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Adipex-P and Nausea: What Users Say

Nausea: mentioned by 16 users (2.6%)

Based on user experiences from 609 Adipex-P reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dry mouth 27.3%
headaches 7.7%
insomnia 7.4%
tremors 4.3%
increased heart rate 4.1%
loss of appetite 3.4%
anxiety 3.0%
constipation 2.8%
nausea 2.6%
dizziness 2.5%

Reviews for Adipex-P

Commonly mentioned side effects
  • Kri...
  • Taken for 6 months to 1 year
  • July 19, 2014

For Weight Loss (Obesity/Overweight) "I started off on the highest mg, which is 37.5, and it has worked very well for me. In my first month, I had lost 26 lbs, and in 6 months, I lost a total of 90 lbs. I DID NOT EAT HEALTHY NOR DID I EXERCISE. I took a break from it a couple of months back because it's not safe to take it for an extended period of time due to the fact that it takes a toll on your liver. I just got back on it again yesterday. It will cause you to have DRY MOUTH, CONSTIPATION, URGES TO DRINK LOTS OF WATER, ENERGY, ABILITY TO STAY FOCUSED, INSOMNIA, FAST HEART RATE, MOOD SWINGS, NAUSEA, AND EASES BODY PAIN. I have a heart murmur and panic attacks, so after taking this medication, I notice it gets harder for me to breathe as the day goes by."

9 / 10
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  • Ali...
  • April 3, 2014

For Weight Loss (Obesity/Overweight) "I've been on this medicine off and on for 6 months. I've lost about 30 pounds. My cycle is 1 month on and one month off. If you take it more than a month, your body gets used to it. I have found giving the body a rest and allowing the metabolism to adjust without works best for long-term weight loss and maintaining. I started at 180, currently at 150. I get bad side effects, but seeing the scale move and clothes fit motivates me to move on. If you exercise with this medicine, it can make you nauseated and cause vomiting. Exercising first thing in the morning, then taking the medicine, works best to prevent nausea and vomiting. Also, I find it important for users to change eating habits. Suggest clean eating 6 days on, 1 day off."

8 / 10
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  • Dra...
  • Taken for less than 1 month
  • August 25, 2014

For Weight Loss (Obesity/Overweight) "I started Adipex on 8-18-14, and today is 8-25-14. I am down 8 pounds in a week. I hope this kind of weight loss continues, but I'll have to wait and see. I did experience a little bit of nausea for the first few days, but it wasn't too bad, and dry mouth a little. So far I am pretty pleased."

10 / 10
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166 Report

Frequently asked questions

  • MKm...
  • Taken for 1 to 6 months
  • May 17, 2016

For Weight Loss (Obesity/Overweight) "Been on generic Adipex for 1 month. Start weight 183. Current weight 171. Drink lots of water on this. Dehydration can cause headaches (I get migraines already, so this did not increase due to the medication). The first day I was nauseous. The first week was extreme dry mouth and complete lack of appetite. I had to remind myself to eat during the first week. At some point during the second week, I was feeling a bit hungry but not the constant hunger I experienced before. As of the end of the first month, the only persisting side effect is the dry mouth. I'm also not sleeping very well! But I just take Tylenol PM for that. Overall, I feel good. I'm losing weight. I'm less hungry, so I'm selecting better food choices. (Chocoholic lol) and no serious issues."

10 / 10
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  • Zul...
  • Taken for less than 1 month
  • March 7, 2017

For Weight Loss (Obesity/Overweight) "I started Adipex last Tuesday, 2/28/17. My starting weight is 208, today, 3/6/17, my weight is 190.3. I'm amazed with this pill. The first day, I felt a very slight headache, I thought it was because I didn't have my regular cup of coffee, so I had one. I experienced slight nausea, but it didn't last long. It's amazing how my appetite has decreased, and I can't eat my meal completely. Until yesterday, I didn't even feel hungry. Today, I felt hungry around 10:30 am and ate just a 1/3 of a protein bar. At 12, I had half of the leftovers from yesterday's dinner because I had no desire to finish. I'm very happy so far. Also, I have no problems sleeping. I take my pill every morning at 7 and eat a protein bar for breakfast an hour later with 16 oz of water. Total: 10 daily."

9 / 10
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41 Report

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  • Anonymous
  • Taken for 1 to 6 months
  • March 18, 2015

For Weight Loss (Obesity/Overweight) "I was personally not on this pill, but my mom was and currently still is. Though she has lost about 20 lbs in the last month or so, she has been experiencing side effects. First off, she's had severe headaches since starting the medicine. She's had extreme mood swings and is very nauseous and dizzy at times."

1 / 10
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57 Report
  • jes...
  • July 1, 2011

For Weight Loss (Obesity/Overweight) "I started Adipex June 17th, and it's now July 1st. My starting weigh-in was 268, and 2 weeks later I weigh 240. I take half a pill when I wake up, then another half around 2 pm. It has suppressed my appetite so much it's crazy. I never realized how much I was eating before. It is important to exercise regularly. I have noticed with this pill that just looking at carbs makes me nauseous. I love lasagna, and my mother made some, but I just couldn't eat it. Also, I have been drinking a ton of water because the dry mouth side effect has hit me hard. Overall, yes, I am excited with my weight loss. I just hope it keeps up at this rate. 100 lbs to go!"

10 / 10
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42 Report
  • Sav...
  • Taken for less than 1 month
  • June 16, 2021

For Weight Loss (Obesity/Overweight) "The first day I took this medicine, I had so much energy and was extremely focused. The second day was a little different (I am prescribed the dosage of 37.5 mg/day). The second day, my appetite was gone all day, and toward the later afternoon, I started throwing up. I could not eat any food that day. Now comes day three, I take the medicine again, hoping that I wouldn't have the same reaction as the day before, and I was right, but everything worsened. I still haven't gotten my appetite back, and I've thrown up seven times today and cannot hold any water or anything down without throwing up two minutes later. I haven't had food in two days because of the constant nausea and vomiting. If you have a sensitive stomach, beware."

2 / 10
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16 Report
  • Ash...
  • Taken for less than 1 month
  • October 5, 2016

For Weight Loss (Obesity/Overweight) "I took 37.5 at 7:00 am. The first five minutes, I felt a warm sensation all over; about 20 minutes later, I felt as if my body was drunk and heavy. Then a burst of energy came; I could not stop moving for the next 4 hours. I detailed, cleaned my whole house. I could not eat (eat before the pill); food was a turnoff for me. I felt full and satisfied with 2 crackers. I only gave it a 7 because I was very nauseous. I vomited without warning on my floor. Stayed pretty sick to my stomach all day. I lost 2 lbs the first day."

8 / 10
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29 Report
  • Anonymous
  • January 4, 2012

For Weight Loss (Obesity/Overweight) "Started at 205, 5'4", age 30 female. Experienced the traditional side effects of initial dry mouth, jitters, and sweating, but also lost the interest in eating. All thoughts of eating (especially when bored) went away, found that most often when others were eating or even the smell of food no longer turned my hunger on and in some cases made me queasy. Next, my mental focus and energy skyrocketed, and I was able to complete projects with more quality and determination than ever before. The pounds melted away with virtually little exercise. Lost 25 lbs in the first three months, cannot wait to lose the next 25 and am now including a workout regimen I'm doing at home with the Wii."

10 / 10
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25 Report
  • Bus...
  • Taken for less than 1 month
  • February 26, 2014

For Weight Loss (Obesity/Overweight) "Update after 7 days: Starting weight: 161.4 lbs Current weight: 158.4 lbs I started off taking a 1/2 tablet in the morning, 30 mins before breakfast. The first few days were okay, took the edge off hunger for sure, but I felt unfocused. On day 5, I traveled out of town and started feeling a little nauseous, so I held this medicine on days 6 and 7. I slept so much these two days and was very hungry. I was just so relieved to not be nauseated that I allowed myself to eat some not-so-healthy foods on these two days. This is partly why I do not think I lost much weight this first week. I started back on my 1/2 tablet regimen this morning and feel quite good. I think the nausea may have been related to a certain food I had eaten."

8 / 10
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36 Report
  • Red...
  • Taken for less than 1 month
  • February 3, 2017

For Weight Loss (Obesity/Overweight) "I started Adipex-P 1-25-17. The first day, within 30 mins of taking it, I was nauseated and started choking down water, trying not to vomit. Sadly, I did anyway. Afterwards, I continued the water, the nausea settled, and I decided to try it the next day. So far, it's been 10 days on a 1300 calorie diet & workout 3-5 times a week and drinking mostly water, only juice once a week, and I'm down 9 lbs. I'm 35 and very overweight, with a goal from the doctor of 31 lbs lol and that is me being reasonable. Anyway, weight loss is a struggle, and I wish everyone success with their goals, but I think it's worth trying!"

8 / 10
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18 Report
  • Anonymous
  • December 20, 2010

For Weight Loss (Obesity/Overweight) "I started taking the generic version 6 months ago. I had to go to my doctor every two weeks for a weigh-in and to 'earn' another prescription (had to show some weight loss). The first two days were the hardest, with nausea. I felt tired but had insomnia. I did lose 9 lbs the first 2 weeks, but after that, I have only lost about 1-1.5 lbs/week. I began working out 3-4 times a week for 30 minutes to improve muscle tone and cardio fitness. The dry mouth and constipation were bad, so I began taking the pill every other day, which really helped. I did not notice any increase in appetite. So far, I have lost 40 lbs. My doctor is thrilled and said I can continue with skipping 2-3 days. I plan on stopping when I hit 50 lb loss. I want to lose 100 lbs total."

8 / 10
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21 Report
  • bri...
  • April 25, 2011

For Weight Loss (Obesity/Overweight) "I am a 27-year-old 5'2" woman. My weight started at 242 lbs on March 1st. I lost 8 lbs in a month, teaching myself how to eat right. I just went to the doctor on April 21st, and he gave me Adipex for 30 days. I started taking it on the 22nd, and today is the 25th, and I have lost 7 lbs in 4 days. I do have dry mouth, nausea, and a headache at night, and I have trouble sleeping. I don't have that burst of energy I hear so many talk about. I have not started working out yet, but tonight I will start that. I, too, do not crave sweets, and I also am a huge Coke drinker, and I haven't wanted one since I started. All I want is water, and that's a good thing. This is my first time taking Adipex, and so far I am very happy with it."

10 / 10
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14 Report
  • HOT...
  • November 18, 2009

For Weight Loss (Obesity/Overweight) "I have been on Adipex-P for 1 week now and have lost 5 lbs. I have experienced loss of appetite, dry mouth, headaches, nausea, jitters, loss of memory, and have a bad taste in my mouth. I'm pleased with the weight loss, but the side effects are bothersome, so after I am done with this month's supply, I'll stop. Starting weight 181 lbs."

8 / 10
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15 Report
  • Anonymous
  • June 8, 2009

For Weight Loss (Obesity/Overweight) "Caused dizziness and nausea initially. Did lose some weight but worried about the side effects, so stopped."

4 / 10
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18 Report

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