Naltrexone and Tiredness: What Users Say (Page 2)

• met...
• Taken for less than 1 month
• May 2, 2017

For Alcohol Use Disorder "First day on 25 mg, feeling tired, sometimes cold, hot, but NO cravings. Not particularly hungry either. Just reading that this drug should not be taken until a week after alcohol is out of the system. From what I am reading here, people just drank until they started taking naltrexone. True? Good info here for beginners, thank you all for sharing, very helpful. I believe this is going to work for me, so I can get back on track with my life."

• Kat...
• Taken for 1 to 2 years
• February 12, 2022

For Fibromyalgia "Unusual tiredness that did not come on until the past 6 months that I could barely get out of bed. Motivation: gone. This will slowly sap you dry till you're so weary you don't know what from because it used to work. Slick drug, be careful as it brings on chronic fatigue."

• Tif...
• Taken for less than 1 month
• May 19, 2023

For Alcohol Use Disorder "My psychiatrist prescribed it because I've been having trouble with my alcohol intake since the pandemic. I take it with Latuda, Zoloft, and buspirone. This stuff works! I don't drink during the day or when I am triggered by stressful moments. I can also turn down drinks when I go out. It almost feels too good to be true. The worst side effect for me is tiredness. I take it at night, but still feel the effects throughout the day. Also, do not drink with this medicine. I went to a party and drank socially ONCE since being on the meds and I threw up the next day; my stomach was in shambles. My partner also noticed that I had been slimming down. After a Google search, I see naltrexone aids some people in weight loss, which I think is kind of cool."

• Igu...
• Taken for 1 to 2 years
• September 13, 2019

For Alcohol Use Disorder "I took naltrexone for more than a year. The cravings subsided for about 30 days, and then I started drinking. It did not lessen the effects of alcohol or the crack. I'm nervous about taking Vivitrol because of the side effects, especially the lethargy, cramps, and loss of appetite. I've been drinking for more than 40 years, and I think I could die from just exhaustion."

• Tbi...
• Taken for 1 to 6 months
• August 22, 2018

Naltrexone for Opioid Use Disorder "Was on Suboxone for years and tampered with it to be able to use heroin consistently. Have been off heroin for 10 months and Suboxone for 6. Got onto Vivitrol 6 months ago, and at first felt like garbage. Thought it was the Vivitrol because I always felt fine taking Suboxone, but in reality, it was my body adjusting to being without an opioid. After 2 months, I started feeling better. Forcing myself to exercise has helped a ton. Now when I get my Vivitrol shot, I feel a little lethargic and unmotivated for the first few days, but it goes away. Honestly, worth the annoyance for saving a life."

• Far...
• Taken for less than 1 month
• February 15, 2018

Naltrexone for Alcohol Use Disorder "Just started and noticed sleepiness and lethargy. I am also taking 5 mg of Valium 2x a day to wean off of Ativan. I think that, in conjunction with other meds, the shot is causing the effects. I take HBP medication, which itself causes drowsiness, so I'm hopeful that I will be able to adjust all of my meds to accommodate staying off the alcohol. Has anyone had side effects the first time/first few days similar to this? Extreme sleepiness/lethargy?"

• Mid...
• Taken for less than 1 month
• January 27, 2018

For Alcohol Use Disorder "Day 6 and totally amazed. My cravings are almost non-existent. I do feel totally exhausted about 2 hours after taking it, so I need to change to bedtime. I have had a strange side effect though that I have not heard anyone else mention. When I stand up after sitting a while, the muscles in my legs (mainly quads) tense up so strongly that I literally cannot move for 2-3 seconds. Has anyone else experienced this?"

• Jen...
• Taken for less than 1 month
• July 24, 2017

For Alcohol Use Disorder "I have been taking it for three days, and I have no cravings, but I haven't been able to keep any food or fluid down. I've been really tired. The first night, I had hallucinations and was hearing voices."

• mor...
• July 29, 2016

For Alcohol Use Disorder "I started taking naltrexone about 3 days ago. 6 1/2 weeks ago, I began detox/withdrawal in an inpatient setting for anorexia. I could have never gone from a fifth of vodka a day for 2+ years without this medical intervention. After detoxing with Librium, I started Campral (still in inpatient with no access to alcohol). I started naltrexone in addition to Campral (and other meds for bipolar, anxiety, depression) 3 days ago. I returned home today, and I'm sad to admit I chugged about 1/4 bottle, not remembering I was on naltrexone. I recognize that I'm quite heavy-headed, but I feel bored and lethargic rather than uninhibited, as I normally would. I am so happy to have access to a drug to take away the influence alcohol had on my life."

• Jim...
• Taken for less than 1 month
• July 7, 2019

For Alcohol Use Disorder "I took one 50 mg tablet. A short time later, I became tense and irritable. The next day, very tired, irritable, dizzy, nauseous, unable to cope with even the slightest noises or interactions with people. Everything upset me. I did stop drinking because the feeling reminded me of a terrible hangover. Hope it goes away soon. It's been 2 days."

• Mor...
• May 31, 2017

For Alcohol Use Disorder "On 50 mg for 5 days, taking it in the morning. I'm 50 years old, in and out of rehab, my last 3 walked out. I'm presently attending pretreatment for intensive outpatient. Want my life back, alcohol has been a way for me to deal with problems. The 1st day was bad: very achy muscles, joint pain, very tired, bad headaches, want to sleep, anxious, nervous. Too many side effects to even think of drinking. The 5th day was worse than the 1st day. Wondering if the injection is any better than the daily dose."

• Aro...
• Taken for less than 1 month
• August 31, 2021

Naltrexone for Alcohol Use Disorder "On day 5, I had 1 beer the other day, and I tried to drink a second but couldn't stomach it. Granted, I don't love beer, but the desire was not strong to want to get drunk. BUT, it has taken a toll on my sex drive. I just don't feel the need to cum. I hope this doesn't continue and affect my relationships. Also, I am a wee lethargic, but I can battle that for now. YEAH, THE SEX DRIVE THING SUCKS. BTW, I take the VIVITROL pills."

• Ray...
• February 28, 2018

For Alcohol Use Disorder "Started this for weight loss. I'm already on 450 mg of Bupropion, so just added Naltrexone 50 mg. I cut the pills in half and take 25 mg a day. It's cheap. 25 mg made me tired at first and a bit depressed, but that seems to be leveling out. I had a few beers a couple nights ago, and it actually improved the feeling. Anymore, I lose interest in drinking after 2 or 3 beers. I'm a long-time sufferer of OCD and Dysthymia. I self-medicated for years. Naltrexone doesn't help the OCD, but it seems to help with the other issues. Taking the two medications creates the prescription weight loss drug 'Contrave.' The optimum dose of Contrave is 360 mg Bupropion and 32 mg Naltrexone."

• pat...
• Taken for less than 1 month
• March 15, 2021

For Opioid Use Disorder "I've just started with said drug, and day 1 is incredibly hard. I'm tired, cramps, and diarrhea. However, that's why I came here, to look at all y'all's experiences. Writing about this alone is helping. However, most afflictions being cured are for alcohol dependence, and I've been on options for over 12 years and have decided to take another step (3rd) to quit. Hoping this is the one. If okay, I will post regularly to give a proper insight into my journey. Couldn't sleep last night, generally really tired and weak, serious cramps and diarrhea are currently after taking 25 mg. A luta continua. Thanks for accommodating me. All the best, everybody."