Semaglutide and Loss Of Appetite: What Users Say (Page 3)

• Eri...
• Taken for less than 1 month
• January 4, 2020

For Type 2 Diabetes "I've taken Ozempic for 2 weeks and experiencing severe nausea and decreased appetite upon smelling the aroma of food. I am eating smaller portions since the nausea is severe. As for weight loss - I have to purchase a new scale, but noticed that my shoes seem bigger on my feet, which means I'm retaining less water and bloat. My pants are also looser. I am taking this medication with Metformin, which makes me use the bathroom and assist in my weight loss. I'll update again after week 4/5."

• Wor...
• Taken for 1 to 6 months
• January 28, 2022

For Weight Loss (Obesity/Overweight) "First, I am disabled with Lyme disease and severe fibromyalgia. I gained 20 pounds because I couldn't move for 2 years. I went on Wegovy. I was okay with the side effects (no appetite, a little bit of nausea) until I got to the 1.7 dose. I tried for 6 weeks on that dose. I was the sickest after the dose day for the majority of the week. I could barely eat. I did lose weight: 18 pounds in 4 months. I did no exercise whatsoever. In fact, I'm mostly bedridden. But feeling that ill on top of my constant pain was too much for me. I went down to the 1 mg, and we will see if I can do that. I also take pain meds and a fibro drug (also causes nausea). I have a nausea med called Zofran. You might want to ask for this. The nausea is awful, but really not bad for me UNTIL I started the 1.7 dose. Just couldn't stay on that. Definitely takes off weight. At one point, I ate 800 calories in 4 combined days, it was that bad. You might want to titrate slowly."

• Bro...
• Taken for less than 1 month
• February 13, 2021

For Type 2 Diabetes "Worst feeling and sickness ever after just one dose. Started out with no appetite. The second day after the shot was given, started throwing up after I ate. By the third day, was constantly throwing up. Could not even eat a piece of ice without throwing up. Lost two days of work, and it ruined my Valentine weekend plans. Worst experience ever. Do not recommend to anyone."

• Tan...
• Taken for 1 to 6 months
• September 11, 2019

For Type 2 Diabetes "I’m on Ozempic for weight loss. I started at a small dose for 4 weeks, 0.25, then 2 weeks, 0.5. Now I’m on maintenance, taking 1 mg. In the beginning, straight after the injection, I would suffer from nausea, migraines, and loss of appetite. My side effects have shifted. I don’t suffer from nausea for more than a day, however, I have sulfur gas. It’s horrible. I’m bloated and very gassy. I haven’t lost a ton of weight yet, however, I do think diet is key as I am taking this for weight loss, and so far, yes, my appetite is suppressed. A day or two before it’s time to take the injection, I gain more of an appetite. This stuff is killer expensive, and my insurance doesn’t cover it. I’ll give it a couple more months and see how it goes."

• Sal...
• Taken for 6 months to 1 year
• January 29, 2020

For Type 2 Diabetes "Been on Ozempic for about 8 months. Everything was fine with 25 units. I've had a few bouts of low blood sugar. Dropped a little weight due to loss of appetite, and my A1C is almost normal = 6.7. Anyway, I may have to stop taking it because of the cost. My Part D has a $435.00 deductible for tier 3 drugs with a $42.00 copay. This drug is for rich people only. I'm on Social Security. How can anyone afford this? I'm very upset."

• blh...
• Taken for less than 1 month
• May 31, 2024

For Weight Loss (Obesity/Overweight) "First dose 0.25mg, had slight stomach pain/discomfort. Later that same night, my appetite disappeared. Just seeing a fast-food commercial on TV made me feel nauseous. I thought if that's the worst of the side effects that affect me, then I'll be very happy with that. By the next day, stomach pain and nausea increased. By 4:00 am, BAM! Diarrhea, severe stomach pain, projectile vomiting, headache, chest pain, severe itching mainly on the palms of my hands and arms. I truly thought 'this must be what it feels like to be poisoned!' I was scared. It is now the next day and I feel fine. A little tired from lack of sleep from feeling so sick. I think I will do my second dose next week...but I'm quite nervous of a repeat of feeling like I was dying from the stomach pains and vomiting. Will I continue with this drug?...jury is still out! On the positive side, I've already lost 5 pounds; but of course, I can't & don't want to eat, too much nausea and vomiting."

• ERa...
• Taken for less than 1 month
• August 14, 2019

"After having my last child, I had my thyroid removed and ended up with hypothyroidism. I gained about 60 lbs within a year from 190 lbs to 252 lbs, and I was 190 lbs just after I had the baby! I am not diabetic. My Endocrinologist increased my dosage of Levothyroxine to 225 mcg and started me on Ozempic. I've taken 3 doses of Ozempic (beginning week 3 today) at .25, and I'm already down 9 lbs. Zero appetite, no side effects. Just have to stay hydrated."

• Bub...
• Taken for less than 1 month
• December 31, 2019

For Type 2 Diabetes "I started Ozempic Dec 4 with 0.25 the first and second week and 3rd & 4th week .05. I lost 6 pounds. The only side effects I’ve had were lack of appetite (but I do eat, but a third of what I used to), full stomach, diarrhea just 3 times in 4 weeks, and today a sudden onset of blurry vision. My eye doctor squeezed me in today and found nothing wrong. I told him I was taking this medicine and a side effect was blurry vision. It may just even off in a few days, nonetheless, I have a call into my primary doctor to make him aware and see his opinion. So far, that’s about it. I will continue to take this unless I’m told otherwise. It’s really keeping my glucose below 100 daily."

• JRo...
• Taken for 1 to 6 months
• October 29, 2019

For Type 2 Diabetes "Within 2 weeks after moving from the starter dose of Ozempic to 0.25 to 0.5, I began having vomiting in the wee hours of the morning, with increasing intensity, nearly every night for the last 2+ weeks. The last 4-5 have been really rough. I also take metformin 500 and glimepiride 2, both AM and PM. This weekend, I went down to the Ozempic 0.25 dose, but Sunday and Monday nights were both awful bouts of vomiting. (No diarrhea at any stage with Ozempic; occasional nausea during the day, very decreased appetite.) Is anyone else having this bad and persistent vomiting? Thanks and good luck."

• cra...
• Taken for 1 to 6 months
• June 24, 2019

For Type 2 Diabetes "I was okay on the 0.25 mg and 0.5 mg doses of this drug, Ozempic. Then, five weeks ago, I upped to 1 mg as planned. About four weeks ago, my mood changed, and I started to get pain in my joints and bones. Achy all over and no energy. Two weeks ago, the abdominal pains, gas, diarrhea, and those awful sulfur burps arrived. I feel absolutely awful, and the doctor is convinced it is this drug increasing. No appetite either and feeling sick. Was loving the drug in the beginning, but now I feel like I've got permanent flu!"

• GEL...
• Taken for 1 to 6 months
• July 15, 2024

For Type 2 Diabetes "Find it difficult to take as it makes me quite nauseous. I have been taking it at 12 noon one hour before my lunch. I started off taking it at 3 a.m. when I usually awaken for a visit to the loo, and this lowered my blood glucose very well in the early morning, but then I was not getting enough sleep. However, I could not cope with the side effects and stopped taking it. Since reintroducing it, my morning glucose readings have been in the region of 12-15 mmol/l, which is not great. However, I am on 7mg of Rybelsus. I cannot drink more than 2 glasses of wine, which is good. Also, it has reduced my appetite substantially, which is also good, and I lost 3 kg in weight when I started taking it."

• Liz...
• Taken for 1 to 6 months
• January 21, 2023

For Cardiovascular Risk Reduction "Ozempic has done nothing to help me with Type 2 diabetes nor weight loss. I have some stomach discomfort and some loss of appetite. My blood sugar levels are just as high with Ozempic as before taking Ozempic."

• Eda...
• Taken for 1 to 6 months
• February 6, 2020

For Type 2 Diabetes "So I have been on Ozempic for 5 weeks. I am tired a lot. Not sure if this is the drug or my poor sleep, but now that I see others are tired a lot, it makes me wonder. I have nasty burps a lot. I started on a dose of 0.25 for 4 weeks. I had a lot of low-level nausea, but not too bad except for one day. Then last Sunday, I took the higher dose of 0.5, and I was okay on Sunday and Monday, but Tuesday the nausea was horrible, and I had explosive diarrhea all day to the point I had to take Imodium, and I got my doctor's office to prescribe an anti-nausea med, Zofran, which helped a little. The next day, less nausea, and today is Thursday of that week, and I still have the burps and more BMs than I would like, as well as a lot of gas. I know I have lost weight just by how my clothes fit. I have very little appetite. Not sure if the pluses outweigh the minuses yet. I am probably going to try one more week and see how I feel. It has had a modest impact on blood sugars. I have been using less insulin."

• Bai...
• Taken for less than 1 month
• July 3, 2019

For Type 2 Diabetes "At first, I had a brief overwhelming bout of nausea that passed. Decreased appetite definitely had me losing weight, but after the second injection, the nausea got much worse! Plus, I had diarrhea/vomiting, and it just got worse daily. I had to discontinue. Now it's been a month later, and I'm still having nausea and diarrhea. Horrible experience for me."

• Dia...
• Taken for 1 to 6 months
• December 20, 2024

For Type 2 Diabetes "Enjoyed a weight loss of 1 kg per week over a period of 2-3 months. Suffered: loss of appetite and taste for over 5 months. After about 3 weeks of injections, I began to have chest and throat pain about 24 hours after each injection. The first lasted about 10 minutes (I thought similar to a heart attack), but then they became longer and lasted 30 mins each time. I then stopped using Ozempic and consulted a cardiologist who reassured me my heart was good. I had no desire to continue the injections."

• All...
• Taken for 1 to 6 months
• March 15, 2023

For Weight Loss (Obesity/Overweight) "I took 4 shots of .25 Wegovy. The first shot had no side effects and no problems. The second shot was a little different. Mild upset stomach starting about 24 hours afterward with some stomach pain. This subsided within the third day. My appetite was suppressed, felt fuller for longer. In the third shot, I had no appetite with stomach pain that lasted two days, and also felt as if I were going to pass out. I drank orange juice and ate saltine crackers with peanut butter, which helped. The last .25 shot of Wegovy… I had lost 12 pounds by this shot. But within a day, I was projectile vomiting, upset stomach, extreme pain in my abdomen, chills, and dizziness. I was taken to the emergency room. I was diagnosed with colitis that had gone to sepsis. The doctor explained a side effect from Wegovy may cause gastrointestinal problems. Wegovy attacked my colon and in turn, sepsis formed. I will not continue this shot. So many side effects go with it. It does curve your appetite, but I would be very cautious."

• Nuk...
• Taken for 1 to 2 years
• December 13, 2019

For Type 2 Diabetes "I've been on Ozempic for a year. Taking 1.0 mg. Pros: Have lost 40 pounds. A1c went from over 8 to 6.2. Have stopped taking insulin and glyburide. All positive. Cons: Days of constipation followed by hours of diarrhea. No appetite. Cost is way out of control. But I'm satisfied enough that I'm still on it."

• I...
• Taken for less than 1 month
• November 1, 2021

For Type 2 Diabetes "I rarely ever have side effects from any drugs that I have taken before. After my second dose, I began extreme side effects of stomach pain, bloating, sour belching, flatulence, diarrhea, zero appetite, and indigestion. These symptoms have not gone away after 10 days of discontinued use. It definitely lowered my daily sugar levels. You can use this medication if you are okay with feeling like death."

• Geo...
• Taken for less than 1 month
• February 23, 2022

For Type 2 Diabetes "Been on Rybelsus 3 mg for 16 days. Sugars have improved somewhat already, and weight down about 5 pounds, unexpected. BUT, no appetite, stomach feels full all the time, hard to even drink enough water each day because stomach so uncomfortable. Constipation that is not very responsive to Miralax. Cold hands. Some nausea. More heartburn than usual. Increased fatigue. And the worst is: dizziness and/or vertigo and a feeling of weird fullness in my head along with tinnitus. What the heck? Given the high cost, and that I've all these effects even before going on the 7 mg dosage, I don't think it's worth it."

• Ryn...
• Taken for 1 to 6 months
• February 9, 2022

For Type 2 Diabetes "I started on this medication in December. It immediately lowered my blood sugar, however, it made me very nauseous and have a loss of appetite. It is now February, and I have lost 15 lbs. I still don’t have much of an appetite these days. I find eating very light meals 2x a day helps a lot. Trying to stick with it."

• Poi...
• Taken for 1 to 6 months
• January 18, 2019

For Type 2 Diabetes "Started taking this med about a month ago and not sure I will stick with it. After 2 weeks, stomach cramping and some constipation started, but the worst of it all is the stress I am having with horrible sulfur burps. The smell is so horrible that even the smallest of burps can linger in a room for minutes, and you can really clear a room. I have had to have Febreeze Air Fresheners nearby at all times. If I feel a burp coming in the middle of the night, I literally run to the bathroom as it is really very unpleasant for my spouse and it really embarrasses me even after 27 years of marriage as it’s that bad! We just lowered my dose to 0.25 mg, but if the sulfur burps remain, that will seal the deal and I will stop it. Have lost 10 pounds over the month too as appetite is shot, and I’m not sure that’s really the best way to lose weight if you can barely eat at all."

• Chr...
• Taken for 1 to 6 months
• February 24, 2020

For Type 2 Diabetes "I started taking this in August. It left me with a terrible taste which I could not get rid of. I was changed to the lower dosage, and it didn’t seem too bad, but it made me feel awful. Loss of appetite, I could eat a full bowl of soup. If I went out, I had to bring half my meal home. After going back to the doctor numerous times, they have taken me off it and back to Victus, which makes me feel a lot better. I no longer have that awful taste and feel better. I did get tonsil stones, which I have never had before, and I’m pleased to say they have now gone."

• Kay...
• Taken for less than 1 month
• March 11, 2022

For Cardiovascular Risk Reduction "Started Ozempic 0.5 mg a few days ago to help me lose weight, a bit of nausea, and diarrhea, and I lost my appetite for food. I feel it is really working. The only thing is with the side effects, hope they don't get worse."

• Car...
• Taken for less than 1 month
• May 10, 2019

For Type 2 Diabetes "I was put on Ozempic for insulin resistance and PCOS (polycystic ovary syndrome). I take my 3rd dose of 0.25 tomorrow. The 1st week taking it, I had immediate loss of appetite and mild to severe nausea. The struggle with constipation is still ongoing. I would say overall I just felt yucky. Took 2 doses before my body mellowed out and the nausea went away. I find big meals overwhelming now, and I recommend eating healthy snacks more frequently throughout the day (due to loss of appetite). Will up dose to 0.5 in 2 weeks and am nervous that the side effects will return, but hoping not. So far, I have lost 3 lbs, but my weight fluctuates up and down 5 lbs regularly, so not sure yet if it is the Ozempic or not."

• Anonymous
• Taken for 1 to 6 months
• January 22, 2022

For Type 2 Diabetes "Started on 0.25 for 4 weeks, then increased to 0.5. Reduced appetite, nausea, constipation, feeling like food just got stuck. I lost over 2 stone. Then started being sick every day, not eating or drinking, every time I did, I was sick. Then I was rushed into the hospital with severe diabetic ketoacidosis. One week after being out of the hospital and recovering, never using this medication ever again. Not worth risking your life."