Semaglutide User Reviews & Ratings (Page 3)
Brand names: Ozempic, Rybelsus, Wegovy
Semaglutide has an average rating of 6.9 out of 10 from a total of 2,592 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 21% reported a negative experience.
Reviews for Semaglutide
- Mil...
- Taken for 1 to 6 months
- December 9, 2021
For Weight Loss (Obesity/Overweight) "I started Wegovy at the end of July 2021. I was up to the second dose amount. I stopped it on October 8, 2021, because I was experiencing extreme hair loss. I had called and spoken to a Wegovy representative the month before about it, and they said someone was going to call me, as this was not a side effect that they knew of. No one ever called. I did look on another site, and it did show hair loss. Knowing that hair loss with this product is real. It has been a very depressing time for me as the way I look at myself has changed because of the loss of my hair. HAIR LOSS IS REAL WITH WEGOVY"
- Sno...
- Taken for 6 months to 1 year
- July 16, 2019
For Type 2 Diabetes "Side effects are mild for me, but it really decreases your appetite. Initially, I could only tolerate fresh fruits and vegetables. I took this as an opportunity to change my lifestyle. I eat healthier and avoided sugary drinks. I lost a total of 40 lbs. in 6 months. A1C dropped from 7.3 to 5.4. Dress size dropped from 14 to size 4. I am no longer on daily insulin, BP meds, and cholesterol meds. All labs are normal. This medication is my lifesaver."
Frequently asked questions
- Ozempic Side Effects to Watch For
- Wegovy vs Ozempic: Which is Right for You?
- Tirzepatide vs semaglutide: How do they compare?
- Why am I not losing weight on Ozempic?
- Gum...
- Taken for 1 to 6 months
- February 28, 2020
For Type 2 Diabetes "I’ve been on Rybelsus since 1 December at a dose of 3 mg. January 1, I started 7mg. I don’t like taking medication and was scared of this medication due to other reviews I have read. I am very pleased with the outcome. I lost 5 lbs with very little exercise. My side effects were nausea and loss of appetite. Nausea only occurred when I ate junk food and sweets. A1c down from 7 to 6.2. Plus, I do not take any other meds for diabetes. Hope my review will help others. February 28."
- Lyn...
- December 22, 2020
For Type 2 Diabetes "I took one dose of Ozempic and I have been sick ever since. Diarrhea, vomiting, nausea, stomach cramps, and a little dizziness. This is terrible, will never use again. Can someone tell me how long these symptoms last?"
Are you taking this medicine?
Your review helps others make informed decisions.- Lif...
- Taken for 1 to 6 months
- May 10, 2023
For Weight Loss (Obesity/Overweight) "So far, after 4 months, this has helped boost weight loss. At 57, I’ve been battling with the slowest metabolism on earth! It didn’t matter what I ate, when, how, how much, nothing. I started an exercise program that I promised myself I would stick with for a minimum of 2 months and I did it like an adult. Meaning I didn't work out for 3 hours my first time. After 4 months, I’ve lost 50 lbs, again, I added exercise prior to starting Wegovy because I had both knees replaced. I will have nothing else replaced due to being overweight. I, personally, have had NO side effects except I’m not hungry at all. But this allows me to make better choices. Best of luck to all!"
- Ail...
- Taken for 1 to 6 months
- January 4, 2021
For Cardiovascular Risk Reduction "I went on Ozempic for weight loss after being told by a friend of mine about it - she started at 280 lbs and lost 60+ pounds. My whole life I’ve always been about 130 pounds, and then I rapidly gained 50 pounds within about 2 years. I started taking Ozempic at 182 pounds (I’m 5’4) and 6 months later I am down 25 pounds and continuing to lose. I could not recommend this drug more. It INTENSELY reduced my appetite and obsession over food. Aside from some occasional nausea (maybe once every 2 weeks), and some diarrhea, nothing that I can’t handle, the drug has been pretty great. This is only my experience though!"
More FAQ
- How does semaglutide work for weight loss?
- How much does semaglutide cost?
- Where and how should Ozempic be injected?
- Does Ozempic cause muscle loss and how to prevent it?
- Anonymous
- Taken for less than 1 month
- January 22, 2022
For Weight Loss (Obesity/Overweight) "Worst experience of my life. After the second 0.25 dose, I was up all night vomiting and diarrhea. The next day, I had chest pain, shaking, brain fog, stomach pain, more diarrhea, and had to go to the ER. After they gave me Benadryl and morphine, I started to feel better. Still have burping, gas, and acid reflux terribly. WILL NEVER TRY THIS AGAIN! It is not worth it to me! Wish it would hurry up and get out of my system."
- Mim...
- Taken for 1 to 6 months
- July 7, 2023
For Weight Loss (Obesity/Overweight) "Since my first injection, I have felt utterly dreadful. The nausea is one thing, but I have constant fatigue that prevents me from leading my normal life. I know it suppresses appetite, but I don’t have ANY appetite at all and cannot face food. I know if I eat, I will feel a bit better, but it’s impossible. I actually feel like I’ve been drugged. Yes, the ‘food noise’ has gone, and I no longer overeat or binge, but I feel like everything is suppressed - like I’m on a strong drug. I did 4 weeks at 0.25 and have just done one week at 0.5, but I can’t do this anymore. I feel utterly dreadful. I am so pleased it’s helping so many people, but more research is needed into why some people just can’t tolerate it."
- Koo...
- May 1, 2021
For Type 2 Diabetes "I have been taking Rybelsus for 6 months. At first, I was nauseous and had bad sulfur burps, but it went away. My A1C is the best it's been in 9 years. I have had a hard time treating my diabetes, as most other oral medications and daily injections just made life harder. Now, my numbers are 6.7, and I have lost a significant amount of weight, 335 lb to 285 lb, with minimal effort. It definitely suppresses my appetite. I've read you can only lose a few pounds, but I feel like a lucky one."
- She...
- Taken for 1 to 6 months
- September 4, 2020
For Type 2 Diabetes "I've been on Ozempic for 8 weeks. At first, I had side effects of a lot of nausea. Now, I wake up cold and clammy the last week and very anxious. Overall feeling unwell. Wondering if anyone else has experienced this?"
- Bo ...
- Taken for 6 months to 1 year
- February 28, 2022
For Weight Loss (Obesity/Overweight) "I started with Ozempic (which is the same thing, I think) for assistance with diabetes. In the first year, I lost fifty pounds, I became more capable of moving better, and I started. In February and March of the second year, I was hospitalized twice for massive blood clots in my right thigh and the Wegovy was put aside for a couple of months. In April of 2021, my endocrinologist asked me if I would like to switch to this new version that might give me a boost. Sure, why not. I started with the lowest and immediately moved to the 2.4 doses. I have had no side effects no problems with the injection sites. The only issue has been obtaining the medicine. Oh, health changes. Within the first year of the Ozempic, my A1c went from 8.1 to 7.3, in the second year it has dropped to 6.1. My blood glucose averages are about 130, I can live with that! I have to be careful with going too low! Total weight loss is hovering between 95 and 100 lbs."
- Chr...
- Taken for 1 to 6 months
- July 11, 2021
For Type 2 Diabetes "I suffered from - Loss of appetite - Exhaustion - Nausea - Vomiting (once a week, usually 2 days after my injection) - Low blood sugar events (probably caused because I just had no appetite). When I spoke to my pharmacist, she encouraged me to try to hang in there, telling me it would get better, and it finally has. I was not expecting it to take over 3 months though. My readings are all good, and I've lost 28 lbs, so there were benefits to sticking it out, but it was hard. I had decided that I would continue to take the medication until my next appointment, and if things were still bad, I would tell the doctor that I no longer wanted to use it. Things are better, and my appointment is next week."
- Ama...
- Taken for 6 months to 1 year
- December 16, 2021
For Type 2 Diabetes "Listen to me, Ozempic will change your life, but you cannot eat synthetic sugar at all. I had severe Hashimoto's, PCOS, insulin resistance, and severe diabetes symptoms. HbA1c was high, all cholesterols were high despite the healthiest of diets. My numbers cleared from severe to perfect in 1 month! I had full-body swelling, severely cracked ankles, swollen feet, neck, legs, major hair loss... a nightmare. I began taking Ozempic. I was very sick. It made me extremely nauseous. I got severe diarrhea, but let me tell you, I lost 17 pounds of water weight in one month. My doctor couldn’t believe it. In four months, I lost 40 lbs. The nausea was mild to severe the entire time, but the results were borderline insane. It reset my metabolism, took all of the inflammation away from my joints, neck, back, my feet completely healed within one month. It’s barely believable. I spent two months on 0.25 and increased to 0.5 once a week for ten more months. High praise!"
- Con...
- Taken for less than 1 month
- March 26, 2023
For Type 2 Diabetes "I took 3 mg of Rybelsus for about two weeks. I noticed right away that I was not able to poop normally. I thought constipation would resolve naturally since I don’t have issues with it normally. Now, I’ve been off of it for a week and I’ve had two ER visits because I can’t poop. I also struggle to pee because the thought is the backed-up poop is pressing on things it shouldn’t. Had to have a catheter drain me out. I did a week of Miralax, two days of Dulcolax, one ER cocktail, and an enema, and none of it has helped. At this point, I’m scared it will take surgery to remove the poop. If you’re taking this medicine please stay in tune with your body and mitigate early if you’re starting to experience any constipation."
- Bmi...
- Taken for 1 to 6 months
- December 28, 2021
For Weight Loss (Obesity/Overweight) "I feel completely normal with regard to appetite. I hardly think of food and never finish my plate. I definitely needed the Zofran script - I found the first two days were the most difficult. Definitely losing weight, which makes it easier to do gentle stretching to prepare for more walking and stairs. Fear is alleviated…hope is restored…I have control, therefore, the ability to make healthier food choices and increase exercise. Not for everyone, definitely for me."
- Lem...
- Taken for 1 to 6 months
- February 1, 2021
For Type 2 Diabetes "Honestly, I am so impressed so far with these meds. My weight had been creeping up due to insulin resistance (which itself makes it harder to lose weight) and PCOS. My doctor recommended I try this in conjunction with a very low carb and calorie diet. I started with a half dose of 0.25mg once a week injection and then after 2 weeks up to 0.5mg a week. So far in 6 weeks, I’ve lost 15cm from my waist and 9cm off my hips, and 5cm off my bust. I have been eating light and easy, roughly 1000 calories a day. Haven’t weighed myself yet as I’d prefer to see the difference in cm. This medication makes me feel a little nauseous the first day or two after my shot, but after that, I never feel hungry. I can quite easily eat a super small portion and feel full! I drink about 2L of water a day and do about 8000 steps at my job. It really has been great and so much cheaper than Saxenda, which was another one I was considering. Hopefully, I continue to lose weight!"
- Mar...
- Taken for 6 months to 1 year
- April 27, 2020
For Cardiovascular Risk Reduction "Unbelievable medicine - although I was supposed to start with a 0.25 dose and move up to 0.5, I never did. I have stayed on the 0.25 dose and feel amazing. I have lost 30 lbs, don’t have any bad taste in my mouth, no bloating or excess gas. Actually, I can’t find anything bad to say about this medication other than it is expensive. I feel better than I have in years, and my A1C is unbelievable! Keep it up but please make it cheaper!"
- Sks...
- Taken for less than 1 month
- May 25, 2023
For Weight Loss (Obesity/Overweight) "I never leave reviews and rarely have side effects from medication. However, after one injection on the lowest dose, I am so beyond sick. Two days after my injection, I got a migraine followed by extreme vomiting for 4 days, chills, nausea, and a trip to the ER. This medication made me so unbelievably sick, it is like I've been poisoned. I have missed 4 days of work and am so weak. Living on Pedialyte and numerous nausea medications. Please be so careful. I was so hopeful and had no idea this would happen to me."
- lei...
- May 19, 2021
For Type 2 Diabetes "I've been on it for 7 weeks. I have had the runs as others have noted, and the sour stomach, but what I also noted is that those symptoms are worse if you've eaten too much or a heavier meal before bedtime. Small snacks are ok. I don't drink any sugar-laden beverages, and I eat lots of fiber already. My diet is mostly vegetarian, but not for any reason other than my stomach just feels better on it. I think that has helped keep the side effects in check. So far, I've lost 8 lbs, which TBH is kind of shocking. I never thought my body would give up this weight, but I'm heading in the right direction. Sugars are dropping nicely, especially my fasting sugar. I have that hypo drop and spike when you wake up, and that seems to be leveling off, which is great. So I'm going to keep going. Oh, and I didn't jump in with dosing, I started with 0.25 and kept on that for six weeks and only just now moving to 0.5. Slow gradual is the right way. Too much at once will make you sick."
- Kri...
- Taken for less than 1 month
- August 23, 2018
For Type 2 Diabetes "I have been on Ozempic for 2.5 weeks now and I have lost 12 pounds. I don’t eat anything fried or greasy. I watch fat intake because this medicine can make you sick if you have too much fat in what you are eating. It can also make you sick if you overeat. If you eat small to moderate meals with light snacks in between, you will probably not have any problems. If you cannot stay away from fast food and greasy pizza, you will have a problem. I have found that this medicine makes me not as hungry. It takes the edge off. It also keeps me from craving junk. I get full at mealtime, eating less. I drink a lot of water too. I also use an app on my phone to log food, calories, and exercise. I weigh once a week. I hope this helps someone else that is considering this drug."
- Dnw...
- Taken for 6 months to 1 year
- August 30, 2020
For Type 2 Diabetes "I’ve been on Ozempic for 6 months. I had gestational diabetes with both children so I know I have an increased risk of type 2. I had bloodwork done and unsurprisingly my fasting sugar was high, but my A1C was high normal. My doctor prescribed Ozempic and I am currently at 1mg/week. Results: blood sugar in perfect range, lost 20 pounds (15% body weight), loss of sense of taste for tons of foods, alcohol aversion. All in all, I’m far healthier but I do miss enjoying food. I wonder if this is sustainable long term. Time will tell."
- joe...
- November 20, 2020
For Type 2 Diabetes "I first took the 3mg dose for 30 days. I had no side effects, and it is really controlling my appetite. Now I am on 7mg. So far, my weight was 242. I have been on Rybelsus for about 4 months, and my weight now is 215. I'm hoping to lose more. No side effects, feel better, light food craving. I hope to stay on this for 4 more months. Thanks Rybelsus. Joe C."
- Ama...
- Taken for 1 to 6 months
- April 15, 2023
For Weight Loss (Obesity/Overweight) "I never had any weight issues until I turned 60. All the weight gain seemed to go right to my stomach. No matter what I did (including exercise and diet), nothing worked to diminish the belly fat. I started taking Ozempic at 0.25mg/week for 4 injections. I lost 15 pounds on that starter dosage. I increased to 0.5mg the following month and lost another 15 pounds. I will begin the 1mg dose this weekend for the next month. The Ozempic seemed to target that subcutaneous belly fat, which is where I had the greatest weight loss. Except for a mild headache after the first dose and subsequent constipation, there were no other side effects. I took something to relieve constipation. My stomach is now almost as flat as a board, and I don’t look pregnant. I know carrying all that excess subcutaneous fat is very dangerous, and Ozempic melted that fat away. I would recommend keeping yourself very well hydrated and asking your doctor for a prescription to address the constipation. Truly amazing!"
- RNi...
- Taken for 1 to 6 months
- May 4, 2022
For Weight Loss (Obesity/Overweight) "Wegovy does work, problem is... I feel like dirt all day long. I'm fatigued, nauseous, and even the smell of food makes me vomit. My heart races, and I'm quite dizzy. I lost 55 lbs. Do I look good? Yes. Do I feel good? No. I'm down to 153 lbs now. It's time to stop this medication."
Are you taking this medicine?
Your review helps others make informed decisions.More about semaglutide
- Check interactions
- Compare alternatives
- Latest FDA alerts (5)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: GLP-1 Agonists (Incretin Mimetics)
- Breastfeeding
- En español
For Weight Loss (Obesity/Overweight) "This is my 1st injection. I have to say it was much harder to give myself the injection than I thought it would be. I'm not afraid of needles, but for some reason, doing it myself was difficult. But, after my internal battle, I finally did it and it was painless and super easy. Not even a drop of blood. Still too early for side effects, but I will keep everyone posted as I progress. Let our journey begin. Good luck guys! We got this!"