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Sitagliptin for Diabetes, Type 2 User Reviews (Page 2)

Brand names: Januvia, Zituvio

Sitagliptin has an average rating of 4.6 out of 10 from a total of 138 reviews for the treatment of Diabetes, Type 2. 29% of reviewers reported a positive experience, while 51% reported a negative experience.

Reviews for Sitagliptin

  • Mitch...
  • Taken for 1 to 6 months
  • December 15, 2015

Januvia (sitagliptin) "I have had no side effects from Januvia. My A1C went from 9.2 to 5.5 using 1500 mg of Metformin and 100 mg Januvia, and adjusting my diet and exercising a bit. I am lucky in that neither Metformin nor Januvia seems to bother me. There is a savings certificate on the Januvia site to keep the copay down to $5, normally it would be $55 for me."

8 / 10
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  • Fay
  • Taken for less than 1 month
  • October 16, 2019

Januvia (sitagliptin) "I've been taking metformin, and it worked, lost weight, but gave me severe diarrhea. So I was prescribed JANUVIA. The second day, I had a crick in my neck on my left side. Woke up again, it spread to my right side. Found out it swollen up my lymph nodes. Painful. My body ended up so sore, and I was really tired. Please don't take this medication. I'd rather deal with metformin after this."

1 / 10
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  • Ozzym...
  • Taken for 1 to 2 years
  • January 6, 2013

Januvia (sitagliptin) "If I would be more compliant with my diet and exercise regimen, Januvia would help me stay under 6. No noticeable side effects, although after reading other reviews, possibly the lack of sleep might be attributed to it. I had some joint pain but I take CoQ10 and that made it go away. Not sure if that was from Januvia or the statins. Overall, I like it. Can't wait until, with better compliance, I can come off these costly medicines."

9 / 10
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Frequently asked questions

  • Anonymous
  • June 7, 2009

Januvia (sitagliptin) "Metformin and Glipizide weren't working well enough to keep my blood sugar in control. My doctor added Starlix at meals and that seemed to help some but still didn't produce the desired results. As a last resort to beginning insulin, he prescribed Januvia. Wow! What a difference. My morning readings dropped from the 170s into the 80-90 range within a week or two. Only negative side effect is occasional constipation, but nothing I can't deal with. Have been taking Januvia for about four months and one positive benefit I've noticed is a decrease in cravings or appetite in the evenings (the worst time of the day for me)."

9 / 10
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  • ddw_A...
  • May 13, 2015

Januvia (sitagliptin) "The doctor put me on Metformin, which my liver didn't fare well with, and then tried the Januvia 100 mg. After 2.5 weeks, I told him I was experiencing facial, hand, and eyelid swelling and that I felt this wasn't a good fit for me. So, he prescribed Januvia 50 mg, which after three days, caused nausea, upper abdominal pain, orange urine, and skyrocketing blood glucose from low 120's to well over 200's after eating. I immediately quit taking it."

2 / 10
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Are you taking this medicine?

  • Bird
  • May 2, 2019

Januvia (sitagliptin) "After seeing my doctor, he took me off the Metformin ER 500 mg because it wasn't helping me. Therefore, he gave me a sample box of Januvia 100 mg to try out. I had the worst experience ever. After 2 days of taking this medicine, I began having severe pains in my stomach, back, and legs to the point I couldn't walk. The pain was intense, excruciating, agonizing. I discontinued the medicine after the second day. I have another doctor appointment, and I will be sure to address this issue. If you can maintain your diabetes with diet and exercise, please do."

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  • Reidski
  • July 1, 2015

Januvia (sitagliptin) "I guess medicines don't work the same for everybody. I have been taking Januvia (50 mg) for 6 months now and have had no side effects at all. I take 3 metformin daily. My blood sugar readings have gone down from 8.1 to 6.9 (Canadian scale). I thought I was heading for type 1, but Januvia really works for me. Like many things, you could just try it and see for yourself."

10 / 10
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  • Leopa...
  • Taken for 2 to 5 years
  • November 6, 2013

Januvia (sitagliptin) "No noticeable difference with Januvia, which was added to Metformin, Glipizide, and now Victoza. I have been taking the first three meds for a few years. My question is that I often see the entire Januvia pill, undigested, in my stool. Why is this? I tend to be constipated but do not take laxatives. I told my doctor, but she did not seem concerned. If this med is just passing through my body, what is the point? I take my Januvia and Glipizide before dinner, and my Metformin before breakfast and my nighttime snack. (I have high morning sugars.)"

5 / 10
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  • SMC
  • Taken for less than 1 month
  • September 23, 2018

Januvia (sitagliptin) "2+ wks ago, my left ear felt like it had water in it, like after swimming, and I have a swooshing sound in my ear 'til it comes out. After the 2nd day, I knew it wasn't water. Just annoying, not painful, so I knew it wasn't an ear infection. After a week, I began to get bothered since it hadn't gone away and decided to go to urgent care. The doctor said nothing was there; no wax buildup, fluid, or infection. Told me to tug on my ear, and if it was still there after 2 weeks, to call my GP for an ENT referral. A week later, I noticed hearing loss, so I decided to call my GP and get a referral. Today, I've been thinking about what I have done differently that could have caused this. I have never had ear issues. In 44 years, I have had 2 ear infections, and I swam almost daily in college. After thinking about it on and off today, something finally went off in my brain that reminded me of my newest Rx, Januvia. I stopped taking it today. Now I'm praying damage is reversible. Very disappointed my Google search answered my suspicions, and 2 doctors couldn't. Side effect = ear congestion."

1 / 10
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  • XYD
  • July 28, 2016

Januvia (sitagliptin) "The side effects of 50 mg Januvia with Metformin ER were horrendous. Painful finger joints. Swelling fingers. Stuffy ears. Unbelievable dizziness, which caused nausea and dry heaves. The diarrhea has been so awful that I can't leave home. I stopped the Januvia 4 days ago. The dizziness stopped first. Then my hands settled down. The diarrhea has not stopped. My doctor believes that I have parasites because Januvia, in conjunction with Metformin ER, doesn't cause diarrhea like this. Getting tested tomorrow, and I have to go back on Januvia. Not looking forward to this at all. What a mess."

1 / 10
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54 Report
  • wrang...
  • November 6, 2016

Januvia (sitagliptin) "Januvia caused me severe muscle cramps, bad enough that I should have gone to the hospital because of the pain. I also got where I could not sleep at night while on Januvia. It was also not effective for me. I was placed on Invokana in addition. I am still having side effects after stopping both of these. My doctor did not even bother to return my call when I took myself off of Januvia. Because the spasms are in my neck-shoulder area, it has caused me to drop 40 pounds off of my weight lifting workout. This is not good. I would encourage anyone considering Januvia or Invokana to do research on the side effects because my side effects were not common, but the drug company lied to doctors about all of the side effects."

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  • Shorty
  • Taken for less than 1 month
  • September 21, 2019

Januvia (sitagliptin) "I took Januvia for approximately 6 weeks. As time went on, I started to feel stiffness in my right shoulder, I thought nothing of it. Then my neck started stiffening up to the point I could barely drive, and at night, if I laid on my back, I started to wake up through the night. It felt like my breathing was cut off, and still, I never thought it might be Januvia. I was taking 50 mg in the morning with my metformin, then it was like my joints in my foot stiffened to the point I could not walk. I called my doctor, she told me to stop taking it right away. I'm well now, but it took me 7 weeks to recover from the stiffness."

1 / 10
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  • esamp
  • Taken for 1 to 6 months
  • December 13, 2018

Januvia (sitagliptin) "My type 2 diabetes spiked after getting a high dose of steroids. Januvia was the answer. I took it with zero side effects for several months. Then I noticed an extreme weight loss, currently 82 pounds lost and unfortunately counting. I stopped taking it, and I still had zero appetite. Six months later, and I'm drinking Boost to try and not lose weight and get my appetite back. Any food I liked is no longer good to my taste buds. I can't stomach the taste of most food. After eating, I become nauseous. But my blood sugar is running great."

8 / 10
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  • Insom...
  • Taken for 6 months to 1 year
  • November 17, 2019

Januvia (sitagliptin) "I was diagnosed with diabetes a few years ago and was given Metformin. Immediately, I had severe stomach pains, nausea, and vomiting. I was switched to Amaryl (dropped my blood sugar constantly), then to Oseni (which worked miracles with the right diet). Then there was a shortage, so I was prescribed Januvia! Januvia doesn't drop my blood sugar if I haven't eaten in a while, and I don't have to be as strict with my dieting (no pasta with Amaryl and Oseni vs. pasta with Januvia). With Januvia, my A1C was at a 6.5, and I didn't have any nasty side effects. Januvia is the only medicine I'm on right now for my diabetes, and I'm actually glad my doctor fought to get me the medicine."

10 / 10
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  • Steve...
  • Taken for 6 months to 1 year
  • August 31, 2019

Januvia (sitagliptin) "Had A1C of 6.2 seven years ago and was put on metformin. Had side effects, so in January 2019, I was put on 50 mg Januvia. My A1C went up to 7.2. Four months ago, I was switched to 100 mg, and now my A1C went to 7.5. I am very active and walk 4 miles every day. I do not eat carbs in excess of 40g a day, no sugar, and have maintained weight. It does not work on me at all. I will stop it now."

1 / 10
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  • coramac
  • October 29, 2011

Januvia (sitagliptin) "I have been on Januvia for about 7 weeks and have had diarrhea the whole time. I'm also on metformin, and between the two, I don't think I've had a solid poop in weeks. However, my blood sugars are down from 25 to under 10 most days. I have gained 15 lbs, and I can't handle the cold this year, always getting chilled. I also have to take mine with food, otherwise, I get an acid stomach all day, no matter what I do. I will be talking to my doctor to see if there are other options or if the benefits outweigh the negatives."

5 / 10
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  • Bamafan
  • June 8, 2008

Januvia (sitagliptin) "I have been on Januvia for 6 months. My sugar levels are great. No side effects. It makes me feel not hungry. I was taking Amaryl once a day and metformin twice a day, plus Diovan for blood pressure. Now I am only on Januvia. I started going to the gym and eating healthier, I now have lost 60 lbs. Personally it is the best medicine I have found."

10 / 10
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  • Andrew
  • July 24, 2015

Januvia (sitagliptin) "Been taking Januvia 100 mg a day for 12 days, and it has just started to work really well. Blood sugar is 6.9 mmol at midday. Very pleased, and I have no side effects. Fortunately, in England, diabetics get their meds free on NHS."

10 / 10
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54 Report
  • Princ...
  • November 26, 2015

Januvia (sitagliptin) "I would have given it a 10 because I felt it was really working for me. But... after about 6 days of having a horrible stomach ache, I've thrown in the towel. I just can't take it. I'm really bummed out because I can't take Metformin either. :("

6 / 10
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  • Iwd
  • Taken for less than 1 month
  • September 25, 2015

Januvia (sitagliptin) "My insurance refused to pay for my Oseni, they told my doctor to try Januvia. During the first 7 days, I developed a constant cough, along with upper stomach pain and diarrhea. I stopped the medication, and symptoms ceased. I started back on the meds yesterday, and severe stomach pain returned, along with diarrhea. Stopping this medication for good-it's not good for me, the side effects are too painful."

1 / 10
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  • Lulu
  • July 17, 2019

Januvia (sitagliptin) "Endo prescribed Januvia along with Farxiga and Metformin 4 months ago. Regular ER Metformin caused horrid gastric distress (diarrhea). Two doses of Januvia and the upper abdominal ache started, constipation, scalp itching, fatigue, and extremely high blood sugars. Now prescribed TEVA manufacturer Metformin instead of the generic brand that costs nothing at certain pharmacies. TEVA doesn't use the same fillers as the other Metformin - I take two with dinner and working to go to four a day with no GI issues. Before Januvia, my sugar was controlled - never going over 180. With Januvia and Farxiga, my readings are in the high 100s, 200+ - I called my endo and told her I had stopped the Januvia (stomach ache is gone). She said to also stop Farxiga since it appears that both drugs are not helping my sugars. I am going back to my routine I had BEFORE Farxiga and Januvia. Those two drugs' cost is $1600 each for three months WITH excellent insurance."

1 / 10
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  • TimO
  • Taken for 2 to 5 years
  • September 20, 2018

Januvia (sitagliptin) "My A1c was 18.1, and I was prescribed Januvia 100 mg tablets after a bad reaction to Metformin (went from being regular to not going for weeks at a time). Januvia, taken with 10 mg of Glipizide once a day, has taken my A1c down to between 5.5 and 6.0. I've had none of the side effects mentioned in other reviews here, although there have been times when my glucose levels have taken me into the hypo range, 50 mM. Don't care for that too much. Beyond that, I have nothing bad to say about this drug in the two years I've been taking it. It seems to keep my A1c where it should be, and my doctor is happy with the results."

10 / 10
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  • Love...
  • Taken for 1 to 6 months
  • September 29, 2015

Januvia (sitagliptin) "I have been diabetic since 1989 and have gotten worse over the years. My A1C has been climbing steadily. I take Metformin 2,500 mg per day. In March, my doctor started me on Januvia also, and I can't believe the difference. My A1C went from 9.4 to 7.0 in 4 months. I am also surprised I haven't had any side effects because it seems many meds bother me. My problem now is my new health insurance won't cover Januvia as of January 2016. Yuck."

10 / 10
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  • Joe...
  • October 9, 2015

Januvia (sitagliptin) "Works really well, my doctor is happy now. The only side effect is large, hard stool, which plugs the bathroom plumbing up every time, so I need to carry a plunger with me when away from home. Have been on it for about 3 months now, 100 mg daily, along with 1000 mg Metformin twice daily and 4 mg Glipizide twice daily."

10 / 10
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  • Anonymous
  • November 16, 2011

Januvia (sitagliptin) "I've been on Januvia for about 5 months after being on Metformin alone twice a day for 6 months. My average blood glucose before meals is in the 80s, even though I am non-compliant with my exercise schedule, I have to admit it. But I noticed mild knee pain, I'm not sure if it is related to the medicines. Other than that, I'm happy with Januvia."

9 / 10
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66 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.