Semaglutide for Type 2 Diabetes User Reviews (Page 5)
Brand names: Ozempic, Rybelsus, Wegovy
Reviews for Semaglutide
- Jer...
- Taken for 1 to 6 months
- June 20, 2023
"It was a disaster for me. My A1C used to stay between 7.5 and 8.5, and morning fasting readings were high, like 130 to 160. Increasing Glimepiride from 4 mg up to 8 mg didn't work. My doctor started me on 3 mg/day of Rybelsus. It caused constipation, upset stomach, and a lot of burping. But morning fasting readings came down to around 100, so I was tempted to try it out. After finishing the 3 mg dose for 30 days, I started taking 7 mg/day. My symptoms worsened: constipation, loss of appetite, noisy stomach, lots of burping, GERD, and weight loss from 152 lbs to 139 lbs in just about a couple of months. I could not afford to lose any more weight. I also saw some foamy urine indicating it was affecting my kidney function too. I stopped taking Rybelsus under my doctor's advice, and since then, the constipation is gone, the burping is gone, the appetite is good, and life seems back to normal. I still need to check on my kidneys for any issues since foamy urine is still there. The last A1C was 7.9."
- Ran...
- Taken for less than 1 month
- September 21, 2020
"I've been taking Ozempic for two weeks now. I wondered how this drug could allow some - or most - people to lose weight. Now I know - it makes you feel sort of sick to your stomach and takes away your appetite - at least that is my result so far. I am hoping to develop a tolerance to it. Not a really pleasant experience so far, but I have not vomited or had diarrhea as some users have reported. It does appear to be lowering my blood glucose somewhat, which is the primary reason I am taking it. I am also taking metformin but have been able to reduce the dosage. I am still only taking 0.25 mg of Ozempic, so the result of higher dosages is unknown now. I will post again in a month or two with higher dosage usage results."
Frequently asked questions
- Ozempic Side Effects to Watch For
- Wegovy vs Ozempic: Which is Right for You?
- Tirzepatide vs semaglutide: How do they compare?
- Why am I not losing weight on Ozempic?
- OZa...
- Taken for 1 to 6 months
- November 14, 2019
"I have been on Ozempic (semaglutide) for 7 weeks and am presently on 0.5mg dose. Positives - I have lost 15 pounds, my A1c has dropped from 6.8 to 6.0. I feel great. Negatives - Blood level dropped fast with the first shot, after that no issues, slight nausea right after the shot. It doesn't last more than 30 mins. Positives outweigh the negatives IMO."
- SSH...
- Taken for 1 to 6 months
- February 25, 2020
"I have been on Rybelsus for 2 months. I started on the 3 mg and did fine, no side effects, and actually felt more awake and focused. Then I went to the 7 mg and was very nauseous and vomited almost nightly. It felt like my food never digested. I apparently am pretty sensitive to this medication and since my blood glucose and A1C have been good, I am taking this every other day, which has lessened the nausea and discomfort. I have lost 6 lbs in the past month and that has been great because I needed that. So we will see how this continues, but I feel pretty good."
Are you taking this medicine?
Your review helps others make informed decisions.- CSC...
- Taken for 6 months to 1 year
- November 9, 2020
"The first few weeks I suffered some nausea, and my food intake was reduced probably about 30% as a result. I started at 0.25 for a month, then 0.50 for a month, then 1.00, which was the full dose. I have been on the drug for about 6 months now. My weight dropped 30 pounds from 264 pounds to 234 pounds, and I seem to be leveling at that range. My target BMI weight for 6 feet 3 inches is 210, but I would be happy at 225. I have found that Ozempic did cause some constipation, but overall, once I achieved the full dose for a few weeks, I felt much better. The weight loss has really helped how I feel, and I will be doing my 6-month blood workup next week. Hoping to see some good results with glucose, which was at 6.0, and cholesterol at 259. Overall, I am very happy with the results to date."
- L0v...
- Taken for less than 1 month
- March 14, 2020
"Second day on Rybelsus 3 mg. I was too afraid to try it, but I'm glad I did. No side effects at all except for the loss of appetite. I will return and provide an update. I need to lose 60 lbs. I have tried Victoza and Invokana and got very sick within the first couple of days of taking them, so I hope Rybelsus is the answer for me. I exercise and watch my diet, but my glucose levels were still too high."
More FAQ
- How does semaglutide work for weight loss?
- How much does semaglutide cost?
- Where and how should Ozempic be injected?
- Does Ozempic cause muscle loss and how to prevent it?
- mar...
- Taken for 1 to 6 months
- July 3, 2023
"The side effects of my gastrointestinal symptoms have made this drug intolerable to me. While my A1C is now down to 6.1 from 7, at my age, 7 is still considered an acceptable result. So in my estimation, it has not been worth the severe cramps, diarrhea, headaches, blurred vision, and dizziness I have experienced."
- JJa...
- Taken for 1 to 6 months
- April 29, 2021
"This is the first medicine I've used that has actually helped me lose weight. I take a bunch of psych meds that have packed on pounds (Seroquel). I started with the 3 mg titrating package and had slight heartburn for a few days. By the end of a month on 3 mg, I lost ~6 lbs. I had slight nausea at first on the 7 mg dose (after a month on 3 mg), but that faded. Now, after a month on 7 mg, I'm down a total of 14 lbs total (233 to 219). Before this med, I've been trending only upward for the past 4 or 5 years. I'm super stoked that I might be able to see under 200 lbs again in a few more months."
- Lor...
- Taken for 1 to 6 months
- March 13, 2020
"I've been on Ozempic for 2.5 months now (10 weeks as of today) off-label for PCOS. I started with a dose of 0.25 for the first four weeks and have been on 0.5 for the remaining six. On the 0.25 dose, I felt my appetite was slightly reduced, and I had some mild nausea. As soon as I went to 0.5, the side effects started, and I began getting extreme nausea, diarrhea, rancid burps, and I can no longer eat. If I eat more than a regular ham and cheese sandwich in a day, I feel extremely nauseous and the burps come back. As of my last doctor's appointment, I've lost about 3 pounds, but I don't know if I can keep this up. I'm miserable. I won't know until next month whether it's working like my doctor has intended because she needs blood tests to verify all of that, so I can't speak to how effective it has been yet."
- Bir...
- Taken for 1 to 6 months
- August 12, 2020
"Bad news: I started taking the 3 mg Rybelsus for 30 days, did well. Have been taking the 7 mg for the past 3 weeks, and I have had diarrhea, stomach bloating, nausea, and can barely eat anything or drink. Even the smell of food makes me sick. I am extremely exhausted and hate feeling like this. Calling doctor tomorrow. Good news: dropped A1C from 8.4 to 7.3 in 6 weeks and lost 10 pounds, and also cut back on my 24 hr insulin and fast acting due to not eating. — Is it really worth it though???"
- Iri...
- Taken for 6 months to 1 year
- October 12, 2019
"I started Ozempic in March 2019. This allowed me to quit taking Actose and Glipizide. I weighed 287 lbs., and my A1C was 7.8 and rising. I was a little nauseous for the first week, and then it subsided. I haven’t experienced any since. Now in October, I weighed in at 231, and my A1C is down to 6.2. My energy is up, and I feel great. This medicine definitely improved my quality of life. I’ve never gone beyond the .5 dosage, and my endocrinologist said that an increase is not necessary for me. I would recommend everyone give it a chance. I know it won’t be for everyone, but if it works, your daily life will change for the better."
- Bak...
- Taken for 1 to 6 months
- May 24, 2019
"I have been on Ozempic for 3 months now, and I find this drug works like none I have tried before. The first 6 weeks were rough: burping, headaches, fatigue, nausea, but I stuck it out. I’m so glad I did. My A1C has gone from 8 to 6.8 in three months. I have lost 20 pounds, going from 180 to 160 lbs. My daily sugars have seen a vast improvement. The major thing I have noticed after being on the drug for this long is that recovery time after eating high-carb or high-sugar foods is back to normal. Appetite is still lacking, but it’s mostly an aversion to ‘bad’ food. I can no longer sit and eat an entire burger, it’s just way too much, but a healthy salad, I can eat the whole thing! I have seen major benefits from this drug. I have way more energy and no more 3 pm crash. Tips while adjusting to the drugs: Tums, Gravol, lots of sleep, light healthy meals, and remember to drink water! Also, I found injecting Ozempic in the hip lessened the symptoms for the first while."
- New...
- Taken for 1 to 6 months
- August 21, 2020
"I was moved to Ozempic from Januvia. At the time I started Ozempic, I'd brought my blood sugar down to what would translate to an A1C of 5.5 or so, and I'd managed to kick most of the insulin I was on. I started Ozempic at 0.25 units per week and had mild nausea and diarrhea, but my appetite vanished and I could barely bring myself to eat. Once I started the full dose, my blood sugars began to climb rapidly. I'd be fine in the mornings at first and then experience wild spikes between meals, until finally, my fasting sugar started to climb out of my desired range. I actually had to take MORE insulin, not less, just to keep my fasting BG below 7. Ozempic was absolutely NOT worth it - even with the lower price here in Canada, the cost is ridiculous, the benefits never materialized, and the effects on my appetite destroyed the healthy diet I was trying to eat. Good example of how new isn't always good."
- Ano...
- Taken for 1 to 6 months
- March 28, 2025
"I started in 3 mg, now in 7 mg. My blood sugars have come down enormously, I have lost about a stone in weight after being on it for 4 months. You must take it first thing with just a dash of water, don’t eat or drink for half an hour. The side effects are a bit brutal but do die down, bit of constipation and food suppression. Feel better than I have in a long while on this tablet."
- Sun...
- Taken for less than 1 month
- March 8, 2020
"I started Ozempic on Friday. I'm hoping the side effects go away because it has helped my blood sugar readings and helped with cravings. The side effects I'm having are horrible diarrhea, joint and muscle pain, and fatigue. I don't know how long these symptoms will last, but hopefully not long."
- Cta...
- Taken for 1 to 6 months
- December 8, 2019
"I was on Ozempic .5 for 6 months. During that time, I had severe stomach cramps and diarrhea. My blood pressure went out of control, causing my vision to double. I have 6th cranial nerve palsy caused by a spike in blood pressure. EKG now shows I have a right bundle branch blockage and may need a pacemaker. I never had anything like this before. I have had the same doctor for 15 years, and he is also concerned. I believe Ozempic is the root cause, my eyesight may not get completely normal. Will be getting legal advice."
- Rit...
- Taken for 1 to 6 months
- January 17, 2020
"For the first three weeks on this drug, I had oscillating constipation and diarrhea. I felt very nauseous and did not want to eat much. After upping the dosage, the digestive problems have decreased, but I still feel nauseous and don't have much of an appetite. I have been on it since November and have lost 16 lbs. with Metformin, diet, and exercise."
- Cla...
- Taken for 1 to 6 months
- December 12, 2020
"I just got my A1C after 3.5 months on Rybelsus (one month at 3 mg and 2.5 at 7 mg), and I’m very excited that it’s dropped from 7.8 to 6.5! I have had some side effects - mainly stomach pain, gas, and occasional constipation - but the results are worth it. I haven’t had any significant weight loss, but my BMI was under 27 to start with, and because we had Thanksgiving recently, I normally would have gained a couple of pounds. If you have just started and are having side effects, try to hang in there. The first month was the worst for me."
- agg...
- June 7, 2021
"I started taking this 3 weeks ago. I didn’t really have any terrible side effects other than fatigue, but after my third injection, nausea, diarrhea, and stomach pain hit me with a vengeance. I feel like I ate rotten eggs. I’m not sure I want to continue taking this. I might try injecting it in my thigh like some others have tried. I hope it works because my glucose readings have been in the 90s to 120."
- MIC...
- Taken for 1 to 6 months
- November 5, 2020
"A1C was 6.2 with Metformin. Went on Ozempic for 3 months. I had side effects of bad nausea, vomiting, and watery diarrhea. Lost 27 lbs. Couldn't eat 4/7 days. My A1C now 5.6, and it is not worth it for me."
- Bon...
- Taken for 1 to 6 months
- July 13, 2021
"Started Ozempic about 7 weeks ago. Dosage .25. First week noticed some nausea, a lot of gas, some reflux, and diarrhea. Each week, side effects were getting worse. Nausea very bad, pains in left side, waves of heat, no energy at all. In all, just feeling BAD! Diarrhea is bad and a bit uncontrollable. Have not raised dosage due to being afraid of worse side effects. Have lost 5 pounds. Appetite is definitely less. My sugar numbers have not improved that much, which leads me to believe it is what I am eating. I still crave sweets. I have some jittery feelings at times! I am very discouraged."
- Mar...
- Taken for 1 to 6 months
- July 14, 2021
"Started taking Ozempic back in February after I asked my doctor to put me on it because of reading a British study on weight loss by semaglutide. Started at the 0.25 mg level for three weeks. Went to 0.50 for another four weeks and have been on 1 mg thereafter. No serious side effects apart from some belching, acid reflux after bedtime, and rare diarrhea. Significant loss of appetite, change of taste in foods, change of perceived texture of foods, significant reduction in alcohol enjoyment and intake, and increased sensitivity to cold. My A1C has gone from 6.7 to 6.0, and I have lost over 35 pounds since the start. My cholesterol is down to 115 and LDL down to 50, something I have never seen before. Overall, the results far outweigh the downsides of this drug and it has provided the most positive results faster than any other medication I have tried before."
- Car...
- Taken for 1 to 6 months
- March 19, 2022
"Using Rybelsus was a nightmare for me. I have insulin resistance, and my doctor wanted to bring my A1C down below 6. First, it caused me to gain 10 lbs while I was on the 3 mg. I thought once I started the 7 mg, the weight would finally start to come off. Nope. If that wasn't bad enough, I was lucky enough to experience one of the rare side effects... nerve damage. My left leg started feeling like I had sciatica. It got a lot worse from there. Nerve damage not only affects the damaged area but your brain as well. It took about 4 months before I began to feel normal. I had quit the Rybelsus as soon as I realized what was happening to me. My annual family vacation was ruined. I had an extra 10 lbs on me. I couldn't drive for a couple of months, and my brain was seriously affected. Oh yeah, and nerve damage is like pain I never felt before, and I've given birth twice. I'm glad for the folks helped by this. It sure didn't work out for me."
- Big...
- October 7, 2020
"I started taking Rybelsus for weight loss. I was 326 lb. Now that I have been on it for a month, I have lost 8 pounds. I’m 318 lb currently. I have had absolutely no side effects. I’m a 6’1", 22-year-old male. I am not sure if that factors into anything. Anyway, tomorrow I’ll be starting to take 7 mg, then hopefully next month 14 mg, and so on."
Are you taking this medicine?
Your review helps others make informed decisions.Learn more about Type 2 Diabetes
- Diabetes Medications and Alcohol Interactions
- FDA-Approved Weight Loss Drugs: Can They Help You?
- OneTouch Blood Glucose Meters
- Side Effects of Weight Loss Drugs
- Top 10 Diabetes Treatments You May Have Missed
- Which Drugs Cause Weight Gain?
Care guides
- Diabetes and your Skin
- Diabetic Gastroparesis
- Diabetic Hyperglycemia
- Diabetic Kidney Disease
- Diabetic Neuropathy
- How to Draw Up Insulin
- Hypoglycemia in a Person with Diabetes
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"I've been on Rybelsus for eight months, and I have lost about 34 lbs. I started on the 3 mg dosage, and after two months, moved up to 7 mg, where I have stayed. However, one of the major side effects is slowed gastric emptying, which can lead to extreme stomach pain if you make the mistake of eating too much in a day. After a couple of bad episodes, I had an endoscopy just to be sure nothing else was wrong - but ultimately, my gastroenterologist said that it's just the effect of Rybelsus."