Roflumilast topical and Rash: What Users Say

• Jef...
• Taken for 1 to 6 months
• August 30, 2025

For Plaque Psoriasis "Large hives after a few weeks of using Zoryve. After stopping Zoryve, got a rash breakout all over head and face. Monitoring the rash, hoping that it isn't a massive psoriasis outbreak caused by the Zoryve."

• Jef...
• Taken for 1 to 6 months
• August 30, 2025

For Plaque Psoriasis "Large hives after a few weeks of using Zoryve. After stopping Zoryve, got a rash breakout all over head and face. Monitoring the rash, hoping that it isn't a massive psoriasis outbreak caused by the Zoryve."

• Liz...
• Taken for less than 1 month
• October 14, 2024

"I have been suffering with a flaky, painful, itchy head for many years. The flaking was very embarrassing, and recently the pain and itching have interrupted my sleep to the point that I considered taking my life on occasion. My doctor's office gave me a few samples, and after one application, my flaking stopped and the itching subsided, and I was able to sleep again. The cream causes a significant amount of pain, but nothing as bad as the itchy pain I had. With the white plague gone, I have sore, red spots that look like hundreds of bug bites on my scalp. I hope in time the red sores will heal, but all the side effects are much better than the horrible itch and flaking I had before taking Zoryve. My insurance has not approved the prescription for me yet, but I hope they do."