Roflumilast and Loss Of Appetite: What Users Say

• Mom...
• Taken for less than 1 month
• March 27, 2016

Roflumilast for COPD "I have been on Daliresp for over 2 weeks now; I could tell there was much improvement in my breathing. I didn't need to use supplemental oxygen at all. However, yesterday, I couldn't take the nausea, vomiting, tremors, leg aches, headaches, and bathroom trips any longer. I tried taking the medication with and without food, but it didn't seem to make any difference. I'm wondering how long the side effects last? It seems some people don't have side effects at all. I am so disappointed that I won't be able to continue this drug, as I feel that it was helping me with my breathing. But I can't stand the side effects any longer. I have lost 10 lbs in the 2 weeks, I have no appetite whatsoever, and I know that I need the nutrition since prednisone causes bone loss."

• Mom...
• August 21, 2016

Roflumilast for COPD, Maintenance "Started taking Daliresp 3 months ago. Noticed improvement in breathing in 1st week. Then started having nausea and loss of appetite. I also started having other reactions, insomnia, depression, anxiety, panic attacks, bad thoughts about death. Over the last 2 months, it's gotten worse. I didn't know it could be the Daliresp. This morning I woke up at 1 am, couldn't go back to sleep because of thoughts of dying. It's 2 pm, I'm still awake (I can't sleep during the day). Got so bad I went to the ER today. The doctor told me to stop the Daliresp. OK! I never had mental health issues before. I don't have any clue how long it will take to recover from the mental health issues I'm having."

• pau...
• Taken for 6 months to 1 year
• June 7, 2023

For COPD "I started taking roflumilast in August of 2022 after experiencing several severe bouts of exacerbations and bronchitis, one of which required hospitalization. I also use Flovent and albuterol inhalers occasionally, as well as Anoro on a daily basis. I have been using roflumilast for almost a year. I am in my early seventies, retired from being a steelworker, and am a smoker. Pros: roflumilast has practically eliminated my constant bronchitis and reduced the frequency of catching colds and the flu. I have been able to return to nearly normal activities. Cons: I experienced loose bowel movements for the first month, but they eventually subsided. I also lost around twenty pounds. Roflumilast affects my muscle aches, pains, and strength. I sometimes experience occasional severe muscle spasms and cramping. Additionally, I have occasional sleep problems and insomnia, as well as a loss of appetite. There is also some mild depression, which may be related to both age and the medication. These side effects come and go, with good and bad days that can sometimes last for a week. Roflumilast is expensive without insurance. Despite these side effects, the benefits of roflumilast outweigh them. However, there are days when I feel like discontinuing its use. I hope this information helps you make a decision."