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Semaglutide and Nausea: What Users Say (Page 2)

Brand names: Ozempic, Rybelsus, Wegovy

Reviews for Semaglutide

Commonly mentioned side effects
  • Mom...
  • Taken for 1 to 6 months
  • December 29, 2021

For Weight Loss (Obesity/Overweight) "Just took my last injection of month 5, 1.7. I have lost about 25-30 lbs along with 3-5 days a week at the gym. Definitely curbs your appetite. The nausea is very real! Each month I thought it would get easier. It never does. A couple times I puked for hours. Lots of belching. In the beginning, a little constipation. The first day or 2 after the injection, you can feel fatigue. It works for weight loss if you can tolerate the nausea. This will be my last month. I have a 6-month prescription but I can’t deal with the nausea anymore."

8 / 10
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  • Mar...
  • Taken for 6 months to 1 year
  • February 1, 2021

For Type 2 Diabetes "I started taking Ozempic in June 2020, initially lost 20 pounds by August. Total of 30 pounds so far, last 10 have been a lot slower. I went from 186 pounds to 156 pounds. A1c went from 6.5 to 5.6. Minimal side effects include occasional nausea and constipation. Started using Miralax, which has helped. Side effects I have experienced are worth the benefits. I consistently wake up with glucose levels in 80-90 range, never out of the green zone on a glucometer. I cannot overeat. If I do, I feel ill or get heartburn, so I have learned my lesson. I am really happy with this medication."

10 / 10
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325 Report
  • Ser...
  • Taken for 1 to 6 months
  • March 1, 2022

For Weight Loss (Obesity/Overweight) "Seven weeks in and it’s great! I’ve lost 12 lbs already. I don’t have that many side effects to discuss, but you do have to be careful what you eat and how much you eat. If you try to eat too much food that is high in fat or high in sugar, you will not feel well. You do have to listen to your stomach as you get full very quickly, if you push it you could become queasy. As long as I pay attention to this, I feel fine and have little side effects. I do inject it in my thigh as I have read that it reduces bad side effects. Perhaps that’s the key."

10 / 10
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Frequently asked questions

  • Gum...
  • Taken for 1 to 6 months
  • February 28, 2020

For Type 2 Diabetes "I’ve been on Rybelsus since 1 December at a dose of 3 mg. January 1, I started 7mg. I don’t like taking medication and was scared of this medication due to other reviews I have read. I am very pleased with the outcome. I lost 5 lbs with very little exercise. My side effects were nausea and loss of appetite. Nausea only occurred when I ate junk food and sweets. A1c down from 7 to 6.2. Plus, I do not take any other meds for diabetes. Hope my review will help others. February 28."

10 / 10
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318 Report
  • Lyn...
  • December 22, 2020

For Type 2 Diabetes "I took one dose of Ozempic and I have been sick ever since. Diarrhea, vomiting, nausea, stomach cramps, and a little dizziness. This is terrible, will never use again. Can someone tell me how long these symptoms last?"

2 / 10
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298 Report

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  • Ail...
  • Taken for 1 to 6 months
  • January 4, 2021

For Cardiovascular Risk Reduction "I went on Ozempic for weight loss after being told by a friend of mine about it - she started at 280 lbs and lost 60+ pounds. My whole life I’ve always been about 130 pounds, and then I rapidly gained 50 pounds within about 2 years. I started taking Ozempic at 182 pounds (I’m 5’4) and 6 months later I am down 25 pounds and continuing to lose. I could not recommend this drug more. It INTENSELY reduced my appetite and obsession over food. Aside from some occasional nausea (maybe once every 2 weeks), and some diarrhea, nothing that I can’t handle, the drug has been pretty great. This is only my experience though!"

10 / 10
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  • Koo...
  • May 1, 2021

For Type 2 Diabetes "I have been taking Rybelsus for 6 months. At first, I was nauseous and had bad sulfur burps, but it went away. My A1C is the best it's been in 9 years. I have had a hard time treating my diabetes, as most other oral medications and daily injections just made life harder. Now, my numbers are 6.7, and I have lost a significant amount of weight, 335 lb to 285 lb, with minimal effort. It definitely suppresses my appetite. I've read you can only lose a few pounds, but I feel like a lucky one."

10 / 10
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More FAQ

  • She...
  • Taken for 1 to 6 months
  • September 4, 2020

For Type 2 Diabetes "I've been on Ozempic for 8 weeks. At first, I had side effects of a lot of nausea. Now, I wake up cold and clammy the last week and very anxious. Overall feeling unwell. Wondering if anyone else has experienced this?"

3 / 10
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259 Report
  • Chr...
  • Taken for 1 to 6 months
  • July 11, 2021

For Type 2 Diabetes "I suffered from - Loss of appetite - Exhaustion - Nausea - Vomiting (once a week, usually 2 days after my injection) - Low blood sugar events (probably caused because I just had no appetite). When I spoke to my pharmacist, she encouraged me to try to hang in there, telling me it would get better, and it finally has. I was not expecting it to take over 3 months though. My readings are all good, and I've lost 28 lbs, so there were benefits to sticking it out, but it was hard. I had decided that I would continue to take the medication until my next appointment, and if things were still bad, I would tell the doctor that I no longer wanted to use it. Things are better, and my appointment is next week."

5 / 10
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213 Report
  • Ama...
  • Taken for 6 months to 1 year
  • December 16, 2021

For Type 2 Diabetes "Listen to me, Ozempic will change your life, but you cannot eat synthetic sugar at all. I had severe Hashimoto's, PCOS, insulin resistance, and severe diabetes symptoms. HbA1c was high, all cholesterols were high despite the healthiest of diets. My numbers cleared from severe to perfect in 1 month! I had full-body swelling, severely cracked ankles, swollen feet, neck, legs, major hair loss... a nightmare. I began taking Ozempic. I was very sick. It made me extremely nauseous. I got severe diarrhea, but let me tell you, I lost 17 pounds of water weight in one month. My doctor couldn’t believe it. In four months, I lost 40 lbs. The nausea was mild to severe the entire time, but the results were borderline insane. It reset my metabolism, took all of the inflammation away from my joints, neck, back, my feet completely healed within one month. It’s barely believable. I spent two months on 0.25 and increased to 0.5 once a week for ten more months. High praise!"

10 / 10
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  • Lem...
  • Taken for 1 to 6 months
  • February 1, 2021

For Type 2 Diabetes "Honestly, I am so impressed so far with these meds. My weight had been creeping up due to insulin resistance (which itself makes it harder to lose weight) and PCOS. My doctor recommended I try this in conjunction with a very low carb and calorie diet. I started with a half dose of 0.25mg once a week injection and then after 2 weeks up to 0.5mg a week. So far in 6 weeks, I’ve lost 15cm from my waist and 9cm off my hips, and 5cm off my bust. I have been eating light and easy, roughly 1000 calories a day. Haven’t weighed myself yet as I’d prefer to see the difference in cm. This medication makes me feel a little nauseous the first day or two after my shot, but after that, I never feel hungry. I can quite easily eat a super small portion and feel full! I drink about 2L of water a day and do about 8000 steps at my job. It really has been great and so much cheaper than Saxenda, which was another one I was considering. Hopefully, I continue to lose weight!"

10 / 10
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  • Sks...
  • Taken for less than 1 month
  • May 25, 2023

For Weight Loss (Obesity/Overweight) "I never leave reviews and rarely have side effects from medication. However, after one injection on the lowest dose, I am so beyond sick. Two days after my injection, I got a migraine followed by extreme vomiting for 4 days, chills, nausea, and a trip to the ER. This medication made me so unbelievably sick, it is like I've been poisoned. I have missed 4 days of work and am so weak. Living on Pedialyte and numerous nausea medications. Please be so careful. I was so hopeful and had no idea this would happen to me."

1 / 10
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  • RNi...
  • Taken for 1 to 6 months
  • May 4, 2022

For Weight Loss (Obesity/Overweight) "Wegovy does work, problem is... I feel like dirt all day long. I'm fatigued, nauseous, and even the smell of food makes me vomit. My heart races, and I'm quite dizzy. I lost 55 lbs. Do I look good? Yes. Do I feel good? No. I'm down to 153 lbs now. It's time to stop this medication."

6 / 10
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  • Jen...
  • November 29, 2020

For Type 2 Diabetes "My doctor put me on Rybelsus in March/April 2020. I will admit the nausea was pretty bad for about the first month, but I stuck to it because it was really working well on my blood sugar. Since I started, I have lost 42 lbs! I have not been dieting, but I do have some outdoor projects that required physical labor, like shoveling dirt, clearing brush, moving stones, etc. The nausea only comes back when my sugar is low and I really need to eat. I don’t even get a growling stomach anymore. I would recommend Rybelsus to anyone looking to manage their blood sugar and lose some weight."

10 / 10
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  • sou...
  • Taken for 1 to 6 months
  • March 23, 2023

For Weight Loss (Obesity/Overweight) "I am in my sixth week of Wegovy (4 weeks at 0.25 and now 2 at 0.5). I am a male in my early 50s, 5'9'' with a lot of weight to lose — about 120 pounds. In the first month, I experienced no side effects apart from reduced appetite and lost 10 pounds. I had just begun dieting when I started — nothing extreme, just eliminating the worst offenders: sugar, not eating after 6pm, and portion control. I have already lost 6 pounds this month. I have experienced some mild nausea this month on the 0.5 dose, nothing close to vomiting but definitely present, especially the two days after injection. Haven't had negative reactions to specific types of food like others have had until yesterday. Had some Korean BBQ and was burping garlic all night with some intestinal discomfort - so I guess that's a no go. I am considering holding at this dose before going up again. As long as the weight loss is happening at this rate, I am not keen to risk greater side effects."

9 / 10
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108 Report
  • Anonymous
  • Taken for less than 1 month
  • February 24, 2023

For Weight Loss (Obesity/Overweight) "Horrible experience. I only took 2 dosages because I had difficulty functioning with headaches, eye pain, nausea, dizziness, and overall feeling awful. The additional issue is I've been off the drug for a week and can't get rid of the symptoms. I'm nauseous every day, with headaches, and dizziness. How long until all of this goes away?"

1 / 10
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119 Report
  • Ami...
  • Taken for less than 1 month
  • February 13, 2022

For Type 2 Diabetes "I was very frightened after reading the reviews. I am 52 and had gained from 130 pounds to 158, the most I have ever weighed in my life. Started the 3mg 3 weeks ago and have lost 10 pounds with no side effects other than occasional slight nausea. My appetite has decreased but for the better. I am walking 3 miles a day and eating very healthy. Stopped drinking soda, now only flavored water. I consider this a miracle. Never lost weight this quickly. Happy as heck. Will continue the 3 mg and recheck A1C. So far this rocks. If it enables me to get in control of my eating and lose to a healthy weight to better my overall health, then I call it a huge success. Love, love, love it!"

10 / 10
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143 Report
  • Can...
  • Taken for 1 to 6 months
  • November 29, 2020

For Type 2 Diabetes "When I first started the 3mg of Rybelsus, the nausea for the first 3 weeks was nearly unbearable. However, like magic, around day 21, it stopped. I don’t feel as full as I did at the beginning now that I’m starting my second month of 7mg. However, I continue to lose weight with diet and exercise. If you’re struggling at the beginning - hold on for 30 days - it might pass like it did for me!"

9 / 10
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175 Report
  • Ski...
  • Taken for 1 to 6 months
  • May 31, 2020

For Type 2 Diabetes "My husband began taking Ozempic for his Type 2 diabetes several months ago and experienced minimal unpleasant side effects. His food consumption is down approximately 2/3 (no more 'first breakfast and second breakfast' and 'first dinner and second dinner') and he has been able to reduce his diabetes medications. He has been steadily losing excess weight. A bonus is the chronic loose stools he used to suffer have been eliminated. I started taking Ozempic for my Type 2 diabetes 6 weeks ago. My food consumption is down significantly and I've been able to discontinue all other diabetes medications. I've had some slight nausea and a mild bit of constipation, both of which have been easily alleviated through dietary changes (much smaller meals, more fiber and more spicy food). We absolutely love this medication."

10 / 10
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187 Report
  • fin...
  • Taken for 1 to 6 months
  • January 17, 2022

For Weight Loss (Obesity/Overweight) "Took it for 8 weeks, made it through the 2nd titrated dose and couldn't handle it anymore. Nausea, gas, bloat, constipation, diarrhea, and it was worse at night while lying down. Never improved, but actually got worse by week 8. Not sure how anyone makes it to the full dose. Also did not drop a single pound. There were days I only consumed 600 calories and still felt awful. I read another review very similar and agree that you absolutely cannot eat anything spicy. Bland food days were better but there are not enough antacids and constipation meds in the world to make me want to lose 20 pounds this badly. Took my last dose 10 days ago and am still dealing with residual GI upset. Hope physicians are more forthcoming about the side effects and do not tell patients they happen but subside in a couple of days - they do not."

1 / 10
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152 Report
  • Nw2...
  • Taken for 1 to 6 months
  • June 20, 2021

For Type 2 Diabetes "Started April 1, 2021, on Ozempic low dose. 3-week intervals it was increased. Side effects were constipation (went on laxatives to help), pain in my back (severe), bloating. Week 11 increased to 1mg, the side effects were major bloating, diarrhea, sounds in my stomach (crazy), nauseous, feeling under the weather. My appetite has decreased to the point that I only eat 2 meals a day that are small. My sugar levels have decreased from 7.1 to 5.2 A1C. I’ve noticed that I have been kept awake some nights like I’m nervous for some reason. In the first 3 weeks, I’ve lost 15 pounds. Haven’t checked since I want to wait but can feel a difference. The pains in the stomach are really uncomfortable, and the bloating I will try gas-x for relief. When I try to eat more than I should, my body tells me that I’m full. If I go beyond that point, I get severe pains in the stomach for hours. But depends on what I eat. Going to stay with smaller portions/healthier foods."

8 / 10
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148 Report
  • She...
  • Taken for 6 months to 1 year
  • May 1, 2022

For Weight Loss (Obesity/Overweight) "I began Wegovy in late August '21. I had bariatric surgery in 2000. Menopause, major life changes, and COVID resulted in a 60 lb weight gain over 5 years. It's May 1, and I've lost a total of 81 lbs. My BMI has gone from 38 to 25, and I never got to the 2.4 injection. I had slight nausea and 2 incidents of gastrointestinal uncertainty ('sharts') the first 2 weeks, but nothing after that. I walked 1.5 - 2.0 miles 6 or 7 days weekly, ate a high-protein, low-carb diet, switched to 50/50 Stevia/Sugar as a sweetener, and ceased eating after 8 pm nightly. I feel great, and because of my weight loss, I can delay my other hip replacement. Wegovy gave me a second chance at better health, and I'll continue to use it for maintenance."

10 / 10
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120 Report
  • Mid...
  • August 21, 2020

For Type 2 Diabetes "My health wasn't good, so I fired the nurse practitioner I was seeing and got an internist doctor. Found out my thyroid was almost non-functional, high blood pressure, and my pre-diabetes rate was on a serious climb. 1 year later, I was at the right dose of Synthroid. Doctor put me on metformin and phentermine, and added Ozempic 2 weeks later at 0.25. That was a rough ride, I was nauseated and dizzy a lot! I started at 265 lbs, and every day I would see a pound or 2 come off. As of this morning, I weighed in at 239, and I'm up to 1 mg dose of Ozempic weekly. I take the anti-nausea now just before my Ozempic dose, and that's it. I use doTERRA ginger. A1C down to 5! I'm glad I listened to my doctor and my pharmacist and stuck with it. Anything worth having doesn't usually come easy! I would like to get down to the 160-170 range, I'm 5'11'', and thinner than that, I start to look like Olive Oyl! OH Popeye!"

10 / 10
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173 Report
  • LAD...
  • Taken for 1 to 6 months
  • July 4, 2022

For Weight Loss (Obesity/Overweight) "I took Wegovy for a few months and did, in fact, lose some weight. The side effects are terrible, as so many others have noted here. One thing that they don’t tell you is that the drug slows down the stomach's ability to empty. This is why people feel full and experience reflux, nausea, etc. In my case, the drug not only slowed down my stomach's ability to empty, it permanently paralyzed my stomach muscles, a condition called gastroparesis. The only remedy was to have a neurotransmitter implanted in my stomach, which forces the muscles to move. Do NOT take or first this medication. You could end up like me with a lifetime medical issue. No weight loss is worth that."

1 / 10
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125 Report
  • Tan...
  • Taken for less than 1 month
  • June 18, 2022

For Cardiovascular Risk Reduction "I was so afraid to try this med because of all the bad reviews. I could not survive endless nausea or stomach issues. I just came here to say that I had none of these issues, and it is helping with cravings."

9 / 10
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114 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.