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Pamelor for Depression User Reviews

Pamelor has an average rating of 4.4 out of 10 from a total of 11 reviews for the treatment of Depression. 36% of reviewers reported a positive experience, while 64% reported a negative experience.

Pamelor rating summary

4.4 average rating out of 10.
11 ratings from 12 user reviews.

Compare all 182 medications used in the treatment of Depression.

10
18%
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18%
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9%
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27%
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Reviews for Pamelor

  • Vio...
  • Taken for 1 to 2 years
  • February 18, 2020

"I had been taking Trintellix for a couple years with success until eventually my anxiety/depression started to creep back. My doctor added 75 mg of nortriptyline every day and I swear I felt major relief in just 3 days. I have been on the Trintellix/Pamelor combo now for over a year. No side effects, and the Pamelor is cheap. As an added bonus, I have chronic hip pain due to bursitis and the pain has almost completely gone away. I am so thankful for this medicine, it has truly helped me."

10 / 10
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80 Report
  • RLZ...
  • September 13, 2014

"My neurologist prescribed Nortriptyline for Neuropathy. It did not help much for that condition. However, at the time, I was suffering from severe depression due to having to place my husband in a nursing home. The medication did wonders for me and I have been a daily user since that time."

8 / 10
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122 Report
  • Nee...
  • Taken for 2 to 5 years
  • March 12, 2023

"I have to give this drug the best review possible. No exaggerating, this medicine saved my life and helped me to learn about how much I don't know about depression, and the self-medication I resorted to was no longer needed. This self-medication that was destroying my life was no longer needed or desired. It helped me to understand that's what I was doing because of mental health struggles and that I was deserving of a better life. All I can say is thank you!!"

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31 Report

Frequently asked questions

  • Che...
  • Taken for less than 1 month
  • September 26, 2020

"I landed on the ER twice because of this medication, Pamelor. I never felt so sick in my entire life. I thought I was dying. It took me more than a week to get it out of my system. I was agitated, my heart racing at 150 per hour. Horrible experience."

1 / 10
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36 Report
  • Ned...
  • Taken for 2 to 5 years
  • July 30, 2020

"I was 13 years old when I started taking Pamelor. My doctor and mother decided to put me on this medicine. I had a very bad experience with these pills. Whenever I had an episode, they would up the dose. I started at a 25 mg tablet every morning, within the year, I was taking 5 25 mg tablets a day. Because of this, I missed out on a lot of things. I was wandering around so much that I was getting lost, didn't know who I was, or where I was going, or where I was supposed to be. I was just blah. Stuck in my thoughts, and I hated every minute of it. But it was not my choice. I have a nerve problem to this day, sometimes I shake so bad that I drop anything in my hands. It's very hard to eat soup or drink coffee when I spill it all over myself. When I turned 18, it then was my choice, and I stopped taking them altogether. A lot of my childhood was missed because of the pills, but on the flip side, I didn't get beat for having an episode as much as I did when I wasn't taking them."

2 / 10
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34 Report

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  • Suz...
  • Taken for 6 months to 1 year
  • September 4, 2018

"25 years ago. I took Pamelor for postpartum depression. It worked for the depression but had to stop taking because my stools became hard as rocks and were difficult to pass. I have had irritable bowel syndrome since as a result. I also gained about 40 pounds, and no matter how much I diet or exercise, I cannot lose the weight."

2 / 10
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34 Report
  • the...
  • Taken for less than 1 month
  • January 8, 2017

"I was tried on this for major depression. After 2 weeks on 50 mg per night, I couldn't handle it anymore. I ended up going to the ER because my heart was racing. I was at 125/130 beats per minute. I'd only been getting a few hours of sleep each night in those 2 weeks, and experienced the heart racing, brain short circuits, insomnia, anxiety, severe constipation, extreme thirst, and an overall feeling of disconnect from aliveness. As a teenager, I took Doxepin and Elavil too, and they were slightly better, but not much. These TCAs should be a last resort, like Thorazine and Lithium. Seroquel is much better. Good luck to my fellow sufferers!"

1 / 10
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31 Report
  • Sil...
  • Taken for 1 to 6 months
  • March 16, 2016

"Nortriptyline isn't a very good medication for chronic headaches. My neurologist put me on 25 mg, 2 tabs at bedtime. It's supposed to make you sleepy, however, it's quite the opposite. It keeps you awake and makes you very irritable, and you still have a headache and causes weight gain. Medication, especially."

3 / 10
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29 Report
  • DDD...
  • Taken for 1 to 6 months
  • May 21, 2015

"I was switched from amitriptyline to nortriptyline and noticed an immediate improvement the following morning. I'm sold."

8 / 10
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64 Report
  • lil...
  • Taken for 1 to 2 years
  • May 30, 2018

"Pamelor takes a solid 2 months to start working. The best medication ever. Less than 1 dollar for a pack of 100 tablets of 25 mg where I live."

10 / 10
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48 Report
  • Kay...
  • Taken for less than 1 month
  • July 5, 2018

"After taking Pamelor for one week, I had to stop. I had horrible nightmares that stopped after I stopped that medicine. I still shake thinking about the nightmares."

1 / 10
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30 Report
  • jos...
  • Taken for less than 1 month
  • February 24, 2019

"Gave me bad indigestion and nightmares!!!"

2 / 10
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14 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.