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Pregabalin for Generalized Anxiety Disorder User Reviews

Brand names: Lyrica, Lyrica CR

Pregabalin has an average rating of 8.3 out of 10 from a total of 358 reviews for the off-label treatment of Generalized Anxiety Disorder. 79% of reviewers reported a positive experience, while 9% reported a negative experience.

Pregabalin rating summary

8.3/10 average rating

358 ratings from 375 user reviews.

Compare all 14 medications used in the treatment of Generalized Anxiety Disorder.

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19%
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13%
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3%
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Reviews for Pregabalin

  • mbolo...
  • Taken for 1 to 6 months
  • December 22, 2023

"I have been struggling with anxiety and depression my entire life. Over the years, I have done a lot of self-medicating. I finally reached out for help and was prescribed Klonopin. I also tried a number of SSRIs, Buspar, and Wellbutrin. The SSRIs left me feeling entirely flat. Buspar left me borderline suicidal, and Wellbutrin made me feel crazy. After 9 months, I stopped taking Klonopin. At this point, my mental health was the worst it has ever been. I was convinced I was going insane. I had constant visual disturbances, panic attacks, depersonalization, and derealization. I was also horribly depressed and frustrated. I felt like doctors had only made things worse. Eventually, I found a new doctor, and they put me on Pregabalin. Two days in, I caught my reflection in the mirror. I saw a man who was at ease. He was smiling. It was the first time I had seen that guy in years. I honestly believe that this drug saved my life. It has allowed me to live again. Anxiety, GONE. Depression, GONE!"

10 / 10
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109 Report
  • nick...
  • Taken for less than 1 month
  • November 10, 2019

"Xanax is perfect for panic attacks. Klonopin is perfect for eliminating anxiety for your daily activities. Pregabalin is perfect for knocking your entire anxiety out of the park. Physical, mental, everything. Anxiety DESTRUCTION."

9 / 10
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524 Report
  • Tempest
  • Taken for 2 to 5 years
  • May 14, 2021

"I have been on this on and off for 4 years now. Originally 300mg daily for 4 months. Gradually dropping down to 100mg a day. I now take as and when I feel a wobble coming on. It has been a life changer for me. It helps calm me down within an hour if anxiety gets bad. My GP suggested using as and when I needed it, and I have had no problem with that scenario. I think my body is used to it. I was originally put on antidepressants which sent me loopy. Then a psychiatrist suggested pregabalin. It really helps with sleep and helps me switch off. Getting off this tablet was no problem as it can be dropped in doses of 25mg. I had no problems with it at all. If you have a chance to take it, please give it a go. It works really quickly and can be a game changer."

10 / 10
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349 Report

Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • November 29, 2019

"I have struggled for years with depression and anxiety. I also suffer from nerve pain. I was prescribed gabapentin for this. After having a major meltdown and going to the out-of-hours doctor and sitting in his office crying and asking him to 'please help me!', he changed my medication to pregabalin. This not only would sort my nerve pain but also help my anxiety, and oh my god has it! I can't ever remember feeling this good! Anxiety, what anxiety! It's so fast-working too, I was amazed. I wish I had been prescribed this years ago. As for side effects, I have put on weight but I'm so much happier, I don't care! And a dry mouth, I can live with that. I am in the UK."

10 / 10
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418 Report
  • Muddy
  • Taken for less than 1 month
  • August 21, 2020

"I had experienced some major stressors over the last 2-3 months. My anxiety level was starting to get out of control, and I was in a manic-like state. I asked the emergency clinic for 75mg pregabalin 2x/day. I picked up the prescription the next morning, took one 75 mg pill, and slept for about 4 hours. When I woke up, my anxiety was GONE. My brain had been a constant buzz for over a month, and pregabalin turned off the switch. Physicians need to know about the use of pregabalin for anxiety."

9 / 10
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308 Report

Are you taking this medicine?

  • Darren
  • May 22, 2020

"I have suffered with anxiety and depression since I was a child. I'm now 47 and have tried endless different types of other medicines, and now Pregabalin has saved my life. I take 600mg a day. It calms me, gives me confidence, and energy. It's a wonder drug as far as I'm concerned."

10 / 10
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299 Report
  • Johnny
  • Taken for less than 1 month
  • September 15, 2019

"Been on pregabalin for 2 weeks. Only 50mg twice a day. I suffer from social anxiety. Always in fight or flight mode when around people. As a result, this causes me to feel very low. However, my experience so far has been very positive. I am feeling so much more relaxed, and my anxiety is down to about a 2 when in social situations. My sleep is also better. I do get red eyes in the morning while on this med. Small price of such great relief. Life just seems so much easier, and I am so much more relaxed. It is early days, and I just hope this continues to work for me. Also never wrote up on any site like this. I have tried a lot of the SSRIs. But no good. Best of luck to all trying this med. I share your pain if you are reading these review sites."

9 / 10
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328 Report

More FAQ

  • Anonymous
  • Taken for 2 to 5 years
  • February 14, 2020

"Been taking now for over 2 years and it’s honestly been a wonder drug - as I’ve said in previous reviews. I’ve cut down from 300mg to 100mg and it was actually fine, although now my life circumstances have changed and I’m going through a transition, I may take higher doses when needed and this is fine. I’ve found taking a spiritual path really helpful but equally, an anxiety disorder is something that can be life long and genuinely neurological and genetic. You need to treat the core reasons of why you are anxious but equally medication is sometimes necessary. This medication has always kept me feeling safe and stops me from extreme panic. Anxiety just has no place in my life and this stuff truly keeps it at bay. Weight gain sucks but I’d rather weigh a bit more and have peace of mind."

10 / 10
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293 Report
  • Renn
  • Taken for less than 1 month
  • February 2, 2020

"I've had GAD since I can remember and it's ruled my life, but since I've been taking Pregabalin, it's totally knocked it on the head! Now I'm the happiest person on earth! I've been taking every type of benzo that's out there, but NOTHING has touched it like this medication... Some of the side effects are still there, but the drunk-kind-of-walking has stopped. I'd much rather have the side effects than have this crippling anxiety that turned me into a hermit for years. I'm taking 75 in the morning and 75 in the evening. I haven't been on it long enough for any kind of weight gain, but in saying that, I'm quite thin and tall, so I wouldn't mind some weight! Wish I found these meds years ago! YEY!"

9 / 10
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280 Report
  • Tonyg...
  • Taken for less than 1 month
  • November 2, 2019

"Pregabalin is the best thing that’s ever happened to me. I’m a combat vet - I suffer from PTSD, GAD, & Depression - I’ve tried so many different medications and currently on a combo of Prozac and Pregabalin (PG). The antidepressant works wonders and the PG makes life liveable. Like I actually want to go do things and be with people now that I’m not terrified every day and in fight or flight literally all the time. My feet would get cold - my hands would start to sweat - and my heart would pound in my throat - NO MORE. 150 MGs does the trick and I’ll gladly stay there as long as possible. I used to abuse benzodiazepines because I didn’t understand what was happening in my body and what stress can do to a mind - now I know. Thank God for PG."

10 / 10
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271 Report
  • franc...
  • July 31, 2013

Lyrica (pregabalin) "Pregabalin for me was miraculous. On the first dose (75mg three times a day), my anxiety was reversed. I really thought this was too good to be true. I have tried Prozac and lorazepam at different times of my life. But as is commonly known, after the fourth or fifth trial of SSRIs, they 'peter out' and actually become counterproductive, even in some cases causing serotonin syndrome. But about two years ago, I was in a very stressful marriage break-up and was taking benzodiazepines to keep the lid on the anxiety, with little effect. The GP respected my wish to try Lyrica. I was and still am, after two years, astounded by this transformation. I feel like I always felt I should feel. A cessation of anxiety and a sense of well-being pervades."

10 / 10
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446 Report
  • realman
  • November 6, 2015

"Lyrica is the best thing that happened to me in 15 years. I have tried nearly every medication on the planet for my severe anxiety and untreatable depression: SSRIs, SNRIs, TCAs, MAOIs, Benzos, Ketamine infusions, ECT, CBT and many illegal substances with zero help. I'm on 150mg twice a day and it has literally made me a new human. I feel like when I was a teenager, before the depression and anxiety started to ruin my life. I expected it to ease my anxiety somewhat, but what I didn't expect is that it completely killed it along with the treatment-resistant depression. I have no side effects! Thank you, science!"

10 / 10
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336 Report
  • Silve...
  • Taken for 1 to 6 months
  • January 26, 2021

"I've been on 20mg escitalopram (Lexapro) for 3 months with only a partial response to my GAD/SAD, so my psychiatrist decided to augment my therapy with pregabalin (Lyrica) split into 2 doses of 75mg (morning and evening). This turned out to be the winning combination that completely alleviated all of my symptoms. The only side effects I experienced on pregabalin were increased sleepiness at the very beginning of treatment, which quickly went away. It's a miracle pill for anxiety in my opinion, and I hope this helps others!"

10 / 10
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159 Report
  • Char...
  • Taken for less than 1 month
  • March 12, 2014

"Lyrica has been incredible for my anxiety! Within just a couple days, I was running errands without needing to have someone with me due to anxiety. I was doing chores, which I often delayed without a second thought, and I was enjoying my life and time with my children. I was prescribed pregabalin for fibromyalgia pain, and I can't say I've noticed a difference with pain, but it has done everything for my anxiety! I am way less irritable and moody and feel like I can actually enjoy living a happy and complete life for once without worry, fear, or nervousness. I went from being a procrastinating homebody to a normal-feeling, confident person! My side effects have been blurred vision, sometimes feeling a little sleepy, and dizziness. It's 100% worth trying!"

10 / 10
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344 Report
  • Barnzy
  • Taken for 5 to 10 years
  • May 31, 2021

"I have been on this medication for about 5 years now, before I was on it I was a mess, I couldn't even go outside because I didn't want anyone to see me in case they try to chat - I can't do convos with people very well, I am also autistic and epileptic & GAD which made my life a mess but pregabalin annihilates anxiety and also helps my epilepsy, This is the best medication you will ever get I advise you all try it if your doctor allows it as it really has the potential to change your life around. I can go outside now without worrying about anything. 10/10"

10 / 10
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125 Report
  • Meika
  • Taken for less than 1 month
  • February 2, 2020

"I've had crippling GAD since I was a kid, and since being on Pregabalin, I'm now able to say see ya later to the anxiety that's stopped me from living. As I've been a hermit for over 10 years! I've tried every benzo there is, but after only a very short time, I've been so happy to find this medication! I'm taking 150mg per day, and the side effects are still going on, but I'm not going to stop these meds for relief is totally amazing! They should go, as I've read from other people, but I'm willing to put up with them, for this is like a miracle or something! I wish I found this years ago. Living at last, not just existing! Take care, people!"

9 / 10
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164 Report
  • Chris...
  • Taken for 5 to 10 years
  • January 26, 2024

"I have been on this medication for about 8-9 years now. I have been diagnosed (at 18 years old, 31 now) with Autism, GAD, and Epilepsy. I started on a very low dose (100mg per day) and now on 200mg three times a day. It controls my seizures along with sodium valproate, and what it does for anxiety is incredible. It's like an omnipotent medication. All these people saying about withdrawals, yes, you can get withdrawal symptoms if you stop cold turkey, but not as bad as Benzodiazepines or illicit drugs. Keep to your prescribed dose, and I think this medication will change your life."

10 / 10
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23 Report
  • laya
  • Taken for less than 1 month
  • January 1, 2024

"For the first time in my life, I feel relaxed, happy, and content. Less irritability, more stability, and fewer emotional outbursts, if any. I'm autistic, have major depression, and extremely bad anxiety. I have had insomnia all my adult life. I've tried every antidepressant, sedative like diazepam, and nothing has helped. I've experienced lots of horrendous side effects. I do take duloxetine as well. But pregabalin has changed my life. I no longer have suicidal thoughts and I feel so relaxed like never before. I sleep much better and don't have night terrors."

10 / 10
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25 Report
  • Mike...
  • Taken for 10 years or more
  • December 25, 2021

"Hi Been on this drug for 10 years+ and I gotta say that’s it has a marvellous effect on me. I suffer GAD and child trauma. My anxiety hits me as soon as I wake so I hit it back with 150mgs which works whilst I’m drinking my tea etc. I then top it up midday with another 75mg and my day is just normal. I know all the talk of getting to the “root” cause etc etc but just to get relief from crippling anxiety. It’ll do for me!!!"

10 / 10
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96 Report
  • Miracle...
  • Taken for less than 1 month
  • August 15, 2023

"After coming off 25 years of Valium, I had the most horrible anxiety and insomnia which I never had before. The Valium was prescribed for muscle spasms. Anyway, after stopping Valium, I had crippling anxiety around the clock and sleeping... forget it. I'd wake up at 1, 2, 3, 4, etc., every night. There I sat, so very exhausted yet wired with anxiety. Went to a shrink who prescribed the usual SSRIs which did nothing but give me horrible side effects. Then I asked my pain management doctor to prescribe me Lyrica after having read that on top of pain, it is good for both anxiety and insomnia. I have only been on 50mg three times a day for five days, but I can honestly say my anxiety is gone, and I've slept seven to eight straight hours a night since starting it with zero side effects. I don't care if I have to take this for the rest of my life. If so, I will. It is a miracle drug."

10 / 10
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41 Report
  • thund...
  • December 20, 2019

"This is an amazing substance that might as well have come from outer space. I have been prescribed all sorts of psychoactive drugs over the years that started with a bad LSD experience. Finally, the doctors have got it right. Definitely a 10/10!"

10 / 10
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147 Report
  • ndr_mlt
  • June 2, 2020

"This stuff Pregabalin is amazing. At the dosage of 450mg it increases mood, empathy and has an uplifting effect like no other thing on this earth (on the legal side). It helps too with my social anxiety. I'm agree with my doc to take it in the bad days so to not dissipate the positive effects. I hope my tolerance will not increase. P.S I don't recommend in any way a recreational use. Like with any other substance there are horror story on the net. Stay safe and talk with your doctor."

10 / 10
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134 Report
  • Sircrag
  • Taken for 1 to 2 years
  • May 1, 2014

"I have suffered with severe anxiety and depression for years. I tried 6 different antidepressants as well as benzodiazepines, and all did nothing for me or any help. Eventually, I was put on Pregabalin by a Psychiatrist, and it was very helpful, almost from day one. We increased my dose until I take the maximum of 300mg twice a day. At this dose, my anxiety has been pretty much eliminated. I am happy and now an active person. However, a word of warning to anybody taking this medicine for a long time: DO NOT allow yourself to suddenly withdraw from it. I recently had to go a week without it, and it was a living hell for me. Withdrawal symptoms for me were as follows: severe anxiety and depression, suicidal ideation, inability to sleep, nausea, and vomiting."

10 / 10
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268 Report
  • Pete
  • Taken for 1 to 6 months
  • April 17, 2022

"Diagnosed with Complex PTSD, Borderline Personality order, Generalised Anxiety Disorder. Had anxiety most of my life, which has been particularly bad last three years. Recently spend 5 weeks in a psychiatric hospital due to severe anxiety (body shaking - planning the end of my life prior to admission to hospital). Consultant on the Ward put me on 300 mg Pregabilin /daily. It has made a major difference to my anxiety levels - I am much calmer. People say I am much more present and my thought no longer go all over the place - ten thoughts at once! I have been taking Pregabilin for about 9 weeks now. I feel like my old self - my sense of humour has come back, am no longer suicidal and feel optimisitic about the future. I see a psychiatric nurse weekly and tell her how I really feel - which helps. The relief from anxiety is wonderful - as I have a full time job (social worker)."

9 / 10
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83 Report
  • AKM
  • Taken for 1 to 2 years
  • October 18, 2019

"I’ve been on a million medications for anxiety/depression (usually multiple at a time). Pregabalin drug was suggested when I was studying abroad in England (I’m from Canada), and it’s the one medication that’s stood the test of time. I even was able to get off all my other medications!"

10 / 10
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149 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.