Skip to main content

User Reviews for Omeprazole / sodium bicarbonate

Also known as: Zegerid, Zegerid OTC

Omeprazole / sodium bicarbonate has an average rating of 8.3 out of 10 from a total of 36 ratings on Drugs.com. 78% of reviewers reported a positive effect, while 9% reported a negative effect.

Condition Avg. Rating Reviews Compare
GERD  
8.2
27 reviews 220 medications
Stomach Ulcer  
10.0
4 reviews 98 medications
Erosive Esophagitis  
10.0
3 reviews 102 medications
Duodenal Ulcer  
1.0
1 reviews 129 medications
Gastrointestinal Hemorrhage  
10.0
1 reviews 16 medications
Summary of Omeprazole / sodium bicarbonate reviews 8.3 36 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Omeprazole / sodium bicarbonate

Anonymous April 29, 2008

Zegerid (omeprazole / sodium bicarbonate) for GERD: “Using it as a replacement for Nexium, since insurance refused to cover Nexium. Works like a charm, and my GERD is under control now. Sometimes it's a bit of a hassle to have to wait half an hour before eating in the morning, especially when in a hurry, but this is an incredibly mild inconvenience when compared to the benefits.”

10 / 10
Was this helpful?YesNo
Anonymous December 8, 2008

Zegerid (omeprazole / sodium bicarbonate) for GERD: “I was diagnosed with acid reflux at 14 and always had heartburn. But after a while pain accompanied the heartburn and began to wake me up in the middle of the night and would not let me go back to sleep. My doctor assumed it was an ulcer and decided to put me on Pepcid AC and Nexium, one tablet each a day. I was still in a quite a bit of pain. and when I went to see a specialist they preformed an endoscopy and found that i had a severe case of gastritis. They prescribed me Zegerid and the difference was unbelievable. After about a week I was completely pain free. No more heartburn or pain. But I always have to make sure I take it once a day or else ill pay for it the next day. Overall, I don't know what I would do without it.”

10 / 10
Was this helpful?YesNo
Anonymous · Taken for 1 to 6 months October 23, 2013

Zegerid (omeprazole / sodium bicarbonate) for Stomach Ulcer: “this is the best ulcer medicine on the market. it eliminated my pain within a few days after being doubled over and unable to go to work. it is the only one that actually heals existing ulcers. I have ulcers and an enlarged esophagus and this med is incredible. it is a miracle drug.”

Was this helpful?YesNo
Anonymous September 8, 2008

Zegerid (omeprazole / sodium bicarbonate) for GERD: “I've been taking this for nearly a year now, and I can honestly say I've been heartburn-free since the day after I started taking it. I can eat all the things that I love but used to keep me up all night (tomato sauce, bananas and peanut butter were the worst). It is quite expensive, about a $1 a pill with insurance, but worth every penny. It's can also be a hassle because I have to wait to eat in the morning after I take it, but I am able to get something at work. I took Tagamet for a while, then Zantac (75 and then 150), and both those stopped working after a few months. Tums, Rolaids and all the other chewables, and liquids like Mylanta all quit working years ago. My doctor decided to step it up and prescribe this to me and my life changed.”

10 / 10
Was this helpful?YesNo
Cough-free June 8, 2010

Zegerid (omeprazole / sodium bicarbonate) for GERD: “I had no symptoms of GERD, but a nagging chronic cough that seemed to originate from the back of my throat, not from my lungs. It would occur suddenly and without any warning. I could get relief from popping a Hall's cough drop, but my cough was so frequent (about 20 times a day). I was also clearing my throat all the time. My voice became gravelly at times, too. My co-workers were giving me grief over this cough. After trying several medications, my PCP referred me to a gastroenterologist, who gave prescribed Zegerid. I took 40 mg twice daily. My cough improved over the next 3 days, and disappeared. It has been almost a month. However, that nagging cough is beginning to creep back, along with the throat-clearing and gravel-voice.”

9 / 10
Was this helpful?YesNo
Chuck S August 29, 2009

Zegerid (omeprazole / sodium bicarbonate) for GERD: “I have had acid reflux for over 16 years. Started with tums/rolaids and they offered some relief if I ate about 10 per day! Then I started on Prevacid, and it worked fine for a year or two, but still had some heartburn. Then tried Prilosec OTC since it was so cheap and it worked almost as good as Prevacid. Then a year ago my doctor started me on Zegerid, and it completely took away the heartburn. Now I have to make sure that I take it at least 15 minutes before I eat anything or I get wicked bad burps! An hour is best. Anyways I have been experiencing some side effects, so I may stop taking to see if they go away. I have been getting some dizziness, headaches, bad gas, stomach pain, and anxiety. They usually are mild.”

6 / 10
Was this helpful?YesNo
Kafitz October 8, 2009

Zegerid (omeprazole / sodium bicarbonate) for GERD: “I have had Gastroesophageal Reflux Disease for many years and in February of this year, I was diagnosed with a Hiatus hernia as well. I had been on Prilosec since the late 90s, before it was available over the counter, prior to that I took Zantac 150. After I was diagnosed with the Hiatus Hernia this year, my gastroenterologist prescribed Zegerid and within the first day of taking it, I noticed a dramatic difference no heartburn or reflux at all. I do still have to take Mylanta occasionally depending on what I eat but, that is nothing compared to what it was like. I was taking several doses of Mylanta every day with minimal relief.”

9 / 10
Was this helpful?YesNo
Samps · Taken for 1 to 6 months February 13, 2019

Zegerid (omeprazole / sodium bicarbonate) for GERD: “Zegerid is the only heartburn treatment that has ever worked for me. I’ve had bad heartburn for years. My neighbor told me about this one and how it helped her. I tried it and couldn’t believe it totally prevented any heartburn no matter what I ate. I recommend this to anyone who has to take tums or anything else for heart burn. Two family members now take it and they can’t believe it totally cleared up their heartburn. I take one every morning. This is like a miracle to me.!!!”

10 / 10
Was this helpful?YesNo
McT · Taken for 5 to 10 years December 11, 2018

Zegerid OTC (omeprazole / sodium bicarbonate) for GERD: “Zegerid is the only OTC that helps relieve the incredible pain I experience - within 15 minutes! My life would be a living nightmare without Zegerid. Nexium takes way too long to then even barely reduce the pain. I've been taking Zegerid almost daily for around 9 years. When I wait too long, the pain can be best described as Chuckie the horror doll sitting on my head and stabbing daggers down my throat and in my ears. Not fun. Thank you Zegerid, for being fast acting and highly effective!”

10 / 10
Was this helpful?YesNo
Skweeks · Taken for 1 to 2 years July 29, 2015

Zegerid (omeprazole / sodium bicarbonate) for Stomach Ulcer: “I have had problems with ulcers all my life and now I have Barrett's Esophagus to go with it. I've taken all proton pump inhibitors known to man. Zegerid is the only one that relieves the pain immediately, you don't have to wait days for it to start working. I love Zegerid , is been the only one to work for me Insurance don't want to pay for it and it's really expensive, so my doctor has to call them and explain why it is medically necessary.”

10 / 10
Was this helpful?YesNo
Abbycarmen January 23, 2016

Zegerid (omeprazole / sodium bicarbonate) for Erosive Esophagitis: “None of the other brands has functioned for me like Zegerid.c. I have used others for a long time without any results. This costs more but it the only one that works. No other choice. ”

10 / 10
Was this helpful?YesNo
Pty · Taken for 5 to 10 years December 23, 2016

Zegerid (omeprazole / sodium bicarbonate) for GERD: “This only drug, after my doctor tried several, that works for me. The packets are the best but since Medicare supplements rx does not want to cover the price went up to 3000 for 90 days. So I'm on the generic pill because of the expense. Since this drug puts me in donut hole with medicare a month supply of this generic drug cost over 400 dollars. So you pay. We suffer the affects while these drug companies are make a killing. This a really really good drug for stomach suffers.”

10 / 10
Was this helpful?YesNo
bay area boi July 22, 2011

Zegerid (omeprazole / sodium bicarbonate): “This is the best medicine for heartburn, reflux, gastritis, and etc. I had stomach problems for the longest until I took Zegerid. Prilosec didn't work for me, neither anything else. I'm finally happy, downside, I have to take one at least once a day or I'll be hurting in the stomach. After I got a endoscopy on me and the biopsy was normal, I possibly got to take this pill for the rest of my life and I'm only 24. I have mild gastritis.”

10 / 10
Was this helpful?YesNo
Tina · Taken for 1 to 6 months September 30, 2020

Zegerid (omeprazole / sodium bicarbonate) for GERD: “I have Gerd/gastritis that comes and goes and has for years. Recently I had a terrible bout as I have in the past and ever time I take Zegerid and it’s like a miracle drug. I literally feel awful, heart palpitations, nausea, no appetite, regurgitation of food. I have tried everything and Zegerid is the best.”

10 / 10
Was this helpful?YesNo
DauphinNana March 11, 2011

Zegerid (omeprazole / sodium bicarbonate) for GERD: “Zegerid is the best medicine for GERD I've ever taken. However, I'm wondering if continue usage of Zegerid as it has caused problems with my finger/toe nails. For the recent two-three years my nails have become both brittle and soft. Can't seem to have nice nails anymore. ”

10 / 10
Was this helpful?YesNo
researcherintexas3*99568 November 7, 2015

Zegerid (omeprazole / sodium bicarbonate) for GERD: “Relieves the indigestion & esophagus contractions, Side effects are disastrous!. And this is with me taking it only twice a week! 1. Irregular heart beat 2. Stiff painful knees 3. Extremely sore, tender feet 4. Hair loss 5. Blurred vision/ dry eyes 6. Insomnia 7. Swollen legs and feet Podiatrist was alarmed at my swollen feet & ankles. He immediately recommended tests/MRI to find out why. Heart/vein problems were suspected. Conclusion- arthritis. Nope- I discontinued Zegerid and ALL of the above problems are gone, most within 10 days. Baking soda is also a culprit. Solution for GERD? small meals w/out grease or cooked tomatoes(for me). Small adjustment for so much relief! I FEEL SO MUCH BETTER! I now RESEARCH ALL MEDS!”

1 / 10
Was this helpful?YesNo
rlone · Taken for 1 to 6 months July 26, 2017

Zegerid (omeprazole / sodium bicarbonate) for GERD: “Had horrible GERD. Took multiple meds including omeprazole. Scheduled EGD procedure. After one week of Zegrid symtoms totally gone and have stayed gone. Cancelled surgery. Stuff is a life saver. I was so miserable before. What a relief!”

Was this helpful?YesNo
Robyn Sweeney January 21, 2014

Zegerid OTC (omeprazole / sodium bicarbonate) for GERD: “I have used all and just about every heartburn medicine OTC and prescription. Zegerid is by far the best product I have ever used. I recommend it to all it is a little pricey but is well worth the money.”

10 / 10
Was this helpful?YesNo
Mabelle · Taken for 2 to 5 years October 2, 2017

Zegerid (omeprazole / sodium bicarbonate) for GERD: “After taking this medication for a while, I developed symptoms that were very similar to a heart attack with intermittent palpitations lasting over five minutes each, raising blood pressure, dizziness, tightness on my chest, horrible heart burn. It has cause me a severe gastritis that irritated my stomach in such a way that I was unable to consume regular meals for weeks and weeks until I stop ZEGRID OTC. My experience was a nightmare that lasted more than just a couple of months. Until I figured that ZEGRID OTC was the cause of my illness.”

Was this helpful?YesNo
Anonymous · Taken for 2 to 5 years July 22, 2013

Zegerid (omeprazole / sodium bicarbonate) for Stomach Ulcer: “I am a 46 year old female diagnosed with Barretts Esophagus 9 years ago... have had GERD since age 16. Have also had a Nissen Fundoplication surgery 2 years ago. Have been on proton pump inhibitors off and on most of my adult life. Zegrid is the only medication that comes close to working. I do take with another medication in the evenings.”

10 / 10
Was this helpful?YesNo
Moo Roo Mary March 22, 2008

Zegerid (omeprazole / sodium bicarbonate) for Gastrointestinal Hemorrhage: “Changed my life in a day. I went from complete misery to almost back to normal witin eight hours. The hour it began to wear off, my agony was back again. For me it really workd. I am taking double the prescribed dose however.”

10 / 10
Was this helpful?YesNo
BaxterBailey February 17, 2011

Zegerid OTC (omeprazole / sodium bicarbonate) for GERD: “This is the only medication that stopped my GERD. After the 14 day treatment, the first day I did not take it, my GERD returned in full force. I wish it would have had a longer effect. Have given up on my doctor finding a solution, so will have to suffer for the next four months until I can repeat the Zegerid.”

8 / 10
Was this helpful?YesNo
Anonymous May 13, 2008

Zegerid (omeprazole / sodium bicarbonate): “My symptoms, including persistent nagging cough, resolved within four (4) weeks of beginning this medicine. However, after being symptom free for almost 3-6 months, my symptoms returned. I am now taking double the dose, but have yet to experience the resolution I had initially.”

6 / 10
Was this helpful?YesNo
Pac · Taken for less than 1 month August 9, 2018

Zegerid (omeprazole / sodium bicarbonate) for Erosive Esophagitis: “Barrett’s Disease, heartburn worse since going off Zegerid a year ago. Gastric Dr ordered prescription Omeprazole 2 weeks ago and it did not help with heartburn. So I chose to go back on Zegerid 3 days ago and I am doing great! I buy it OTC at Walmart and it is CHEAPER THAN THE RX that did not help. I went through this same thing a couple of years ago and "found" OTC Zegerid was helpful whereas the rx was not.”

Was this helpful?YesNo
Anonymous August 13, 2010

Zegerid OTC (omeprazole / sodium bicarbonate) for GERD: “This medication works as well as Prilosec but the super fat pill makes swallowing very difficult, which is why I quit using it and why I have it a low rating. Most people with GERD suffer from an inflamed esophagus and the creators of this pill should have taken that into account. I went back to Prilosec after a week of painfully trying to swallow this pill.”

4 / 10
Was this helpful?YesNo

This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.