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Adipex-P and Insomnia: What Users Say

Insomnia: mentioned by 45 users (7.4%)

Based on user experiences from 609 Adipex-P reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dry mouth 27.3%
headaches 7.7%
insomnia 7.4%
tremors 4.3%
increased heart rate 4.1%
loss of appetite 3.4%
anxiety 3.0%
constipation 2.8%
nausea 2.6%
dizziness 2.5%

Reviews for Adipex-P

Commonly mentioned side effects
  • She...
  • May 20, 2019

For Weight Loss (Obesity/Overweight) "It does work. You have to work with Adipex though. You have to stay hydrated. You have to eat at least 1000 calories if not 1200 daily. You have to exercise a little. Even if it is just walking. You need to also take it very early and take it around the same time each day, like 6 am or 7 am. I would not go past 8 am if you are sensitive to medications. Otherwise, you will be up all night long, ready to run around. You also need to change the foods you eat. We are fat because of what we eat. This is not a magic pill that will melt your fat away. You need to correct yourself for it to really help you on your weight loss journey. This is all common sense. It raises your heart rate up (it's almost like speed). That is what gives you the energy that we are all lacking. For me, Adipex is a fantastic appetite suppressant. Good luck."

8 / 10
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  • Kri...
  • Taken for 6 months to 1 year
  • July 19, 2014

For Weight Loss (Obesity/Overweight) "I started off on the highest mg, which is 37.5, and it has worked very well for me. In my first month, I had lost 26 lbs, and in 6 months, I lost a total of 90 lbs. I DID NOT EAT HEALTHY NOR DID I EXERCISE. I took a break from it a couple of months back because it's not safe to take it for an extended period of time due to the fact that it takes a toll on your liver. I just got back on it again yesterday. It will cause you to have DRY MOUTH, CONSTIPATION, URGES TO DRINK LOTS OF WATER, ENERGY, ABILITY TO STAY FOCUSED, INSOMNIA, FAST HEART RATE, MOOD SWINGS, NAUSEA, AND EASES BODY PAIN. I have a heart murmur and panic attacks, so after taking this medication, I notice it gets harder for me to breathe as the day goes by."

9 / 10
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331 Report
  • Blo...
  • January 28, 2020

For Weight Loss (Obesity/Overweight) "I have been on Adipex for two weeks. My doctor suggested it to help me lose some weight. I was 200 pounds at the start. I am now 194 lbs after 2 weeks. I take a half pill a day. I work at a desk all day and would have issues with snacking all afternoon. Now I don't. I force myself to eat some fruit every afternoon or a protein shake. I can't eat a full meal because I feel fuller faster. I have more energy. I have had dry mouth, but drinking water is a big help with that, and I drink a lot more water. I do have some heart racing at times, but the more water I drink, the better that is, which is good because it did throw me into a few panic attacks. No headaches. I did get insomnia the first two nights, but I switched to taking the pill at 10 am instead of noon and that stopped. I started exercising so hope to see more weight drop off. My goal weight is 145, but I am only taking this until my bottle is gone."

8 / 10
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Frequently asked questions

  • big...
  • Taken for less than 1 month
  • November 12, 2013

For Weight Loss (Obesity/Overweight) "I just started Adipex 3 days ago. I'm having some insomnia and terrible dry mouth. But I also have mad energy and a little appetite. Adipex is amazing! Compared to having no energy, terrible depression, and feeling like there was no hope, I feel great! Hopefully, this continues - don't give up, there is help out there!"

10 / 10
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163 Report
  • Que...
  • Taken for less than 1 month
  • December 21, 2019

For Weight Loss (Obesity/Overweight) "Started Adipex late October, now it is in the middle of December. I have lost 20 pounds. The pill literally cut my appetite, and I drank water. No sweets, breads. I really didn’t exercise, but housework, working, and being a full-time Mom and Wife. I guess you can say that’s where it came from. The only side effects I had were dry mouth and insomnia, nothing too bad. Oh, and yes, I could have lost more weight, but I skipped some days taking the pill."

10 / 10
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  • WOR...
  • April 30, 2013

For Weight Loss (Obesity/Overweight) "Started my first dose Thursday 4/25 weighing 222 lbs. Today 4/30 I am at 209.5. That's a 12.5 lb loss in 6 days! Can't wait to see where I'm at on day 30! Only side effect I had was trouble sleeping. Started taking Unisom and problem solved. I never got dry mouth because I drink close to a gallon of water a day. So far so good so I'm going to keep on keeping on!"

10 / 10
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95 Report
  • Anonymous
  • September 15, 2008

For Weight Loss (Obesity/Overweight) "I started using Adipex in March 08, weighing in at 332 lbs. As of September 08, I am now 284 lbs. I lost 48 lbs in 6 months. At first, I had a little trouble going to sleep, but that went away after a couple of weeks. I think that the pill is totally worth it. Now I have really picked up my exercise routine, and I am very cautious about what I eat. I have very little starch at all. My exercise consists of 3-4 miles on the treadmill at 6-7 mph and then 30-45 minutes in a sauna every day. I would suggest taking the pill for 2-3 weeks, then laying off for a week. This is what has worked for me."

9 / 10
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126 Report
  • Anonymous
  • January 25, 2010

For Weight Loss (Obesity/Overweight) "I started taking Adipex on November 17, 2009. It is now January 25, 2010. I have to admit when I first started taking Adipex, I felt like I was on straight speed. I couldn't sleep, eat, or concentrate. I still have bad mood swings and get upset very easily. I have no problem sleeping, that wore off the 3rd week. I tend to get hungry later in the afternoon. I was taking a half of a pill the first month. I take one pill a day now and do great, except for my mood swings. My starting weight was 165 lbs. I now weigh 138 lbs. That's a weight loss of 27 lbs. I still have 8 lbs to go. I exercise 5 days a week on the treadmill for 30 minutes each time. If you are really wanting to lose weight and can overlook the side effects, this is the pill! Good Luck!"

10 / 10
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102 Report
  • sar...
  • Taken for less than 1 month
  • June 5, 2015

For Weight Loss (Obesity/Overweight) "I went to a weight loss clinic on Tuesday, June 2nd. I have been battling my weight for years (ever since I had 4 kiddos). I'm 5'5, and my starting weight was 184.4 lbs. I started the prescription the same day that I had it filled, and as of today, Friday, June 5th, I am down to 177 lbs! This is absolutely unreal! 7 lbs in 3 days! I have had slight insomnia, constipation, and crazy dry mouth, all of which are easily solved. A little melatonin for sleep, cascara sagrada for constipation, and tons of water for dry mouth. I can't wait to see where I am at the end of June!"

10 / 10
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69 Report
  • Jen...
  • Taken for less than 1 month
  • August 29, 2019

For Weight Loss (Obesity/Overweight) "I have been taking this medicine for 20 days, and I’ve had minimal side effects. It’s made me more irritable, and the first 2 days of taking it, it made me feel a little weird. I had trouble sleeping at night for the first week and a half, but I think that’s been resolved. This gave me the kick start that I needed. I don’t know how much weight I’ve lost since starting it and will know when I go to my 1-month appointment. I’ve definitely been losing weight. It’s pointless to take this medicine if you're not actively taking steps to eat right and exercise-something that this medicine helped me kick start. I’ve been exercising every day and have been eating great. This took away all of my cravings, and I haven’t drunk any pop since taking it-that was my biggest weakness. I will post an update as soon as I know. I started at 222 lbs, and I’m 5’7"."

10 / 10
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45 Report
  • RZ1...
  • April 19, 2013

For Weight Loss (Obesity/Overweight) "I was prescribed phentermine/Adipex for weight loss after I discussed with my doctor my lack of energy being a full-time single working mother. Time and motivation were really my issues contributing to my weight. She said this would give me the motivation and 'want' to exercise and is an appetite suppressant. Those two things are very true. I work a desk job and cannot exercise until evening, so that is hard. On day 1 and 2, I was on the go all day and felt fantastic, full of energy, and very happy. On day 3, I had several negative side effects of high blood pressure, heart pounding, fatigue, insomnia. On day 4, I had the dose cut in half by my doctor. Today is Friday, day 5, and I have lost 9.5 pounds since Monday. Hoping to see more loss but slower!"

9 / 10
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80 Report
  • bcl...
  • Taken for less than 1 month
  • March 18, 2013

For Weight Loss (Obesity/Overweight) "I have been taking Adipex for 4 days now. I have lost 13 pounds somehow. I changed my eating to only intake 1000 calories a day. I take half a pill in the morning and half a pill at noon. I have severe dry mouth and drink about 10 bottles of water a day. I am having trouble sleeping for the last 2 days. I get the jitters really bad about 30 mins after I take the pill, it lasts for a few hours. No issues with my heart rate! I am hungry until my stomach hurts. I was an overeater, so it's pretty painful! With all that, this pill is worth it. I am excited about my progress so far and can't wait to see what I can get down to in a few months!"

9 / 10
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78 Report
  • Anonymous
  • September 14, 2008

For Weight Loss (Obesity/Overweight) "I began taking Adipex in August 2008. I have been sticking to my doctor's weight loss plan of a 600-calorie per day diet. It has been 6 weeks, and I have lost 23 pounds. I feel so much better and plan to continue Adipex and my diet plan until I reach my goal weight. When first beginning Adipex, I had some trouble sleeping and found that I was dizzy often. Keeping some hard candy in my purse to eat when feeling dizzy seemed to help level out my blood sugar. After the first couple of weeks, sleeping and dizziness troubles went away. I feel that with the amount of weight I have already lost in a short amount of time, this drug is totally worth any and all of the side effects that I experienced."

9 / 10
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122 Report
  • Sti...
  • Taken for 2 to 5 years
  • February 4, 2013

For Weight Loss (Obesity/Overweight) "Adipex (phentermine) is great for weight loss. I did experience minor side effects (i.e., dry mouth, insomnia). I have taken this medicine on and off for several years. I noticed rapid weight loss the first time I took it, losing over 30 pounds in the first month. I was 202 lbs when I took it the first time, and after only 1 month, I was down to about 170 lbs. I went off of the medicine for several months, didn't exercise, and returned to my original eating habits, regaining all of the weight plus some. The second time I took it, I didn't experience the same rapid weight loss I had with the first attempt, only getting down to about 182 lbs. Going for try #3 but will do it right this time with exercise and diet change for life!"

6 / 10
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73 Report
  • Aw4...
  • May 5, 2016

For Weight Loss (Obesity/Overweight) "I am 5'3, and when I started Adipex in late January, I was 202 lbs. Just now starting to slowly stop taking them by skipping days. I have had a total weight loss of 38 lbs in 3 months. The first month was the quickest results. I've eaten 1200 calories daily, drank water, and worked out extremely for 4-5 times a week. Experience headaches due to lack of water sometimes. I was dizzy when standing up too fast, had many sleepless nights from too much energy, even though my body was so tired. But I feel reborn. I feel so happy and confident. Of course, my body image isn't what I expected, but my journey has not ended yet. Adipex is a tool used to help change your lifestyle. I can't wait to say I changed my lifestyle and no longer need a pill, but I am thankful for it."

9 / 10
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56 Report
  • Amy...
  • April 20, 2015

For Weight Loss (Obesity/Overweight) "I took Adipex for the past 3 months as prescribed. I weighed 190 lbs. with type 2 diabetes and high blood pressure. The first month I lost 20 lbs. The 2nd month 4 lbs. and 3rd month 4 lbs. I played volleyball 2x a week, which helped. I could have lost more, but I hate exercising if it's not volleyball. My 1st month, the insomnia was nightly. The dry mouth was all the time. Try chewing gum. I drank more water than I'm used to, but it was good for me. Constipation was a problem. Try fiber pills or Phillips or stool softener for constipation. Lots of energy. 2nd month, sleep was better. I felt great because I could feel those 20 lbs. off and my clothes were so baggy. Lots of energy. I slightly started to want to eat. 3rd month. Total loss = 28 lbs."

9 / 10
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54 Report
  • can...
  • Taken for 1 to 2 years
  • February 21, 2013

For Weight Loss (Obesity/Overweight) "I have been on Adipex for almost two years. When they say it's not such a thing as a miracle pill, they haven't tried this. I lost 10 pounds from my goal of losing 150 pounds. My weight loss has slowed down a bit, but as long as the numbers go down and not up, I'm still happy. I did experience extremely dry mouth, dizziness, and loss of appetite for the first two months. BUT IT WAS WORTH EVERY BIT. Now I'm starting to have sleeping problems, which I don't like. I am very scared that if I stop taking it, I'm going to gain my weight back."

10 / 10
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65 Report
  • Aun...
  • Taken for less than 1 month
  • September 5, 2017

For Weight Loss (Obesity/Overweight) "Been on Adipex-P for 28 days and have lost 20 pounds. Doctor put me on it because I am menopausal and have a hard time losing weight. First week had a hard time sleeping, but now no problems. I check my blood pressure daily and no issues there. Definitely get dry mouth with it, that has been my only issue. I usually chew gum and keep a drink handy. Glad I was given this drug, doubt I would have lost what I did without it."

9 / 10
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  • FKH...
  • November 12, 2012

For Weight Loss (Obesity/Overweight) "This is a very good diet pill. I have been able to lose 15 pounds fairly easily combining Adipex with the Atkins diet. I don't have cravings, my appetite is normal and doesn't drive me crazy all day. I've been taking Adipex for about 8 months now and have no side effects whatsoever. I did try the generic brand, which was made by a different company, and I did have the side effect of not being able to sleep. So I stick with the name brand."

10 / 10
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  • JOh...
  • October 17, 2018

For Weight Loss (Obesity/Overweight) "Started Adipex 9/10/18. Female - 5’9, SW 202 lbs. I have always been thinner until steroids for arthritis over the years caused weight gain. Goal is 160 lbs. My monthly check-up at the doctor on 10/6 weighed in at 191 lbs. Today, 188 lbs. I know my diet is under what I should have, usually 700-900 calories a day, light exercise. More energetic. Curbed appetite. No eating after 5:30 supper, no sweets, chicken only for fast food (no fries). If I want a mid-day snack, it’s an apple with peanut butter. One cheat day, up to 1400 calories, water only. Have dry mouth and insomnia. Faster heartbeat when active. No rage feelings. Actually, great mood because of the energy and feeling proud of myself for losing. I will gain a little back as I will have to add more calories into my diet, but have the mindset to eat healthier, and hopefully losing the weight, I will be more energetic when off Adipex. Good luck to all."

10 / 10
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34 Report
  • Ros...
  • October 17, 2016

For Weight Loss (Obesity/Overweight) "I am 5'4" and 178 lbs. I started taking Adipex 37.5 on 10/15/16. Today is my third pill. I have no appetite, I had to force myself to eat yesterday. I can't sleep, and I feel lightheaded. I got on the scale this morning, my weight was 175. My goal is 140. I will be updating my progress every week."

5 / 10
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36 Report
  • Anonymous
  • Taken for less than 1 month
  • July 14, 2012

For Weight Loss (Obesity/Overweight) "I started taking Adipex on June 18, 2012. It has worked wonders. The only side effect I have had is terrible dry mouth, but I drink lots of water and chew gum to help with that. I skip one day a week of not taking the medicine, and to date I have lost 20 pounds. That's amazing, 20 pounds in 25 days. I do exercise daily. I walk 3 miles every day. I have lots of energy. When I first started taking the pills, I was not hungry and had to remind myself to eat. I did have a little trouble sleeping. In all, this has been a great experience, and I can't wait until I hit my goal weight."

10 / 10
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45 Report
  • RMP...
  • September 16, 2016

For Weight Loss (Obesity/Overweight) "I'm 5'5", 240 lbs. After years of exercise and dieting, I just could not seem to lose more than a few pounds. My doctor and I decided I should try Adipex. I just started taking it yesterday (9/15/16). I've noticed a few side effects even just with the first dose. I have a bit of a dry mouth, and it has caused insomnia and a bit of jitteriness too. Granted, it was my first pill, so I'm hoping these will subside after a few days. It has curbed my appetite, and I've noticed an increase in energy. Now I'm not sure if it was due to the medication, but by 5/6:00, I started to feel like I was crashing a little bit. I don't want to give this a rating yet, being as I just started, so I will update at a later time."

8 / 10
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37 Report
  • Old...
  • April 12, 2012

For Weight Loss (Obesity/Overweight) "Started taking Adipex-P 4 weeks ago. Cons: constipation and really bad bouts of insomnia - better as time has gone on. Do not take with a blood pressure pill/water pill - you will feel like crap and your heart will try to burst through your ribcage. Pros: lost 31 pounds. 17 pounds - yes, 17 pounds in 1 week, though I do attribute that to the Adipex-P blood pressure/water pill. I found I could not take both at the same time or on the same day, so I stopped taking the blood pressure pill. My blood pressure is down to where it should be. Working out 4-5 times a week. 4-5 miles of cardio per workout plus weights. Probably cut my daily calorie intake by half. I plan on taking the pill for a max of 3 months, so by summer, I should be off the pill but still have a more active life."

10 / 10
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  • Via...
  • April 21, 2009

For Weight Loss (Obesity/Overweight) "I started taking Adipex-P in June 2008. I was 193 lbs (F- 5'3'). Today I weigh 158 lbs. At first, I didn't really like the side effects: dry mouth, constipation, couldn't sleep, really bad headaches, so I went back to my doctor about a week after starting the pill. I had lost 10 lbs, I didn't want to stop. The doctor suggested I cut the pills in half and to try to eat and drink more often. It turned out that it worked for me. I would take a 30-day supply, cut the pills in half, and I don't do weekends. After that 30-day supply was done, I get off the pill for a month to make sure I don't just regain the weight. Oh, and I don't exercise or eat healthy, I just watch how much I'm eating. Also, no soda."

9 / 10
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51 Report

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