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User Reviews for Nefazodone to treat Major Depressive Disorder

Nefazodone has an average rating of 9.4 out of 10 from a total of 18 ratings for the treatment of Major Depressive Disorder. 94% of reviewers reported a positive effect, while 6% reported a negative effect.

Nefazodone Rating Summary

9.4/10 average rating

18 ratings from 19 user reviews.

Compare all 54 medications used in the treatment of Major Depressive Disorder.

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Reviews for Nefazodone

Erna · Taken for 1 to 6 months April 4, 2021

“There is this company tcichemicals(Tokyo chemical industry) they do show the drug on their database I am enquiring in that direction whether they can supply nefazodone . Hope that they do for all of us.”

10 / 10
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Nefazodone Man October 16, 2020

“Hi to the user that just posted a little bit ago, Today is October 16th 2020 --- I too call Teva once a week, I have been on it 24 years in 2021 --- I am keeping the faith they make more, they have not said discontinued yet, I call the FDA also... BUT Teva cannot give any date at all when it may be released again, which sucks for us, but they still have not said it is gonna be discontinued.... Hopefully the reason that there is a shortage is their COVID shutdowns, are what is the cause of this disruption from last March, April around the world, and this will get resolved quickly... We are not numbers, or $$$ signs, we are people with a DISEASE and for some of us long term users, this has been a LIFESAVER to improve our quality of life that some of us did NOT have prior till getting on this Wonder Drug for us... I know it is not popular, not a 1st or 2nd Choice, BUT for some of us, it has been a Miracle Wonder Drug.....”

10 / 10
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Rose · Taken for 10 years or more September 4, 2021

“I was on Nefazodone for over 20 year and it shaped my life, It helped me become myself by controlling my symptoms without any side effects. Without out it my life is falling apart. My last dose was 11/5/2020. I'm flooded with depression, anxiety is wrapped around me... squeezing, squeezing. I can't breath. I've put on a lot of weight. My clothes don't fit. I don't go out, can't think, play guitar, or write. I keep trying other meds. No luck. Now I'm on Fetzima. Maybe it will help. I love my life, I miss myself. I called Teva and was told Nefazodone would be back. Teva wants money, it's logical that they would want it back on the market. I'm 64. Being older wasn't supposed to be so horrible. Until then I have prayer. God doesn't care if I'm fat. And I have all of your to talk to. Thank you.”

10 / 10
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Laura March 16, 2021

“I am 66 years old and have been on Nefazodone for 30 years. I had tried many other medications before nefazodone that did not work or the side effects were outweighing the purpose of the drug. My doctor prescribed Nefazodone and I have been right with the world since. It worked beautifully, with no liver issues and no side effects. Then the hammer dropped. The pharmacy called and told me Nefazodone was no longer available. It felt like the rug got pulled out from under me. With the pandemic and isolating, this is not the time to discontinue this drug! I feel my quality of life will not be the same and I am afraid of what the impending depression will do to me. I feel like it's a farewell to what I've known and loved these last 30 years. I am praying this is only temporary. Teva is the only company that makes this medication. For those who depend on this medication, write to them and plead with them to bring it back.”

10 / 10
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CG · Taken for 6 months to 1 year October 23, 2020

“After 20 years of depression, doctors and pharmaceuticals, I finally found Nefazodone. I’ve felt better in the last nine months than I have in years!!! Even through the pandemic, my anxiety has been tolerable...until today. My pharmacy tells me the drug has been discontinued!!! I hope the stuffed suits who made that decision have some idea of what they’ve done to people who rely on this medication!!! I’ll sign this Panicked and Disappointed”

10 / 10
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Linny July 22, 2021

“I have been on nefazadone since 1996. I cannot find another antidepressant that lifts my mood without drowsiness or blurred vision. I’ve tried remeron and trazadone. Please make nefazadone available to patients who are suffering without it.”

10 / 10
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venkman17 · Taken for 5 to 10 years December 31, 2020

“Hey guys, I just wanted to give you an update. Many of the reviews informing us that nefazodone has temporarily been discontinued, is slightly incorrect. Teva Pharmaceuticals has temporarily stopped making it due to a shortage of its main ingredient. That does not mean it's discontinued as of yet. In the meantime, those of you who need to wean off of it so that you can successfully get on to a new antidepressant, please call around to pharmacies across your city. Many pharmacies other than the one that you currently use, have supplies of it still left in their inventory. I managed to find many pharmacies around where I live, and have been able to get an another months supply so I can wean myself off. Good luck to all of you all, and I pray and hope that they will soon restart manufacturing. I hope this helps”

10 / 10
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tina · Taken for 10 years or more December 11, 2020

“All I can say is that this medication Nefazodone even when it was Serzone took away my depression and anxiety which was a monster. Been on it for 20 years. If this med goes off the market, my life is over. That's all I have to say.”

10 / 10
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Anonymous December 4, 2020

“Nefazodone pulled me out of a 5 year depressive episode where I could not function. Since being on Nefazodone I haven't felt better in my life !!!! I am so stable... Now it's discontinued !!!!!! I am so upset and worried. I can't believe they could do this to people.”

10 / 10
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Threse October 29, 2015

“I have been dealing with major depression and terrible anxiety for the last 40 years. I had tried at least 6 different antidepressants, none of them really helped until one doctor put me on the nefazodone. Within 3 weeks what a difference, the relief, the sadness the anxiety, the panic feeling all lifted. This medicine pretty much saved my life. To this day I still take it. It's a wonderful medicine. I hope they never take this off the market.”

10 / 10
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puccini4me June 24, 2021

“If unable to get this drug from Teva I can tell you my experience how help get it back on market. This happened with Teva clonazepam couple yrs ago. I was on a blog & found out people called Teva directly, asking to please put it back on the market.....our calls made a difference - took a couple months but it worked! Now my Dr writes "Teva brand only" on my Rx Try it.....make several calls/day...it works! currently not taking nefazodone but here to check it out for my depression.”

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sad · Taken for 10 years or more July 10, 2021

“I took Serzone/nefazodone for ~20 years along with Effexor. I am still taking the Effexor but have been without nefazodone for 2 months. I was able to titrate off for a month until reaching zero 2 months ago. I feel horrible! I do not know who I am anymore. I had made so much progress in the last 20 years... through therapy, 12 step programs, and spiritually! Now, without nefazodone, I feel like I have lost any progress I had made! I don't think the same way. I don't feel like the same person. I've lost my self. I have a cold heart. This is no way to live.”

10 / 10
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Nana of three November 30, 2020

“I have had depression and anxiety issues for 31 years, SSRIs do not work for me. My doctor had put me on Serzone when it first came out years ago and it was the only medication that truly worked for me. I am also on two other Atypical antidepressants to combat other issues I have with sleep and mood. The fact that I can no longer receive Nefazodone has really affected me profoundly and not being able to be on it is a shock to my system as I was not able to wean myself off of it as one should do. In my research I have found that Teva is missing a compound to manufacture it. No answer in regard if it will be available in the near future is disheartening since I would like to feel normal again. Now I am at square one again and have to see a psychiatrist, this will be my third so he can prescribe some other medication that I hope will work as well as Nefazodone has for the last 26 years.”

10 / 10
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JesyRay · Taken for 1 to 6 months November 20, 2016

“I've been taking antidepressants since 1999. I've taken most every SSRI plus many others that never worked long. I have MDD & GAD. I've never taken any med that actually worked. Celexa lasted a/b 2 yrs. then stopped. I needed help earlier this year, admitted myself. My Dr played with my med regimen for a bit but there's always trial & error w/ these meds. He kept asking me a/b all these different meds to see if I tried before. I had. He finally told me a/b Nefazodone & gave me it's full hx. I got that weed "high" for a few days (inc. fatigue nausea blurred vision). Ithe went away after a week or 2 but I also explained to Dr the only word I could use for it was ecstasy. It made me feel so much better. No more side effects either!”

10 / 10
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Bonniewest · Taken for 5 to 10 years January 6, 2020

“I started taking Nefadazone in January 2000 and continued taking it until 2015 when I was told that it had been taken off of the market. I had to drive about 25 miles to a pharmacy. So my new Dr. prescribed an SSRI called Celexa. I have been on the lowest dose possible and still gained about 30 lbs and no matter what I do, I cannot get my weight to budge. Each time that I go to the Dr’s office my weight is up again even if I stick to 1200 calories a day. I am going to be going back to Nefadazone once I see my Dr in February. I will take it along with Wellbutrin. I started that regimen 20 years ago and felt the best that I had felt in years! I believe that I will feel better once again!”

10 / 10
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Sal · Taken for 10 years or more December 22, 2020

“Nefazodone works best for me after trying multiple antidepressants and failing. I have depression with anxiety and panic attacks as well maniac depressive disorder, ADHD. Together with other meds keeps me going last 20+ years. I tried to stop taking it but had super hard withdrawal, have to remain on it even-though my insurance does not cover it!”

10 / 10
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Santa Rosa · Taken for 1 to 6 months July 3, 2019

“I was prescribed Serzone in 1999 at the onset of major clinical depression. I was under care of my GP and a psychologist. I experienced hallucinations and heard voices. My psychologist was worried about the drug, especially when I told her about the day I was being told to fly with the birds and as a blast of cold wind blew me out of trance, found I'd climbed my balcony and was about to jump off. I ran indoors and locked myself in. I was referred to a psychiatrist who immediately took me off Serzone and started me on Effexor XR. I researched Serzone on the internet and saw many legal class actions against the drug company on the grounds it causes suicidal ideation in some patients. Effexor, like all psychiatric drugs, comes with its own drawbacks, but has been safer and more effective for me. I continue to be on anti depressant Effexor medication to this day 20 years' later. Major depression is an insidious disorder.”

1 / 10
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Mistifalx · Taken for 1 to 6 months March 4, 2015

Serzone (nefazodone): “Minimal side effects. Last resort after many years on other antidepressants that I couldn't tolerate the side effects with or just plain didn't work”

9 / 10
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H · Taken for 5 to 10 years December 18, 2020

“Best antidepressant I ever used. Also helped me sleep earlier when no other drugs worked as well to treat my Circadian Rhythm Sleep Disorder (Delayed Sleep Phase Disorder).”

10 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.

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