Ribociclib and Nausea: What Users Say

• Anonymous
• Taken for 1 to 6 months
• March 6, 2023

Ribociclib for Breast Cancer, Metastatic "Have been on Kisqali for two months. In the first week, three tablets every day, but due to side effects of diarrhea, nausea, and fatigue, reduced it to one. Still suffer the above, but not as severely. I do have Fulvestrant injections on a monthly basis. I am hoping with perseverance, side effects will decrease. I had breast cancer twenty-five years ago with metastasis in the last twelve, still not on the organs. I am 83 years old."

• Mum...
• Taken for 2 to 5 years
• March 16, 2021

Ribociclib for Breast Cancer, Metastatic "I have been on Kisqali since September 2018, with no disease progression. Tumor markers in the “normal” range. Side effects: nausea, diarrhea, joint pain, some hair loss in the early stages, the occasional rash or skin sensitivity, fatigue. Having said all of this, I am living my life, working full-time and traveling when possible... life is good!"

• DMa...
• Taken for 2 to 5 years
• November 9, 2020

Ribociclib for Breast Cancer, Metastatic "De novo diagnosis 3/21/18, started 600 mg with 2.5 mg Femara on 3/23/18. Single bone met on right humeral head. Complete remission in July 2019 (after 16 months). 32 months since diagnosis, still clear scans. Some hair thinning at first, along with occasional nausea, blurry vision (mostly in the AM), joint pain, and fatigue. Fatigue is the worst part for me, but my quality of life has not changed at all."

• Kat...
• Taken for 1 to 6 months
• January 29, 2025

For Breast Cancer, Metastatic "At first, Ribociclib caused nausea and vomiting, so I was reluctant to eat and lost about 20 lb in 2 months. Eating 30 minutes beforehand tends to prevent nausea. Another immediate side effect was major fatigue. For the first month, I could barely get out of bed. Sometimes I slept more than 24 hours, only waking every 6 to 10 hours for bathroom breaks, then going back to sleep again. This is very frustrating, but it has improved over time. My depression has worsened - to the point where I think about abandoning Ribociclib because feeling like this for 3/4 of the time is unsustainable - but the medication is very effective. An early blood test showed a significant reduction in tumor markers. This reduction continued in my next blood test. It looks like the treatment is very effective at preventing the tumors from growing. I don't know if any of them have shrunk. A bone scan today should tell us this."