Perphenazine and Tardive Dyskinesia: What Users Say

• Eri...
• Taken for 2 to 5 years
• December 21, 2012

For Psychosis "I have been on Trilafon (perphenazine) for about 4 years. I'm on a low dose, 4 mg x 3 times a day. From what I understand, this medicine is a lot more gentle than most medicines that would treat bipolar, schizophrenia, and other forms of psychosis. It's not good for the elderly, as the higher the dosage you get, the more at risk you are for tardive dyskinesia (or tremors of the face, arms, and hands). I am 28, and this medicine worked when Lexapro, Geodon, Haldol, and risperidone wouldn't. I am given it for psychosis. In addition, I am on 40 mg Viibryd and 0.5 mg of Klonopin. I would recommend this medicine."

• A...
• November 2, 2021

For Bipolar Disorder "When loxapine was discontinued, I was put on perphenazine. I have to say this is a true miracle drug for me. Not only do I have rapid cycling bipolar I, but also generalized anxiety disorder and panic disorder. This drug has greatly helped with all three. I have less anxiety and panic attacks, and my manic episodes are better controlled. Of course, I still have all these things, and it has gotten worse as I get older, this drug helps. The only thing I have noticed is some sexual side effects if my dose is too high and a more pronounced occurrence of my tardive dyskinesia, which I unfortunately have some permanently from taking Haldol for too many years. But there are good meds to control that as well. Try it if you respond better to older meds, especially if you have anxiety too. You won't be disappointed! I take 8 mg a day. A low dose, I realize, but any higher, and I have the above issues. And I have other drugs to control my illnesses as well."

• BKa...
• October 8, 2020

For Psychosis "I was put on this drug, perphenazine, when my psychosis got 'a little' out of hand after other medications failed. I experienced a very rapid recovery while on Peratsin (perphenazine) and did not need long-term therapy on the drug. I start the drug occasionally when rapid thoughts and feelings of mania/psychosis start to appear, always helping to resolve and stabilize me. It worked wonders for me, but I do know the dangers of the drug, like developing tardive dyskinesia, which scares me."