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User Reviews for Omeprazole/sodium bicarbonate to treat GERD

Also known as: Zegerid, Zegerid OTC

Omeprazole/sodium bicarbonate has an average rating of 8.2 out of 10 from a total of 23 ratings for the treatment of GERD. 78% of those users who reviewed Omeprazole/sodium bicarbonate reported a positive effect, while 9% reported a negative effect.

Omeprazole/sodium bicarbonate Rating Summary

8.2/10 average rating

23 ratings from 24 user reviews.

Compare all 110 medications used in the treatment of GERD.

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Reviews for Omeprazole/sodium bicarbonate

Susie November 19, 2020

Zegerid (omeprazole / sodium bicarbonate): “I have been using Zegerid for awhile and it works good for me. When I don’t take it and use other acid reflux I get sick and have heart burn.”

10 / 10
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Tina · Taken for 1 to 6 months September 30, 2020

Zegerid (omeprazole / sodium bicarbonate): “I have Gerd/gastritis that comes and goes and has for years. Recently I had a terrible bout as I have in the past and ever time I take Zegerid and it’s like a miracle drug. I literally feel awful, heart palpitations, nausea, no appetite, regurgitation of food. I have tried everything and Zegerid is the best.”

10 / 10
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Addie July 31, 2020

“This product omeprazole/sodium bicarbonate caused severe constipation. I noticed it after 3 days of use. It worked for my acid Reflux, but gave me this "Rare" side effect. Had to discontinue using.”

4 / 10
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Anonymous April 29, 2008

Zegerid (omeprazole / sodium bicarbonate): “Using it as a replacement for Nexium, since insurance refused to cover Nexium. Works like a charm, and my GERD is under control now. Sometimes it's a bit of a hassle to have to wait half an hour before eating in the morning, especially when in a hurry, but this is an incredibly mild inconvenience when compared to the benefits.”

10 / 10
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Anonymous December 8, 2008

Zegerid (omeprazole / sodium bicarbonate): “I was diagnosed with acid reflux at 14 and always had heartburn. But after a while pain accompanied the heartburn and began to wake me up in the middle of the night and would not let me go back to sleep. My doctor assumed it was an ulcer and decided to put me on Pepcid AC and Nexium, one tablet each a day. I was still in a quite a bit of pain. and when I went to see a specialist they preformed an endoscopy and found that i had a severe case of gastritis. They prescribed me Zegerid and the difference was unbelievable. After about a week I was completely pain free. No more heartburn or pain. But I always have to make sure I take it once a day or else ill pay for it the next day. Overall, I don't know what I would do without it.”

10 / 10
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Anonymous September 8, 2008

Zegerid (omeprazole / sodium bicarbonate): “I've been taking this for nearly a year now, and I can honestly say I've been heartburn-free since the day after I started taking it. I can eat all the things that I love but used to keep me up all night (tomato sauce, bananas and peanut butter were the worst). It is quite expensive, about a $1 a pill with insurance, but worth every penny. It's can also be a hassle because I have to wait to eat in the morning after I take it, but I am able to get something at work. I took Tagamet for a while, then Zantac (75 and then 150), and both those stopped working after a few months. Tums, Rolaids and all the other chewables, and liquids like Mylanta all quit working years ago. My doctor decided to step it up and prescribe this to me and my life changed.”

10 / 10
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Cough-free June 8, 2010

Zegerid (omeprazole / sodium bicarbonate): “I had no symptoms of GERD, but a nagging chronic cough that seemed to originate from the back of my throat, not from my lungs. It would occur suddenly and without any warning. I could get relief from popping a Hall's cough drop, but my cough was so frequent (about 20 times a day). I was also clearing my throat all the time. My voice became gravelly at times, too. My co-workers were giving me grief over this cough. After trying several medications, my PCP referred me to a gastroenterologist, who gave prescribed Zegerid. I took 40 mg twice daily. My cough improved over the next 3 days, and disappeared. It has been almost a month. However, that nagging cough is beginning to creep back, along with the throat-clearing and gravel-voice.”

9 / 10
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Chuck S August 29, 2009

Zegerid (omeprazole / sodium bicarbonate): “I have had acid reflux for over 16 years. Started with tums/rolaids and they offered some relief if I ate about 10 per day! Then I started on Prevacid, and it worked fine for a year or two, but still had some heartburn. Then tried Prilosec OTC since it was so cheap and it worked almost as good as Prevacid. Then a year ago my doctor started me on Zegerid, and it completely took away the heartburn. Now I have to make sure that I take it at least 15 minutes before I eat anything or I get wicked bad burps! An hour is best. Anyways I have been experiencing some side effects, so I may stop taking to see if they go away. I have been getting some dizziness, headaches, bad gas, stomach pain, and anxiety. They usually are mild.”

6 / 10
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Kafitz October 8, 2009

Zegerid (omeprazole / sodium bicarbonate): “I have had Gastroesophageal Reflux Disease for many years and in February of this year, I was diagnosed with a Hiatus hernia as well. I had been on Prilosec since the late 90s, before it was available over the counter, prior to that I took Zantac 150. After I was diagnosed with the Hiatus Hernia this year, my gastroenterologist prescribed Zegerid and within the first day of taking it, I noticed a dramatic difference no heartburn or reflux at all. I do still have to take Mylanta occasionally depending on what I eat but, that is nothing compared to what it was like. I was taking several doses of Mylanta every day with minimal relief.”

9 / 10
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Samps · Taken for 1 to 6 months February 13, 2019

Zegerid (omeprazole / sodium bicarbonate): “Zegerid is the only heartburn treatment that has ever worked for me. I’ve had bad heartburn for years. My neighbor told me about this one and how it helped her. I tried it and couldn’t believe it totally prevented any heartburn no matter what I ate. I recommend this to anyone who has to take tums or anything else for heart burn. Two family members now take it and they can’t believe it totally cleared up their heartburn. I take one every morning. This is like a miracle to me.!!!”

10 / 10
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McT · Taken for 5 to 10 years December 11, 2018

Zegerid OTC (omeprazole / sodium bicarbonate): “Zegerid is the only OTC that helps relieve the incredible pain I experience - within 15 minutes! My life would be a living nightmare without Zegerid. Nexium takes way too long to then even barely reduce the pain. I've been taking Zegerid almost daily for around 9 years. When I wait too long, the pain can be best described as Chuckie the horror doll sitting on my head and stabbing daggers down my throat and in my ears. Not fun. Thank you Zegerid, for being fast acting and highly effective!”

10 / 10
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Pty · Taken for 5 to 10 years December 23, 2016

Zegerid (omeprazole / sodium bicarbonate): “This only drug, after my doctor tried several, that works for me. The packets are the best but since Medicare supplements rx does not want to cover the price went up to 3000 for 90 days. So I'm on the generic pill because of the expense. Since this drug puts me in donut hole with medicare a month supply of this generic drug cost over 400 dollars. So you pay. We suffer the affects while these drug companies are make a killing. This a really really good drug for stomach suffers.”

10 / 10
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DauphinNana March 11, 2011

Zegerid (omeprazole / sodium bicarbonate): “Zegerid is the best medicine for GERD I've ever taken. However, I'm wondering if continue usage of Zegerid as it has caused problems with my finger/toe nails. For the recent two-three years my nails have become both brittle and soft. Can't seem to have nice nails anymore. ”

10 / 10
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rlone · Taken for 1 to 6 months July 26, 2017

Zegerid (omeprazole / sodium bicarbonate): “Had horrible GERD. Took multiple meds including omeprazole. Scheduled EGD procedure. After one week of Zegrid symtoms totally gone and have stayed gone. Cancelled surgery. Stuff is a life saver. I was so miserable before. What a relief!”

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Robyn Sweeney January 21, 2014

Zegerid OTC (omeprazole / sodium bicarbonate): “I have used all and just about every heartburn medicine OTC and prescription. Zegerid is by far the best product I have ever used. I recommend it to all it is a little pricey but is well worth the money.”

10 / 10
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Mabelle · Taken for 2 to 5 years October 2, 2017

Zegerid (omeprazole / sodium bicarbonate): “After taking this medication for a while, I developed symptoms that were very similar to a heart attack with intermittent palpitations lasting over five minutes each, raising blood pressure, dizziness, tightness on my chest, horrible heart burn. It has cause me a severe gastritis that irritated my stomach in such a way that I was unable to consume regular meals for weeks and weeks until I stop ZEGRID OTC. My experience was a nightmare that lasted more than just a couple of months. Until I figured that ZEGRID OTC was the cause of my illness.”

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BaxterBailey February 17, 2011

Zegerid OTC (omeprazole / sodium bicarbonate): “This is the only medication that stopped my GERD. After the 14 day treatment, the first day I did not take it, my GERD returned in full force. I wish it would have had a longer effect. Have given up on my doctor finding a solution, so will have to suffer for the next four months until I can repeat the Zegerid.”

8 / 10
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Anonymous August 13, 2010

Zegerid OTC (omeprazole / sodium bicarbonate): “This medication works as well as Prilosec but the super fat pill makes swallowing very difficult, which is why I quit using it and why I have it a low rating. Most people with GERD suffer from an inflamed esophagus and the creators of this pill should have taken that into account. I went back to Prilosec after a week of painfully trying to swallow this pill.”

4 / 10
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Sleep easy · Taken for 10 years or more November 1, 2017

Zegerid (omeprazole / sodium bicarbonate): “Great product. Works very quickly and keeps the heart burn away. A little expensive but its the best product I have found. I don't have heart burn constantly so its nice to have a product I can just take as needed”

9 / 10
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researcherintexas3*99568 November 7, 2015

Zegerid (omeprazole / sodium bicarbonate): “Relieves the indigestion & esophagus contractions, Side effects are disastrous!. And this is with me taking it only twice a week! 1. Irregular heart beat 2. Stiff painful knees 3. Extremely sore, tender feet 4. Hair loss 5. Blurred vision/ dry eyes 6. Insomnia 7. Swollen legs and feet Podiatrist was alarmed at my swollen feet & ankles. He immediately recommended tests/MRI to find out why. Heart/vein problems were suspected. Conclusion- arthritis. Nope- I discontinued Zegerid and ALL of the above problems are gone, most within 10 days. Baking soda is also a culprit. Solution for GERD? small meals w/out grease or cooked tomatoes(for me). Small adjustment for so much relief! I FEEL SO MUCH BETTER! I now RESEARCH ALL MEDS!”

1 / 10
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christru22 · Taken for less than 1 month November 12, 2018

Zegerid (omeprazole / sodium bicarbonate): “It's the same exact thing as prilosec or nexium, it works no different. The only difference is the sodium bicarbonate. Which is basically like taking a medicine similar to tums or alka zelter with your omeprazole. Don't be fooled it's all in your head. The extra couple of dollars is worth. In fact it's been proven that zegerid works no faster than prilosec, which has the same active ingredient.”

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T.L.G. November 8, 2015

Zegerid (omeprazole / sodium bicarbonate): “My doctor recommended this product for my acid reflux. I took 2 pills twice daily for about 6 days and was super disappointed in this product, not only did this medicine not help at all I feel like it made it worst. I would. It recommend this product from my experience but I know everyone's bodies are different so maybe it works for others.”

1 / 10
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Robyn75 · Taken for 5 to 10 years February 14, 2016

“I was diagnosed with GERD and erosive esophagitis after scope exploration to my stomach. Before being preceribed Zegerid 40 mg once daily, my life had went from active and full of exercise to miserable, constantly being sick, and not being able to keep anything down. I even stopped taking all vitamins and other medications because the thought of having anything on my stomach made me cringe. At one point I lost 20 pounds in about 3 weeks because I was not able to eat. Fast forward after testing I started Zegerid and it has literally changed my life. Keep in mind you HAVE to take it as directed though, on an empty stomach with a FULL glass of WATER, and don't eat or drink anything except water for an hour. Otherwise it will not work.”

10 / 10
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Anonymous March 12, 2008

Zegerid (omeprazole / sodium bicarbonate): “expensive”

10 / 10
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mrsjupiter555 · Taken for 6 months to 1 year October 24, 2012

Zegerid OTC (omeprazole / sodium bicarbonate): “It worked really fast, and as soon as the 14 day treatment was over the symptoms came back immediately despite changing my diet, exercise, etc. ”

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Anonymous · Taken for less than 1 month August 24, 2017

Zegerid (omeprazole / sodium bicarbonate): “This med gives me the best relief.”

8 / 10
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oliviarose21 January 22, 2015

“This worked better than the Ranitidine and almost worked completely, most days I have had no problems on this.”

9 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.