Ozempic and Headaches: What Users Say (Page 2)

• jma...
• Taken for 1 to 6 months
• January 27, 2023

For Cardiovascular Risk Reduction "I started on the lowest dose of Ozempic in October 2022. One injection, in my thigh, once a week. I didn't make it past the first 4 weeks or the lowest dose. My physician hoped that since I do not have a gallbladder, many of the reported side effects of nausea and vomiting would not affect me. Wrong. First week and all things went well. I experienced no real side effects and had decreased appetite and energy. I slept well and was active. Second, third and fourth weeks, not so good. Modified my entire diet, but could barely eat or drink anything but a little chicken. Constant and severe nausea, vomiting, sleep deprivation, headaches, body aches, and zero energy for the next three weeks. It was like having a severe case of stomach flu for 4 weeks. Oh, I lost weight, between 18-20 lbs. Unfortunately, this is not a sustainable way of life. I couldn't function; I didn't leave my house for a month. I pulled myself off of it, and it took another 3 months to recover fully."

• Bet...
• Taken for less than 1 month
• July 5, 2019

For Type 2 Diabetes "Only second week in on the lowest dose. Feel lighter, no hunger at all. Suffering from nausea, wind, and headaches. I would really like to go the distance with this medication. I have overeaten for years and am wanting this to work. Not thinking of eating is quite liberating."

• mnd...
• Taken for less than 1 month
• March 14, 2019

For Type 2 Diabetes "Has anyone been irritable on Ozempic? I've been on it for 5 days. I've had the nausea, headache, and diarrhea, but I also feel very irritable (could be hormonal, LOL). Just curious if anyone else experienced that."

• Kom...
• Taken for less than 1 month
• November 27, 2019

"Oh boy. I just started Ozempic for weight loss at .25. After my first injection, I was fine for two days, and then was constipated for two days—and since then I’ve been pretty darn sick. Violent diarrhea, headaches, some nausea, and very low energy. I’ve taken several days off from work as I’ve felt so bad. I’ve lost weight since I have no appetite, and nausea follows whenever I eat—even broth and crackers. I have international travel planned in 10 days, and I hope that I’m recovered by then. I may try again after my travels, but this has been rough. The worst side effects I’ve had from a new medication."

• Ley...
• Taken for 1 to 6 months
• June 3, 2023

For Weight Loss (Obesity/Overweight) "From the initial starting dose until I went up to 1 mg, the whole 6 months was a roller coaster of nausea, headaches, and uncontrollable vomiting. The nausea was always followed by throwing up 5-7 times per day. If I ate or drank anything with too much sugar (including fresh orange juice), then I would throw it up within 30 mins. The sulfate mouth smell, along with the vomiting, was difficult and embarrassing. Exhausted and tired feeling, along with feeling depressed and hating/disgusted by food, is how I felt. I did lose about 8 kgs before moving on to Saxenda. Get ready for Ozempic to destroy your life for a few months if you want to lose weight with it."

• Ano...
• Taken for 2 to 5 years
• May 20, 2025

For Type 2 Diabetes "Nausea on a regular basis over two years of having it. Severe weight loss, even when not needed, as unable to face food. Blurred vision and pain in the eye. I don’t recommend it just for weight loss. I started on 0.25, going up to 0.5. Constant headache because of eye pain. I came off insulin, but am now stopping Ozempic, can’t put up with eye and headache. I would rather have insulin four times a day."

• C01...
• Taken for 1 to 6 months
• July 6, 2021

For Cardiovascular Risk Reduction "3 weeks in... Initially prescribed for weight management. While my appetite's drastically reduced, I've experienced headaches, some brain fog, and felt a little under the weather. Nausea slightly though it reduced day by day. Fatigue's unbearable. I typically have an upbeat, positive attitude and noticed a not-so-good version of myself just recently. Contemplating discontinuing treatment as excited as I am for the weight loss aspect of it :("

• Bra...
• March 15, 2021

For Type 2 Diabetes "Ozempic lowers my blood sugar. I have found in the 4 weeks I have been taking it, I have lost weight (not sure how much, but it's noticeable for the first time since I was diagnosed with type 2 diabetes 6 months ago). I am struggling to decide if it's worth being sick 2 days a week. I have extreme nausea (like I have mild food poisoning), a terrible headache, and I'm exhausted. The rest of the week, I feel fine. It is the two days following the injection that I have these awful symptoms. The first three weeks I was at 0.25, I found by week 3 they were milder symptoms, but this week I have increased to 0.50, and I am extremely sick with nausea and headache. I've found the GI issues mild, but I am on other medication that constipates me. I feel this may have been worse otherwise. I am going to tough it out for the next few weeks until I get to 1, as I found a decrease in the nausea over the first three weeks until I increased the dosage. However, if this is a constant side effect, I will 100% be discontinuing this medication."

• Hoo...
• May 17, 2018

For Type 2 Diabetes "Initially began Ozempic 0.25mg for 4 weeks. Side effects were tiredness, constipation. My fasting blood sugar numbers were lower in the morning. When I began the 0.50mg dose at 5 weeks, I had nausea, dizziness, and lethargy the day following the first dose. The second day following that dose, I felt about 70% better. With the second dose of 0.50mg, side effects were less severe, some minor nausea, headaches, and the tiredness continued. I hope that these side effects disappear. I plan to take this medication until I get my 3-month labs, and I expect that my A1c will be down significantly. It was at 5.9 in July of 2017. Due to the stress of caring for a dying relative from September through December, it jumped to 9.3. At my next appointment, my doctor suggested I try Ozempic in combination with Metformin 500mg twice a day. I received a 3-month discount card and have not yet checked with my health insurance provider to see if it will be covered. I am an active 61-year-old female, but type 2 diabetes does run in my mother’s family."

• Kel...
• Taken for less than 1 month
• August 20, 2021

For Cardiovascular Risk Reduction "Was Ozempic for 4 weeks. Giving myself a weekly injection. Week 1 and 2, I was okay. The end of week 2, I was really nauseous. By the 3rd week, I couldn't eat or drink anything. My prescriber assured me I would be okay, so I went on with my 4th week. I spent 3 separate days in A&E, and I was diagnosed with a clot in the lung (PE). Now, maybe this wasn't directly caused by the injection, but due to the severe nausea and dehydration, that is how I got a clot. The nausea still continued for 4 weeks after my last injection. I would never recommend this at all. If my clot hadn't been picked up, goodness knows what may have happened. I also had bad dizziness and severe headaches."

• Poi...
• Taken for 1 to 6 months
• February 14, 2022

For Cardiovascular Risk Reduction "This drug is absolutely awful. I had horrible nausea from the beginning, along with vomiting and headaches 5 out of 7 days a week. I kept being told side effects would get better, but they just got worse. This is my 5th and final month on it. I literally don't remember the last time I was able to eat. 6 of the last 10 days, I wasn't even able to keep liquids down and became severely dehydrated. I had the absolute worst headache of my life. I've lost 12 pounds in 9 days, and not one pound of weight loss is worth it. I wake up in the morning wishing I'd just die instead of having to feel as awful as my body does every day. I took my last dose 10 days ago, so I'm praying this poison gets out of my body ASAP. This stuff is toxic."

• Cap...
• Taken for 1 to 6 months
• May 12, 2021

For Type 2 Diabetes "I took Ozempic last October, but I had to come off it - I was so ill. I'm type 2 diabetic and Hashimoto's thyroiditis autoimmune disease. I'm 57 years old and post-menopause. The doctor decided I should try again, I started 5 weeks ago and had my 5th injection. I have been sick since I restarted. I have nausea, vomiting, diarrhea, brain fog, anxiety, burning in my stomach, headaches, and I'm so tired and weak. I tried to stick with it, I'm on the 3rd day since my 5th injection. I am so ill, I still have all the above symptoms, but worse. My kidneys are sore and my lungs. I have pain in my stomach and back. I feel like my body is poisoned, and I have to wait for 5 weeks for it to clear out of my system. I will never take this again."

• Oh-...
• Taken for 1 to 6 months
• June 3, 2022

For Cardiovascular Risk Reduction "A little background: I am 6'2", 24 years old, and the most I ever weighed was 316 lbs. Always used to wear the baggiest clothes and was not confident in myself. The crazy thing is that it was a “trim” 316 lbs (if that makes sense), like, I play hockey and get around just fine - I was just overweight. In college, I managed to get down to 280 from being poor and walking everywhere. But now I am in the real world working, and about 4 months ago, when I began Ozempic, I was back up to 310 lbs. My mom started it, she liked it, she was down about 10 lbs and told me I should try it. I started at .25 for about 6 weeks. I had not lost much weight in the beginning and had some nausea and pretty decent headaches, but that goes away after about a week or so. I am now taking the 1.7 Wegovy, and I am now down to 265. I feel great, look great, and I look forward to taking the 2.4."

• Ice...
• Taken for less than 1 month
• November 4, 2019

For Type 2 Diabetes "OMG ... it’s not me. Dr. started me at .5 of Ozempic, first day after injection pretty much okay, then came nausea, stomach ache, headaches, then just dulled, gassy (didn’t know the burps were part of it but that increased), diarrhea, feeling beyond blah. I went to work and struggled through the day for 4 days like this. The first week wasn’t sure if it was the shot or some food, so I tried the Ozempic again. The second week was a little better, so I decided I’ll try the smaller dose. Today is day 2, but this morn, there’s the nausea, stomach ache, a little bit of headache, but lesser amounts. Despite the thought of weight loss, might be heading back to Januvia (Farxiga got the yeast infection, but it was cheap, $15 for 90 with insurance)."

• Anonymous
• Taken for 1 to 6 months
• May 8, 2022

For Cardiovascular Risk Reduction "I did not like the side effects that I experienced while taking Ozempic. The first day I was on Ozempic, I had severe vomiting. Although I did not continue to vomit, I did feel nauseated and not well the 4 months while on Ozempic. I also started experiencing severe headaches, and my sinuses became very dry and hurt. I then lost my sense of taste and smell. I stopped taking it right away. It has been more than two years since I last took Ozempic and still cannot taste or smell. I would not recommend this drug to anyone."

• And...
• Taken for less than 1 month
• October 18, 2019

For Type 2 Diabetes "I started Ozempic injections 3 weeks ago (by the way, I live in the UK). I also take Metformin and Foxigra. I had a slight headache and nausea, which I seem to get a few days after the injection. I don't find I get any appetite decrease that much, and I've put on weight this week. But sticking with it, so we shall see."

• Wri...
• Taken for 1 to 6 months
• August 21, 2021

For Type 2 Diabetes "I have been taking Ozempic for 10 weeks for both weight loss, which I have struggled with for years, and diabetes. I experienced nausea, constipation, slight dizziness, and headaches, but nothing that I couldn't manage, and only for 1 or 2 weeks of each increased dose. Went from 0.25 to 0.5, and now I'm on week 2 of the highest dose, 1.0, and currently have no side effects. I have also lost 19 lb so far, the doctor advised a 1200-calorie diet, and I couldn't be happier. My blood levels have come down from high 7's to 6.4, and the doctor is considering taking me off my usual diabetic medication, Empagliflozin. Some folks are saying, 'don't take it,' but just because their body didn't take to it doesn't mean you won't! And you could be missing out on what I would say is a game-changing medicine. I would say give it a go. And I wouldn't give up now for anything. My health has significantly improved. (Free to diabetics in the UK)."

• Jea...
• Taken for less than 1 month
• June 7, 2023

For Type 2 Diabetes "Nausea, bad acid reflux at night, nightmares, headache every morning, constipation, chills, fatigue. Just started a week ago. Blood sugar levels in the 80s and 90s. Have lost no weight. Zero appetite. Blurry vision."

• hal...
• Taken for less than 1 month
• June 4, 2023

For Type 2 Diabetes "The major side effects are all I got with this med, which includes upset stomach, heartburn, burping, gas, bloating, nausea, vomiting, stomach pain, loss of appetite, stomach flu symptoms, headache, dizziness, and tiredness."

• Wen...
• Taken for 1 to 6 months
• March 8, 2022

For Type 2 Diabetes "I have been on Ozempic at the lowest dose for 4 weeks. The first week was brutal, with stomach pain, nausea, vomiting, and headache, however, I injected the second week in my thigh and the side effects waned. It appears to be lowering and leveling my A1C. I'm nervous about increasing my dose next week. I can manage a week of discomfort as long as it is short-term. My body does seem to be getting used to it. I'm willing to work with it as long-term benefits for me outweigh the short-term discomfort. I may change my mind as time goes on, as these horror stories have me concerned. So strange that there is such a wide range of patient experiences...both good and bad."

• Fro...
• Taken for less than 1 month
• December 13, 2021

For Type 2 Diabetes "My doctor prescribed it as a miracle drug, bought a 0.25 mg kit. My doctor gave me instructions, but I found better instructions on YouTube, so the next day I was ready with all that info. I cooked a light soup, no carbs, no fat, etc. I drank water, washed my hands, cleaned my belly, and did the shot. All was okay. After a few hours, abdominal pain, my eyes started to itch, then blurry vision. I went crazy, wondering what happened to me, went to bed, then the nausea came with a headache. The next days I was sick and did not go away, so I phoned my doctor. She said it's all in my mind and I will get used to it. Now I am afraid of the second injection, is it worth it? Why pay for an expensive drug to get sick? The only positive was that it lowered my morning blood sugar from 100-110 to 88. I take 1000 mg of metformin twice a day. For others, do not use it for the first time and go to work, it's good to do it when you do not have work the next day."

• Jul...
• Taken for 1 to 6 months
• March 10, 2022

For Type 2 Diabetes "Newly diagnosed with type 2, started with .25 for 5 weeks. Lots of waves of nausea, headaches, and overall discomfort. Week 5 did get better, the side effects lasted just a day or two after injection. .5 has been a 2-week nightmare. Extremely painful headaches, nausea, and now constipation. I am hoping there's a different med I can try that isn't so hard."

• Jul...
• Taken for 1 to 6 months
• March 10, 2022

For Type 2 Diabetes "Newly diagnosed with type 2, started with .25 for 5 weeks. Lots of waves of nausea, headaches, and overall discomfort. Week 5 did get better, the side effects lasted just a day or two after injection. .5 has been a 2-week nightmare. Extremely painful headaches, nausea, and now constipation. I am hoping there's a different med I can try that isn't so hard."

• not...
• Taken for 1 to 6 months
• May 3, 2023

For Type 2 Diabetes "I unfortunately had a very severe reaction to Ozempic. I usually do suffer side effects from most medications, but thought I would give it a try. The first two weeks were headache, general stomach ache, and constipation lasting 2 days after each injection. Weeks 3 and 4 got worse. Stronger reactions, lasting longer. Week 5, I started the double dose, and I was pretty ill for 2 days. Week 6 and 7 was rough, but I thought I could ride it out. Week 8 had me in emergency twice for diarrhea, vomiting, headache, and major dehydration. I was unable to eat or drink anything. I had to get rehydrated and be given anti-nausea meds on both occasions. I guess my body slowed the release of food so much I had a massive buildup to the point even a sip of water made me extremely nauseous. Ozempic is not for me."

• Meg...
• Taken for less than 1 month
• March 16, 2021

For Cardiovascular Risk Reduction "I started this medication last week on Tuesday. The first two days, I had a headache and a flu-like feeling. Throughout the week, I felt nausea almost daily, bouts of diarrhea, and bloated. Today is my second dose of 0.25, and I lost 4 pounds in 7 days (probably the fact that anytime I eat, my next bowel movement is diarrhea). I have felt a general unwellness for the last 7 days and am anxious about how this week will go, as I haven't been able to accomplish what I normally am able to. If this week gets worse and I start vomiting and being really unwell, then I will stop taking this medication. I definitely don't have the same appetite I did before, and my junk food craving has basically been vanquished, however. If the symptoms don't peter out or they get worse, I don't see the point, as it affects my son's life as well when I can't be the best mom I can be."