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User Reviews for Promethazine to treat Sedation

Also known as: Phenergan, Promethegan, Phenadoz, Anergan 50, Adgan Antinaus 50

Promethazine has an average rating of 6.0 out of 10 from a total of 91 ratings for the treatment of Sedation. 51% of reviewers reported a positive effect, while 31% reported a negative effect.

Promethazine Rating Summary

6.0/10 average rating

91 ratings from 95 user reviews.

Compare all 23 medications used in the treatment of Sedation.

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Reviews for Promethazine

Kaz · Taken for less than 1 month December 20, 2020

Phenergan (promethazine): “My partner was prescribed 25mg to take each night as he wasn't sleeping. The first night he took one it wiped him out and he was soaking with sweat. I had to help him get undressed and into bed he was that drowsy. The next day he looked drugged up. Then the second night he took another and never woke up, he passed away in his sleep. I thought he was just sleeping until I found him. The post mortem came back un-ascertained and I have been told it will take anywhere between 6-8mnths to get an answer however this is the only new medication he had taken. His other meds he took regularly so I blame this. Please be careful with this drug.”

1 / 10
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Mary August 13, 2020

Phenergan (promethazine): “Please be careful with these. About 3 years ago I took some to get a few hours sleep. I had to ask the Pharmacist for them as they were kept behind the counter. I got the 25mg’s and had no idea how strong they were. I’m embarrassed and still feel humiliated with what happened. I took 2 at first, I honestly thought they would just give me a few hours sleep and nothing else. I was hallucinating!! I won’t go into great details but I thought my family were in the house with me, they weren’t. My family and neighbour told me some of the things I did. They ended up calling an ambulance. I wrote to the company and also did a long internet search which I discovered that one rare side effect was in fact hallucinating. Please be careful with them. A big lesson learnt, always take as prescribed.”

1 / 10
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JohnSmith · Taken for 1 to 2 years October 29, 2020

Phenergan (promethazine): “I took 25mg Phenergan to help me sleep. It worked! I've been taking it for almost 2 years but only recently realized, when I stopped taking it, that it was causing me to have a low mood and a REALLY dry mouth to the point where I needed a drink with me at every meeting because it would affect my speech. When I stopped taking it, I woke up 4-5 times in the night, which is normal given I've got small children, but woke in the morning feeling a lot more clear-headed, less headaches and didn't have the need to guzzle glasses of water! Pharmacists only ever warned of drowsiness but not these side effects so wanted to share them with everyone! This medicine will get you to sleep, but it comes with a significant cost!”

5 / 10
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Sal · Taken for 2 to 5 years September 13, 2020

Phenergan (promethazine): “I suffer PMS and insomnia. I tried all types of herbs and supplement sleep aids even Melatonin with worked for me for a couple of nights but d be back to the same thing waking up at 3am or not sleeping more than 3 hours a night. My Gp told me about Phenergan. I took the 25mg 2 hours before bed for 5 nights and it 100% worked . Able to carry over month by month with great sleep. Wonder drug thank you Phenergan my friend”

10 / 10
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Jo · Taken for less than 1 month August 2, 2019

Phenergan (promethazine): “This stuff is garbage for sleep. My doctor put me on this & took me off Zolpidem which worked great. Why screw with what works? Promethazine may work for people with mild sleeping issues but for those of us with severe insomnia it's like taking a skittle candy. Doesn't do a thing!”

1 / 10
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Clack69 June 7, 2020

“I’ve been prescribed Benzos for sleep whenever I’m too anxious, on and off since I was about 20. I wanted to stop using benzos and switch to something weaker and non prescription. I took 2 25mg promethazine tablet first night. Woke up 2 hours later wheezing and felt like my throat was closed up. I was so groggy I couldn’t get out of bed. I don’t remember falling asleep again but I woke up late the next morning. My anxiety that day was worse than the anxiety I felt before sleep. I tried promethazine again a week later, this time only 1 25mg tablet. Slept through the night, woke up groggy and felt that intense feeling of anxiousness and paranoia again. This drug should not be sold over the counter! This drug has worse side effects than benzos! Awful drug! I will never touch it again! If you have anxiety, DO NOT take this drug! It is not safer than prescription anxiety medication and I would consider it the worst drug I’ve tried.”

2 / 10
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scg123 · Taken for 1 to 6 months June 12, 2021

Phenergan (promethazine): “I don't know if I class myself as an insomniac but I usually wake up a load of times in the night which disturbs my sleep and makes me tired in the day so I decided to try Phenergan. This medication should really be taken just before you go to bed, I wouldn't recommend taking it while you're watching TV or anything because in my experience, you have to be trying to fall asleep for this to work. Even then, it's a horrible drug. 25mg is too little and I still wake up in the night a lot, 50mg is way too much and I'm pretty sure my throat closed up for a second in the middle of the night because I woke up gagging and I don't suffer from sleep apnoea so that was weird. Either way, any dosage of this stuff causes terrible daytime drowsiness the next day, I'm not sure if that's down to the half life of the medication or whether it is purely because it gives you really poor quality sleep.”

1 / 10
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Frequently asked questions

Cmt85 March 28, 2021

“So I've been on this tablets for 4 years now and still on 100mg that I was prescribed. I suffer severely with my sleep as I suffer with bipolar and schizophrenia and these tablets work wonders for me I get a straight 6 hrs sleep which is amazing. I used to be on zopliclone but found myself waking 2 or 3 times a night in my 6 hours sleep this isnt a good scenario for me. I absolutely praise this medication and who knows where I would be without it if here at all. It's worth giving it a try but everyone is different and have different side effects.”

10 / 10
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Anonymous May 16, 2009

Phenergan (promethazine): “I've used Phenergan, which is sold over the counter, as a sleeping aid for about one year now. Taken one hour before bedtime, it rarely fails to put me to sleep. The wondrous thing is that I have kept the same dose, and there are no withdrawal symptoms, if you stop using the drug for a week or two. Definitely the best substitute for any prescription sleep aid, that I've ever tried. Highly recommended as a sleep aid.”

9 / 10
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Marts February 8, 2021

“Experience on promethazine 25mg: slept undisturbed for a good 10 hours, found it super difficult to wake up, had to battle with my body to open my eyes and all I wanted to do was carry on sleeping. Kept on falling back asleep and waking up. Felt sedated and tired all day afterwards. Experience on 12.5mg (approx) splitting the pill in half: Slept for a long time, but still had negative side effects when waking up, I was very angry at my partner who tired to wake me up as I just wanted to carry on sleeping. Felt tired during the day also, but not as bad. I find that my optimal dose is about 1/3 of the tablet - it helps me sleep and the side effects of tiredness aren’t as bad in the morning. I do still experience agitation when woken up by someone else and would rather carry on sleeping but it isn’t as severe and usually after 20 mins or so I’m fully awake. The sedation/tiredness feeling during the day isn’t as prominent.”

8 / 10
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Walsh02 · Taken for 1 to 2 years May 10, 2019

“I’ve given a review of 8/10, not because this medication isn’t perfect at addressing insomnia, because it is but for the fact it’s just another crutch. I had severe insomnia for approx 2 year, having always been a troubled sleeper. I would be awake all night, on the verge of tears, having to cancel my next day’s clients. It was hideous. This worked like a dream, didn’t make me feel strange or cause a racing heart. If I have issues again, this will be my go to. I just want to share my ‘cure’....binaural beats - a type of music or sounds which really works for getting me to sleep. I listen to them throughout the night, set on a low volume and for the first time, I’m falling asleep almost as soon as my head hits the pillow and waking up bright and early, full of beans. I was also informed that my circadian rhythm was messed up, which is why my sleep signals weren’t working. As well as the binuaral beats, i also limit myself to coffee only in the morning and have tried to drastically cut down on alcohol.”

8 / 10
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RickRicky August 30, 2016

“I was having terrible sleep for past 5 days waking up between 1-3am with intense cramping. My doctor gave me some pills, I have never had a sleeping pill before. I slept non stop, In fact I had some trippy dream that I flew a spaceship to Dubai and landed on a skyscraper.....I now know what Dibai will look like in 50 years....Highly recommend”

10 / 10
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freddy22 · Taken for less than 1 month May 19, 2019

“I was given promethazine for nausea related to anxiety. When anxiety gets bad I can not eat, even the thought or smell of food can make me want to vomit. Sometimes I even get so worked up I do vomit from my anxiety. Promethazine at 12.5mg has helped my nausea tremendously. Also I did notice it helps my anxiety as well! Only down side for me was morning grogginess if I took it at night and light sensitivity during the day. I use this as a substitute for Ativan. It is great and works for two things I now have no nausea, lower anxiety, give it a shot.”

9 / 10
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Anonymous September 19, 2010

Phenergan (promethazine): “Although I have fairly high blood pressure - for which I take medication, and use asthma inhalers to prevent asthma, I have found Phenergan to be absolutely marvelous for insomnia - I have an overactive mind! I find it's best to take it about four hours before I go to bed - then it knocks me out for the night. Sometimes I still feel a bit drowsy in the mornings and have discovered I only need the lowest dose to get a good night's sleep. I only take it the night following a sleepless night. Hope this is helpful.”

10 / 10
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Shelly · Taken for 6 months to 1 year February 4, 2021

Phenergan (promethazine): “I took two to get some sleep as I suffer from insomnia and we had a family gathering the following day. Still hadn't fallen asleep by 5am so took another one. Family turned up, I don't remember. I thought there were worms crawling in my carpet, I was talking to a mop which I thought was a person, thought I saw millions of baby spiders on the walls. I lost track of about 36 hours and was hallucinating the entire time! After doing an internet search, I found out they can cause hallucinations! They should have it on the box. I wrote to the company but never heard back. I was so embarrassed and felt humiliated in front of my family. At one stage they phoned for an ambulance. PLEASE be careful with them.”

1 / 10
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Kelly · Taken for 1 to 6 months November 28, 2018

Phenergan (promethazine): “Has anyone had weight gain with Phenergen 25mg? I've put on 5 kilos quickly since using this & another drug, Valdoxen. Valdoxen helps which your melatonin receptors, is also an antidepressant, & says you do not put weight on. Not sure which one it is! Phenergen does say it can cause weight gain, esp in females, but they are not sure why. Though they state it's thought it can make you hungry thus you eat more. This isn't the case for me. I've been eating & exercising normally so something is going on. It's fabulous for sleep though, I finally get a great sleep. Confused!!”

8 / 10
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Anonymous October 2, 2019

“I‘m getting prescribed promethazine for insomnia which is caused by a bad Social anxiety (I get the feeling someone is watching me I‘m sleeping, and generally when I leave my house I get really anxious. Which sometimes leads to me not leaving my house for month other than when I have to work.. etc.) I‘m taking 25-50mg half an hour before I go to bed. It really does help me with my sleep as well which kinda lowers the anxiety that also was caused by my lack of sleep, but it doesn‘t completely kill the anxiety. Just a tip from me if you want to get rid of your anxiety stop taking stuff like benzos or so and quit doing drugs if you currently do any. Start meditating it really can calm you down and makes you get along with yourself! I didn‘t believe it, till I tried it! Promethazine is good for sleeping and that it. Last thing I wanna say: it sometimes doesn‘t help my insomnia as well, that really rarely tho! I‘ve been on this medicament for almost three months now!”

10 / 10
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Shygirl84 December 8, 2018

Phenergan (promethazine): “I took 3x 25mg Phenergan too help me sleep the next morning I woke up covered in bumps & bruises apparently I had a grand Mal seizure through the night I haven't had a fit in 9 yrs. The chemist failed to tell me this drug can bring on seizures. Just want other people to know about this as I was unaware... Thanks”

1 / 10
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Jamwock · Taken for 5 to 10 years February 19, 2015

Phenergan (promethazine): “I have no problem falling asleep, but wake in the night and sometimes cannot fall back to sleep. I take one half tablet 12.5 mg of Phenergen and even if my sleep is disturbed I fall back to sleep easily, and wake up refreshed.”

10 / 10
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Equalizer · Taken for 1 to 6 months May 22, 2020

“I was prescribed promethazine for insomnia due to tinnitus. I took 25mg doses before bed when needed. Within about 30 minutes, I felt exceptionally drowsy and in a very relaxed state. Any anxiety I was experiencing was gone. I slept solidly for about 10 hours and then would wake up feeling pretty drowsy. I also cautiously took it when I had a chest infection and an asthma flare up. I got a great night's sleep and woke up feeling far less wheezy and with far less sputum. After six weeks of taking it nightly, it took a bit longer to make me sleepy and I woke up after less time. Then, suddenly, I found that taking the promethazine gave me extreme bouts of sleep apnoea. I repeatedly woke chocking and breathless. I immediately stopped taking the promethazine. I am now two days into withdrawal, waking up in the middle of the night feeling sweaty and finding it hard to go back to sleep. Overall, the drug really helped me but the apnoea and the withdrawal I had was a bit unpleasant.”

8 / 10
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another long-time user July 23, 2013

“I'm 73 years old now and started taking Phenergan a long, long time ago. For the last 35 years I've taken a little more than 1/2 of a 25 mg tablet just about every night, about 3-4 hours before I want to go to sleep. Although I wake up about 3 times/night, I fall back to sleep easily and sleep for 8 to 9 hours. It is very "drying" but I consider this worth the good sleep. Often I combine it with 0.5 mg melatonin.”

10 / 10
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trainman December 16, 2008

Phenergan (promethazine): “This medicine helped sedate me when I was having back pain. I had two herniated discs and it calmed me down before and after the surgeries. It is not habit forming and was a plus with all the other medicines I was on.”

9 / 10
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Kate111 October 8, 2015

“I take phernergan to help me sleep when I am run down or am needing that extra bit of sleep. It always knocks me out within an hour and I sleep like a baby! I struggle to wake up if I take a higher dosage but I wake up feeling refreshed and like I have slept for years! I recommend it to everyone who has trouble sleeping! I have also used it for hay fever but never really saw any remarkable changed in my allergy.”

10 / 10
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Sleepeasy April 4, 2020

“I have used Phenergan on and off for a few years for insomnia. They work extremely well. I take just 12 mg and that gives me six hours. If I take 1 25mg I am sleepy all morning and not terribly motivated to do much. However the down side is they make me terribly hungry. I am basically good at controlling my weight and appetite but on these l lose that control and seem to snack all day.”

8 / 10
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Gina · Taken for 1 to 6 months February 13, 2019

Phenergan (promethazine): “I only take 6mg (1/4 of 25mg tablet) at night before I have to work next day i.e Sun to Thurs night. The first time I took a whole pill, never again as it knocked me out but next morning had to stay home as I was so drowsy! I prefer this to taking Lorazepam.”

9 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.

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