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Sitagliptin for Diabetes, Type 2 User Reviews (Page 3)

Brand names: Januvia, Zituvio

Sitagliptin has an average rating of 4.6 out of 10 from a total of 138 reviews for the treatment of Diabetes, Type 2. 29% of reviewers reported a positive experience, while 51% reported a negative experience.

Reviews for Sitagliptin

  • Jay
  • Taken for 1 to 6 months
  • September 27, 2018

Januvia (sitagliptin) "I took Januvia as a replacement for Metformin for a short period of time and found it caused me to start experiencing shortness of breath. I quit after another doctor told me Januvia was the cause of the problem. Since quitting Januvia, I continue to have shortness of breath, and with even very little activity, I experience chest pain. My cardiologist assures me I have no heart problems and no blockage but does not know what is causing my chest pain. I am beginning to think that my chest pain is being caused by permanent damage from the Januvia to my breathing, resulting in my chest pain. I am now on insulin."

2 / 10
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37 Report
  • EARL...
  • Taken for 1 to 6 months
  • July 5, 2023

Januvia (sitagliptin) "Just started taking Januvia 100mg. Thirty days and it's dropped my blood sugar level from 200+ to an average of approximately 150 without any known side effects. Praise God and Januvia Pharmaceuticals."

10 / 10
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11 Report
  • texas...
  • July 13, 2009

Januvia (sitagliptin) "I couldn't tolerate metformin at all. Moving to Januvia was wonderful. I've been on it for a year and a half and have had no side effects whatsoever. Blood glucose numbers and A1c (5.7!) have been good, but I also exercise and closely watch my diet."

10 / 10
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73 Report

Frequently asked questions

  • yukid...
  • Taken for 1 to 2 years
  • August 29, 2016

Januvia (sitagliptin) "Januvia side effects include crippling, debilitating pain and swelling. Dad's been taking it since March 2015, and by August could barely walk. He had joint swelling and excruciating pain. Doctor after doctor visit. No clue! Called me, his daughter, RN BSN, and we returned to the doctor wanting to know why he didn't know more about this drug's side effects. NONE OF THEM DO! A friend veteran, same thing. Could hardly stand the pain, talking about swollen and angioedema. They even ran heart tests! It was the Januvia, and my dad and the vet, taken off Januvia, have completely recovered. The veteran had even been referred to a rheumatologist. My dad is now taking chromium type supplements and watching his carbs. Doing very well."

2 / 10
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45 Report
  • Melissa...
  • November 29, 2016

Januvia (sitagliptin) "Worst drug I've ever been on. My sugars went from a controlled 120 to over 350 in a matter of weeks. Invokana was giving me severe yeast infections, so I asked for a change. Now I don't have YI, but this medication doesn't do anything to lower my sugar. If anything, it makes my sugar higher. Seeing my doctor Thursday to switch back or to something else."

1 / 10
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44 Report

Are you taking this medicine?

  • ChapKat
  • Taken for less than 1 month
  • April 16, 2016

Januvia (sitagliptin) "This drug came after a bad reaction to Metformin. It is definitely not any better. From day one, I have had diarrhea. And the heaviness in my arms is still present. Now, the leg spasms are showing up, but it is the abdominal pain and the excruciating back pain that take this drug out of the running. I am coming off of it. I can't afford for this drug to kill me. Nausea has been a problem within 3 days of beginning it. Be wary...be alert."

1 / 10
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46 Report
  • Neil...
  • Taken for 1 to 6 months
  • September 14, 2019

Januvia (sitagliptin) "My A1C was under 7 with Metformin and Starlix. My Dr. added Januvia 100 mg. My A1C increased over 7. The worst part was, my eyes started itching badly and got swollen. Once I stopped Januvia, my eyes got normal again."

1 / 10
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  • Karme...
  • August 21, 2018

Januvia (sitagliptin) "Aug. 20, 2018 - After 10 days of taking Januvia 25 mg per day along with Metformin 500 mg twice a day, I started getting upper abdominal pain and back pain at the same time. The pain came and went all day long. At first, I didn't connect it to the Januvia, but after 5 days of the pain getting worse, I called my doctor's office. They told me to go straight to the ER at the hospital. I had blood work done, an EKG, and an ultrasound of the affected area. Everything came back negative. I was told to discontinue the Januvia and go on a very light diet of broth, juice, etc., which is what I did. It took 5 days before the pain subsided. I have done a lot of research online since then, and I see I'm not the only one that had this problem."

1 / 10
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35 Report
  • Ritac...
  • August 24, 2015

Januvia (sitagliptin) "Been taking Januvia for almost 2 wks. Almost instantly had difficulty breathing, rapid heartbeat, and coughing. I have more energy, but I don't like the side effects. I have a hard time talking because I'm constantly coughing, and that's not good, especially when you're a college instructor. Just called my MD to see if there's something else I can try."

3 / 10
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47 Report
  • Vic
  • Taken for 6 months to 1 year
  • December 9, 2018

Januvia (sitagliptin) "I had a 9.6 A1C. I have been on Januvia for approximately 1 year, taking 100 mg daily. My A1C dropped to 6.1 in 3 months. My doctor said to try taking half of a pill for the next 3 months. My A1C is now 5.1. No side effects. I also am a sepsis shock survivor from 2016. I left the hospital with 50% kidney function and continue having the same function numbers, having my kidneys checked regularly."

10 / 10
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33 Report
  • Bagsh...
  • September 20, 2017

Januvia (sitagliptin) "Took Januvia for two months and started to get joint pain, which got so severe I could hardly walk. I have been off it for one week but still have pain in my legs, especially the right. Would never recommend this drug to anyone, the side effects are really bad. The medication is expensive."

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  • DLano
  • August 30, 2016

Januvia (sitagliptin) "Took Januvia for several years. Had tightness/pain in my lower abdomen, which I assume was related to my pancreas. Blood sugars did not get lowered. Stopped taking Januvia, and my sugars went down 30 points. My cost went from $47 to $167 for a 30-day supply because of Medicare Donut Hole, so I had to stop. Drug is way too expensive for what it does."

5 / 10
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41 Report
  • postal
  • Taken for 2 to 5 years
  • April 24, 2016

Januvia (sitagliptin) "Not sure about any medicine I take. But Januvia was 56 bucks on Sept 14, now it is 96 bucks. Got a letter from them after complaining, their answer priced competitively. What does that mean when there is no competition????? There is no generic, and they know it. Tempted to take myself off of it, found that if I forget it for two days, I crash when resuming the medicine."

3 / 10
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42 Report
  • Hari
  • February 22, 2010

Januvia (sitagliptin) "I have been on Januvia for eight weeks. No side effects, no problems. The blood sugar two hours after eating is well below 120. However, the fasting blood sugar level does not drop below 100. Overall, I am very satisfied. It is very expensive but good."

10 / 10
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59 Report
  • Ubu
  • September 7, 2018

Januvia (sitagliptin) "Taken for 3 days. I have cough- respiratory problems- put on inhalers. Diarrhea, savage pain at night that I feel like I will not live until morning. Quit taking it and reading all the side effects with it I wonder why this is even prescribed. I hope the side effects go quickly. I can hardly walk and breathe at the same time. Only on 3 days."

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30 Report
  • CABHOLT
  • Taken for 1 to 6 months
  • July 3, 2019

Januvia (sitagliptin) "I took Januvia for a few months to lower my A1C, prescribed by my endocrinologist’s APN, and my PCP took me off because she didn’t see the benefits and didn’t understand why I was prescribed it in the first place. My PCP said Januvia is usually prescribed for older patients (80 years +) with kidney issues. I am 50 and have no kidney problems, but I experienced horrible stomach issues on Januvia and regretted taking it. Why is this being prescribed? It didn’t work for me and didn’t lower my A1C. Period."

1 / 10
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27 Report
  • CRjC
  • January 14, 2017

Januvia (sitagliptin) "I am unable to take this medication because Merck will not let me use the coupon because I am on medicaid. What difference does it make what insurance I have if they are not covering it and I have to pay cash anyway? I find this discriminatory. The coupon should be available for anyone paying for the medication."

1 / 10
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35 Report
  • Happy...
  • July 1, 2008

Januvia (sitagliptin) "Love this drug. I have been on Januvia for at least a year and a half now. When I started, I noticed that, in combination with metformin, if I am walking or exercising, within a few (1-3) hours after taking a pill, my sugars are terrific and going down significantly. I couldn't achieve this with gliburide and metformin alone. I used to have under-skin tissues all over the body formed like bulges under the skin, many bulges, actually. After I started Januvia, all those accumulations of tissue disappeared."

10 / 10
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61 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • October 23, 2019

Januvia (sitagliptin) "I took Januvia for about five to six months. This was back in early 2012. I developed the side effect of terrible tremors. I finally stopped taking it. Although the tremors and handshaking lessened, they have never gone away."

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24 Report
  • Lucy
  • Taken for less than 1 month
  • July 2, 2019

Januvia (sitagliptin) "Started Januvia a week and a half ago - metformin gave me major gastric distress. Januvia has been horrid - upper abdominal ache and constipation. My blood sugars have been very high since starting Januvia. Sugars have never been above 190 until Januvia. I am going back to metformin and deal with the diarrhea. I will let my doctor know what is going on again."

1 / 10
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25 Report
  • Harry
  • Taken for less than 1 month
  • April 22, 2018

Januvia (sitagliptin) "Terrible drug worked okay the first few weeks, then I began developing the most severe diarrhea and dysentery. I would spend 3 or 4 days glued to the toilet, going through 20 to 30 pairs of underwear (diapers). I was pooping in my sleep in bed. The dysentery went away when I discontinued the pills but came back immediately when I resumed taking them. Became dehydrated, shortness of breath, sweating, dizzy, vomiting, dry heaves, and felt weak. Severe stomach cramps ended up in the ER room with an IV drip of morphine to stop the pain. I almost died."

1 / 10
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29 Report
  • User...
  • Taken for 1 to 6 months
  • November 19, 2019

Januvia (sitagliptin) "Very frequent need to go to the toilet after two months of Januvia dose 100mg once a day, like need to go to the toilet every thirty minutes day or night. It's the first time I have seen this although had type 2 diabetes for more than thirty years.stopped using it and its getting better now."

1 / 10
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23 Report
  • JIM
  • Taken for 6 months to 1 year
  • January 27, 2020

Januvia (sitagliptin) "I've been taking Januvia for 6 months along with Metformin and Jardiance and my A1C went from 9.6 to 8.2 so the combination is working some. The only side effect I'm having is itching and it is bothersome. I will see if there is something new I can take other than Januvia because of this daily itching. Other than that no side effects .....So far...."

6 / 10
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22 Report
  • vin1z
  • November 16, 2011

Januvia (sitagliptin) "My body had developed resistance to sitagliptin after 45 days of use. It worked fine with my body for 40-45 days and became ineffective later. My doctor switched me to glipizide/glimepiride, which works with my body effectively even after 1 year of use along with metformin combination."

2 / 10
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47 Report
  • Anonymous
  • July 13, 2010

Januvia (sitagliptin) "I have been on Januvia 100 mg for about 1 year, 1 pill per day. My blood sugars ran from 124 to 138. The past 4 weeks my doctor increased it to 3 times a day because my blood sugar started to go up to 152-240. I wish I knew what happened. My diet is the same, and at first, I lost weight, and now am at a standstill. Maybe I should change. I have trouble sleeping and take something for that. Hope it will change soon."

5 / 10
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50 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.