Tirzepatide and Burping: What Users Say (Page 2)

• WVN...
• Taken for 1 to 6 months
• December 27, 2022

Tirzepatide for Type 2 Diabetes "I started on the 2.5 dose in October, my doctor felt that the weight loss would help with my joint pain and lower my A1C. From day 1, I was extremely nauseous, had no desire to eat, had sulfur burps, and had constipation. I spoke with my doctor, who encouraged me to ride it out. On week four, I was stepped up to the 5 mg dosage. The doctor called in Zofran for stomach issues. On week six, I called her and said I could no longer function. During this time, I was so fatigued and was having heart palpitations and was barely able to walk 20 feet without being totally exhausted. I chalked it up to being so nauseous and not eating. Then my legs started to burn like I had walked up a steep hill and felt so sore and bruised I could barely sit. That week, I had my follow-up appointment with my doctor. I told her about my symptoms, and she said that rhabdomyolysis is not a side effect of Mounjaro. I was never dehydrated, but my CK levels were still 440 two weeks off the medication! Eight weeks later, and no improvement!"

• Ano...
• Taken for 1 to 6 months
• August 15, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I was on Wegovy for a few months starting last year. I had GI issues going on and ended up getting off Wegovy in January of this year. I had gallbladder removal surgery in March. Issues went away. I consulted with my GI doctor to see if I could get back on Wegovy. He said I should be fine. Went to my PCP and asked about getting back on Wegovy. She recommended Zepbound as “side effects are less.” I’ve been on Zepbound for 3 months now. Lowest dose. After the second day of injection, I get the worst sulfur burps and diarrhea. Once I have a sulfur burp, the diarrhea is inevitable. It’s gotten to the point where it wakes me up in the middle of the night and I have to use the bathroom. This just started happening within the last month. It usually lasts about a day. Never had these issues with Wegovy. In fact, Wegovy worked much quicker with me as far as losing weight. Didn’t have these burps and diarrhea when I took it for months."

• Bgd...
• Taken for 1 to 6 months
• October 27, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "Outstanding! 59 yr old male. Started this journey at 251 lb. Just wrapping up the first month of 2.5 mg and have already dropped 15 lb! Down to 236! Moving to the 5 mg next week and cannot wait to keep moving forward! Other than a few extra burps, no side effects to speak of! The cost is an issue until I hit my deductible (as I have a high deductible plan), but if I am gonna meet the deductible, it may as well be sooner rather than later! This stuff is a game changer! No longer constantly thinking about the next meal!"

• 1 d...
• Taken for 1 to 6 months
• July 18, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "I have had zero issues with the drug when I do right. If I overeat, I have diarrhea and sulfur burps for sure. When I start my day with protein and coffee, and drink lots of water, I have zero issues. But if I mess up like I did this week (ate breakfast, lunch, happy hour, snacked), I was up all night in a world of hurt, and I still haven't fully recovered. I haven't noticed a significant weight loss in 5 weeks (10 pounds), but it’s been steady. Just DO NOT OVEREAT and drink plenty of water."

• Sev...
• Taken for 1 to 6 months
• March 25, 2025

Tirzepatide for Type 2 Diabetes "Type 2 - I had been on Ozempic. It made me vomit/diarrhea, had Charley horses and hand tremors, and I was belching acid. After 3 months, my Endo switched me to Mounjaro, stating it was stronger, but many people tolerate it better. Week one, I was sick six days. All the same symptoms I had on Ozempic, only more severe. Heart rate 15 beats higher per minute. Week two, I was sick five days. Week three, within 12 hours, all the same symptoms began, and more. The vomiting was severe (mouth and nose). The belching was rank smelling/tasting. Diarrhea. My appetite was definitely curbed. My belly sounded like a flood of water flowing through my innermost pipes but felt numb. Eyes were so dry. My watch alerted me that at night my respiration rate was dipping to 7.5. (Did not even know my watch tracked that!) My heart rate dipped to 45. My blood sugar went to 43. Felt like I was not going to breathe or control peeing. And more! Day five, I ended up in the hospital in AFIB with a high heart rate. ICU."

• Pro...
• Taken for 6 months to 1 year
• February 25, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I’ve been on Zepbound since 8/1/24 (305 lbs, 5’6). So far, I lost 65 lbs, I’m 45 lbs away from my goal. My current dose is 10 mg. I experience side effects within 24 hours of injection administration, ranging from nausea, vomiting, belching, diarrhea, abdominal pain, fatigue, and dizziness. The side effects last about 24-36 hours. The medication definitely decreases my appetite and cravings. My doctor stopped my BP medication as I continue losing weight and my BP readings are good. My husband has noticed that I stopped snoring, lol. My plan is to reach my weight goal and stop the medication. I have changed my relationship with food. I look at food more as fuel for my body instead of indulging and overeating. I also introduced portion control and exercise, mostly walking and swimming. My insurance covers the medication."

• Din...
• Taken for less than 1 month
• December 10, 2024

Tirzepatide for Type 2 Diabetes "In the two doses, my blood sugar has been lower, my appetite has diminished, and I had no side effects. At the end of the second week (Saturday), I woke up during the night with stomach pain, diarrhea, and belching. After 6 hours, I finally vomited up undigested food that had been in my stomach for over 12 hours. It looked like I had just eaten. I avoided all food until Sunday morning, eating 1/2 of a plain English muffin. I had Lipton chicken soup, a piece of Bavarian pretzel, and a few french fries (picking from my wife’s meal). Monday, I finally felt hungry and had a Whopper Jr. (not a good choice I know), and Tuesday I woke up with food sitting in my stomach and one diarrhea BM. NOTE: I have not taken dose #3, nor do I plan to. This is slowing my digestion down too much. I have never had digestive issues, and I’m not going to start now."

• Mar...
• Taken for 1 to 6 months
• October 28, 2024

Tirzepatide for Type 2 Diabetes "I started taking Mounjaro 2.5 mg in March of this year (2024). Every month, my doctor increased my dose to the next level. I was put on the medication to help with my A1C because it would go up and down but not at a normal number. After 3 months, it went from a 7 to 4.5. I was so happy with the result. I am currently on 15 mg and I am down 50 lbs (over 6 months) and A1C is staying at 4.5. My original goal was 30 lbs by September and 60 by next March. I am so excited that I am already close to my year weight goal loss. The only side effects that I have had were the sulfur burps, which I figured out how to control and prevent and stop. And occasional constipation, which I just increased fiber intake to help. Everyone's experience is different. I went into taking it and researching all the side effects and being careful. I am thankful to my doctor for helping me, and I am happy with the results so far."

• Chi...
• Taken for 6 months to 1 year
• June 15, 2023

Tirzepatide for Weight Loss (Obesity/Overweight) "I have been on Mounjaro for almost a year. Started at 194 lbs, now averaging 145-150 lbs. In the beginning, I had the usual gastro effects - upset stomach, diarrhea, and no appetite even for water. Despite eating low calories, I lost slowly, about 1 lb a week. I had no energy to work out. If I tried staying on lower doses to minimize side effects, then the appetite would come back. After a few months, the gastro effects mostly went away, and I am left with sulfur burps, fatigue, irritability, and a general meh attitude about everything. I am someone who I would say has an addictive personality, and addiction runs in my family, and this drug works on your reward systems as well, so I’m not surprised it takes away my motivation. Despite the bad, it’s the only thing that has worked for me for weight loss. Currently, I take the injection every 14 days to minimize side effects and also to keep it affordable. Doing this keeps me at the weight I’m at, which I would like to be about 10 pounds less."

• Far...
• Taken for 6 months to 1 year
• January 29, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I’ve lost 60 pounds on Zepbound and maintain the same lifestyle as before, with the exception that I don’t think about eating much and sometimes have to be intentional about eating anyway. My side effects are minimal, just sulfur burps on an increased dose, but generally disappear after a while. I take Pepto to help with that. I lost weight steadily in the beginning and slowed down after 6 months. I’m one year into it and still not down to where I want to be, 20 more pounds to go."

• Bev...
• Taken for 1 to 6 months
• January 2, 2023

Tirzepatide for Type 2 Diabetes "I have been on Mounjaro to help lose weight for 8 weeks, 4 at 2.5 mg & 4 at 5 mg and have not lost weight, no appetite suppression at all. I can't tell I'm taking anything at all other than burping, acid reflux, and stomach pain through the night after eating."

• Ano...
• Taken for 6 months to 1 year
• July 17, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I have had good results with a 20% drop in weight in one year. Only occasional injection site redness. Occasional random stomachache not severe. Burping is significant. Occasional reflux. It helped with my hunger and feeling full quick. Gave me the strength to push away my plate and not gorge until it was all gone. Now my portions are much smaller. I feel my body adjusts to the dose rather quickly and then by the end of the week, I am starting to feel hungry again. This is the reason I scored it an 8."

• AC1...
• Taken for less than 1 month
• September 23, 2024

Tirzepatide for Type 2 Diabetes "I have been a type 2 diabetic for about 15 years. Worked hard to bring my A1c down with carb reduction and exercise. I track my 24-hour average glucose twice a day when I take my medications and track that number in a spreadsheet. I use a CGM. With the very first injection, I was able to detect a noticeable drop in my glucose numbers within 5 hours of the first injection. My 24-hour average glucose reading has dropped from 140 mg/dL to 110 mg/dL partway through the 2nd injection. I have not seen my glucose readings this good in years. My current tracking spreadsheet goes back to May of 2024. The doctor suggested this drug to see if weight loss induction might occur and help me become strictly diet controlled. During the first 2 weeks, I have been able to eliminate extended-release metformin from my medications. Some mild stomach pain and belching were initially present, but those have passed."

• Mat...
• Taken for 1 to 6 months
• March 4, 2025

Tirzepatide for Type 2 Diabetes "I am just getting back on after having to quit for hip joint replacement surgery. I am up to 7 mg now. My daily glucose level is going down. I’ve had some weight loss. But the side effects are discouraging. Excessive gas, burping, bloating, diarrhea, and fluttering inside my chest. These symptoms last 2 or 3 days after injection. I am going to continue injections in the hope the side effects get better."

• Joj...
• Taken for 6 months to 1 year
• February 3, 2025

Tirzepatide for Type 2 Diabetes "I started Mounjaro in March 2024 at 193 pounds and an A1C of 12.3. For almost 11 years as a type 1 diabetic. By July 2024, I was down to 153 pounds and an A1C of 7.75. I started off with the two, then went to the five, then to the seven, then to the 10. But after being on a 10, I started back developing an appetite, however, I exercised at least two hours per day faithfully in the gym. When I was on the number five, I had diarrhea a lot. When I made it to the 10, I just had a lot of belching, burping, saying that the 10 wasn’t doing much, I was still at like 150. I was bumped up to the number 12, and Lord have mercy on my soul. It almost took me out of here! I lost weight too fast. I got down to 116 pounds. I couldn’t. I didn’t have any desire to eat. I didn’t have any desire to drink. I would forget that I hadn’t been drinking anything. I would forget that I didn’t eat anything, and I’m still going to the gym every single day. It was until I dehydrated twice that I..."

• Joj...
• Taken for 6 months to 1 year
• February 3, 2025

Tirzepatide for Type 2 Diabetes "I started Mounjaro in March 2024 at 193 pounds and an A1C of 12.3. For almost 11 years as a type 1 diabetic. By July 2024, I was down to 153 pounds and an A1C of 7.75. I started off with the two, then went to the five, then to the seven, then to the 10. But after being on a 10, I started back developing an appetite, however, I exercised at least two hours per day faithfully in the gym. When I was on the number five, I had diarrhea a lot. When I made it to the 10, I just had a lot of belching, burping, saying that the 10 wasn’t doing much, I was still at like 150. I was bumped up to the number 12, and Lord have mercy on my soul. It almost took me out of here! I lost weight too fast. I got down to 116 pounds. I couldn’t. I didn’t have any desire to eat. I didn’t have any desire to drink. I would forget that I hadn’t been drinking anything. I would forget that I didn’t eat anything, and I’m still going to the gym every single day. It was until I dehydrated twice that I..."

• sir...
• Taken for less than 1 month
• January 5, 2023

Tirzepatide for Type 2 Diabetes "I experienced some nausea, had severe stomach pains at times, vomiting, indigestion, and terrible sulfur burps. The appetite suppression is amazing, as I felt like a normal person not feeling hungry all the time. After my 2nd shot and even worse side effects, I told my doctor I noticed my eyes had jaundice, so he told me to stop taking it. It did lower my blood sugar levels, and I'm so disappointed my body couldn't tolerate this medication, as it would have helped me lose weight."

• Luc...
• Taken for 1 to 6 months
• July 11, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "Love this medication and have lost 10kg in 6 weeks with a good diet and exercise. However, the side effects can be pretty intense. 2.5mg - sulfur burps, lethargy, flatulence, weight loss, decreased appetite, nausea. 5mg - sulfur burps, flatulence, abdominal distension, nausea, weight loss, chills, fever, headaches."

• Dav...
• Taken for less than 1 month
• July 13, 2024

Tirzepatide for Type 2 Diabetes "My doctor put me on Mounjaro to help control my newly diagnosed type two diabetes and A1c levels. I am overweight starting around 280 pounds when I began taking the medication. I’ve only been on the medication for two weeks and not due for my first round of blood tests for another month. Already in the short amount of time, I have lost 6 pounds. With the starting dose, I am having several of the side effects most commonly associated with this medication, to include belching, reflux, extreme feeling of fullness, flatulence, and the total lack of appetite. From what I read, the side effects should subside, and I’m glad I did research prior to going on this medication to fully understand how my body may react. I would not consider discontinuing the medication even though the early side effects are annoying, but I’m hoping that as time goes on, it will get better. I am most pleasantly surprised by the rapid weight loss."

• Lad...
• Taken for 6 months to 1 year
• April 25, 2023

Tirzepatide for Weight Loss (Obesity/Overweight) "I started taking Mounjaro on September 1, 2022. My starting weight was 192 lbs, I'm 38 years old and 5'3". By February 2023, I weighed in at 135 lbs. I experience severe nausea, sour stomach, sulfur burps, and constipation on every dose I was on. I was only able to go to 5 mg, as 7.5 mg about done me in. I went back to the 5 mg. I've always been active, worked out, etc., but after a few life events, I struggled to lose 10 lbs! This was a game changer for me. It quieted the food noise, the cravings, etc. I was able to eat just a few bites of whatever meal and then done. I didn't want to eat! My nighttime snacking is gone. I didn't even like the smell of McDonald's french fries. Now, my mom tried it also, but she never had any of the horrible symptoms, and the food noise quieted a little bit. She got up to 7.5 mg but couldn't get anything in stock for the 10 mg. She didn't lose the significant weight that I did and has now switched to Ozempic due to stock issues."

• Win...
• Taken for 1 to 6 months
• February 9, 2023

For Weight Loss (Obesity/Overweight) "I am a doctor and was hoping I could use this Mounjaro for my patients - thought I would try it first. Began with 2.5 mg for four weeks. Very bothersome reflux and was popping Rolaids. I lost 7 lbs in the first month. My doc increased me to 5 mg, and I did OK for the first two shots. On the third injection, I developed sulfur burps and diarrhea. After the fourth shot - I developed gastroparesis (stomach not emptying at all), profound nausea, dehydration, and I am very gassy. I have not been able to function for 5 days. Praying I am better tomorrow as I have a shift in the ED. Not sure about prescribing this based on my own experience."

• Tum...
• Taken for less than 1 month
• November 2, 2022

For Weight Loss (Obesity/Overweight) "I started the 2.5 Mounjaro injection prescribed by my doctor a week ago to help lose weight. I was happy that the injection was super easy and didn’t hurt at all. The first 2 days I felt great! I had zero appetite, even on the first day, and had to force myself to eat. By the 3rd day… it was a nightmare! I had nonstop diarrhea, the kind you get with colonoscopy prep stuff! I also experienced horrible, sulfur-like belching, especially when getting up in the morning, and had extreme pain in my lower back. Then, last night, I had extremely forceful vomiting, which is crazy because I don’t really have anything in my system! I still have the horrible diarrhea 7 days later, also pretty extreme fatigue, slight heartburn, and a nauseated feeling. I am just praying this stuff gets out of my system ASAP! I just wish someone could tell me how long before I feel better! I will not be using the rest of my Mounjaro injections after the experience I’ve had this first week."

• Cjl...
• Taken for 1 to 6 months
• June 14, 2023

Tirzepatide for Type 2 Diabetes "I was started on Mounjaro at the end of Jan 2023. My A1C was 10, and I am 41, about 5 ft 9 in. I weighed about 350 lbs. I had no energy, had sleep apnea, hurt all the time, and could not even walk without running out of breath. I was miserable. Finally, I talked to my doctor, and she decided to try me on this. After a little struggle getting insurance to cover it and get the med in stock at my pharmacy, I got going on this new journey. About 2 months in, I started having major diarrhea and vomiting. Had to take a break for a week and then started doing my injections in my thighs instead of my belly, and that has made it a lot more bearable. I do still get diarrhea and sulfur burps for 3, sometimes 4 days after my shot, but nothing major. Now my A1C is 6, my blood glucose averages 75, and I am weighing in at 270 lbs. I can walk now without running out of breath and without being in major pain. I have made other changes, such as watching what I eat, stopping drinking soda, and started trying to walk."

• Amy...
• Taken for 1 to 6 months
• October 21, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "I’ve lost about a pound per week, starting with the smallest dose and leveling up every month. I started at 187 pounds and am down to 172. Side effects: constipation, belching, and fatigue (probably due to not eating enough). I like the pens and got over my fear of the needle. Sometimes it leaves a red welt in my tummy, but not usually. The worst part about it is the cost. My insurance doesn’t cover it, even though I was obese, had pre-diabetes, and sleep apnea (which I didn’t have when I was thinner). Imagine how many health issues could be solved if people could use this to lose weight."

• Mag...
• Taken for less than 1 month
• May 6, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I am on my 4th week of 2.5 mg. Mild side effect of constipation, which I have managed with diet. Definitely reduced appetite, no desire to eat the usual chocolate, ice cream, or crisps, or late evening snacking. Then, a day after my 4th injection, I was, for the first time, suffering with wind, including the dreaded burps. Very little appetite. That was followed by a very bad bout of diarrhea, which saw me rushing to the loo all through the night. Settling down now after 24 hours. Not eaten today yet. Hoping this won't happen again, especially as I am due to increase dosage to 5 mg next week."