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Gelsyn-3 and Headaches: What Users Say

Headaches: mentioned by 5 users (12.5%)

Based on user experiences from 40 Gelsyn-3 reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

pain 25.0%
swelling 20.0%
back pain 12.5%
headaches 12.5%

Reviews for Gelsyn-3

Commonly mentioned side effects
  • jen...
  • Taken for less than 1 month
  • December 30, 2020

For Osteoarthritis "I have bad knees, walk my dog, garden, and swim. I had the first round of Gelsyn-3 and felt fine. The second injection hurt bad in my right knee. Took my dog for a little walk and two hours later my right knee hurt so bad I was dragging my leg. Four days later, I cannot bend my knee to get in the car. I will not get the third injection. Someone else was complaining about a headache, I also had one."

1 / 10
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46 Report
  • bre...
  • Taken for 1 to 6 months
  • June 1, 2023

For Osteoarthritis "I received the Gelsyn-3 knee injections, one each week for 3 weeks. The first injection, my knees were sore, but I really didn't feel much different as my knees still hurt as before. I received the second injection, and that next day I began having more pain than I had ever had. I started hurting behind my left knee, which had never hurt me before. I felt fatigued and had leg and thigh pain at night that I couldn't sleep most nights. I really didn't want to get the third shot but was advised by my doctor that after the third shot, I should start feeling some relief. I told him my knees hurt worse than they did before, but he said that should go away, so I got the third injection. A few days after the third injection, my legs started hurting all over, especially at night. I had a headache, my lower back hurt, and I was just sick all over. This went on for several weeks. It's been 6 weeks after the injections, and my knees are no better. I would never do this again, NEVER!"

1 / 10
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21 Report
  • Can...
  • August 4, 2019

For Osteoarthritis "I had my first Gelsyn-3 shot 8-2-2019. I use a cane to walk. I know I had a bad headache, nausea, and my body hurt, I didn't feel like eating. My knee has no relief at all yet. Knee replacement is the last option. I pray that by the 2nd injection it will improve."

3 / 10
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32 Report
  • gin...
  • Taken for less than 1 month
  • June 5, 2022

For Osteoarthritis "I am two weeks out following my third shot of Gelsyn-3, and I have had a slight pain improvement, but the bone-on-bone pain still keeps me from walking any sort of distance, like through a grocery store. I had a headache and back pain at first, but that seems to be subsiding. I am hoping in two more weeks, I will have greater mobility with less pain, but most of these reviews seem to be of a negative result, so I am discouraged. I was hoping these injections would save me from a replacement, but so far, I have not had full pain or mobility relief."

5 / 10
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9 Report
  • dfs...
  • Taken for less than 1 month
  • September 6, 2018

For Osteoarthritis "Earlier today, I had the 3rd dose of Gelsyn-3 in both knees. As in the 1st and 2nd injections, I developed a slight fever and headache, but this has really improved the pain in my knees."

8 / 10
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37 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.