Skip to main content

Tirzepatide for Type 2 Diabetes User Reviews (Page 4)

Brand names: Mounjaro, Zepbound

Reviews for Tirzepatide

Commonly mentioned side effects
  • Mou...
  • Taken for 1 to 6 months
  • January 27, 2025

"I have been on Mounjaro for 7 weeks. The first 4 weeks the dosage was 2.5, and the last 3 weeks it was 5. I love Mounjaro! It takes away my food obsessions and sugar cravings. It lets me focus on life rather than on food. I did get a few minor incidents of diarrhea and an occasional minor feeling of nausea, but they were nothing serious. Mounjaro has helped me lose 15 pounds in 7 weeks and brought my blood sugar from 220 to 120. I wish it were cheaper, but it has been worth it for me."

10 / 10
Was this helpful?YesNo
4 Report
  • Mj-...
  • Taken for 6 months to 1 year
  • July 24, 2024

"I weighed in at 265 on September 27, 2023. My first month, I lost nearly 30 lbs, two another 20 lbs. I’ve lost nearly 80 lbs. I’ve gone from a size 22/24 to a size 12. From a size 2x tops to a medium/large. In September, I was injecting 50 units of Lantus AM and PM, and 15 units of Humalog 3x daily. My diabetes was still out of control. My mother and father both were insulin-dependent. My mother lost her kidneys and my father lost his legs, one joint at a time. I am so thankful I gave Mounjaro a chance. From my first injection of 2.5 on 9/27/23, I have not needed a drop of insulin nor any other diabetic medication. I also have the energy (sun up to sun down) of a 4-year-old! This medicine has changed my life! Thank you, Mounjaro!!! I never thought I’d say this, but I’m still losing, very slowly. I’m wondering where it will stop. I’m backing the dose down Thursday - I want to get to 2.5 and stay there. I’m on 7.5 now. Don’t give up. With Mounjaro, you can do this!"

10 / 10
Was this helpful?YesNo
9 Report
  • peb...
  • Taken for 1 to 6 months
  • February 26, 2023

"Started this 7 weeks ago and have one more injection. The first set was at 2.5 mg from the gynecologist. Within the first week, I lost 5 pounds and by week 5 I saw a huge difference! I went from a 22 waist to a true size 18 and still shrinking. I was having trouble catching my breath before I started this. I had a couple of pains in my stomach, similar to gas pains like clockwork, the day after the injection. But it was bearable. Sometimes I get a smelly burp issue. But now I have lost 20 pounds at week 7 and feel amazing. Please do yourself a favor and take fiber daily, this medicine will get you constipated."

10 / 10
Was this helpful?YesNo
19 Report

Frequently asked questions

  • Jud...
  • Taken for 1 to 6 months
  • January 22, 2025

"I started Mounjaro 8 weeks ago. I’m 69 years old with T2D and weighing 234 lbs. I now weigh 214. I start on 7.5 this weekend. I have had light nausea and light constipation, and the lovely burps, but other than that, all is good. I eat better, no hunger 24/7, and I feel so much better. No more metformin. Yay!!!!"

10 / 10
Was this helpful?YesNo
4 Report
  • 8LL...
  • Taken for 1 to 6 months
  • June 9, 2023

"Started medication in early March. One dose weekly for 6 weeks, till I quit. Severe nausea that would last for 5 days after each shot. It does eliminate your desire to eat, but I gained 11 pounds during the 6-week period. Also, I now have an irregular heartbeat and shortness of breath from this. I've been off the medication since mid-April. It is now 6/9/23, and I am still having problems, and upcoming heart tests scheduled."

1 / 10
Was this helpful?YesNo
18 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Kel...
  • Taken for 1 to 2 years
  • February 20, 2025

"For the first time in my life, I am not hungry all the time. I can walk by a bakery and not have to go inside. I can eat one cookie and be satisfied. The only downside is the lack of motivation to do anything. There have been no sexual side effects except for lack of desire."

9 / 10
Was this helpful?YesNo
3 Report
  • Col...
  • Taken for 1 to 6 months
  • February 19, 2025

"I have been on Mounjaro since Nov 2024. Just turned 60, and I have lost 25 lbs. I am a type 2 diabetic plus suffering from other health problems. Didn’t have too bad of side effects like most people have commented. Started 10 mg this week. I started at about 199 lbs, now weigh in at 175. My goal is 155 to 160. Lab work in another week with yearly physical. Hoping all numbers go down with those too!!"

10 / 10
Was this helpful?YesNo
3 Report

More FAQ

  • Pat...
  • Taken for 1 to 2 years
  • February 17, 2025

"I have been on Mounjaro for about 1 1/2 years. I have lost 135 lbs and down to 170! Never had any side effects. My A1C was a 7.8, and only 3 months after taking it, I was a 5.7!! Now I am at 5.1! In my case, I have always been addicted to food, and all my life never could stop thinking about it. For the first time in my life, I can eat lunch like a normal person and stop eating and not obsess over eating! I think it has changed my brain like no other therapy has."

10 / 10
Was this helpful?YesNo
3 Report
  • Son...
  • Taken for 1 to 6 months
  • March 19, 2025

"Started on 2.5 mg in December and have titrated up every 4 weeks to 12.5 mg currently. So far I have been losing 2-3 lbs a week and have lost 34 lb, and up until now I haven't really noted any serious side effects other than occasional constipation and slight nausea if I don't eat something small every few hours, or if I eat something really fatty. The last two titrations I have noticed some extreme fatigue and being cold on the first day after my shot, but then it usually starts to go away on the 2nd day and I feel better. I have also noticed that if I try to push through the tiredness and try exercising, I usually feel better. I have tried to stick to a 1200-1500 calorie diet and do eat a lot more fruits and veggies, and I feel better than I have in a long time. Overall, it’s been a good experience and I’m super excited to see how much more weight I can lose."

9 / 10
Was this helpful?YesNo
2 Report
  • mou...
  • Taken for less than 1 month
  • June 1, 2023

"My husband suffered from severe nausea, mostly at night, but also from loss of appetite, constipation, and increased fatigue. He could not even get out of bed after one injection. He will not take a second dose."

1 / 10
Was this helpful?YesNo
18 Report
  • 54...
  • Taken for 2 to 5 years
  • April 9, 2024

"Mounjaro has been a life changer for me. I currently take 12.5 mg and have been on it for about two years. I have lost 141 lbs and I now weigh 115 lbs, size 22 to size 0-2. I was able to get off all other diabetes medications. I have severe insomnia on the night I take my shot whether I take it at night or in the morning. I take my shot in my thigh because my side effects are less when I inject it there. I steer away from carbs and sugar to avoid causing stomach issues. I do get tired the first few days after my shot but it could be because I don’t sleep well the night I take my injection."

10 / 10
Was this helpful?YesNo
10 Report
  • Gre...
  • Taken for 1 to 6 months
  • February 28, 2023

"I have been taking Mounjaro for 13 weeks. I am currently on the 7.5 mg dose. This medicine has changed my life! My A1C went from 12.9 to 6.5 in 12 weeks. My weight dropped 27 lbs, and my relationship with food has improved 100%. Side effects: slight nausea the day after I increased the dosage, decreased appetite, occasional need for a laxative to combat constipation."

10 / 10
Was this helpful?YesNo
17 Report
  • Rod...
  • Taken for less than 1 month
  • May 22, 2024

"Wonderful. No side effects. Have appetite suppression, which is good for weight loss. However, I do not feel I am starving at all. Have lost 6.8 lbs. in the first two weeks. Taking 2.5 mg. Walking 45 minutes on treadmill early each day and do not really have the desire to eat junk food. Eat well, especially breakfast which was the same I had been doing, but the same after I had heart surgery last year. I am increasing to 5mg. after this week and I will see how it goes. No side effects at all as far as I can tell."

10 / 10
Was this helpful?YesNo
9 Report
  • Mrs...
  • Taken for less than 1 month
  • February 21, 2023

"I was on 2.5 dosages for several weeks. I felt a little nauseous but was losing weight and very happy. I was not waking up in the middle of the night feeling hungry. When I went to refill my next prescription, all the pharmacy had was 12.5 mg, so I agreed to try. Huge mistake. I have severe nausea, felt like I have the flu, can't stay awake, and body aches are ridiculous. I projectile vomited what looks like coffee grounds, I have awful sulfuric burps, and can't even keep down sips of water. I've missed 2 days of work thus far and have to have someone come to my house tomorrow to give me an IV because I'm too scared to drive. Not worth it at all."

1 / 10
Was this helpful?YesNo
25 Report
  • Anonymous
  • Taken for 1 to 6 months
  • February 9, 2025

"Once I started taking this product, I was able to get off Metformin and insulin. My sugar was never high during the time on Mounjaro, and I lost 30 pounds and felt great! There are side effects with a few stomach issues, but they are short-lived."

8 / 10
Was this helpful?YesNo
3 Report
  • Enj...
  • Taken for 6 months to 1 year
  • February 8, 2025

"I've been on Mounjaro for about 6 months now. I'm taking it for type 2 diabetes, and I needed to lose some weight also. At first, I had no side effects at all. However, in the past month, I've started going through quite a few. I'm currently on 7.5mg, and this is where my effects started. My appetite has gone from healthy to almost nonexistent, I'm always nauseous and now have low blood pressure. The good thing about it is that my A1c has drastically dropped from 11.9 to 6.5, which is really great. I'm getting blood glucose readings under 110, and before I started this medicine, I couldn't get my glucose under 280 on a good day. I'm currently seeing an endocrinologist and also a nutritionist who is awesome. My doctor says 7.5mg might be where I need to stay for a while, especially until my stomach adjusts to it. I wish it would hurry because I believe that Mounjaro is the best thing that was ever prescribed for me. I was previously on Bydurion (B-cise) for over 2 years, and it didn't help."

8 / 10
Was this helpful?YesNo
3 Report
  • S-L...
  • Taken for 1 to 6 months
  • November 6, 2022

"I tried to leave a review, but for some reason, it wasn't posted, so I will try again. My doctor took me off of Mounjaro recently. I developed large welts about 24 hours after I injected the 75 doses and 10. My doctor fears I am developing an allergic reaction, so I am going back to the rival insulin alternative. (I had more side effects with the Ozempic: exhaustion, extreme nausea, and constipation, but hopefully, over time, they go away this time.) Too bad, because I really wanted to stay on Mounjaro. It should be noted that I really like Mounjaro very much. Well-controlled sugar, once I was on my maintenance dose of 10. For some reason, I gained five pounds while on Mounjaro, I never lost weight, where I lost about 15 pounds on the other mentioned insulin alternative. It seems that other patients on other review sites have this welt issue too. The issue should be reported not only to the doctor, but per the request of the manufacturer, please report to them as well."

6 / 10
Was this helpful?YesNo
20 Report
  • WE...
  • Taken for less than 1 month
  • November 8, 2022

"Went to the doctor and asked for something to help lose weight. He prescribed this medication. Day 1 and 2... nothing. Day 3 woke up with horrible heartburn and sour sulfur burps and facts and was constipated. By day 3 evening, I no longer had constipation but just the opposite... diarrhea! And not just any kind, it was like yellow water and very acidic. It hurt! Had horrible gas and belching all day Saturday, and Sunday couldn't hardly leave the bathroom to go buy Imodium. Imodium helped with that, but the gas is now trapped, and my stomach hurts badly, and I am full of gas with bad heartburn and belching. I saw a correlation between fatty foods and severe side effects of this product. But unless you're a vegan, you eat fat, and that's a major problem with this product. It is now Monday night, and I cannot seem to get my work done, I hurt so badly. I will never take this product again, and I cannot in good conscience recommend it with all the terrible side effects. Shame on Mounjaro!"

1 / 10
Was this helpful?YesNo
29 Report
  • WVN...
  • Taken for 1 to 6 months
  • December 27, 2022

"I started on the 2.5 dose in October, my doctor felt that the weight loss would help with my joint pain and lower my A1C. From day 1, I was extremely nauseous, had no desire to eat, had sulfur burps, and had constipation. I spoke with my doctor, who encouraged me to ride it out. On week four, I was stepped up to the 5 mg dosage. The doctor called in Zofran for stomach issues. On week six, I called her and said I could no longer function. During this time, I was so fatigued and was having heart palpitations and was barely able to walk 20 feet without being totally exhausted. I chalked it up to being so nauseous and not eating. Then my legs started to burn like I had walked up a steep hill and felt so sore and bruised I could barely sit. That week, I had my follow-up appointment with my doctor. I told her about my symptoms, and she said that rhabdomyolysis is not a side effect of Mounjaro. I was never dehydrated, but my CK levels were still 440 two weeks off the medication! Eight weeks later, and no improvement!"

1 / 10
Was this helpful?YesNo
17 Report
  • Gra...
  • Taken for 1 to 2 years
  • March 5, 2024

"The drug alone is not the end-all-be-all, it takes lifestyle changes as well. The medicine helps curb my appetite and lowers my glucose by slowing down digestion, but making better eating choices, having smaller portions, etc., are just as important. Mounjaro has definitely had a positive impact, but there are some side effects. If you eat too much, you are going to feel it later and it's miserable. The medicine is almost like a coach to help show you the door, you have to walk through the door and make the lifestyle changes on your own."

10 / 10
Was this helpful?YesNo
10 Report
  • Fat...
  • Taken for 6 months to 1 year
  • February 6, 2025

"My experience has been very good. I took drastic steps to change eating habits, cutting carbs where possible. Rather than eating chips at home, I go through 6 lbs of carrots per week. I divorced French fries. Aside from that, I still eat what I want when dining out. Dropped from 330 lbs to 262 lbs in 8 months. No side effects aside from constipation - daily fiber and stool softeners make that manageable. I feel that part of the weight loss was simply the change in diet, but the Mounjaro certainly helped. I'm on the 2.5 dosage."

9 / 10
Was this helpful?YesNo
3 Report
  • MAW...
  • Taken for 1 to 6 months
  • November 11, 2022

"I started out on the 2.5 for 2 months and lost 15 lbs, and my A1C dropped from 6.7 to 6.0. Mild side effect symptoms of abdominal pain and nausea. I started the 5 mg and had explosive diarrhea and uncontrollable vomiting, with abdominal and back pain. My blood pressure dropped to 88/55. I had to stop taking the Mounjaro. After 3 weeks, I am starting to feel normal again. Sorry it didn’t work for me. It did curb the appetite."

3 / 10
Was this helpful?YesNo
17 Report
  • I...
  • Taken for 6 months to 1 year
  • February 15, 2024

"I have been on Mounjaro since March 2023, it is now February 2024. When my doctor suggested Mounjaro to me, I was at a point in my life where I didn't think it could get much worse. My A1C was off the charts, I was severely obese at 280 pounds, and I was scheduling my 6th surgery in 7 months! Now, almost a year later, my diabetes is gone! I am 100 pounds down to 180 and no more surgeries in my foreseeable future! Game changer!"

10 / 10
Was this helpful?YesNo
10 Report
  • Duc...
  • Taken for 1 to 6 months
  • October 16, 2022

"I was using Ozempic, but Dr. switched to Mounjaro. It has been terrible! I lost a lot of weight on Ozempic but gained some back since being on Mounjaro. Also, my blood sugar rose 10-15 points since switching! I have had numerous side effects, mainly headaches and constipation. When giving it, it always seems to leak back out of my skin, and I've tried stomach, arms, thighs- all the same! I am not happy."

1 / 10
Was this helpful?YesNo
17 Report
  • Ton...
  • Taken for 1 to 2 years
  • January 31, 2025

"I started at a very heavy weight, 260. I am now 188. The one thing I hate is the hair loss! That wasn’t a side effect. I still inject it, but I wish Lilly would explain how to not lose my hair. I’ve taken it for about two years, and I may take a break soon to see what happens. My A1C is great."

10 / 10
Was this helpful?YesNo
3 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.