Promethazine for Sedation User Reviews (Page 3)

• MMK...
• December 2, 2019

"I’ve been familiar with promethazine since I was a baby (now 27). Nowadays, I work 1-3 x 12-hour overnight shifts per week and suffer terrible allergies. Before going on Dymista for my hay fever, I would take 10-25 mg of Phenergan each night (or day depending on if I’m working) with a 2 mg SR melatonin, and to be honest, after a week of continuous use, the Phenergan no longer sedates me (down-regulated receptors I think?). However, if I take a break from it, one 10 mg will knock me out in an hour. I sleep deeply and feel groggy the next day. It also helps my anxiety and the nausea I sometimes get with melatonin. However, there are side effects: headaches, fatigue, and because it relaxes the muscles in sleep, mild sleep apnea. I sometimes wake from dreams, gagging/dry retching, or gasping for air. I also suffer from VCD and find I’m more susceptible to attacks when regularly taking Phenergan. I read somewhere that neuroleptic drugs can do this. So now I take it if needed."

• Scr...
• Taken for 2 to 5 years
• March 4, 2015

"I started taking Phenergan to assist with ongoing bad allergies (to dust mites and pollen) and found it very effective for this, as well as guaranteeing me a good night's sleep. I only take a 10 mg dose about 1 hour before bed and no later than 8 pm if I want to wake early for exercise before work. I find if I take it any later, I am lethargic at 5:30 am and take a bit to get going. I have also used the syrup for my young boys as a rare sleep aid. Both my husband (who was prescribed it when he had an allergic reaction to penicillin) and eldest 5-year-old are affected by this antihistamine/sleep aid. It makes them groggy and crabby the next day. My youngest (3-year-old) and I have only positive effects from it."

• Jan...
• Taken for less than 1 month
• October 10, 2020

"Have taken promethazine for 3 nights, have been struggling to sleep for a couple of months now. Has done nothing but give me a slight headache around my temples. If anything, I feel like this has kept me awake."

• Joh...
• Taken for 1 to 6 months
• February 22, 2018

"This drug works for insomnia, but it seems to have a very long half-life, and I feel groggy the next day. Plus, it also gives me depression, which can linger for at least a couple of days after taking it. Depression is a common side effect of antihistamines, especially the strongest anticholinergic ones like Promethazine/Phenergan."

• Sle...
• September 20, 2017

"I was given 25 mg to take nighttime. I found myself waiting hours before it kicks in. Everyone said the next day how well I looked, however, my brain was a bit fuzzy the following day. I shall use this drug to create a sleep routine and then only use it sparingly for emergencies of sleeplessness. I found myself sleeping through the night for the first time in years."

• xxx...
• Taken for 1 to 6 months
• October 17, 2021

Promethazine "I have really bad insomnia. I cannot get to sleep at all. I take 50 mg of Phenergan. And it takes a while to work, like 4 hours, then I fall asleep. I have tried other meds, and they work for a short time, but it is slow to work, so that I lay in bed for at least 4 hours until I fall asleep, but at least it works."

• Mar...
• Taken for 1 to 6 months
• October 7, 2020

"I started taking this a while back to help me sleep. It works in a funny way, doesn’t help me fall asleep, but once I’m asleep - it’s hard to wake up. I take half of a 25 mg pill most times, if I take the full pill, I feel quite drowsy and extremely tired the next day. Maybe it’s because I’m quite small, though. Could quite literally sleep through the day. It surely does work, though."

• KPa...
• Taken for less than 1 month
• May 22, 2020

"Tried promethazine to help with restless legs syndrome at night and think it made it worse. Not sure whether it was me waiting for them to work that made me more agitated or the tablet. Stopped taking them after 3 nights of hardly any sleep."

• Mik...
• Taken for 1 to 6 months
• March 27, 2022

Promethazine "Take 50 mg at night to help me sleep, as it takes away the anxiety. It works a treat. I'm very sedated and calm after 1 hour and can sleep 8 hours. Only downside, I seem to crave sugary foods like chocolate, so I tend to binge (can eat a whole entire packet of biscuits in 10 mins)."

• Tan...
• Taken for 1 to 6 months
• August 28, 2019

"Doctor put me on this promethazine 25 mg 4 times a day for anxiety and to help sleep. I've been on it now for about 2 months. Can’t say it’s worked, but I have gained so much weight, which doesn’t help when suffering with depression as it’s depressing me more. Wouldn’t advise as can’t see how it helps unless you want to gain weight."

• Sam...
• February 16, 2022

"I have used promethazine on and off for years to continue sleeping when I get broken sleep. But I noticed recently that, as well as feeling drugged all day, it leaves me with low mood and irritability too. Just wanted to warn others to be careful, especially if you suffer from depression or are going through a difficult time."

• HDa...
• Taken for less than 1 month
• August 1, 2020

"My physician of three years thought it wise to change from Ambien 10 mg to Phenergan 25 mg for no apparent reason other than he feared Ambien dependency. Well, yes, I have primary insomnia per a sleep study, prescribed Ambien 10 mg, and it has worked well for 19 years. Never needed to increase the dose. The Phenergan/promethazine 12.5 mg took the face off my head. Yes, I slept, but 20 hours later I am still looking for my face, that is, I am hungover with mild cognitive impairment so as not to be able to drive. For some, the side effects aren't worth the sleep. I am one of those. It's back to the Ambien 10 mg or a new doctor."

• sea...
• Taken for 1 to 2 years
• February 4, 2017

"Before you take this for sleep, particularly if you are giving it to children, please read information about withdrawal. I was taking it for Prozac-induced insomnia. Coming off Prozac was easy. Coming off Phenergan is awful. It has been likened to coming off opiates. I am on day two. I am hoping by Monday it will be out of my system and I can restart my life drug-free."

• Fra...
• Taken for 1 to 2 years
• May 23, 2018

"I first used promethazine as 'when required med' when I was inpatient on a psych ward and found that although it worked and helped calm me down, and I stopped hurting myself, it made me extremely drowsy. At the same time, I was on melatonin but found that even 12 mg (more than the highest recommended dose for a child my age) didn't help. I asked my doctor to switch my sleep meds to a mix of both, but he refused as we wouldn't know which one helped. At first, he put me on 25 mg (of promethazine), but after 2 months, I had to have it upped to 50 mg as I had grown too tolerant. I am not on melatonin, and it works a treat with no side effects. ♥"

• Joa...
• July 9, 2019

"I have taken 25 mg promethazine on and off for a few months. It is not over the counter where I live, either. Some nights it works really well. But some nights I toss and turn. I think the 25 mg is not working anymore. May have to up the dose? Did not know it could induce seizures."

• Cor...
• March 16, 2018

"I took 50 mg of the promethazine for sleep, it took at least 2 hours to start working. Once it kicked in, I was beyond tired. I fell asleep in my bed for about an hour and woke up. I got up to head outside for a cigarette, I got dizzy and laid on my living room floor and was out for another good hour. After getting back to bed, I fell asleep for like 5 hours and woke up drenched in sweat, having to change clothes, sheets, etc. Overall, worked good to go to sleep besides the sweating side effects and feeling fuzzy after it's worn off. Most likely would not take again due to the sweats."

• jay...
• Taken for less than 1 month
• April 2, 2021

"My GP had prescribed me promethazine to help combat my chronic insomnia. These pills have done absolutely nothing. I took two x 20 mg pills 1 hour before bed, and it literally did nothing. I had another sleepless night where I woke up about 4-5 times. I carried on taking them for the next 4 days to see if anything changed, but no hope. I’m sorry, but these are useless."

• Mic...
• Taken for 1 to 6 months
• September 3, 2018

"Have severe anxiety and was given this to take in the morning and before bed. It worked well the first 2 nights, sent me straight to sleep, but now it takes hours to fall asleep and I wake during the night many times. Think this is due to my anxiety being severe and needing a stronger dose. No side effects, which is great."

• Stu...
• Taken for less than 1 month
• April 20, 2017

"I was given this stuff when in labor as I had felt nauseated. I think they put it right into my IV. I vomited anyway, but suddenly didn't care much about it. It relaxed me so much that I fell asleep off and on between labor. Since I also have PTSD along with severe insomnia, I wouldn't mind trying it for sleep. It can't be worse than Ambien, where I usually don't know that I ransacked the kitchen and pillaged everything that I could stuff into my mouth. When I wake up in the morning, I find the kitchen in mysterious disorder but have no memory of eating anything, or even getting up. At least with Phenergan I wouldn't have to worry about it."

• Cat...
• Taken for 6 months to 1 year
• February 13, 2020

"Been prescribed promethazine to help sleep for approx 6 months now. Initially, it was my psychiatrist who prescribed it due to the reluctance to prescribe diazepam in case of dependency and addiction. I was put on the maximum dose of 100 mg daily for agitation and to help me sleep (I don't usually have sleep problems, but when I do, they are awful since it's trauma-related night terrors). I took them nearly every day and still couldn't tell you for sure if they helped. I think they may help reduce my agitation slightly, but for sleep, I'm uncertain. That tells me they aren't that effective if I can't even figure out if they made a difference. It's frustrating because I'd hoped this would be a good alternative to diazepam."

• Dud...
• Taken for 1 to 6 months
• April 26, 2018

"I suffered a head injury and had a really hard time being able to sleep afterward. After trying amitriptyline, doxepin, and nortriptyline without success, promethazine/Phenergan was the answer. It wore off a little after a while, and then including 1x ashwagandha 300mg (herbal supplement), it regains a good effect and I have been able to reduce the dose from 25mg to 10mg. It takes about 1 hour to take effect. It is especially good to keep you asleep during the night."

• Nig...
• Taken for less than 1 month
• October 11, 2021

Promethazine "I have recently started taking Phenergan, I take two 50 mg tablets about 20 minutes before sleep. 9 times out of 10, I'm having the most intense nightmares! I've literally just woken up from another. These tablets do work, however, you need to be mindful that nightmares can occur."

• Hud...
• March 8, 2017

"I can't say this drug has no effect, but I'm a chronic insomniac and have been treated for it with Xanax or Klonopin for at least the last 20 years. While mild doses of those drugs have induced sleep, when I've desired more sleep than those 'benzos' have allowed me, I've tried promethazine in varied doses, from 12.5 to 75 mg, and it just doesn't induce sleep like I had hoped. It's very effective for the reduction of nausea, but I'm lucky if it barely makes me drowsy. Sometimes, even the higher doses had no effect at all. Bottom line: This med gets great reviews, so it works for some, but I'm proof that it's not effective for everyone."

• Phe...
• Taken for less than 1 month
• June 11, 2023

Promethazine "Taken to help me sleep, didn't really feel it worked as still awake at 1 am (took it at 8 pm). The next morning, I couldn’t wake up. I was tired all the next day, dry mouth, and was exhausted. Had to stay home as I could barely open my eyes. Won’t be taking it again."

• Gha...
• August 28, 2015

Promethazine "I was prescribed this for my 6-year-old daughter to help her sleep. I've only been using it a couple of nights, but it doesn't seem to be working. I am giving her the 3x5ml dose and giving it to her at 6 pm, and up to now, she is still not going to sleep before 11 pm. Am I not giving her enough or not giving it enough time to work? Advice greatly appreciated! Thanks."