Ozempic and Vomiting: What Users Say

• Oze...
• Taken for less than 1 month
• May 14, 2023

For Weight Loss (Obesity/Overweight) "With just one 0.25 mg dose, I became very ill. Relentless nausea, vomiting, and explosive diarrhea, as well as unbearable stomach cramps. Needed to go to the ER for fluids and to check for pancreatitis. It’s now been 9 days since my first dose, and I still have relentless diarrhea, nausea, and disabling fatigue. I don’t want to eat. I didn’t want to take it in the first place but was ambushed by my kidney doctor. She told me that using Ozempic was a no-brainer and that I would just have a bit of nausea. If you have any gastrointestinal symptoms when taking any medicine, I would think three times about it before using it. I have read it can take up to a month for it to be flushed out of your body, but I am hoping and praying that these horrible side effects stop real soon."

• DAn...
• May 12, 2021

For Cardiovascular Risk Reduction "Within 12 hours of the first dose, vomiting occurred and continued for 3 days. Unable to keep any food down; small sips of ginger ale the only thing I did not vomit. Lower abdominal tight cramping. Pain in the upper abdomen. Vomiting at all times of day and night, which added to the fatigued feeling. Days 4-7 felt queasy. Second injection: same side effects as first. Emetrol helped me eat dry toast (1/2 slice) and weak tea. Third dose: same effects, but only for 2-1/2 days."

• Sic...
• September 7, 2019

For Type 2 Diabetes "Started Ozempic .25 dose 2 weeks ago. First week, ended up in the ER with dehydration from vomiting so much. Physicians didn't think it was this medication that was causing it. Endocrinologist was not available as it was Labor Day when this occurred. I didn't think anything of it, so I continued with another dose two days ago. This was a very stupid idea. I am severely nauseous with no vomiting this time, but it is miserable. Also a lot of sulfur burps. This lasted half the day today and is subsiding. But this is like a roller coaster and unsure when these symptoms will return. I am also experiencing fatigue nonstop. Hard to even move or concentrate energy. I thought this might be due to having normal blood sugar levels since taking this medication, but I don't think this is the case. Please be careful on this medication."

• nau...
• December 30, 2020

For Type 2 Diabetes "I started Ozempic .25 mg subcut 8 days ago. I took my second dose yesterday. My first week, I ended up in the ED. I thought I had a bowel blockage or ileus. The ED visit was preceded by 6 hours of constant, sickening, odiferous belching, constant flatus, eruptive vomiting, cramping, and pain. A CT scan revealed gastric paresis. The event was precipitated by a fatty meal. I have since learned that the decreased gastric motility demands drastic changes in the volume of food intake, fat content, and most importantly, patience with what I consider to be major side effects. Now, I have no appetite. I am nauseated all the time, taking Zofran 4 mg before any meal. The belching is greatly reduced, same with flatus. I feel constipated, but that is easing off. I am avoiding high-fat foods and eating smaller portions. I am profoundly fatigued. Tomorrow, I am getting on the treadmill for 30 minutes each day to stimulate endorphin release to feel better. I have read the symptoms are reduced after 4-6 weeks."

• Jca...
• Taken for less than 1 month
• June 25, 2019

For Type 2 Diabetes "Horrible, debilitating fatigue, needing naps that I’ve never needed daily! Painful intestinal pressure and gas that wakens me from sleep, that cannot be burped or passed out. No noticeable difference in my blood sugar levels (my A1C was already 5.6). A little vomiting. If this fatigue does not subside, I believe I will stop using and seek other alternatives. I hate this, I want my life back."

• Nes...
• Taken for 1 to 6 months
• May 3, 2019

For Type 2 Diabetes "Was diagnosed with type 2 diabetes in March 2019. Doctor put me on Ozempic rather than insulin, although it's not recommended. He thought it was worth a try along with 500 mg metformin twice daily. The first 3 weeks of 0.25 mg Ozempic were just fine. Very minimal side effects - occasional diarrhea, some gas, and belching. Nothing I couldn't handle. The fourth week of 0.25 mg was worse. Constant diarrhea for four days, nausea, some vomiting. I went to a different doctor thinking I had a stomach virus, he prescribed me an anti-diarrheal, and I felt better. I took the Ozempic at 0.5 mg then, as prescribed. Two days later, nightmare. Diarrhea again, vomiting, nausea, and serious fatigue. I'm in the throes of it right now, and I'm going to be contacting my doctor to see what I can do to counteract this. Besides the side effects, though, it's working beautifully. My blood sugar is down from the high 300s to the low 100s in just a month."

• Suz...
• Taken for less than 1 month
• July 22, 2021

For Type 2 Diabetes "I’ve taken two doses of Ozempic .25 mg and been on the drug for 1 1/2 weeks. I won’t be able to continue. This is a very harsh drug, and the side effects are terrible, in my opinion. I did not suffer from nausea and vomiting but couldn’t eat, food tasted horrible, my body stopped absorbing fat (evidenced in my stools), had lightheadedness, and the worst fatigue imaginable. In 1 1/2 weeks, I’ve dropped 10 pounds and feel undernourished and dehydrated. Be careful!"

• Jen...
• Taken for less than 1 month
• August 19, 2021

For Type 2 Diabetes "I was prescribed Ozempic for Type 2 diabetes to help lower my blood sugar and to help with weight loss. The first week wasn't so bad, just a little fatigued and some upset stomach problems. The second week it kicked in overtime and hit me like a brick wall. I had no energy at all. Stayed in bed because it's all I could do. My stomach was so upset and nausea, vomiting, and diarrhea were so bad, it ran like water. I became more dehydrated with less energy. I have 4 autoimmune diseases and this was the sickest I have ever felt in my life. I almost went to the ER and if not for Covid, I would have. It felt like someone had been feeding me rat poison. It's the worst feeling ever. I truly don't know how this drug was approved by the FDA. I plan to take myself off it. Weight loss and blood sugar need to be done in a healthier manner. Lose weight fast and easy has consequences."

• Suz...
• Taken for 1 to 6 months
• June 20, 2022

For Cardiovascular Risk Reduction "I started Ozempic in January 2022. Began with the standard .25 for 4 weeks, then .50 for an additional 4. When I injected the 1 mg, I was sick constantly. Vomiting, fatigue, and horrible heartburn. I had to stop for several weeks as I was completely worn out. I started again with the .25 and am now on the .50, but I'm noticing I am much more hungry than I was the first time around. I was wondering if any of you have injected .75 and if you found it to be helpful? I am afraid to try the 1 mg again as sick as it made me."

• Rob...
• Taken for 1 to 6 months
• March 1, 2025

"I have been taking Ozempic for five months, and I have lost 35 pounds. That’s the good part. I continue to have very bad fatigue, and when I upped my dose, I find myself nauseous and vomiting. I’m gonna continue taking it for a little while longer to reach my goal. So far, it has been worth it for me."

• joh...
• Taken for 1 to 6 months
• June 16, 2025

For Type 2 Diabetes "Reduced blood sugar from 10 to 7.1. Killed my hunger completely, no more food cravings. Side effects became disabling, had to discontinue using. Became bloated, nausea was bad, 1st time I have vomited in 50 years, fatigue, constipation, going to the emergency room as no doctors available to help."

• Kez...
• Taken for 1 to 6 months
• May 10, 2023

For Type 2 Diabetes "I’m in my second month of Ozempic. The first dose level (0.25 mg) wasn’t difficult. I felt good, with minimal nausea, mostly fatigued and gassy. Moved up to 0.5 mg 3 days ago, and oh boy, nausea ++ heartburn ++ have vomited twice. Holding out because I had been running with very high blood sugars due to poor diet and med compliance, peeing every 2 seconds, and drinking the well dry, but now I sleep all night, have to remind myself to drink, so those are the symptoms I prefer. I feel lighter and my clothes feel looser, haven’t weighed myself yet."