Semaglutide and Fatigue: What Users Say (Page 4)

• doi...
• Taken for less than 1 month
• June 21, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I am on my 3rd week of Wegovy. So far, the only side effect I have noticed is fatigue. Seems to be worse in the morning, but it's not a big deal at all. My kids keep me awake and busy. I lost 3 pounds in the first week and nothing in the second week. I just took my 3rd dose today and hoping to lose another 3+ pounds this week."

• Big...
• Taken for 1 to 6 months
• May 23, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I started Wegovy (2.4 mg) 5 months ago, weighing in at 417 lbs. Today I'm down 82 lbs. Not bad for no exercise and extreme dieting! Wegovy is NOT for the weak! My first dose almost canceled me completely out of the plan! I experienced severe nausea and vomiting the first 3 days, accompanied by fatigue. I felt horrible, but I chose to stick it out after I stepped on the scale and saw amazing results! After the first month, my vomiting stopped, however, if I ate anything that didn't agree with me, it would come up. I still experience nausea, for which I take Zofran to help keep it to a minimum. The most important thing I love about Wegovy is it makes me think about what I'm going to put in my mouth and if I'm even hungry. I have to remind myself to eat a little something, but most of the time I'm not hungry at all. Most of the time, I'll make a plate and only take a few bites, wrap it up for another time. If you are serious about losing weight, Wegovy is the way to go!"

• Cat...
• Taken for 6 months to 1 year
• March 8, 2023

Semaglutide for Type 2 Diabetes "I've been on Ozempic 0.25 mg since last March. Had a lot of stomach problems for the first 3 months and stopped for a month to calm my stomach. Lost 16 pounds in the beginning, but that has come to a standstill. I have noticed, besides stomach issues, mood swings, mild depression I didn't have prior, fatigue, and still ongoing stomach issues. I will probably stop. While it notes there are cardiology benefits, for me, it's just not worth the side effects. My advice is to make sure you keep in touch with your doctor and tell them how you are feeling."

• ric...
• Taken for 1 to 6 months
• March 25, 2023

Semaglutide for Type 2 Diabetes "I have had terrible side effects from this medication. My legs have swollen to the point of impaired walking, trouble raising either leg to use the shower/tub, and am unable to stand for very long. Shortness of breath, difficulty retaining breath, higher blood pressure, and general fatigue. As for benefits, I really have not noticed any as yet, been too busy coping with the new problems."

• Pea...
• Taken for 1 to 6 months
• February 21, 2023

Semaglutide "I underwent lap band surgery several years ago and am currently taking Ozempic. If given the option, I recommend choosing Ozempic over lap band surgery due to their similar side effects. However, if it is possible to manage diabetes and weight with an alternative medication, I suggest doing so. It's important to administer the injection in the thigh, as other injection sites tend to cause worse side effects. The side effects of Ozempic are persistent and severe, and unfortunately, they are unpredictable. One week you may experience minimal side effects, while the next week, at the same dosage, the side effects may be so severe that you will need to miss work. Ozempic causes extreme fatigue, unlike any other fatigue I have experienced. My eyes struggle to stay open. Additionally, I have suffered from intense constipation for two weeks with minimal relief from laxatives, followed by a few days of uncontrollable diarrhea and acid reflux. I no longer enjoy food; it no longer tastes good, and fruit or tea is no longer refreshing or soothing. I believe there must be a balance between enjoying food and weight loss."

• Kat...
• Taken for 2 to 5 years
• October 10, 2024

Semaglutide for Type 2 Diabetes "I have been on Ozempic for Type 2 diabetes. Was overweight as well, I am 4'11 and had ballooned to over 170 pounds. I was taking medicine for blood pressure, anxiety, depression, you know, all the things. I started in March 2022. My A1c was 7.9. Today I am down to 105 (hold up, that is normal for my height). No more high pressure. Beginning, I wasn't sure I would get past the nausea, but I fought through it, and yes, it does go away. I have been on stool softeners for a while, so I have never had any issues going to the restroom. My A1c is 5.4 now. I don't feel good, though. I can't put my finger on it, but I am severely exhausted and fatigued. I will not trash this medicine because I think it works as it should and has been amazing for diabetics. I just wish I didn't feel like poo all the time. The side effects do subside over time. My doctor and I have found the perfect dosing and schedule for me to keep my blood sugar under control."

• SuT...
• Taken for less than 1 month
• August 4, 2021

Semaglutide for Type 2 Diabetes "I have been on Rybelsus for 11 days now. The first few days were horrible. I had diarrhea and stomach pains, even threw up twice. I am still having side effects on day 11 but not as bad. I’m taking Zofran for the nausea. I have already lost 8 lbs, which I’m sure is not healthy, but I don’t have an appetite on this medication. Before this medication, I would eat all the time, it seemed like I never was full. My sugar levels are as low as they’ve ever been. I am tired and have lower energy. I'm hoping after another week on it the side effects will subside. I have been struggling with weight loss my whole adult life and can never break through the plateau phase. I think this medication will help if I can withstand the side effects."

• Suz...
• Taken for less than 1 month
• July 22, 2021

Semaglutide for Type 2 Diabetes "I’ve taken two doses of Ozempic .25 mg and been on the drug for 1 1/2 weeks. I won’t be able to continue. This is a very harsh drug, and the side effects are terrible, in my opinion. I did not suffer from nausea and vomiting but couldn’t eat, food tasted horrible, my body stopped absorbing fat (evidenced in my stools), had lightheadedness, and the worst fatigue imaginable. In 1 1/2 weeks, I’ve dropped 10 pounds and feel undernourished and dehydrated. Be careful!"

• Jen...
• Taken for less than 1 month
• August 19, 2021

Semaglutide for Type 2 Diabetes "I was prescribed Ozempic for Type 2 diabetes to help lower my blood sugar and to help with weight loss. The first week wasn't so bad, just a little fatigued and some upset stomach problems. The second week it kicked in overtime and hit me like a brick wall. I had no energy at all. Stayed in bed because it's all I could do. My stomach was so upset and nausea, vomiting, and diarrhea were so bad, it ran like water. I became more dehydrated with less energy. I have 4 autoimmune diseases and this was the sickest I have ever felt in my life. I almost went to the ER and if not for Covid, I would have. It felt like someone had been feeding me rat poison. It's the worst feeling ever. I truly don't know how this drug was approved by the FDA. I plan to take myself off it. Weight loss and blood sugar need to be done in a healthier manner. Lose weight fast and easy has consequences."

• Zam...
• Taken for 1 to 6 months
• September 6, 2024

For Weight Loss (Obesity/Overweight) "I've been on semaglutide for nearly 4 months. I struggled with fatigue, nausea, and constipation the first few weeks. I almost gave up, felt like I'm wasting my time and money. Honestly, the change felt like it happened overnight, I looked in the mirror and saw a different me. I feel lighter, and my tummy feels soft. I struggle with back pain, but it's calmed down already. I feel happier and more active. I'm far from my goal, but definitely sticking to this. My appetite has reduced a lot. It won't work overnight, but it sure does work. Giving myself 8 more months, I'm confident I'll have my body back. Eating healthy and keeping up helps. Love this, it works for me, and it can work for everyone."

• Bre...
• Taken for 1 to 6 months
• June 14, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I began using Wegovy injectable semaglutide exactly 8 weeks ago today and have had very few symptoms, until the 7 1/2 week mark. At first, my nose ran continually, but that was somewhat manageable with Robitussin (recommended by the pharmacist) for the cough it caused. At dinnertime, at the 7 1/2 week mark, fatigue hit very hard. We were on a trip, and I could barely walk to get back to the hotel and fall in bed. This continued for 48 hours with no desire for food or drink, except ice water. I slept for 5 or 6 hours and awoke with a headache, which lasted the rest of the night. Strange because I do not get headaches. Thankfully, we were headed home at that point, and I slept in the car most of the day for two days. I am much improved and can function somewhat, but not back to normal yet. I am due to double my dose today, but the medication not available for a while due to high demand. Easy to use and have lost 10 lbs in 8 weeks."

• Jea...
• Taken for less than 1 month
• June 7, 2023

Semaglutide for Type 2 Diabetes "Nausea, bad acid reflux at night, nightmares, headache every morning, constipation, chills, fatigue. Just started a week ago. Blood sugar levels in the 80s and 90s. Have lost no weight. Zero appetite. Blurry vision."

• lee...
• Taken for less than 1 month
• June 15, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "This is my second week on Wegovy. During the first week, I felt fine, but this week, I am experiencing extreme fatigue, tachycardia, headache, and craving sweets. I find myself not eating anything other than meat and no sides. I think I might be done with it. I don't like feeling like this. It's just the second week, and I can't imagine what the third week would feel like."

• Apr...
• Taken for 1 to 6 months
• August 25, 2021

Semaglutide for Type 2 Diabetes "I have been on Ozempic for 20 weeks now, and I still experience bloating, flatulence, nausea, and fatigue. My A1C went back to normal, but I feel sick all the time. My most horrible side effect is the rotten egg smell of my burps. I am also taking Toujeo and Janumet."

• Anonymous
• Taken for 1 to 6 months
• June 30, 2024

Semaglutide for Type 2 Diabetes "After 4-6 weeks, I still suffer various levels of intensities of nausea, but short-lived diarrhea, plenty of burping, and fatigue that is often overwhelming. Some days, no problems. I manage the symptoms by enduring until they ease up, or I may choose to seek fast relief using what's available. Its benefits are now close to 'tight control' and significant weight loss (overcoming the stagnant plateau of a period of weight loss)."

• vtn...
• Taken for 1 to 6 months
• May 29, 2024

Semaglutide for Type 2 Diabetes "One month on Rybelsus. Blood sugar levels are down from 150 to 116-96. I have extreme nausea, constipation, and I am unable to eat more than 1-2 cups of food at a meal. I am rarely hungry. Food seems to become lodged in my esophagus and is painful. I have lost 13 lbs. in a month. Fatigue is an issue. My autoimmune retinopathy, which surfaced after cataract surgery, is worse. I fear I will not be able to continue this med."

• Pat...
• Taken for 1 to 6 months
• August 29, 2022

Semaglutide for Type 2 Diabetes "I have been taking this drug for about 8 weeks, starting out with the 0.25 dose and now on the 0.5 dose. I have felt miserable the whole time, with nausea similar to pregnancy and with a revulsion to most food and smells of food cooking. Definitely low energy. I have lost weight, and I haven’t had my A1C checked since I started. I will see my doctor in a couple of weeks and will be telling her that I can’t continue to live this way. I’m 75 years young and don’t want to live the rest of my years feeling bad! Unusual, hiccup-type burps, coming out of nowhere and no appetite. Convenient once-a-week administration."

• Suz...
• Taken for 1 to 6 months
• June 20, 2022

Semaglutide for Cardiovascular Risk Reduction "I started Ozempic in January 2022. Began with the standard .25 for 4 weeks, then .50 for an additional 4. When I injected the 1 mg, I was sick constantly. Vomiting, fatigue, and horrible heartburn. I had to stop for several weeks as I was completely worn out. I started again with the .25 and am now on the .50, but I'm noticing I am much more hungry than I was the first time around. I was wondering if any of you have injected .75 and if you found it to be helpful? I am afraid to try the 1 mg again as sick as it made me."

• Pri...
• Taken for less than 1 month
• May 20, 2022

Semaglutide for Type 2 Diabetes "My doctor put me on this because I was pre-diabetic, and he said I was insulin resistant. Since I’ve been taking it, I’m not as hungry, but my head hurts, and I always feel dehydrated, and so I’m peeing all day. I feel short of breath, and my chest has been feeling pains. I’m also experiencing constipation and constant light-headedness, and I’ve only been on it for 2 weeks. I may give it another 2 weeks, but not sure if the side effects are worth all this. I feel no energy, and my legs are always sore, and I’m so tired all the time. My way of living has suffered because I’m too tired to do anything and feel yuck all the time. Trying not to be frustrated because if this doesn’t help me, he wants to put me on Jardiance, but I hear so many horror stories about that one. This one isn’t as great as everyone said it would be, so who knows, maybe Jardiance will be better for me."

• Mem...
• Taken for less than 1 month
• September 3, 2021

Semaglutide for Type 2 Diabetes "I have Type 2 diabetes that I’ve kept under control by taking Metformin, Jardiance, and insulin. I saw a new endocrinologist 2 weeks ago who suggested I try Ozempic, with the hope of eliminating the insulin. She prescribed taking .25 mg initially for 4 weeks and then bumping up to .50, also reducing my insulin to 15 units and hopefully eliminating it later. She did say it could cause some stomach issues, but mainly said it could make you not want to eat much. I think in hindsight she downplayed the side effects. I took my first dose a week ago. The first 3 days were fine. The 4th day I started having foul-tasting belches and then got such severe stomach/gas cramping I almost went to the ER. I have a high pain tolerance, so for me to be in that much pain says a lot. I was able to finally get relief by drinking baking soda water, but then had extreme diarrhea, nausea, body aches, and fatigue. I missed 2 days of work. I called the doctor, and she said my symptoms were severe and to stop taking it. Horrible experience!"

• Bra...
• Taken for 1 to 6 months
• July 31, 2021

Semaglutide for Type 2 Diabetes "I have been taking Ozempic for about 4 months now. Haven’t had really bad side effects, but sometimes I feel just exhausted and somewhat out of breath. I also have muscle aches and fatigue. Not lost a lot of weight, maybe 2 lbs. I keep hoping. Does anyone else have similar side effects? Good luck and all the best results for everyone."

• Mac...
• Taken for 1 to 6 months
• June 13, 2023

For Weight Loss (Obesity/Overweight) "I experienced frequent headaches, fatigue, constipation, anxiety, mild depression, lack of interest in activities, aversion to alcohol, and dry mouth. I did have a 14-pound weight loss over 3 months. It is a slow and steady loss, which is reasonable."

• BJB...
• Taken for 1 to 6 months
• May 20, 2023

For Weight Loss (Obesity/Overweight) "I started using semaglutide for weight loss at the lowest dose, and each 4 weeks raised the dosage. I did not lose a single pound in all that time. I am a yoga instructor and practice 4 times per week. I became so severely constipated that I ended up in the ER. I battled with very severe fatigue, weakness, at times overly hungry, blurry vision, and a feeling of just being 'out of it.' I feel like I lost 3 months of my life. After taking my last dose 9 days ago, I’m still having bouts of diarrhea, stomach pain, and headaches. It was not worth it at all for me."

• Tko...
• Taken for 1 to 6 months
• May 23, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I started approx. 3/29 and will begin my third step up to 1 mg this week. I have lost 23 lbs in 8 weeks. Very happy about that. My appetite is reduced. I can sometimes skip dinner because, after a light lunch and breakfast, I am not hungry. I have experienced fatigue, nausea, and constipation. However, if I eat something like an apple with peanut butter, that helps with the constipation. So far, these side effects are not bad enough for me to discontinue. I would like to feel better, but I am hoping it will improve. Fatigue is the worst for me because I also have another autoimmune disease that causes extreme tiredness. I am taking a multivitamin and see my doctor in a week, and I will discuss negative side effects. Right now, the benefits of losing weight are worth it."

• Jan...
• Taken for 1 to 6 months
• March 22, 2023

For Weight Loss (Obesity/Overweight) "I started on January 24 on the 0.25 mg dose for 5 weeks, currently on 1 mg, and have lost a total of 20 lbs exactly as of this morning. It did cause some fatigue, stomach pain, and severe constipation (however, I have dealt with this all my adult life). I am loving how I feel regardless of the side effects. I find intermittent fasting has been so easy compared to prior attempts. I am not exercising more than walking. I am losing weight that I have never been able to lose, and I look forward to continuing until I reach my goal weight and maintain it."