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Semaglutide and Burping: What Users Say (Page 2)

Brand names: Ozempic, Rybelsus, Wegovy

Reviews for Semaglutide

Commonly mentioned side effects
  • GAF...
  • Taken for 1 to 6 months
  • January 28, 2025

For Weight Loss (Obesity/Overweight) "Wegovy was prescribed for weight loss, with a secondary potential benefit being a reduction in glucose levels and A1C. Began at minimal dose of 0.25 mg/0.5 ml. Had virtually no side effects. Also lost exactly 0 lbs. However, this first month included Thanksgiving, so a bonus that no weight was gained. Second month dose increased to 0.5 mg/0.5 ml. Side effects were primarily indigestion, some headaches, and very occasionally low blood pressure, but it included Christmas, so a positive was no gain. Month 3 increased dose to 1.0 mg/0.5 ml. In the first week at this dosage, can finally feel the appetite suppression. Side effects have included indigestion, burping, headache, and a bit of feeling sluggish. It has been very easy to administer the injections. I have been using the lower part of my stomach as the injection site, alternating from left to right side each week. So far, each injection has succeeded."

7 / 10
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  • Jer...
  • Taken for 1 to 6 months
  • June 20, 2023

For Type 2 Diabetes "It was a disaster for me. My A1C used to stay between 7.5 and 8.5, and morning fasting readings were high, like 130 to 160. Increasing Glimepiride from 4 mg up to 8 mg didn't work. My doctor started me on 3 mg/day of Rybelsus. It caused constipation, upset stomach, and a lot of burping. But morning fasting readings came down to around 100, so I was tempted to try it out. After finishing the 3 mg dose for 30 days, I started taking 7 mg/day. My symptoms worsened: constipation, loss of appetite, noisy stomach, lots of burping, GERD, and weight loss from 152 lbs to 139 lbs in just about a couple of months. I could not afford to lose any more weight. I also saw some foamy urine indicating it was affecting my kidney function too. I stopped taking Rybelsus under my doctor's advice, and since then, the constipation is gone, the burping is gone, the appetite is good, and life seems back to normal. I still need to check on my kidneys for any issues since foamy urine is still there. The last A1C was 7.9."

1 / 10
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  • Bak...
  • Taken for 1 to 6 months
  • May 24, 2019

For Type 2 Diabetes "I have been on Ozempic for 3 months now, and I find this drug works like none I have tried before. The first 6 weeks were rough: burping, headaches, fatigue, nausea, but I stuck it out. I’m so glad I did. My A1C has gone from 8 to 6.8 in three months. I have lost 20 pounds, going from 180 to 160 lbs. My daily sugars have seen a vast improvement. The major thing I have noticed after being on the drug for this long is that recovery time after eating high-carb or high-sugar foods is back to normal. Appetite is still lacking, but it’s mostly an aversion to ‘bad’ food. I can no longer sit and eat an entire burger, it’s just way too much, but a healthy salad, I can eat the whole thing! I have seen major benefits from this drug. I have way more energy and no more 3 pm crash. Tips while adjusting to the drugs: Tums, Gravol, lots of sleep, light healthy meals, and remember to drink water! Also, I found injecting Ozempic in the hip lessened the symptoms for the first while."

10 / 10
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Frequently asked questions

  • Dan...
  • Taken for 1 to 6 months
  • April 5, 2023

For Weight Loss (Obesity/Overweight) "I wanted to warn people of the side effects, as my doctor did not prepare me for this med. I am very glad I didn't try to work, otherwise, I would have lost my job or, at the very least, been written up for various reasons. On it for a month. I tried spacing out the second shot and never ended up taking the last injection. Side effects: severe fatigue, severe hair loss, decreased hormones, severe headaches, changes in your sleep architecture, bad nightmares for all sleep, naps, and overnight. Warning: if you have PTSD, that may mess with you. Bladder urgency and UTI symptoms started on day 3 and were constant the whole time on the med, I had to take AZO. Bloating, burping, throwing up, and all food smells make you sick, severe constipation, hypoglycemia, and increased binge eating. I also had increased topical psoriasis and arthritis pain. Started having problems with my foot and wondering if it's impacting ligaments. I am getting that checked out. Did not reduce the need to eat, no weight loss."

1 / 10
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  • Mar...
  • Taken for 1 to 6 months
  • July 14, 2021

For Type 2 Diabetes "Started taking Ozempic back in February after I asked my doctor to put me on it because of reading a British study on weight loss by semaglutide. Started at the 0.25 mg level for three weeks. Went to 0.50 for another four weeks and have been on 1 mg thereafter. No serious side effects apart from some belching, acid reflux after bedtime, and rare diarrhea. Significant loss of appetite, change of taste in foods, change of perceived texture of foods, significant reduction in alcohol enjoyment and intake, and increased sensitivity to cold. My A1C has gone from 6.7 to 6.0, and I have lost over 35 pounds since the start. My cholesterol is down to 115 and LDL down to 50, something I have never seen before. Overall, the results far outweigh the downsides of this drug and it has provided the most positive results faster than any other medication I have tried before."

10 / 10
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  • Bec...
  • Taken for 1 to 6 months
  • April 21, 2025

For Weight Loss (Obesity/Overweight) "I started at 0.25 ml mid-January 2025. After one month and no side effects, I was down 16 pounds. Second month I titrated up to 0.5 ml. No side effects and lost an additional 8 pounds. Third month titrated up to 1 ml. Three days in, I have been experiencing explosive, uncontrollable diarrhea, sulfur burps, and mild stomach cramps. Trying to control it with Pepto-Bismol and Imodium offered only a brief half-day respite, and then the diarrhea was back with a vengeance. Still losing about 2 pounds per week, but only sticking to the BRAT diet, supplementing with saltines and oatmeal. Water and Gatorade are my main sources of fluids as I am trying to stay hydrated. Decided to speak with the doctor and seek blood work and stool sampling just to make sure nothing else is going on. Depending on what comes of this, I hope to keep continuing on with this medication as it has helped me tremendously with weight loss, lowered my A1C, and boosted my self-confidence with respect to how I look and feel."

9 / 10
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  • Sal...
  • Taken for 1 to 6 months
  • February 7, 2021

For Type 2 Diabetes "Started with .25 for 4 weeks, then .5 after that. I don't have much of an appetite, which is good because I do need to lose weight. I cannot finish a portion of food I usually eat. I have pain, burping, and constipation daily. I am okay in the morning when I wake up and after breakfast (eggs, oatmeal, or yogurt). I usually eat lunch-supper at 2-3 pm. The real pain and burning start 3-4 hours later and last till I go to bed. If I drink water, it gets worse. When I lie in bed, the pain goes away. I have not had problems with indigestion, so I wonder if this is causing it? I worry about kidney and pancreatitis. I will see my MD this coming week and discuss all this with him. I lost 10 lbs, and my A1C went from 10.3 to 9.1. Wonder how long it takes for the A1C to get below 7?"

2 / 10
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More FAQ

  • Wor...
  • Taken for 1 to 2 years
  • July 4, 2019

For Type 2 Diabetes "When I started Ozempic at a dose of 0.25, I lost 10 pounds, sugar levels dropped from 6.7 to 6.3. I experienced a hard time wanting to drink water and felt water-logged after I drank water. The doctor increased the dose to 0.5, and 4 months ago I started having diarrhea, sulfur burps, bloating, fatigue, and more seriously, a lump on the right side of my throat and a sore throat. My doctor was surprised that I had these side effects a year later after taking the medicine. Ozempic is the only medication I'm taking other than vitamin D, B12, and calcium. My ultrasound shows several lumps, some larger than others, and now I'm waiting for the referral to see a nose, ear, and throat specialist. I stopped taking Ozempic 3 weeks ago. Worried about the side effects of thyroid cancers..."

1 / 10
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  • Ano...
  • Taken for 6 months to 1 year
  • April 20, 2025

For Weight Loss (Obesity/Overweight) "I started Wegovy in October at the lowest possible dosage and worked up to 1.7 by February. I had no side effects and very slowly lost weight, which I was fine with. I lost 35 pounds in six months. However, oddly enough, after five weeks at 1.7 with no side effects, I became quite ill. I started having the sulfur belches, followed by vomiting and severe diarrhea. I went to urgent care. They said it was a normal response and to take anti-diarrhea meds. I did. It got worse, to the point of diarrhea every 15-20 minutes. After six days of this, I went to the emergency room. They admitted me. I spent nine days in the hospital with severe dehydration, which caused my kidneys and pancreas to start shutting down. Docs felt I had a separate bacterial bug not caused by my shots. I was finally able to go home. My doctor had me start back at a safer .25 dose. I did, but immediately got sick again. I think I need to stop these meds, sadly, as they did originally help me, but I can’t go on this way."

6 / 10
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  • Tuu...
  • Taken for 6 months to 1 year
  • July 23, 2021

For Type 2 Diabetes "I started with 0.25 Ozempic in November 2020 and upped my dosage to 0.5 in January 2021. My A1C is the same as when I was taking 2000 mg Metformin daily (5.1-5.3%). My doctor decided to switch me to help with weight loss and manage my pre-diabetes. I have lost 47 lbs, which is great, but it isn't a healthy way to lose weight. I met with a GI specialist and was diagnosed with gastroparesis, they had me discontinue Ozempic to see if my symptoms would disappear. That was 6 weeks ago, and my stomach is still paralyzed. I have sulfur burps, diarrhea, severe constipation, and vomiting daily. I now have to eat a low FODMAP diet and can only manage a few mouthfuls of food at a time. I have no quality of life anymore, I can no longer enjoy many of the things I used to, which has caused me severe anxiety and depression. While the weight loss benefits sound appealing, please think twice before taking this drug."

1 / 10
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  • Cal...
  • Taken for less than 1 month
  • May 12, 2023

For Weight Loss (Obesity/Overweight) "My experience with Wegovy has been a rollercoaster. In the first week, the 0.25 mg dose was great. In the second week, I started feeling the side effects of nausea, burping, gas, diarrhea, and bloating. I noticed that I did eat more. Make sure your portions are small and stick to fruit and vegetables. Soups and not greasy processed foods. You may feel sick and will take longer to digest. I am currently reconsidering if I should continue. I am not sure if I want to experience the side effects at a higher dose. I feel terrible all the time and have a headache. I feel exhausted all the time."

5 / 10
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  • Dut...
  • Taken for 1 to 6 months
  • September 6, 2024

For Weight Loss (Obesity/Overweight) "I'm almost 2 meters long, and when I started, I was more than 157 kg. Within 11 weeks, I lost 22 kg. Almost every week, I lost 1.5 kg and more after the big water loss. For me, it's an addition to the bigger plan. Yes, I use Wegovy (now on 1 mg), but I also go to the gym 5 times a week and add some hour-long walks to my day. And yes, I also have a strict timeframe where I have my meals. And yes, they are mostly veggies and some yogurt with some granola for some fiber. I had some side effects like heartburn, burping, constipation, and I'm more tired than before. But I think that's a normal thing to process, especially when you make the transition. If you are seriously overweight, please consider this medicine as a small part of the bigger plan!"

10 / 10
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  • mew...
  • Taken for 1 to 6 months
  • August 27, 2024

For Type 2 Diabetes "I’m 63 F with T2 diabetes, and I started on Oz mid-May 2024. Symptoms: nausea, fatigue, GERD, sulfur burps, stomach cramping from severe constipation, constipation, feeling like I need to vomit, ringing in my ears has increased significantly, loss of appetite, reduction of inflammation, occasional migraines, feeling “off” most days, bouts of dizziness, and feeling faint, but blood sugar and blood pressure are normal, improved blood sugar readings, weight loss of 13 lbs. There are some perks: rheumatoid and osteoarthritis inflammation has lessened, though I still feel pain daily, it’s more tolerable. I take no painkillers but will take CBD as needed. Loss of appetite has led to a loss of 13 lbs so far, blood sugar improved so I’m confident that my A1C has improved also. I struggle with what to do: stay on for the inflammatory reductions, weight loss, and blood sugar improvement benefits, or quit because I feel sick most days, so I have no real pleasure in life anymore. No, I’m not depressed."

6 / 10
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  • JDM...
  • Taken for less than 1 month
  • October 4, 2018

For Type 2 Diabetes "I started on the low dose .25, had nausea, loss of appetite, little loose stool, tired, and just didn't feel good. Lasted for 3-4 days. Next dose, the symptoms increased, especially the loose stool, lasted most of the day for 4 days. The next dose, the doctor had me go to .5, and I say OMG, it was the worst I have ever felt. Couldn't eat, watery diarrhea, burping horribly, tired, and just felt so sick. I told my doctor I can't do this. Symptoms still going after being off for a week and a half. I just hope it stops soon. I do not recommend it to anyone."

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • July 7, 2019

For Type 2 Diabetes "Loved the weight loss, everything else sucked! Nausea, diarrhea, heartburn, sulfur burps, no appetite. I ended up with a nasty gallbladder that was poisoning my body. I turned septic and ended up hospitalized. The doctors, nurses, and hospital were wonderful, but my ordeal was not over. Ten days later, I had seizures and two small strokes. Had no calcium or magnesium left in my body. The most horrible experience ever! Yes, this medicine may be great. Please be vigilant about getting your blood work done on a monthly basis, especially if you are losing fluids through digestive upset. Like I said, the drug worked as far as weight loss (47 lbs) and A1C (6.6). But I came close to losing my life and am still recovering and working with my doctors to get back to a healthy life."

3 / 10
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  • Dan...
  • Taken for 1 to 6 months
  • July 4, 2019

For Type 2 Diabetes "Two days after the injection, I get a pretty bad headache, indigestion, and a bloated feeling that lasts the day. This week (6th shot) has been different. It’s the second week the dose was raised from .25 mg to .5 mg. I felt like I had to throw up. The indigestion, burping, constipation, sore muscles, aches, and heavy sweating all felt like I had a horrible flu. I stayed home from work. I went back to work today, when I normally get the headache, and had heavy sweating, burping, indigestion, cold clammy skin, bloating, diarrhea, and depression and anxiety (years since I had either one). Tonight I still have bloating, wrists and shoulders sore, and indigestion with burps. My neck is really stiff. The normal headache has started with a little dizziness. I am still debating what to do as this has been an effective medicine. My blood sugar has gone from 290 to 90 to 140 when I check it. I have lost weight as well."

7 / 10
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  • Joh...
  • Taken for 6 months to 1 year
  • October 19, 2024

For Weight Loss (Obesity/Overweight) "I can only thank the makers of these drugs. For 30 years, I have suffered from what is now known as food noise. Now, I feel normal. I can say no to foods that before I craved all the time. I still get cravings, but it's amazing that I can have a protein shake or something small and that feeling goes away quickly. Now, Wegovy wasn't easy at the start. I had bad symptoms at the start… very bad. I was often sick or had sulfur burps. It wasn't until I spoke with a well-educated nutritionist who supports these drugs that explained I needed to drop my dose below the 0.25. As soon as I switched to 0.10, then 0.20, then 0.40, this slower transition helped a lot. He also explained I should try a liquid diet… which I didn't like the sound of at first, but he explained if I had a small protein shake before meals or when I was hungry, it would be easily digestible and force me to eat very small solid food meals. My god, it helped. Now, after 9 months, I've lost 20% of my weight. Couldn't be happier."

10 / 10
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  • Sic...
  • September 7, 2019

For Type 2 Diabetes "Started Ozempic .25 dose 2 weeks ago. First week, ended up in the ER with dehydration from vomiting so much. Physicians didn't think it was this medication that was causing it. Endocrinologist was not available as it was Labor Day when this occurred. I didn't think anything of it, so I continued with another dose two days ago. This was a very stupid idea. I am severely nauseous with no vomiting this time, but it is miserable. Also a lot of sulfur burps. This lasted half the day today and is subsiding. But this is like a roller coaster and unsure when these symptoms will return. I am also experiencing fatigue nonstop. Hard to even move or concentrate energy. I thought this might be due to having normal blood sugar levels since taking this medication, but I don't think this is the case. Please be careful on this medication."

2 / 10
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  • Gra...
  • Taken for 1 to 6 months
  • January 1, 2022

For Type 2 Diabetes "If you have any form of stomach or bowel disorder or a history of pancreatitis, you may want to steer clear of Ozempic or any of the other similar drugs in its class. They slow gastric emptying, which can really get your system out of order and wreak havoc. If you start having sulfur burps, extreme nausea, horrific vomiting, and diarrhea, you’ll know it isn’t for you. For me, it got so bad, I was having to resort to wearing adult diapers. I initially thought I was having episodes of food poisoning or giardiasis, but it turned out to be medicine-induced gastroparesis and pancreatitis. Ozempic and the drugs like it may work great in some people, but be downright dangerous in others. Use with caution and pay attention to the warning signs. I just hope this will help someone else not have to go through what I did."

1 / 10
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  • LFI...
  • Taken for 1 to 6 months
  • April 26, 2023

For Weight Loss (Obesity/Overweight) "What I’ve always dreamt of. This is a miracle drug. Lost 6 or 7 kgs in 8 weeks, finally feeling the way I’ve always wanted to feel. Comfortable in my body and not a gluttonous pig. Slight nausea and burping, but so worth it."

10 / 10
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  • Tur...
  • Taken for 1 to 6 months
  • July 10, 2019

For Type 2 Diabetes "I have been on Ozempic for 2 months, and it has done wonders for me. I had been on insulin for 1.5 months prior to starting it and gained 20 lbs. I started on Ozempic, and my A1C dropped along with my daily numbers. I just stopped all insulin! I read reviews prior to starting on it and work really hard at not overeating and eating low carbs. I get bouts of nausea and burps at times, so I carry sugar-free mints with me. Nothing major. I’ve dropped 10 lbs and am on a 0.5 dose. This drug has been amazing for me. Watch portions, carbs, and greasy foods! So happy to be off insulin!"

9 / 10
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  • Nei...
  • April 16, 2021

For Type 2 Diabetes "Month 1, I was started on Ozempic at 0.25 mg and had very mild symptoms of bloating and reduced appetite. Month 2 & 3, uncomfortable. Stomach cramps, gas, and diarrhea probably for 4 days after injection. This can be really embarrassing in a small office. By the end of Month 3, I was feeling quite a bit better. At this point, my HbA1c was down to 5.2 from 9.4, I had virtually no diabetic symptoms. No blurred vision, no numbness in fingers and toes, and I was sleeping through the night without visits to the bathroom. And I lost 16 kilo in weight. Month 4 to 7. OMG. Increasing to 1 mg, the side effects are horrendous. Weight loss has stalled, though this is probably due to lockdown. The sickness and eggy burps are constant, and now my doctor says it will be at least 6 months before the side effects could be gone. But I have no diabetic symptoms, my HbA1c is pretty much normal, and I think the effort has been worth it. Not an easy journey, but worthwhile."

7 / 10
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  • Mar...
  • Taken for 1 to 6 months
  • November 28, 2021

For Type 2 Diabetes "I was on Metformin and had an A1c of 8. The doctor told me to get off Metformin and gave me a sample of 3 mg Rybelsus and prescribed the 7 mg dose after 1 month. My morning blood sugars with Metformin were 111 to 88. With Rybelsus, my blood sugar in the morning has been 148 to 208! I had diarrhea with Metformin, but that went away with Rybelsus, however, my stomach has become bloated, lots of burping, slightly nauseous, no appetite, a tightness in my chest, and now that I am using the 7 mg dose, I have become exceedingly tired with zero appetite. Today my blood sugar was 177. This is unacceptable. It was way lower with Metformin. I am quitting this. I can't be this tired and feeling so ill. I used to have energy with Metformin, but Rybelsus has completely drained it. I feel the doctor had just been visited by the Big Pharma salesman and gave her the sales pitch, and she started prescribing it. Is she getting a kickback? This Rybelsus is not good and causes cancer."

1 / 10
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  • Hat...
  • Taken for less than 1 month
  • July 19, 2022

For Cardiovascular Risk Reduction "This is the worst medication I have ever had. Side effects of egg burps, vomiting, bloating so bad. DO NOT TAKE THIS. 30% of people that try this drug end up having problems with it. DO NOT TAKE. You can't eat, everything that goes into you makes you want to throw up. DON'T TAKE! Never-ending nausea and weakness. DON'T USE, SAVE YOURSELF. Headaches....."

1 / 10
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  • Sal...
  • Taken for less than 1 month
  • July 8, 2018

For Type 2 Diabetes "I started Ozempic exactly one week ago. The nausea hit by the second day but only seemed to happen in the morning. However, 5 days in, the diarrhea hit. It has been absolutely horrendous. The gurgling sounds can be heard from across a huge room. I have woken up to bowel leakage and been running to the bathroom about 10 times a day for the last 3 days. Then there’s belching, which is worse than a typical 'burp.' It’s happening regularly too. I’m really sad and afraid. I really thought this was going to help me bring down my A1c. But I don’t see how I can continue taking it. I’m calling my endo tomorrow. I need something to work, but these side effects are just not livable. Especially because I work in a corporate atmosphere."

4 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.