Ozempic and Upset Stomach: What Users Say

• Oze...
• Taken for less than 1 month
• May 14, 2023

For Weight Loss (Obesity/Overweight) "With just one 0.25 mg dose, I became very ill. Relentless nausea, vomiting, and explosive diarrhea, as well as unbearable stomach cramps. Needed to go to the ER for fluids and to check for pancreatitis. It’s now been 9 days since my first dose, and I still have relentless diarrhea, nausea, and disabling fatigue. I don’t want to eat. I didn’t want to take it in the first place but was ambushed by my kidney doctor. She told me that using Ozempic was a no-brainer and that I would just have a bit of nausea. If you have any gastrointestinal symptoms when taking any medicine, I would think three times about it before using it. I have read it can take up to a month for it to be flushed out of your body, but I am hoping and praying that these horrible side effects stop real soon."

• Haz...
• Taken for 1 to 6 months
• September 18, 2019

For Type 2 Diabetes "Blood sugar levels started getting high 33 a year ago, tried several different prescriptions before being placed on Ozempic (4 months ago), metformin & Invokana. Now reading 6.5 levels, with a recent 7.0 A1C. In the past 4 months have gone from 170 to 141 lbs. I was told weight loss included muscle loss so I’m trying to keep on a high-protein diet and weight workouts. I don’t think I’ve had a hunger pang in 4 months, and eat way less. I do get burps after eating and occasional stomach pain that is tolerable. Perhaps it’s the combination of all bringing down my levels that gives me two things I didn’t expect, clear clarity in thinking (better memory recall) and a lot more energy (as in stable for a good 10 hours and then I start getting fatigued). I honestly am very happy to lose weight and eat off a smaller plate."

• Dke...
• Taken for 1 to 6 months
• May 19, 2023

For Weight Loss (Obesity/Overweight) "I had high hopes for this drug and stuck with it as long as I could, but it caused severe constipation, stomach cramping, and fatigue. I started out with .25 mg for 4 weeks, then .50 for 2 weeks. I didn’t lose weight, so my doctor increased the dose to 1 mg, but I just couldn’t tolerate the side effects at the lower doses, so I didn’t even try the 1 mg."

• mew...
• Taken for 1 to 6 months
• August 27, 2024

For Type 2 Diabetes "I’m 63 F with T2 diabetes, and I started on Oz mid-May 2024. Symptoms: nausea, fatigue, GERD, sulfur burps, stomach cramping from severe constipation, constipation, feeling like I need to vomit, ringing in my ears has increased significantly, loss of appetite, reduction of inflammation, occasional migraines, feeling “off” most days, bouts of dizziness, and feeling faint, but blood sugar and blood pressure are normal, improved blood sugar readings, weight loss of 13 lbs. There are some perks: rheumatoid and osteoarthritis inflammation has lessened, though I still feel pain daily, it’s more tolerable. I take no painkillers but will take CBD as needed. Loss of appetite has led to a loss of 13 lbs so far, blood sugar improved so I’m confident that my A1C has improved also. I struggle with what to do: stay on for the inflammatory reductions, weight loss, and blood sugar improvement benefits, or quit because I feel sick most days, so I have no real pleasure in life anymore. No, I’m not depressed."

• Swi...
• Taken for 1 to 6 months
• May 13, 2019

For Type 2 Diabetes "Started on Ozempic 5 months ago for diabetes 2. Started at 0.25, then 0.50, now at 1.00, and so far I lost weight - 35 lbs. But I’m feeling really fatigued, dizzy, and occasional stomach ache, diarrhea, and my eyesight has changed. Great drug for lowering A1C and losing weight, but the side effects are horrible. I think I’m done taking this drug. Side effects are getting worse."

• Ren...
• Taken for 1 to 6 months
• July 22, 2022

For Type 2 Diabetes "I am a 68-year-old male with Type 2 diabetes. I tried Ozempic .025 low dose, to also lose weight. Have been on it for 5 weeks and have had an upset stomach and constipation since the beginning. Only lost 6 lbs. To me, the side effects of always feeling sick and not hungry, which for me led to tiredness and fatigue, even though I take vitamins, is definitely not worth it. Blood sugar went down below 100 for the first 3 weeks but has gone back to upper normal, 140-150 since then. Not worth it to feel sick all the time. I am quitting this stuff."

• Cat...
• Taken for 6 months to 1 year
• March 8, 2023

For Type 2 Diabetes "I've been on Ozempic 0.25 mg since last March. Had a lot of stomach problems for the first 3 months and stopped for a month to calm my stomach. Lost 16 pounds in the beginning, but that has come to a standstill. I have noticed, besides stomach issues, mood swings, mild depression I didn't have prior, fatigue, and still ongoing stomach issues. I will probably stop. While it notes there are cardiology benefits, for me, it's just not worth the side effects. My advice is to make sure you keep in touch with your doctor and tell them how you are feeling."

• Jen...
• Taken for less than 1 month
• August 19, 2021

For Type 2 Diabetes "I was prescribed Ozempic for Type 2 diabetes to help lower my blood sugar and to help with weight loss. The first week wasn't so bad, just a little fatigued and some upset stomach problems. The second week it kicked in overtime and hit me like a brick wall. I had no energy at all. Stayed in bed because it's all I could do. My stomach was so upset and nausea, vomiting, and diarrhea were so bad, it ran like water. I became more dehydrated with less energy. I have 4 autoimmune diseases and this was the sickest I have ever felt in my life. I almost went to the ER and if not for Covid, I would have. It felt like someone had been feeding me rat poison. It's the worst feeling ever. I truly don't know how this drug was approved by the FDA. I plan to take myself off it. Weight loss and blood sugar need to be done in a healthier manner. Lose weight fast and easy has consequences."

• Ris...
• Taken for 1 to 6 months
• May 15, 2025

For Weight Loss (Obesity/Overweight) "I have been on Ozempic for about 3 months. Started at 0.25, then went to 0.5, then went to 1.00 2 weeks ago. Had some minor side effects (a little stomach upset, fatigue) with the lower doses, but just this past week, I have started severe diarrhea. I literally can't keep anything in my system. It is working okay... I have lost almost 15 pounds, but I am going to adjust the dosage down if the diarrhea doesn't stop. I also have had a huge increase in burping, which is manageable. Overall, I have positive things to say about this medication, but I think that dosing is pretty specific to the person and should be discussed with your primary doctor if severe side effects continue."

• san...
• Taken for 1 to 6 months
• June 5, 2025

For Weight Loss (Obesity/Overweight) "Down 12 pounds in 4 weeks. Fatigue and stomach cramping are the side effects I am having most frequently."