Tirzepatide for Type 2 Diabetes User Reviews (Page 4)
Brand names: Mounjaro, Zepbound
Reviews for Tirzepatide
- peb...
- Taken for 1 to 6 months
- February 26, 2023
"Started this 7 weeks ago and have one more injection. The first set was at 2.5 mg from the gynecologist. Within the first week, I lost 5 pounds and by week 5 I saw a huge difference! I went from a 22 waist to a true size 18 and still shrinking. I was having trouble catching my breath before I started this. I had a couple of pains in my stomach, similar to gas pains like clockwork, the day after the injection. But it was bearable. Sometimes I get a smelly burp issue. But now I have lost 20 pounds at week 7 and feel amazing. Please do yourself a favor and take fiber daily, this medicine will get you constipated."
- abq...
- Taken for 1 to 6 months
- February 11, 2025
"Blood sugar is similar levels to other similar drugs so far. Like the auto injector and very easy to use. I hate the plastic waste and disposal volume. Appetite control is good. Feel full most times, and when I eat, I get full quickly - which controls eating amount. Not at maximum dosage currently. Waiting on healthcare practitioner for any more changes..."
Frequently asked questions
- Zepbound vs Mounjaro: Comparison Guide for Weight Loss and Diabetes Treatment
- Why am I not losing weight on Mounjaro?
- Which GLP-1 drug is best for weight loss?
- Tirzepatide vs semaglutide: How do they compare?
- The...
- Taken for 1 to 2 years
- December 24, 2024
"I tried Wegovy and Ozempic with no results. My endocrinologist switched me to Mounjaro, and I have had fantastic success. In 18 months, I have lost 100 pounds. My A1c is normal. I’ve been off insulin for 5 months, and I feel healthier and more energetic. The only side effects I have experienced are usually the day after I’ve taken my shot, I have an upset stomach, and I am not hungry at all. Best of all, I can shop in normal sizes now instead of plus."
- WE...
- Taken for less than 1 month
- November 8, 2022
"Went to the doctor and asked for something to help lose weight. He prescribed this medication. Day 1 and 2... nothing. Day 3 woke up with horrible heartburn and sour sulfur burps and facts and was constipated. By day 3 evening, I no longer had constipation but just the opposite... diarrhea! And not just any kind, it was like yellow water and very acidic. It hurt! Had horrible gas and belching all day Saturday, and Sunday couldn't hardly leave the bathroom to go buy Imodium. Imodium helped with that, but the gas is now trapped, and my stomach hurts badly, and I am full of gas with bad heartburn and belching. I saw a correlation between fatty foods and severe side effects of this product. But unless you're a vegan, you eat fat, and that's a major problem with this product. It is now Monday night, and I cannot seem to get my work done, I hurt so badly. I will never take this product again, and I cannot in good conscience recommend it with all the terrible side effects. Shame on Mounjaro!"
- mou...
- Taken for less than 1 month
- June 1, 2023
"My husband suffered from severe nausea, mostly at night, but also from loss of appetite, constipation, and increased fatigue. He could not even get out of bed after one injection. He will not take a second dose."
- Fre...
- Taken for 1 to 6 months
- August 26, 2025
"Mounjaro has certainly reduced my A1C. My DR prescribed 2.5 for one month, then 5.0 for one month and 7.5 after that. Unfortunately, I started vomiting really bad, and I stopped for two weeks. I committed to 5.0 after that, but the vomiting has continued about two days after my shot. I have to stop the Mounjaro, and I know my A1C will go back up. I hope that a new version will be developed to eliminate the vomiting, as the drug for type II diabetes is a godsend."
More FAQ
- Mounjaro side effects to be aware of
- How much is Zepbound with or without insurance?
- How does Mounjaro Work for Weight Loss?
- Can you get tirzepatide from a compounding pharmacy?
- Gre...
- Taken for 1 to 6 months
- February 28, 2023
"I have been taking Mounjaro for 13 weeks. I am currently on the 7.5 mg dose. This medicine has changed my life! My A1C went from 12.9 to 6.5 in 12 weeks. My weight dropped 27 lbs, and my relationship with food has improved 100%. Side effects: slight nausea the day after I increased the dosage, decreased appetite, occasional need for a laxative to combat constipation."
- Mrs...
- Taken for less than 1 month
- February 21, 2023
"I was on 2.5 dosages for several weeks. I felt a little nauseous but was losing weight and very happy. I was not waking up in the middle of the night feeling hungry. When I went to refill my next prescription, all the pharmacy had was 12.5 mg, so I agreed to try. Huge mistake. I have severe nausea, felt like I have the flu, can't stay awake, and body aches are ridiculous. I projectile vomited what looks like coffee grounds, I have awful sulfuric burps, and can't even keep down sips of water. I've missed 2 days of work thus far and have to have someone come to my house tomorrow to give me an IV because I'm too scared to drive. Not worth it at all."
- MAW...
- Taken for 1 to 6 months
- November 11, 2022
"I started out on the 2.5 for 2 months and lost 15 lbs, and my A1C dropped from 6.7 to 6.0. Mild side effect symptoms of abdominal pain and nausea. I started the 5 mg and had explosive diarrhea and uncontrollable vomiting, with abdominal and back pain. My blood pressure dropped to 88/55. I had to stop taking the Mounjaro. After 3 weeks, I am starting to feel normal again. Sorry it didn’t work for me. It did curb the appetite."
- WVN...
- Taken for 1 to 6 months
- December 27, 2022
"I started on the 2.5 dose in October, my doctor felt that the weight loss would help with my joint pain and lower my A1C. From day 1, I was extremely nauseous, had no desire to eat, had sulfur burps, and had constipation. I spoke with my doctor, who encouraged me to ride it out. On week four, I was stepped up to the 5 mg dosage. The doctor called in Zofran for stomach issues. On week six, I called her and said I could no longer function. During this time, I was so fatigued and was having heart palpitations and was barely able to walk 20 feet without being totally exhausted. I chalked it up to being so nauseous and not eating. Then my legs started to burn like I had walked up a steep hill and felt so sore and bruised I could barely sit. That week, I had my follow-up appointment with my doctor. I told her about my symptoms, and she said that rhabdomyolysis is not a side effect of Mounjaro. I was never dehydrated, but my CK levels were still 440 two weeks off the medication! Eight weeks later, and no improvement!"
- she...
- Taken for 1 to 6 months
- January 12, 2025
"I actually called my Dr. and thanked her for saving my life! I've dropped 33 lbs in 3 months. I no longer have swollen feet, my A1C has dropped a full point. Also, I no longer need Januvia or glipizide. It's amazing what processed sugar does to your body. I don't have the sugar craving anymore. My blood sugar is perfect every morning."
- Lin...
- Taken for 1 to 6 months
- November 10, 2024
"I’ve been taking 2.5 ml for 4 weeks and had few side effects apart from zero appetite, a little nausea, and a migraine (think the migraine was due to not eating). Now, week 5, increased to 5 ml and a different story: quite a lot of nausea, diarrhea, headache, and tiredness. Also again, total lack of appetite. Fortunately, these side effects more or less calmed down 2 or 3 days after taking the dose. I’m hoping it’s a temporary thing when you take a new dose - I can live with that."
- Pru...
- Taken for 1 to 6 months
- January 7, 2025
"I took Mounjaro for 5 weeks, had to stop taking it due to acid reflux and severe indigestion, been off it for 3 full weeks and still having severe stomach problems. Eating very small meals, drinking a gallon of water every day, don’t lay down after eating, blah, blah. Now I have to go see a stomach specialist. I do not recommend taking this medication."
- Jam...
- Taken for 1 to 2 years
- August 23, 2025
"Works well for daily glucose control and weight management. I find it really curbs my overactive appetite and allows me to lose weight consistently but slowly, which is fine for me. No side effects that I’m aware of. I’m on 12.5 now."
- Duc...
- Taken for 1 to 6 months
- October 16, 2022
"I was using Ozempic, but Dr. switched to Mounjaro. It has been terrible! I lost a lot of weight on Ozempic but gained some back since being on Mounjaro. Also, my blood sugar rose 10-15 points since switching! I have had numerous side effects, mainly headaches and constipation. When giving it, it always seems to leak back out of my skin, and I've tried stomach, arms, thighs- all the same! I am not happy."
- 54...
- Taken for 2 to 5 years
- April 9, 2024
"Mounjaro has been a life changer for me. I currently take 12.5 mg and have been on it for about two years. I have lost 141 lbs and I now weigh 115 lbs, size 22 to size 0-2. I was able to get off all other diabetes medications. I have severe insomnia on the night I take my shot whether I take it at night or in the morning. I take my shot in my thigh because my side effects are less when I inject it there. I steer away from carbs and sugar to avoid causing stomach issues. I do get tired the first few days after my shot but it could be because I don’t sleep well the night I take my injection."
- Not...
- Taken for less than 1 month
- October 23, 2022
"I’m struggling to get below 154 lbs, and being 5’, that’s a lot of weight to carry, which induces back pain. Lost 20 lbs on Ozempic from the beginning of the year till June, have managed to gain back 5 lbs, which isn’t awful but still not at my goal weight. I just left the ER from getting a bolus of saline due to dehydration. I’m battling hypoglycemia. I took my first shot on Tuesday. Wednesday felt decent, but malaise was setting in. Thursday, I didn’t even realize I had not eaten all day and all night at work. Friday night, I tried to eat half of a sandwich and was completely nauseous. Tonight at work, after eating half a sandwich and a few green beans, I had terrible diarrhea and became so dizzy and nauseated I was forced to leave work, having someone else take over my patients. Just a word of advice: if you’re a busy person, this med may not be for you. I had side effects of fever, chills, nausea, diarrhea, fatigue, and muscle pain, and I was negative for flu, COVID, and strep. The doctor said to go back to Ozempic :( but I’ve lost 6 lbs already!"
- Fin...
- Taken for 1 to 6 months
- October 19, 2022
"Mounjaro works! My blood sugar was off the charts. The first week I started taking Mounjaro, my blood sugar was within normal limits. I don’t remember the last time it was normal. Very little side effects the first week. No side effects second week to date. Taking my 8th dose tonight. And lost 7 pounds."
- BMC...
- Taken for less than 1 month
- October 3, 2022
"I'm only on my second week, but I've lost 7 pounds so far. It forces me to eat because if I don't, I feel sick, but when I eat, I get full super fast. So it's like it's forcing me to do good and not starve myself. I really like that. The first week I had slight nausea here and there and a couple of headaches. Also, a little indigestion. I do feel pretty tired. I've been eating a low-carb diet. I'm going to incorporate exercise at the end of this week. I can only imagine how much I have the potential to lose once I start exercising if I've lost 7 just by eating better. Overall, I am satisfied with this drug. I'm on the low dose right now."
- Mil...
- Taken for 1 to 6 months
- May 22, 2023
"The meds did exactly what I expected. Lowered A1C, and I lost weight. The bad part is I was so sick on days 3-5 that it was awful. I couldn’t do my usual activities. No swimming for fear of losing control of bowels, and severe nausea. It worked great, but the side effects were extremely uncomfortable, I lost sleep from GERD. Disappointing for me."
- MJs...
- Taken for 1 to 6 months
- February 17, 2023
"3.5 months from 2.5 mg to 5.0 mg. Even before starting 7.5 mg, my experience has been positive. Less stressful, as if my cortisol levels are low. No desire to drink alcoholic beverages. Appetite suppressed, loss of inches before any noticeable weight loss. Slow loss of excess weight. PCOS symptoms have mostly disappeared, however, when refills were not available, all symptoms almost immediately presented again, including desire to snack. Constipation is noticeable at 5.0 mg. Starting 7.5 mg now. 22 lb of excess weight lost after 3.5 months of use."
- Rod...
- Taken for less than 1 month
- May 22, 2024
"Wonderful. No side effects. Have appetite suppression, which is good for weight loss. However, I do not feel I am starving at all. Have lost 6.8 lbs. in the first two weeks. Taking 2.5 mg. Walking 45 minutes on treadmill early each day and do not really have the desire to eat junk food. Eat well, especially breakfast which was the same I had been doing, but the same after I had heart surgery last year. I am increasing to 5mg. after this week and I will see how it goes. No side effects at all as far as I can tell."
- Ama...
- Taken for less than 1 month
- November 13, 2022
"My doctor put me on Mounjaro for potential type 2 diabetes. Just after one month of taking it, I have been living through the 3rd week of taking 2.5g. For the past 2 weeks, dizziness, severe shaking and trembling, my throat swelling so much that I am having trouble swallowing and having a sip of water. I have stopped taking it and cannot wait for this mess to get out of my system and be normal again. I did not have any of these issues prior. I did lose 12 lbs, but it's definitely not worth choking."
- Gra...
- Taken for 1 to 2 years
- March 5, 2024
"The drug alone is not the end-all-be-all, it takes lifestyle changes as well. The medicine helps curb my appetite and lowers my glucose by slowing down digestion, but making better eating choices, having smaller portions, etc., are just as important. Mounjaro has definitely had a positive impact, but there are some side effects. If you eat too much, you are going to feel it later and it's miserable. The medicine is almost like a coach to help show you the door, you have to walk through the door and make the lifestyle changes on your own."
See also:
Learn more about Type 2 Diabetes
- Diabetes Medications and Alcohol Interactions
- FDA-Approved Weight Loss Drugs: Can They Help You?
- OneTouch Blood Glucose Meters
- Side Effects of Weight Loss Drugs
- Top 10 Diabetes Treatments You May Have Missed
- Which Drugs Cause Weight Gain?
Care guides
- Diabetes and your Skin
- Diabetic Gastroparesis
- Diabetic Hyperglycemia
- Diabetic Kidney Disease
- Diabetic Neuropathy
- How to Draw Up Insulin
- Hypoglycemia in a Person with Diabetes
Medicine.com guides (external)
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"I started using Mounjaro at 2.4 mg, worked great, no side effects. After the doctor increased it to 5 mg, I developed severe stomach pain, both upper and lower. I couldn't tolerate the pain. I was taking oxycodone. Tried to live with the pain, but I couldn't take it anymore, so I stopped. Taking this medication, be very careful with what you're doing. My blood pressure was very high. My doctor was out of reach, so I went to another doctor. He prescribed a test on my pancreas, and the test came out bad. I was informed to stop this medication and take another test in six months. They didn't tell me what's wrong, they just told me to stop this medication and that I have to take another test in 6 months. It's very serious."