taken for 1 to 6 months
• June 7, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "Lost 22 pounds! But… hair started falling out and feel fatigued!"

• Oti...
• Taken for less than 1 month
• April 20, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "Lost 5 lbs the first week. Lots of diarrhea. Feeling fatigue fairly often. Rarely feel hungry. Easy to go most of the day without eating."

• Jos...
• Taken for 1 to 6 months
• January 11, 2023

Tirzepatide for Type 2 Diabetes "No issues until I began the 7.5 mg dosage. I am achy, tired, very low energy for the second and third day after the shot. These side effects wear off just in time to take the next dose."

• Rod...
• Taken for 1 to 6 months
• May 11, 2025

Tirzepatide for Type 2 Diabetes "Too many side effects when first taken, stomach pain, awful burps, fatigue, and body aches last 2-3 days. Need to be careful to eat small plain meals to survive."

• Jul...
• Taken for 1 to 6 months
• October 22, 2024

For Weight Loss (Obesity/Overweight) "Fine, some burning tongue sensation, tiredness, fatigue."

• Rob...
• Taken for 6 months to 1 year
• August 1, 2024

Tirzepatide for Type 2 Diabetes "Has been effective in controlling sugar level. I'm at 7.5 now. Side effects I've had and have are severe headaches, bloating, nausea, low energy. Take it every Friday. Sometimes hard to get."

• Ano...
• Taken for 1 to 6 months
• July 17, 2025

For Obstructive Sleep Apnea/Hypopnea Syndrome "Tirzepatide has helped me lose 12 pounds in three months. It also curbs my already low appetite, so that I eat less. The only side effect I’ve noticed is fatigue."

• Ano...
• Taken for 1 to 6 months
• July 1, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "Zepbound has been great. Best on the market. Weight loss is adequate. Side effect of constipation, low energy, maybe a little anxiety."

• Law...
• Taken for 1 to 6 months
• June 8, 2023

Tirzepatide for Type 2 Diabetes "Has been good. Some constipation. Some fatigue. Good weight loss and hunger control."

• Rho...
• Taken for 6 months to 1 year
• March 25, 2023

Tirzepatide for Type 2 Diabetes "Fatigue that has not gone away after several months of use. Nausea for the first 24-36 hours after injection. Constipation that goes away 2-4 days after injection."