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Sertraline for Obsessive Compulsive Disorder User Reviews (Page 3)

Brand names: Zoloft

Sertraline has an average rating of 7.9 out of 10 from a total of 285 reviews for the treatment of Obsessive Compulsive Disorder. 72% of reviewers reported a positive experience, while 11% reported a negative experience.

Reviews for Sertraline

  • Logan...
  • Taken for 6 months to 1 year
  • July 4, 2013

Zoloft (sertraline) "Zoloft has saved my life. I have been on Zoloft 200 mg for 7 months and the results have been amazing. I suffered from severe OCD, anxiety, and mind racing. Zoloft and Abilify 5 mg have completely eliminated my symptoms. I can now live and enjoy my life thanks to Zoloft 200 mg and Abilify 5 mg."

10 / 10
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111 Report
  • imnot...
  • Taken for less than 1 month
  • July 27, 2017

Zoloft (sertraline) "I have been on this medication for exactly 20 days now, and believe me when I say it has saved my life! I dealt with extremely disturbing intrusive thoughts, leading to severe anxiety and depression for 4 years. After almost giving up completely on my life, I finally told my GP about my situation. He, along with a psychologist, confirmed the OCD and put me on 50mg of Zoloft for the first week, then increased to 100mg. I finally feel like myself again! OCD is minimal and definitely manageable, to the point where it barely bothers me, and I know it'll improve because it's only been 20 days! It does cause a little diarrhea, but it's so worth it."

9 / 10
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  • rey11nj
  • Taken for 5 to 10 years
  • February 13, 2024

Zoloft (sertraline) "My OCD reared its ugly head at 22 years old at the end of 2018. My doctor put me on 50mg Zoloft, and within a few months, my life felt better than it had in years. In fact, Zoloft showed me I was suffering from general anxiety and some social anxiety long before my OCD. I just didn't notice because I thought it was just who I was. But with Zoloft, I became outgoing, motivated, discovered I'm in fact an extrovert, and excelled in my career. Unfortunately, after feeling better, I stopped them abruptly and my symptoms came back. I tried in the past few years to stay off meds and take a more holistic approach. However, due to increased responsibilities and life stressors, this was just not sustainable. So, I am back on them and 3 weeks in. The first 2 weeks were rough, but I'm starting to feel much better this week. I'm not saying I have to live on them, but the reality is every time I take them, life is much better. I will stay on them for as long as my doctor says. Therapy and psychiatric visits are important."

10 / 10
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12 Report

Frequently asked questions

  • Anony...
  • Taken for 1 to 6 months
  • October 22, 2022

Zoloft (sertraline) "Medication gives you hope when you are done and desperate and also can help you stay balanced and not let OCD bring you down to the ground again. Zoloft needs time to help you. And you have to wait. I am having pure O since my teenage years. After a period of stress and bad days, my OCD got worse. I had intrusive negative thoughts, lots of thinking all day even when I was trying to sleep. When depression comes and you have OCD, you know it's a big problem. Panic and stress. You feel like you are losing your mind. Zoloft helps chemically your brain to feel better. 50mg is a small dosage, but you have to try it for a start. Raising your dosage might help more. It helps you fight your thoughts, and since chemically your mind is in a better state, this makes it easier for you. You have to let yourself be helped chemically, otherwise, you are alone and struggling. You have to find the right medication and dosage for you. Don't let yourself suffer. We need help to fight it. Good luck."

8 / 10
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  • Sam
  • Taken for 1 to 2 years
  • March 29, 2021

Zoloft (sertraline) "I have strong and scary intrusive thoughts that have been driving me crazy. At about 17 years of age, I started off with fluvoxamine for about 2 years. I was okay, then it started to come back, so the doctor eventually increased my dose from 50 mg to 100 mg. I felt better for 6 months, then again increased from 100 mg to 150 mg and so forth, up until I reached 300 mg. I saw a new psychiatrist and he changed it to fluoxetine, went for months and didn’t help, then I was put on clomipramine for months. Also didn’t work. The psychiatrist put me on clomipramine, risperdal, and Zoloft that was just added now, so I can’t say much about Zoloft just yet, but I feel so hopeless. No medication is helping at all. What do I do? Someone help me through this nightmare. :(("

3 / 10
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Are you taking this medicine?

  • Jenev...
  • Taken for 1 to 6 months
  • August 13, 2013

Zoloft (sertraline) "I have struggled with obsessive-compulsive disorder since I was 6 years old, hiding it from family and friends because I had no idea what was going on when I was little. I then got so stressed I had shooting pain through my whole body and went on Cymbalta for 6 months. Then, I got off of it and was back to normal with no pain, just OCD. I then got sick with vomiting, couldn't eat, felt scared to be alone. My doctor told me it was anxiety. He gave me Zoloft 25 mg and started me on it really slow. I am on 50mg and a half once a day now, and I am back to normal, no vomiting or bad thoughts. I still have some bad moments of OCD, but they don't last long. I have recommended this to people! I am 26 years old and finally can enjoy my life."

9 / 10
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100 Report
  • lavid...
  • March 1, 2012

Zoloft (sertraline) "I suffer from OCD and intrusive/compulsive thoughts that create almost unbearable anxiety. In Oct '11, I was prescribed Zoloft and found it to work incredibly. On 100mg, my OCD is 85-90% gone, and I can easily rationalize and even blow off my intrusive/compulsive thoughts about 95% of the time. I felt better within a week, but it did take 3-4 weeks for me to notice its full effect. I'd describe the feeling it gives as light, airy, and happy/drifty. I haven't experienced any side effects, and haven't gained any weight. On a side note, I also found that one huge factor contributing to my anxiety is too much caffeine, even when taking Zoloft (I still have one cup of coffee to wake up in the morning, but I've found that's my strict limit)."

9 / 10
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109 Report

More FAQ

  • Spong...
  • June 10, 2017

Zoloft (sertraline) "I developed a very specific form of OCD in my early 50s that is commonly described as 'Ear Worms'. It is where a song or a snippet of a song gets stuck in your head and keeps playing over and over. It got so bad it was literally driving me insane. I would have a snippet playing nonstop for WEEKS! Day and night (kept me awake until I fell asleep from exhaustion). Played at work CONSTANTLY where I couldn't focus. I would be in meetings unable to pay attention because I would have a song blaring over and over in my head. After ramping up doses, I settled at 100mg/day of Zoloft which has SAVED MY LIFE! It works! I can listen to music again and not yell at my wife when she sings. And I have no side effects."

9 / 10
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71 Report
  • Mnash
  • Taken for 6 months to 1 year
  • June 15, 2023

Zoloft (sertraline) "Ended my years of mental suffering and torture that is OCD. Zoloft has been a God send for me. Taking a high dose of 125mg daily has helped me get my life and my brain back...thank you times a million for this medicine."

10 / 10
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  • Gordon
  • Taken for 1 to 6 months
  • February 20, 2024

Zoloft (sertraline) "I had taken Prozac and Lexapro separately as a middle-aged male and had horrible urine retention where I had to stop taking both. My last hope was Zoloft and I have been taking it for 1 month and the urine retention was not as bad and eventually I overcame it. The beautiful thing about Zoloft is it has less side effects as well for me than other SSRIs. It's been almost seamless as far as it working well with my system. After one month, it's caused my ruminations to decrease at least roughly by sixty percent. I never thought this was possible because my ruminations had gotten so bad I could no longer function. Anyone that is thinking of using this drug, just give it a chance. It is true you need at least 4 to 8 weeks to see the benefits."

10 / 10
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  • Ash...
  • September 10, 2016

Zoloft (sertraline) "I have OCD & PTSD. Zoloft is the only medication I've been prescribed. I have been taking it for 3 months, but am overjoyed at the results. I started at 25 mg. It took a month to start working. The first thing that I noticed was that I didn't feel as depressed anymore, and I lost the urge to do most of my compulsions. I am now taking 50 mg and barely have any anxiety anymore, and intrusive thoughts do not bother me anymore, though I do frequently have nightmares similar to the intrusive thoughts I used to have. I also have headaches and occasional diarrhea, but the benefits far outweigh these minor inconveniences."

10 / 10
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67 Report
  • Blair...
  • June 29, 2015

Zoloft (sertraline) "I began taking Zoloft four months ago after being diagnosed with OCD, which I have suffered with for probably 15 years. I started with a dosage of 25 mg and experienced quite a bit of nausea for the first few weeks. I also dealt with a spike in anxiety, which I combated with Clonopin and relaxation techniques. My psychiatrist slowly increased the dosage to 150 mg over the past few months. During that time, with the addition of psychotherapy, I began to slowly recognize that my symptoms were decreasing. It has become much easier to recognize my intrusive thoughts as OCD, and to say 'no' to the multitude of rituals that I engaged in on a daily basis. In fact, since I have reached 150 mg, my anxiety and other symptoms have almost disappeared."

10 / 10
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74 Report
  • Anonymous
  • Taken for 1 to 2 years
  • October 15, 2021

Zoloft (sertraline) "It has taken me 2 years to have the courage to write this post. I was incredibly desperate to find help for significant OCD (scrupulosity form mostly, among others), and at my worst was desperately combing this page looking and hoping for answers. It was terrifying. I had indications of OCD throughout my life but had some triggers 2 years ago that left me spiraling. I was very afraid to take a high dose of Zoloft and should have increased much faster. My first therapist did not get it. I then found someone on the OCD foundation website who was a godsend. The combination of working with her on ERP and 100 mg Zoloft has me happier than I’ve ever been. It took about 4 months to see a significant difference. I have virtually no side effects. Zoloft got me out of the thick of it, but my therapist brought me back to my best self. “Overcoming Intrusive Thoughts” was also a great read. Please know it’s a tough road but it’s worth it and you are not alone. You can get through this."

10 / 10
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31 Report
  • Nocd
  • Taken for 1 to 6 months
  • November 23, 2022

Zoloft (sertraline) "I am on 200 mg of Zoloft and I had no worse side effects (compared to lower doses) but helped me more with my OCD thoughts. Yes. Night urination and less sex drive is true but not a big deal. If will be needed I'll go up to 400 mg. 200mg is maximum FDA approved for MDD. For OCD your doctor can take you up to 400 mg. Wish I never had OCD. Stupid pure O total waste of time thoughts fill us with fear and anxiety."

9 / 10
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21 Report
  • Sam
  • Taken for less than 1 month
  • September 18, 2020

Zoloft (sertraline) "Zoloft works pretty well after being on it for nearly a month. In the first two weeks, my mood was bad, and I had very jittery hands and whatnot, this was while I was on a 25mg dose. Then I started to feel slightly better, then upped the dose to 50mg. During this time, I felt the side effects all over again, and I believe now it's just leveling off, and I finally feel a shift again, where I am able to appreciate things more, laugh more, etc. The obsessive thoughts aren't gone, but they are way more manageable, and I don't ruminate on them nearly as much."

8 / 10
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37 Report
  • Average...
  • Taken for 1 to 2 years
  • September 3, 2021

Zoloft (sertraline) "I started Zoloft after a period of stress led to me having a mental breakdown that led to weeks of crippling existential angst and depression. Before this, I was studying at university and was extremely into bodybuilding and fitness. I would describe myself before this first breakdown as being a very happy person who definitely was highly strung but nothing severe or that I would classify as anxiety. After this mental breakdown occurred, I was left devastated. I lost 10 kg of muscle, and I couldn’t eat or be bothered to look after myself. I started Zoloft at 50 mg reluctantly and continued to live but barely existing. After a horrible couple of months of side effects, I just woke up one morning feeling normal. The things that plagued my mind just disappeared and didn’t matter anymore. I felt myself again. This drug allowed me to save my life."

9 / 10
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30 Report
  • duder...
  • March 29, 2017

Zoloft (sertraline) "I started on 25 mg and went up to 50 mg/day for a relapse of pure-obsessional OCD. It took about a month for it to start working, but this drug, in combination with learning the principles of Exposure Response Prevention Therapy (ERP Therapy) - a type of Cognitive Behavioral Therapy (CBT), have allowed me to regain control of my mind. The depression that came with the relapse vanished in two weeks, anxiety and intrusive thoughts slowly dissipated/reduced in intensity about a month afterwards. I feel normal again, and I couldn't be happier. If you're one of the unlucky folks who have been blessed with OCD, give sertraline (Zoloft) a shot. Just make sure to combine it with therapy, otherwise, it won't be as effective."

9 / 10
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58 Report
  • moww
  • January 30, 2013

Zoloft (sertraline) "I have OCD/general anxiety and depression as a result. I was considered a very severe case. A few months after the worst time in my life, I am happy and healthy. I am managing anxiety/OCD a lot better and I have VERY rare bad days. I have been taking Zoloft with therapy for a little over six months. I experienced about a week of side effects (nausea, increased anxiety, fatigue) but over quickly. I get away with taking 50 mg. Apparently the most common side effects are weight gain and loss of interest in sex. I am happy to say I am experiencing NEITHER! I gained a little bit of weight (5-10 lbs) in the last few months, but I lost about 30 lbs before Zoloft due to anxiety-linked anorexia. Now without depression/OCD, I finally have my sex drive!"

9 / 10
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79 Report
  • Finally...
  • Taken for 1 to 2 years
  • November 6, 2015

Zoloft (sertraline) "I have always struggled with intrusive thoughts that manifest in various forms (obsession with being 'perfect', eating disorders, social anxiety, etc.). But for several years of my adult life, I wanted help so badly because I was miserable... Just completely uncomfortable and restless with anxiety that would come and go but stayed with me much longer than it would stay away. I tried talking to local counselors and was very disappointed, as they were not educated on OCD. After a year of no luck with counselors, I found one (university counselor) who knew what I was going through and how to help me. Life is so much better! I started at 50mg and currently take 200mg."

10 / 10
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  • jesssse
  • November 8, 2015

Zoloft (sertraline) "Zoloft is an excellent medication for treating obsessive-compulsive disorder, depression, and anxiety, all of which I have. Ever since I started taking it, I have been so much happier and worry-free. However, I am 24 years old, and I enjoy going out to the bar with my friends. Let me tell you, if you want to drink on this medication, be advised that it will completely cancel the drug out. Every time I drink, I have severe anxiety the next day. But other than that, I would recommend this drug."

8 / 10
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63 Report
  • ocdmu...
  • March 7, 2012

Zoloft (sertraline) "I have been taking Zoloft now for 7 years. I felt almost instant relief for about a week after first taking it, only to come crashing back down again. I guess it was some kind of placebo effect. But sticking it out and upping my dose to 200mg a day, after about six weeks I felt so much better. I could function, and instead of my mind having hundreds of things running through it, I could focus on the one thing and work through my problems. My only side effect was an upset tummy, but that passed. I'm grateful for this medication. It saved my life."

9 / 10
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80 Report
  • Anonymous
  • August 13, 2008

Zoloft (sertraline) "I've been on Zoloft (50mg) for 18 months and the results are wonderful. I had a hard time letting kids be kids, everything had to be done my way or I'd lose my temper, and I dreaded going to social events - I'd much rather stay at home by myself with a drink. Not only is family life better but my outlook on life is better as well. I no longer fret over the little things. Heck, sometimes I don't even fret over the large things."

10 / 10
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  • rchip...
  • Taken for less than 1 month
  • December 29, 2014

Zoloft (sertraline) "I was offered sertraline (Zoloft) after a relapse of generalized anxiety disorder, which brought with it a severe case of pure-O intrusive thoughts of the harm variety. These thoughts were ruining my life and making me depressed. I was prescribed 50 mg per day. The first three days were hell, with a huge increase in fatigue, depression, and intrusive thoughts. I almost gave up, it was that bad. I was using diazepam 2 mg in those first three days and thought they weren't playing nice with the Zoloft, so I stopped them. I saw instant improvement after doing so. Now I am seven days in and have had the best day ever. My intrusive thoughts are far fewer and far easier to simply dismiss. I'm amazed."

9 / 10
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64 Report
  • noire
  • Taken for 1 to 6 months
  • April 5, 2020

"Sertraline can make you feel on top of the world, or want to hide in the darkest depths of your mind. I struggled with OCD for 8 years (early signs at 11, bad at 15, now 19), and along with anorexia and high-functioning autism, I hid in my brain and let it demonize everything that made me happy. I was losing myself. Been on it for 2 months. 50 mg was numbing to begin with and felt distant. Had the nausea and insomnia. 100 mg was the worst. I felt so irritable and annoyed and hot and stressed. 150 mg was amazing, I felt so much better about myself and my OCD thoughts were massively reduced. 200 mg reduced thoughts further, but the insomnia is bad. Without sleeping tablets, I can't sleep, with them, I'm lucky to get more than 4 hours a night. My advice is to push through it, don't focus on how sh*t it makes you feel in the moment, think about your life free from OCD, make that your goal, your motivation. Hope this helped and that you all find peace one day :)"

10 / 10
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35 Report
  • Jojo
  • June 21, 2018

Zoloft (sertraline) "Zoloft really changed my life for the better. I was struggling with intrusive thoughts and rituals as part of my OCD, and while Zoloft didn’t completely eradicate all that, it really helped me combat it. 150 mg gave me some minor side effects, 100 mg is great."

10 / 10
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45 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.