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Roflumilast topical and Headaches: What Users Say

Brand names: Zoryve, Zoryve Foam

Headaches: mentioned by 3 users (5.7%)

Based on user experiences from 53 Roflumilast topical reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

itching 11.3%
diarrhea 5.7%
headaches 5.7%

Reviews for Roflumilast topical

Commonly mentioned side effects
  • Itc...
  • Taken for 1 to 6 months
  • November 15, 2024

For Plaque Psoriasis "I’m happy to see this worked for so many people. I had some success with the foam clearing up scalp psoriasis, but the side effects I experienced weren’t worth the 50% improvement. Constant nausea and headaches after using the foam for 3-4 days. It would take 3 days to feel good again. Tried just using it every third or fourth day… still experienced side effects. So I’m done with this."

4 / 10
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5 Report
  • mar...
  • Taken for 6 months to 1 year
  • July 8, 2024

For Plaque Psoriasis "Gets rid of psoriasis in skin folds, comes back after a few days to a week. I've been using it back and forth with clobetasol, not at the same time, just every few days one and when it comes back, I use the other. It has less side effects than a bunch of other creams I have used, but may give you a headache or make you red for about a day. Pretty much most of these creams available make me red."

7 / 10
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4 Report
  • Wor...
  • Taken for less than 1 month
  • January 31, 2025

For Plaque Psoriasis "I have been dealing with plaque psoriasis on my scalp for over 15 years. After just 4 days, Zoryve foam completely cleared it up, and I was thrilled! On day 9, and for the past week, I have had diarrhea, other GI issues, and some random headaches. Had no idea this was a common side effect of this medication until I researched it online. Very disappointed. Not worth the side effects for me. Cortizone solution has helped in the past, but not nearly as effective as Zoryve. For anyone out there with scalp psoriasis that can't tolerate the side effects, I have found that hair oils help greatly, but it does take time and effort to use."

7 / 10
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2 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.