Ibrance and Mouth Sores: What Users Say

• 15...
• Taken for 1 to 2 years
• June 7, 2017

For Breast Cancer, Metastatic "I had stage 2 breast cancer in 2002. In 2009, found Mets to the spine at T12 vertebrae and has moved to the lumbar spine and right hip. Was on Zometa, letrozole, and am now taking Ibrance, Xgeva, and Faslodex injections monthly for the past year. My last scan showed areas of Mets are smaller, my doctor doesn't think I need any further scans unless I develop other symptoms related to organ Mets. I have never had a low white count, however, I have most other side effects. Mouth sores in the beginning, poor appetite, taste and smell issues. Also, toe problems, it started with the last 3 toes on both feet tingling and now have neuropathy pretty bad in both feet and now hands. I don't feel great, but I am able to enjoy life and grateful to still be here. I will take any drug to stay alive!"

• Jaj...
• Taken for 1 to 6 months
• January 15, 2017

For Breast Cancer, Metastatic "I was so hopeful that the wonder drug Ibrance would help me, but it didn't do squat. Actually, I am worse off now than before. It seems to have triggered something to make my mets spread. Side effects: mild to moderate. Bad fatigue and mouth sores. Insurance out of pocket would have been $60 a month, but copay assistance made it only $10."

• Gra...
• Taken for 6 months to 1 year
• January 28, 2021

For Breast Cancer, Metastatic "I was started on Ibrance in March 2020. I had a lot of weakness and abnormal labs when I first started taking it. I was also getting radiation, which contributed. After a couple of months, I was better and able to return to work. Since that time, I have had a few minor side effects: a sore mouth and some rash from time to time, but nothing I couldn’t handle. From March to October, my cancer antigens dropped from 258 to 66. In November, I had COVID, and it has all been downhill. Not sure if that plays any part or not. Since December, I have required to be in the hospital for pain, have gone through a second course of radiation, and my cancer antigen has gone back up and now back to 201. Right now, my bone pain is so bad I can barely walk to the bathroom. When I try to even sit up, the pain is bad. My oncologist has taken me off the Ibrance and is in the process of changing my drug regimen."

• Can...
• Taken for 1 to 6 months
• December 9, 2020

For Breast Cancer, Metastatic "Was on Ibrance and Letrozole for 3 months, possibly the worst of my life. Could not complete 1 single cycle (started 3 in total). White cells nosedived after 15 days. Side effects included mouth ulcers, diarrhea, skin peeling on my fingers and feet soles, extreme fatigue, joint pains. After 3 months, recurrence in axillary lymph nodes + bone lesions. Going back now to chemo. Almost happy about that since it means the end of Ibrance."