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Adipex-P and Constipation: What Users Say

Constipation: mentioned by 17 users (2.8%)

Based on user experiences from 609 Adipex-P reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dry mouth 27.3%
headaches 7.7%
insomnia 7.4%
tremors 4.3%
increased heart rate 4.1%
loss of appetite 3.4%
anxiety 3.0%
constipation 2.8%
nausea 2.6%
dizziness 2.5%

Reviews for Adipex-P

Commonly mentioned side effects
  • Kri...
  • Taken for 6 months to 1 year
  • July 19, 2014

For Weight Loss (Obesity/Overweight) "I started off on the highest mg, which is 37.5, and it has worked very well for me. In my first month, I had lost 26 lbs, and in 6 months, I lost a total of 90 lbs. I DID NOT EAT HEALTHY NOR DID I EXERCISE. I took a break from it a couple of months back because it's not safe to take it for an extended period of time due to the fact that it takes a toll on your liver. I just got back on it again yesterday. It will cause you to have DRY MOUTH, CONSTIPATION, URGES TO DRINK LOTS OF WATER, ENERGY, ABILITY TO STAY FOCUSED, INSOMNIA, FAST HEART RATE, MOOD SWINGS, NAUSEA, AND EASES BODY PAIN. I have a heart murmur and panic attacks, so after taking this medication, I notice it gets harder for me to breathe as the day goes by."

9 / 10
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331 Report
  • sar...
  • Taken for less than 1 month
  • June 5, 2015

For Weight Loss (Obesity/Overweight) "I went to a weight loss clinic on Tuesday, June 2nd. I have been battling my weight for years (ever since I had 4 kiddos). I'm 5'5, and my starting weight was 184.4 lbs. I started the prescription the same day that I had it filled, and as of today, Friday, June 5th, I am down to 177 lbs! This is absolutely unreal! 7 lbs in 3 days! I have had slight insomnia, constipation, and crazy dry mouth, all of which are easily solved. A little melatonin for sleep, cascara sagrada for constipation, and tons of water for dry mouth. I can't wait to see where I am at the end of June!"

10 / 10
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69 Report
  • Amy...
  • April 20, 2015

For Weight Loss (Obesity/Overweight) "I took Adipex for the past 3 months as prescribed. I weighed 190 lbs. with type 2 diabetes and high blood pressure. The first month I lost 20 lbs. The 2nd month 4 lbs. and 3rd month 4 lbs. I played volleyball 2x a week, which helped. I could have lost more, but I hate exercising if it's not volleyball. My 1st month, the insomnia was nightly. The dry mouth was all the time. Try chewing gum. I drank more water than I'm used to, but it was good for me. Constipation was a problem. Try fiber pills or Phillips or stool softener for constipation. Lots of energy. 2nd month, sleep was better. I felt great because I could feel those 20 lbs. off and my clothes were so baggy. Lots of energy. I slightly started to want to eat. 3rd month. Total loss = 28 lbs."

9 / 10
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54 Report

Frequently asked questions

  • Leb...
  • Taken for 1 to 6 months
  • February 24, 2016

For Weight Loss (Obesity/Overweight) "I'm 31, female. Just shy of 5'4''. I started phentermine on 12/28/15 weighing 184, now I'm in the middle of my 9th week, and I weigh 165, so in 2 months I lost 19 lbs. My goal is 145. I weigh in at my clinic every Monday evening. I do cardio and weights 4 to 6 days a week. The first 3 weeks I ate strictly protein and veggies with some fat, I've slowly added in complex carbs and fruit. I drink at least 90 oz of water a day and have 3 meals and 2-3 snacks. The days I don't work out, I only eat the 2 snacks. The side effects I've had are dry mouth, dry skin, and constipation (despite my water and fiber intake). I recommend the smooth moves tea by Traditional Medicinals, but test it one a day where you can be near a bathroom so you know how you react."

8 / 10
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44 Report
  • Anonymous
  • May 21, 2009

For Weight Loss (Obesity/Overweight) "I started taking Adipex 2 weeks ago. I weighed in at 232 lbs. As of today, I weigh 222 lbs. So I've lost 10 lbs in 2 weeks. I tried taking Alli in January along with the Special K diet and exercise and lost maybe 5 lbs. I am so excited about Adipex. It has helped me cut my portions down. I still eat normal food, just not as much. I have to force myself to eat. So far, the only side effects I've had are dry mouth, but that has helped me drink lots of water. I've also had a little constipation. I have stopped drinking Coke. I have had some, but I don't have the desire to drink it. If I get a Coke from somewhere, I only have like 3 sips out of it and end up throwing it out. I love Adipex."

10 / 10
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63 Report

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  • kik...
  • Taken for less than 1 month
  • August 17, 2012

For Weight Loss (Obesity/Overweight) "Been on Adipex for one week and lost 7 lbs. I was skeptical at first, but after exercising and dieting with no results, what did I have to lose? The doctor suggested we try it for 30 days. I'm glad I did. Side effects, at least for me, include dry mouth, constipation, and some sleeplessness. I feel that exercise is a daily must. After I exercise, I feel normal; the only difference is that I'm not hungry, nor am I interested in the donut by my desk or cake down the hall! Another point: you will not be hungry, nor interested in food; however, you must remain mindful that your body needs fuel to keep burning, so I find myself getting satisfaction from just half of a Kind bar (before I could eat 3 at once)."

9 / 10
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45 Report
  • Kre...
  • June 3, 2015

For Weight Loss (Obesity/Overweight) "I started taking Adipex 37.5 on May 29th, my first time taking this medication, but I can't seem to lose any of the weight gained from my second pregnancy. I tried dieting, exercising, and nothing happened. My current weight when I started was 248, and on the first day taking this, I felt like if I started moving, I wouldn't be able to stop. The energy it provides was amazing. So far, the only side effects I've had were dry mouth. I'm starting to get a little constipated, but I knew that was a possibility, so I'm prepared for it. I weighed myself today, and I'm down to 241. I haven't changed my eating habits, and I try to stay active for at least 30 minutes a day. I'm hoping to lose between 50-70 lbs."

8 / 10
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37 Report
  • Old...
  • April 12, 2012

For Weight Loss (Obesity/Overweight) "Started taking Adipex-P 4 weeks ago. Cons: constipation and really bad bouts of insomnia - better as time has gone on. Do not take with a blood pressure pill/water pill - you will feel like crap and your heart will try to burst through your ribcage. Pros: lost 31 pounds. 17 pounds - yes, 17 pounds in 1 week, though I do attribute that to the Adipex-P blood pressure/water pill. I found I could not take both at the same time or on the same day, so I stopped taking the blood pressure pill. My blood pressure is down to where it should be. Working out 4-5 times a week. 4-5 miles of cardio per workout plus weights. Probably cut my daily calorie intake by half. I plan on taking the pill for a max of 3 months, so by summer, I should be off the pill but still have a more active life."

10 / 10
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41 Report
  • Tau...
  • Taken for 1 to 6 months
  • July 10, 2017

For Weight Loss (Obesity/Overweight) "I am back with another update. I went on vacation, and even being surrounded by Caribbean food, cupcakes, and off my usual workout routine, I lost weight! I do suffer from constipation and thirst while on this drug. However, since May 6th, I have gone from 291 lbs to 265 lbs. I have lost over 60 pounds in four months, and I'll probably be at over 70 pounds of weight loss by the end of this month! Good luck to you all! Stay encouraged, eat well, and train your body! If you work on developing proper eating habits, the drug will take care of the rest!"

10 / 10
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28 Report
  • Via...
  • April 21, 2009

For Weight Loss (Obesity/Overweight) "I started taking Adipex-P in June 2008. I was 193 lbs (F- 5'3'). Today I weigh 158 lbs. At first, I didn't really like the side effects: dry mouth, constipation, couldn't sleep, really bad headaches, so I went back to my doctor about a week after starting the pill. I had lost 10 lbs, I didn't want to stop. The doctor suggested I cut the pills in half and to try to eat and drink more often. It turned out that it worked for me. I would take a 30-day supply, cut the pills in half, and I don't do weekends. After that 30-day supply was done, I get off the pill for a month to make sure I don't just regain the weight. Oh, and I don't exercise or eat healthy, I just watch how much I'm eating. Also, no soda."

9 / 10
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51 Report
  • 08a...
  • Taken for 1 to 6 months
  • May 8, 2012

For Weight Loss (Obesity/Overweight) "I have been taking it for almost 2 months now, and I lost 9 lbs the first month and had a lot more energy. The second month I haven't lost anything and no energy. I have had constipation, cramps, dry mouth, and insomnia. I have to go to the doctor once a month for a check-up and a new prescription. My goal is to lose 30 lbs, but at this rate, I am not going to make it. I walk 3 miles a day at a brisk walk and do a cardio workout 3 times a week, but can't seem to lose the weight like everyone else who have commented on this board."

6 / 10
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38 Report
  • TyE...
  • January 24, 2010

For Weight Loss (Obesity/Overweight) "I have been on Adipex since the beginning of December, and my starting weight was 271, and as of Thursday, I weighed in at 246. I am very pleased with my weight loss and very disappointed in myself to have reached a whopping 270. I guess it's better late than never. I do experience some side effects, which include dry mouth and constipation at times. When this happens, I drink even more water and drink a swig of vinegar, it usually helps. I have not incorporated exercise into my plan yet but plan to start next week. I wanted to get the diet down pat first. I do recommend this pill for anyone that has a lot of weight to lose!"

10 / 10
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37 Report
  • hol...
  • March 30, 2012

For Weight Loss (Obesity/Overweight) "I started taking Adipex on March 15, 2012. My starting weight was 232. My first week weighing in, I lost 7 lbs, weighing 225 lbs. I don't have too many complications, only dry mouth. I used to drink a lot of sodas, maybe 8-9 sodas a day. While taking Adipex, I only drink water. As a result of the non-sleep, my doctor also prescribed me trazodone, this is to put you to sleep. I now go to the gym and walk. I know after I stop taking the Adipex, my eating and drinking habits will change. I love this pill, the only thing is a little constipated, and that comes from not eating. My first week, I just took some stool softeners. Other than the dry mouth, constipation, and a little stomach cramps, I am good."

10 / 10
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22 Report
  • Anonymous
  • December 20, 2010

For Weight Loss (Obesity/Overweight) "I started taking the generic version 6 months ago. I had to go to my doctor every two weeks for a weigh-in and to 'earn' another prescription (had to show some weight loss). The first two days were the hardest, with nausea. I felt tired but had insomnia. I did lose 9 lbs the first 2 weeks, but after that, I have only lost about 1-1.5 lbs/week. I began working out 3-4 times a week for 30 minutes to improve muscle tone and cardio fitness. The dry mouth and constipation were bad, so I began taking the pill every other day, which really helped. I did not notice any increase in appetite. So far, I have lost 40 lbs. My doctor is thrilled and said I can continue with skipping 2-3 days. I plan on stopping when I hit 50 lb loss. I want to lose 100 lbs total."

8 / 10
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  • Anonymous
  • July 23, 2011

For Weight Loss (Obesity/Overweight) "I'm a 33-year-old male who was 198 lbs. at 5' 5'. I have been taking Adipex-P 37.5 since June 16, 2011. Five weeks later, I have lost 15 lbs. (183 lbs), that's about 3 lbs. per week. I haven't changed my meals that much, but I wasn't a big eater before. I've just cut way down on sodas and drink mostly water. Dry mouth and constipation are the only side effects I've experienced, but that is where the high amount of water intake helps. One thing I learned after starting this is that drinking ice-cold water helps you lose weight because your body burns calories trying to bring that water intake up to body temperature. My goal was to get down to 165 lbs., so after 5 weeks, I'm halfway there."

9 / 10
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13 Report
  • HDH...
  • December 10, 2015

For Weight Loss (Obesity/Overweight) "I am 5 ft and 160 lb. I'm a short, round pear. I started Adipex in September (I think). I have only lost 10 lbs. I put on a lot of weight when I started taking my thyroid medicine. I have changed up my eating habits some and have been trying to go to the gym 3 days a week and go walking with my dog on the weekends. At first, when I took it, I had light headaches, and I felt like I lost all my energy by mid-afternoon and was a little constipated. Now I feel fine. Dry mouth and still light constipation. I just thought it would work a little better for me. I am trying to eat better, it can be so hard when I have to make dinner for my hubby and make me something else and being around the holidays. I am hoping to lose 20 more pounds."

7 / 10
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10 Report
  • adi...
  • April 18, 2009

For Weight Loss (Obesity/Overweight) "I have been on Adipex for 3 weeks now, and the only changes I have noticed in me and my body are that I have horrible cotton mouth, and I am extremely constipated. I have maybe lost 1 lb since I started taking this medicine. I am extremely disappointed in this medicine, it has done nothing for me."

1 / 10
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18 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.