Pamelor and Weight Gain: What Users Say

• bir...
• October 17, 2010

For Migraine Prevention "I've suffered from migraines for 14 years and have taken numerous medications for prevention including Topamax. Topamax caused MANY bad, undetermined health issues. My Internal Medicine physician took me off Topamax and put me on 25 mg of Nortriptyline for migraine prevention. Almost immediately, I had relief from migraines, had clarity of mind even better than ever before, had a great attitude. I felt 'normal' for the first time in my life. This medication caused noticeable urinary retention, constipation, and increased appetite which caused weight gain. Due to weight gain, I was changed to Pristiq. Migraines have returned. I intend to ask to be put back on Nortriptyline and will have to alter diet and exercise."

• Suz...
• Taken for 6 months to 1 year
• September 4, 2018

For Depression "25 years ago. I took Pamelor for postpartum depression. It worked for the depression but had to stop taking because my stools became hard as rocks and were difficult to pass. I have had irritable bowel syndrome since as a result. I also gained about 40 pounds, and no matter how much I diet or exercise, I cannot lose the weight."

• Sil...
• Taken for 1 to 6 months
• March 16, 2016

For Depression "Nortriptyline isn't a very good medication for chronic headaches. My neurologist put me on 25 mg, 2 tabs at bedtime. It's supposed to make you sleepy, however, it's quite the opposite. It keeps you awake and makes you very irritable, and you still have a headache and causes weight gain. Medication, especially."