Tirzepatide for Type 2 Diabetes User Reviews (Page 3)
Brand names: Mounjaro, Zepbound
Reviews for Tirzepatide
- Pru...
- Taken for 1 to 6 months
- January 7, 2025
"I took Mounjaro for 5 weeks, had to stop taking it due to acid reflux and severe indigestion, been off it for 3 full weeks and still having severe stomach problems. Eating very small meals, drinking a gallon of water every day, don’t lay down after eating, blah, blah. Now I have to go see a stomach specialist. I do not recommend taking this medication."
- DWA...
- Taken for 1 to 6 months
- October 14, 2024
"My doc insisted that I give this med a shot. My A1c was just over 7, but I am 59, 6’, and hit my heaviest weight in my life of 283.3 lbs on July 3, 2024. I started taking the 2.5 mg on July 12, 2024, and 3 months later, now at the 7.5 mg dose, I have lost 33 lbs! I do get acid reflux if I overeat (I still love food) and constipation if I don’t drink enough water, but otherwise, every Monday I give myself a shot - tired for a day and then back to normal. I had tried in the past to shed a few pounds, but nothing ever worked, so I had learned to live with it. This is some magic potion in the form of science that is giving me my life back. My goal is 225 lbs by the end of 2024 and 200 lbs in 2025. Biggest problem is my pants no longer fit!"
Frequently asked questions
- Zepbound Vs Mounjaro: Complete Comparison Guide for Weight Loss and Diabetes Treatment
- Why am I not losing weight on Mounjaro?
- How do Ozempic, Mounjaro, Wegovy, Zepbound compare for weight loss?
- Tirzepatide vs semaglutide: How do they compare?
- Jav...
- Taken for less than 1 month
- December 14, 2022
"I had previously been on Trulicity, and the doctor switched me to Mounjaro since I have so much extra weight on me. He started me on the 5 mg pen since I had already been on Trulicity. I lost minimal weight on Trulicity. Some, but not enough to say it's awesome. The only side effect I've had on Mounjaro is occasional constipation/reflux, which is manageable. Maybe it is because I got past/thru all the nasty side effects while on Trulicity, and that minimized the effects of Mounjaro? I feel bad for all those that have had adverse effects on Mounjaro. I have lost about 10 pounds so far in just over 2 weeks, and I can tell a HUGE difference in my appetite. I mean HUGE. I'm not hungry like I used to be. In fact, this drug curbs my appetite SO much, that I have to force myself to eat sometimes, and in having to do that, it makes me instinctively want to eat more healthy food. This drug has helped with weight loss, and I am excited to see how much I will lose and get my A1C down."
- Lyn...
- Taken for 1 to 6 months
- October 15, 2022
"Been on Mounjaro for 5 weeks for weight loss. Started with 2.5 the first month, now on 5 mg. Lost 20 lbs so far. Been on 5 mg for 5 days now and extremely fatigued and weak, however, I’m not going to complain because I’m not hungry at all. Have no desire for food since being on 5 mg. You have to make yourself eat and drink because you feel full constantly. Mouth is very dry, so drinking water regularly is a must. Highly recommend for weight loss. Hopefully, the fatigue will go away once I’m into the second week of the 5 mg and my body adjusts."
Are you taking this medicine?
Your review helps others make informed decisions.- PP6...
- Taken for less than 1 month
- November 22, 2022
"Horrible experience taking this drug. I do not recommend taking this medication unless you want to die. I started taking 2.5 mg 6 days ago. Day 2 and 3 had no appetite and ate very little because the thought of food made me sick. Day 4 and 5 developed nausea, severe abdominal pain, and indigestion unrelieved by antacids. I also have lost five lbs because I am unable to eat or drink anything. I do not have any energy or feel like doing anything. Day 6 and I still feel sick. My fasting blood sugar this morning was 224 even though I am not eating or drinking hardly anything at all. It is noon, and I haven’t eaten anything because I’m afraid I will throw up. My heart rate is 120 and normally runs in the eighties. My doctor is out of the office this week for holidays. Just hoping and praying I don’t wind up in the emergency room. I will never inject this toxic stuff into my body again. I also read that it can cause thyroid cancer."
- The...
- Taken for 1 to 2 years
- December 24, 2024
"I tried Wegovy and Ozempic with no results. My endocrinologist switched me to Mounjaro, and I have had fantastic success. In 18 months, I have lost 100 pounds. My A1c is normal. I’ve been off insulin for 5 months, and I feel healthier and more energetic. The only side effects I have experienced are usually the day after I’ve taken my shot, I have an upset stomach, and I am not hungry at all. Best of all, I can shop in normal sizes now instead of plus."
More FAQ
- Mounjaro side effects you need to be aware of
- How much is Zepbound with or without insurance?
- How does Mounjaro Work for Weight Loss?
- Can you get tirzepatide from a compounding pharmacy?
- Tam...
- Taken for 1 to 6 months
- February 23, 2023
"I am overweight and was sent to an endocrinologist by my PCP. A1C came back 6.9, and I received the dreaded diabetes diagnosis. The endocrinologist asked me about my eating habits and suggested Mounjaro once a week injection. Sceptical I was, but I was willing to try to get my weight down and get my A1C down. First injection, no severe vomiting or anything. The only side effect I had was the constipation, I was put on a stool softener and take fiber daily, which eliminated that side effect. Within two months, I was down 15 pounds, have not given in to eating a Boston crème doughnut, on which I tend to binge, limited on my intake of food because overindulging makes me feel lousy and gives me indigestion. Within three months, my A1C is down to 5.3, and my weight is still going down. Thank you so much to the researchers who created this drug because it has saved my life and gotten me on the road to better health. The needle doesn't even hurt when I self-inject. I am grateful."
- Jca...
- Taken for less than 1 month
- October 7, 2022
"I just took my fourth injection, and I couldn’t be more excited! I’ve lost 10 pounds in three weeks, my appetite is controlled, I feel like I’ve finally got some hope to get my health where it needs to be. My morning fasting glucose is close to 100 (always near 140), no more crazy spikes hitting 200-300. I do get very tired the day of each shot. The first three days or so of my first injection, I was so ill (sick stomach). I got some Zofran, and that helped tremendously, so I’ll expect to need that with each dose increase. Looking very forward to 5 mg next week :) Ins won’t pay for it yet, even though I’m type 2, but I’ve got a coupon for it and paid $25 a month. Thank God, or I couldn’t get it, hopefully soon it will be covered."
- Anonymous
- Taken for 1 to 6 months
- June 26, 2023
"I had a very bad experience with Mounjaro. After two weeks of taking the 5.0 mg, I developed chest pains and a severe case of what I thought was reflux or heartburn. I really felt like I might be having a heart attack. I stopped taking it and reported it to my doctor. My doctor suggested I should continue taking it, but she would reduce the dose. I went back on metformin for about a month; then, I started the 2.5 mg dose of Mounjaro. I took the reduced dose for about two weeks and started having severe pains in my upper stomach. I went to urgent care, and they examined me and took X-rays, then sent me to the ER for further tests. After a CT scan, I was told my gallbladder was inflamed and needed to be taken out. I was in surgery by 10:30 am the next morning to have my gallbladder removed. I am 60 years old and have never had any problems this severe. I have fully recovered from the surgery but now have a $1,700 hospital bill. Thank God for insurance. The total bill was over $50,000."
- jrs...
- Taken for 1 to 6 months
- December 15, 2022
"I started on 2.5 mg for a month, then went to 5 mg. All I can say is that I'm tired of being sick. It feels like a stomach bug every time you eat something, and I'm talking about healthy food. I have had nothing but sickness. I have not lost any weight, I'm bloated all the time and just plain sick. It really has not done anything for me, but I hope this helps."
- Dut...
- Taken for 1 to 6 months
- March 8, 2025
"My appetite and being a lifelong ‘foodie’ hit a final conflict point four years ago when I lost my ability to work off my weight easily. My knee pain and depression combined to make me asocial, deeply uncaring about my condition and convinced of no hope. I am pretty miserable. At 15 mg a week, food has moved from center stage to a stronger support character. Only one bout of intestinal irritation has marred my experience with diarrhea, vomiting, pain. But my insulin levels remain superb and my glucose monitor has become a friend, not an inevitable betrayer."
- Tra...
- Taken for 1 to 2 years
- March 8, 2025
"LOVE IT! My GMI is constantly at 5.4. I've lost 98 lbs. and feel so much better. I started at the lowest dosage and am now just starting the 15 mg dose. Have had absolutely no side effects. Shot is so easy, painless, quick, and easy."
- Ski...
- Taken for 1 to 6 months
- March 5, 2023
"In November 2022, my ACI was 7.4%, and I weighed 258 pounds at 67 years old. The wake-up call was when I renewed my life insurance, a big jump in premium due to the AC1 and weight. I was now tagged as a Type 2 Diabetic. I was referred to an endocrinologist who did extensive blood work. It was agreed to go on Mounjaro 2.5 mg. The first week I suffered some side effects such as nausea, constipation, and acid burps. Within 10 days, the symptoms subsided due to stool softeners, lots of fruit (berries), and Nexium. The first month I dropped 10 pounds with no dieting, just was not hungry at all. I had no cravings, especially for sweets like cookies, donuts, and candy-all things that I used to eat. Fast forward to March 2023, I am down to 217 pounds and 20 more to go. I am now on Mounjaro 10 mg, it's a bit strong, but the results are fantastic. My AC1 is now 5.6%, which is fantastic. The bad news is nothing fits- all new suits for the spring."
- she...
- Taken for 1 to 6 months
- January 12, 2025
"I actually called my Dr. and thanked her for saving my life! I've dropped 33 lbs in 3 months. I no longer have swollen feet, my A1C has dropped a full point. Also, I no longer need Januvia or glipizide. It's amazing what processed sugar does to your body. I don't have the sugar craving anymore. My blood sugar is perfect every morning."
- Lin...
- Taken for 1 to 6 months
- November 10, 2024
"I’ve been taking 2.5 ml for 4 weeks and had few side effects apart from zero appetite, a little nausea, and a migraine (think the migraine was due to not eating). Now, week 5, increased to 5 ml and a different story: quite a lot of nausea, diarrhea, headache, and tiredness. Also again, total lack of appetite. Fortunately, these side effects more or less calmed down 2 or 3 days after taking the dose. I’m hoping it’s a temporary thing when you take a new dose - I can live with that."
- Din...
- Taken for less than 1 month
- December 10, 2024
"In the two doses, my blood sugar has been lower, my appetite has diminished, and I had no side effects. At the end of the second week (Saturday), I woke up during the night with stomach pain, diarrhea, and belching. After 6 hours, I finally vomited up undigested food that had been in my stomach for over 12 hours. It looked like I had just eaten. I avoided all food until Sunday morning, eating 1/2 of a plain English muffin. I had Lipton chicken soup, a piece of Bavarian pretzel, and a few french fries (picking from my wife’s meal). Monday, I finally felt hungry and had a Whopper Jr. (not a good choice I know), and Tuesday I woke up with food sitting in my stomach and one diarrhea BM. NOTE: I have not taken dose #3, nor do I plan to. This is slowing my digestion down too much. I have never had digestive issues, and I’m not going to start now."
- Jim...
- Taken for 1 to 2 years
- March 5, 2025
"I am a 67-year-old Type 2 diabetic who has been on Mounjaro for about one year, and I am pleased to report that I have dropped from 350 pounds to about 310 lbs without any other diet or lifestyle changes. My A1C dropped from 9.5 to 5.8. Mounjaro is the only medication I take for my Type 2 diabetes. I am up to 7.5 mg/0.5 liters after starting on 2.5 and then moving to 5.0. The only real side effect has been stomach cramps for an hour or so per week. It has really helped me in so many ways. A fan, thank you, Eli Lilly."
- Sus...
- Taken for less than 1 month
- March 5, 2023
"I have been on Ozempic 2 mg since it came out. When I couldn't get it due to shortage, I was prescribed Mounjaro 5 mg. Five days after eating my one meal a day, I intermittent fast, and I started vomiting. I spent the whole night throwing up every half hour. I figured it was a side effect and hoped I would improve. I had stomach and back pain, weakness, and was unable to eat. I was in bed until I had to get up and sit due to pain, sleeping off and on. I could only drink water. I got worse and finally, five days later, had my husband drive me to the ER. I know I should have gone sooner. I didn't take a second shot. I had a CAT scan and was told I had a bowel obstruction, and I would be admitted and there for a few days. If they couldn't resolve it through a tube down my nose, I would have surgery. Luckily, it was resolved by the nasal tube, but it was awful. My medical care pharmacist told me to try Mounjaro 2.5 mg. I was worried but did it. I didn't get nausea, but I had all these other side effects. I quit taking it."
- Ton...
- Taken for 6 months to 1 year
- February 26, 2023
"I started on a 2.5 mg dose for 30 days and had nothing positive or negative. The doctor increased it to 12.5 mg, and my appetite went to zero, stomach pain, throw-up, diarrhea, general nausea, and ill feeling, but did lose 15 lbs in 3 weeks, and my blood labs were near perfect. I was ready to quit until I saw this. The second month, my appetite came back slightly, and I learned to eat less and cleaner so it wouldn’t make me throw up, lost another 15 lbs, and it excited me to get back in the gym daily. Since the drug slows your digestion, it slows the bowel too, which gave me insane constipation and made sure I eat enough fiber daily. At first, the side effects are hell, but stick with it as they only lasted a month, then your body adjusts and you learn how to eat and work with it. The end results are worth it. It's been 9 months, and I have lost 35 lbs, labs are excellent, and for the first time, I have seen glucose under 100 in 30 years."
- 65Y...
- Taken for less than 1 month
- January 3, 2025
"I have just started the smallest dosage of Mounjaro 2.5mg/5ml and just took my 3rd injection (so I am 17 days in). I have noticed a marked decrease in appetite and have dropped 6.5 lbs (which is pretty good since I started on December 17th, right before the holiday meals and treats). The only negatives have been minor stomach distress (but I had that issue prior to starting Mounjaro), and on day 16, I have had indigestion and hiccups, which I am still trying to calm down. The hiccups stopped, but the indigestion is lingering. The injections are easy and not painful. My daily finger prick to monitor my blood sugar is more noticeable, so don’t let the injections scare you away. So far, it seems to be working very well."
- Roa...
- Taken for 6 months to 1 year
- March 27, 2025
"I loved this medication. Easy to use once a week. My A1C went to normal, weight went down to no longer be obese, and I could afford the $179/month. It did not upset my stomach. No side effects. I wish I could still use it, but the cost is way too high. Even with insurance, it is $750/month. So many online sites claim to sell it at a reduced cost, but I can't trust them."
- Jus...
- Taken for 1 to 6 months
- January 15, 2023
"I’ve been taking Mounjaro now for 4 months. I was prescribed it to treat my type 2 diabetes as well as for weight loss. Let me just say this drug has been a miracle! I started out at 268 lbs (5 ft 6 in male), I am now at 225 lbs! Over 40 pounds in 4 months! The only other weight loss program that helped me like this was the military! Now let me just say it’s not all Mounjaro, I’ve changed my eating habits and changed what foods I’m actually eating, and boom, working like a dream. My A1C has also dropped from 7.5% to 5.8%, this drug is an amazing stepping stone to a healthier life. The only side effects I’ve experienced since starting are loss of appetite and constipation, not too bad in my opinion!"
- Dea...
- Taken for 6 months to 1 year
- February 26, 2025
"I started on Mounjaro last May 2024, weighing 303 lbs. By December 2024, I lost down to 190 lbs. with my A1C at 6, and my glucose is 100, down from 286 in May 2024! Mounjaro is wonderful for me! I had nausea at first, but dosage of 15, no nausea whatsoever. I’ve had to buy all new clothes, and I love it!"
- Jan...
- March 19, 2024
"I started using Mounjaro at 2.4 mg, worked great, no side effects. After the doctor increased it to 5 mg, I developed severe stomach pain, both upper and lower. I couldn't tolerate the pain. I was taking oxycodone. Tried to live with the pain, but I couldn't take it anymore, so I stopped. Taking this medication, be very careful with what you're doing. My blood pressure was very high. My doctor was out of reach, so I went to another doctor. He prescribed a test on my pancreas, and the test came out bad. I was informed to stop this medication and take another test in six months. They didn't tell me what's wrong, they just told me to stop this medication and that I have to take another test in 6 months. It's very serious."
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Your review helps others make informed decisions.Learn more about Type 2 Diabetes
- Diabetes Medications and Alcohol Interactions
- FDA-Approved Weight Loss Drugs: Can They Help You?
- OneTouch Blood Glucose Meters
- Side Effects of Weight Loss Drugs
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- Which Drugs Cause Weight Gain?
Care guides
- Diabetes and your Skin
- Diabetic Gastroparesis
- Diabetic Hyperglycemia
- Diabetic Kidney Disease
- Diabetic Neuropathy
- How to Draw Up Insulin
- Hypoglycemia in a Person with Diabetes
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"In January 2023, my A1C was 12.2, and my weight was 290-295 lbs. I had tried everything since 2009 to control my diabetes, even Ozempic and Trulicity. I was taking 4 Metformin tablets a day, along with many other drugs. Now, in January 2025, my A1C is 4.6, and my weight is 183 lbs. The only thing I take daily is a multivitamin. I no longer have to follow a strict type 2 diabetes diet. However, my taste has changed over this time, and I eat fairly healthy. I am currently on 15 mg, but the doctor is talking about reducing the dosage to just maintain. It’s been a godsend. I have not felt this good since I was a teenager."