Mounjaro and Nausea: What Users Say (Page 3)

• Gre...
• Taken for 1 to 6 months
• February 28, 2023

For Type 2 Diabetes "I have been taking Mounjaro for 13 weeks. I am currently on the 7.5 mg dose. This medicine has changed my life! My A1C went from 12.9 to 6.5 in 12 weeks. My weight dropped 27 lbs, and my relationship with food has improved 100%. Side effects: slight nausea the day after I increased the dosage, decreased appetite, occasional need for a laxative to combat constipation."

• Mrs...
• Taken for less than 1 month
• February 21, 2023

For Type 2 Diabetes "I was on 2.5 dosages for several weeks. I felt a little nauseous but was losing weight and very happy. I was not waking up in the middle of the night feeling hungry. When I went to refill my next prescription, all the pharmacy had was 12.5 mg, so I agreed to try. Huge mistake. I have severe nausea, felt like I have the flu, can't stay awake, and body aches are ridiculous. I projectile vomited what looks like coffee grounds, I have awful sulfuric burps, and can't even keep down sips of water. I've missed 2 days of work thus far and have to have someone come to my house tomorrow to give me an IV because I'm too scared to drive. Not worth it at all."

• Enj...
• Taken for 6 months to 1 year
• February 8, 2025

For Type 2 Diabetes "I've been on Mounjaro for about 6 months now. I'm taking it for type 2 diabetes, and I needed to lose some weight also. At first, I had no side effects at all. However, in the past month, I've started going through quite a few. I'm currently on 7.5mg, and this is where my effects started. My appetite has gone from healthy to almost nonexistent, I'm always nauseous and now have low blood pressure. The good thing about it is that my A1c has drastically dropped from 11.9 to 6.5, which is really great. I'm getting blood glucose readings under 110, and before I started this medicine, I couldn't get my glucose under 280 on a good day. I'm currently seeing an endocrinologist and also a nutritionist who is awesome. My doctor says 7.5mg might be where I need to stay for a while, especially until my stomach adjusts to it. I wish it would hurry because I believe that Mounjaro is the best thing that was ever prescribed for me. I was previously on Bydurion (B-cise) for over 2 years, and it didn't help."

• S-L...
• Taken for 1 to 6 months
• November 6, 2022

For Type 2 Diabetes "I tried to leave a review, but for some reason, it wasn't posted, so I will try again. My doctor took me off of Mounjaro recently. I developed large welts about 24 hours after I injected the 75 doses and 10. My doctor fears I am developing an allergic reaction, so I am going back to the rival insulin alternative. (I had more side effects with the Ozempic: exhaustion, extreme nausea, and constipation, but hopefully, over time, they go away this time.) Too bad, because I really wanted to stay on Mounjaro. It should be noted that I really like Mounjaro very much. Well-controlled sugar, once I was on my maintenance dose of 10. For some reason, I gained five pounds while on Mounjaro, I never lost weight, where I lost about 15 pounds on the other mentioned insulin alternative. It seems that other patients on other review sites have this welt issue too. The issue should be reported not only to the doctor, but per the request of the manufacturer, please report to them as well."

• WVN...
• Taken for 1 to 6 months
• December 27, 2022

For Type 2 Diabetes "I started on the 2.5 dose in October, my doctor felt that the weight loss would help with my joint pain and lower my A1C. From day 1, I was extremely nauseous, had no desire to eat, had sulfur burps, and had constipation. I spoke with my doctor, who encouraged me to ride it out. On week four, I was stepped up to the 5 mg dosage. The doctor called in Zofran for stomach issues. On week six, I called her and said I could no longer function. During this time, I was so fatigued and was having heart palpitations and was barely able to walk 20 feet without being totally exhausted. I chalked it up to being so nauseous and not eating. Then my legs started to burn like I had walked up a steep hill and felt so sore and bruised I could barely sit. That week, I had my follow-up appointment with my doctor. I told her about my symptoms, and she said that rhabdomyolysis is not a side effect of Mounjaro. I was never dehydrated, but my CK levels were still 440 two weeks off the medication! Eight weeks later, and no improvement!"

• MAW...
• Taken for 1 to 6 months
• November 11, 2022

For Type 2 Diabetes "I started out on the 2.5 for 2 months and lost 15 lbs, and my A1C dropped from 6.7 to 6.0. Mild side effect symptoms of abdominal pain and nausea. I started the 5 mg and had explosive diarrhea and uncontrollable vomiting, with abdominal and back pain. My blood pressure dropped to 88/55. I had to stop taking the Mounjaro. After 3 weeks, I am starting to feel normal again. Sorry it didn’t work for me. It did curb the appetite."

• Hol...
• Taken for 1 to 6 months
• January 18, 2023

"For me, this is a miracle drug! I am perimenopausal and have gained belly fat and weight over the last two years. I started the Mounjaro 2.5 mg dose the first month and lost almost 3 pounds a week. I am sleeping better too, without the extra weight. The only side effects I have are small bouts of nausea here and there the first two days after my dose. Everyone I know taking the medication for weight loss who has had side effects has told me they are not eating properly or exercising. The recommendation was low sugar and no fried foods, so that is how I am eating. I have limited alcohol intake as well. I am now in my 6th week of the shots and was moved up to 5 mg on week five. I have the same side effects, a little bit of nausea here and there the first two days after the shot. I am now down 16 pounds. I only wanted to lose 20, so I am almost at my goal weight. My exercise consists of walking 2 miles around my neighborhood, yoga, and some pickleball. Eat well! Mounjaro is a miracle!"

• Mil...
• Taken for 1 to 6 months
• May 22, 2023

For Type 2 Diabetes "The meds did exactly what I expected. Lowered A1C, and I lost weight. The bad part is I was so sick on days 3-5 that it was awful. I couldn’t do my usual activities. No swimming for fear of losing control of bowels, and severe nausea. It worked great, but the side effects were extremely uncomfortable, I lost sleep from GERD. Disappointing for me."

• BMC...
• Taken for less than 1 month
• October 3, 2022

For Type 2 Diabetes "I'm only on my second week, but I've lost 7 pounds so far. It forces me to eat because if I don't, I feel sick, but when I eat, I get full super fast. So it's like it's forcing me to do good and not starve myself. I really like that. The first week I had slight nausea here and there and a couple of headaches. Also, a little indigestion. I do feel pretty tired. I've been eating a low-carb diet. I'm going to incorporate exercise at the end of this week. I can only imagine how much I have the potential to lose once I start exercising if I've lost 7 just by eating better. Overall, I am satisfied with this drug. I'm on the low dose right now."

• Not...
• Taken for less than 1 month
• October 23, 2022

For Type 2 Diabetes "I’m struggling to get below 154 lbs, and being 5’, that’s a lot of weight to carry, which induces back pain. Lost 20 lbs on Ozempic from the beginning of the year till June, have managed to gain back 5 lbs, which isn’t awful but still not at my goal weight. I just left the ER from getting a bolus of saline due to dehydration. I’m battling hypoglycemia. I took my first shot on Tuesday. Wednesday felt decent, but malaise was setting in. Thursday, I didn’t even realize I had not eaten all day and all night at work. Friday night, I tried to eat half of a sandwich and was completely nauseous. Tonight at work, after eating half a sandwich and a few green beans, I had terrible diarrhea and became so dizzy and nauseated I was forced to leave work, having someone else take over my patients. Just a word of advice: if you’re a busy person, this med may not be for you. I had side effects of fever, chills, nausea, diarrhea, fatigue, and muscle pain, and I was negative for flu, COVID, and strep. The doctor said to go back to Ozempic :( but I’ve lost 6 lbs already!"

• Anonymous
• Taken for 1 to 6 months
• March 4, 2025

For Type 2 Diabetes "This has been a miracle drug for me. I am a type 2 diabetic for over 20 years. I have diabetic neuropathy, so I struggle being on my feet. I was taking 100 units of insulin a day. I am 65, 5'11" and 219 lbs when I started taking Mounjaro. I started at 2.5 mg, I had zero side effects and no desire to eat. I went up to 5 mg, and I was severely nauseous for 3 days. The side effects went away and never came back. I am on 12.5 mg. I have been on Mounjaro for 5 months. I am 180 lbs, my A1C is 5.8. It has never been below 7 in 25 years. My cholesterol is perfect: 70 good, 70 bad. I take about 5 to 10 units of insulin daily. You cannot eat fatty foods, it makes you only reach for healthy foods. A couple of bites, and you’re full. I put zero effort to lose weight. I lost 39 lbs without trying. It was never about losing weight for me, it was being healthy. I now have normal blood pressure. This drug is a miracle for me."

• Lad...
• Taken for 1 to 6 months
• February 14, 2023

For Type 2 Diabetes "Rx for weight loss, extreme fatigue for the first 3 days after injection (I stayed in bed). I thought it was good for controlling binge eating. However, I eventually started to get so dizzy after standing up that I had to hold the counters and walls to get around for the first few minutes after standing. I also started to notice a thickness or knot in my throat after the first 2 months. I had to stop taking it because no amount of weight loss is worse than being a cancer patient or bedbound. The weight loss was extremely slow for me too. I went from being on no meds to relying daily on heartburn medicine, Miralax, Tylenol, and ginger chews for nausea. And the price was ridiculous. I would have rather bought some cosmetic surgery. I was on it 5 months: 2.5, then 0.5, finally 7.5 mg."

• Anonymous
• Taken for less than 1 month
• January 12, 2025

For Type 2 Diabetes "Mounjaro has helped me bring down my A1C. I'm only on a relatively low dose, but I am experiencing troubling side effects: stomach pain, indigestion, nausea, fatigue. I have the side effects mostly a day or two after the injection. I noticed a slight weight loss at first, but I think I gained the weight back somehow."

• Ano...
• Taken for 1 to 6 months
• April 3, 2025

For Weight Loss (Obesity/Overweight) "My experience with Mounjaro has been incredible. I started with 2.5 ml = 4/wk., 5 ml = 4/wk, 7.5 ml 4/wk (nausea with higher doses, no side effects). It's given me my life back. I have lost 15 kilos; I was 85 kilos, high cholesterol. I lost my appetite completely, eating only pears for breakfast, black coffee, steamed green veggies, and chicken. I have no dairy, takeout, or alcohol. Drinking a lot of water is essential, at least 3 liters or more per day. My body took four weeks to show any results; my body measurements changed first. I noticed in the 5th week, after a weekend, I had dropped 6 kg. My face became thinner, and someone said, 'You're shrinking.' I found it easier to drink fluids than eat food; it completely shut off my hunger. I had to make myself eat a savory biscuit. It was expensive! (No concession) Remember, everyone is different. I do have PHI, although they are ending the benefit due to the expense not being sustainable. I am strength training to gain muscle."

• Sha...
• Taken for 1 to 6 months
• June 13, 2023

For Weight Loss (Obesity/Overweight) "I have only lost 5 pounds in 2 months. It has severely decreased my appetite and occasionally caused nausea and stomach pain. I expected to lose more and more quickly than I have. Could not tolerate the severe nausea from Ozempic, so I switched to Mounjaro."

• Sar...
• Taken for less than 1 month
• August 15, 2024

For Weight Loss (Obesity/Overweight) "Female, 55, 183 lb, 5’6. Started on 2.5 three weeks ago. Was amazed how fast it started to work. Have lost 10 lb in three weeks. Cravings have gone. No longer thinking about food all the time. Junk food and sugar hold no appeal. Sleeping better. Only side effect is slight nausea day after the injection."

• Lif...
• Taken for less than 1 month
• August 9, 2024

For Weight Loss (Obesity/Overweight) "I was recommended weight loss pre-knee surgery and decided to try Mounjaro. I am a 55-year-old female, at least 12 kilos overweight. I have been using it for 3 weeks now (2.5 mg) and have lost 2 kg. There was no nausea, and I manage slight constipation with poached pears and yogurt or a prebiotic. I realized very quickly that I needed to eat smaller amounts more regularly as opposed to my previous habit of waiting until I was really hungry - I didn’t eat badly before, but my food portions were larger, and I regularly consumed alcohol. I tried a sip of champagne after 2 weeks of Mounjaro, and it tasted horrible. The combination of eating less, feeling satisfied, sleeping better, and weight loss has already changed my life for the better."

• Suf...
• Taken for 1 to 6 months
• December 31, 2022

For Type 2 Diabetes "My dose at 2.5 mg was tolerable. Minimal side effects. 5 mg more side effects with nausea, sour stomach, gas. 7.5 mg has been a disaster. Heartburn. Headaches, lethargy, tiredness, no appetite, and need to force food on myself. Low blood sugar on CGM Libre2. I can't eat enough to get myself back to 90. I keep pegging 70 because I can't eat and am sick to my stomach all the time. My sleep is interrupted, and I must lie down constantly. I feel like I want to sleep all the time. Weight has dropped from 250 to 233 lbs, but if I can't get out of bed, what's the point? I will talk to my doc about going back to 2.5 mg for the A1C control, but this drug needs work."

• Fer...
• Taken for less than 1 month
• July 27, 2024

For Weight Loss (Obesity/Overweight) "I had my three doses in three weeks, 5 mg each dose. I lost around 4-5 kg already. I never felt any nausea as I did with Ozempic or Saxenda. I had Ozempic and Saxenda for more than two years, and I didn't have any weight loss. With Mounjaro, I have already lost weight without any change in diet and activity (I had a good diet and activity before as well when I was taking Ozempic/Saxenda, but I didn’t have any weight loss). I feel very good, so I will continue the treatment."

• Lis...
• Taken for 6 months to 1 year
• March 28, 2025

For Weight Loss (Obesity/Overweight) "When I weighed 212 lbs at 5’1”, I was facing breast reduction surgery, A1c was over 8, I was on Metformin and on multiple antidepressants. My doctor started me on Mounjaro at increasing doses. Now, just about 8 months later, my A1c is 6, I no longer need Metformin and I currently weigh 135 lbs…I’ve lost a whopping 77 lbs! I feel great! The side effects have been… little to no appetite, nausea for two to three days after injection, constipation… all easily managed. Mounjaro has changed my life, and I would do it all over again!"

• bel...
• Taken for 6 months to 1 year
• May 11, 2023

For Type 2 Diabetes "A little bit of back story for the full benefit of transparency… I am a type 2 diabetic on an insulin pump, taking 2 Synjardy every morning in addition to my once-a-week injection. I was completely insulin resistant. Since starting the Mounjaro in September 2022 on the lowest dose, I have worked my way up to 10 mg. Now, a supply shortage kept me from getting my one-month supply twice in the last 7 months. When starting again, it did give me nausea and headaches, my doctor prescribed Zofran, and I took ibuprofen. When I started, I weighed 330 pounds and am currently down to 289 as of yesterday. The biggest benefit to me is that my pump has had to work less because the Mounjaro keeps my blood sugar steady at about 90. I am hoping as I continue to lose weight, I need less and less insulin, that is the doctor's goal. So while yes, there are side effects initially, they did not hang around for me, and if you can push through them, they do subside. I am 48 years old and have been diabetic since I was 23."

• MGS...
• Taken for 1 to 6 months
• February 5, 2025

"I initially took Mounjaro for a short while until my insurance refused to cover it. I had typical symptoms of nausea and reflux. I was switched to Ozempic, lost weight, and hit a plateau. Still felt nauseous on occasion. For the past month, I have been back on Mounjaro with no negative side effects. My appetite is less and I have lost a few pounds. I feel nauseous only slightly on occasion. The injection is sharp and hurts but is tolerable. I am grateful for it. My husband has been taking Mounjaro for several months, has been experiencing mild side effects, and continues to lose weight. He pays about $1,000/month out of pocket because insurance doesn't cover it."

• MGS...
• Taken for 1 to 6 months
• February 5, 2025

"I initially took Mounjaro for a short while until my insurance refused to cover it. I had typical symptoms of nausea and reflux. I was switched to Ozempic, lost weight, and hit a plateau. Still felt nauseous on occasion. For the past month, I have been back on Mounjaro with no negative side effects. My appetite is less and I have lost a few pounds. I feel nauseous only slightly on occasion. The injection is sharp and hurts but is tolerable. I am grateful for it. My husband has been taking Mounjaro for several months, has been experiencing mild side effects, and continues to lose weight. He pays about $1,000/month out of pocket because insurance doesn't cover it."

• sve...
• Taken for 1 to 6 months
• March 1, 2023

For Weight Loss (Obesity/Overweight) "I have been taking Mounjaro for 4 months and have lost 20 lbs. I am currently taking 7.5 mg, and since I have been on this dosage, I have experienced nausea, stomach cramps, heartburn, and fatigue. I plan on lowering my dosage to maintain."

• del...
• Taken for 1 to 6 months
• January 25, 2023

For Type 2 Diabetes "What a game changer this medicine is for weight loss... unfortunately, at $500/month after coupon, it is just cost prohibitive. The first month my insurance did cover, and what I noticed were immediate impacts on appetite, no urge to snack, no anxiety eating, and no hunger pangs. I have about 60 pounds to lose, and lost 5.5 pounds that first month. I did not have any side effects, except once I ate something sweet, I had a little nausea. Lesson: don't eat sweets :) I really wish my insurance would cover this, because I've never experienced anything like it."