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User Reviews for Morphine Sulfate ER to treat Chronic Pain

Morphine Sulfate ER has an average rating of 6.5 out of 10 from a total of 19 ratings for the treatment of Chronic Pain. 53% of reviewers reported a positive effect, while 26% reported a negative effect.

Morphine Sulfate ER Rating Summary

6.5/10 average rating

19 ratings from 21 user reviews.

Compare all 48 medications used in the treatment of Chronic Pain.

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Reviews for Morphine Sulfate ER

Bob · Taken for less than 1 month September 30, 2019

“Due to the Opioid problem the VA switched me to Morphine SO4 15 mg three times a day for chronic spinal pain. It was effective for about 5 days. After that, it seems like every pill has a different release pattern. Sometimes I get no relief at all. Why is there so much problem with the release portion and why does somebody not fix it. This is the 21st century. If the VA wants people off Oxycodone, there needs to be a working alternative available so pain sufferers get pain relief.”

3 / 10
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JJ June 28, 2020

“I started working construction for my family's company when I was 12, just in the summer and by 18 full time. I wrecked my back by the time I was 30, had my first fusion before I was 35. Now I still suffer chronic pain, severe degenerative disc disease, and I've developed arthritis in my shoulders. My first pain doctor was horrible, at one point I was taking so much MSContin a day, I was a zombie! Once I got away from him, spent six months working my way off MSContin, I toughed it out for almost two years. When I couldn't take it anymore and was on the verge of suicide from the pain, I went and found a good pain doctor. Over two years I slowly went back on MsCon, now I take 45mg three times a day. He saved my life and gave me back some quality of life, more than I ever thought I would have. I've been at the same dose for the past ten years. I've seen both the good and the bad of this med and have no reservations about taking it, my life would suck without it!!”

10 / 10
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CARI · Taken for 10 years or more July 11, 2021

“I am 55 & have been on this long acting medication for decades. It keeps my overall pain on the level but doesn't seem to conquer the severe bone pain. I have other med for breakthrough pain. I have had RSD for almost 30 years now , had Endo as well as Fibro, DDD, Spinal Stenosis, Post-Lyme Arthritis and Adhesive Arachnoiditis from the 14 years of constant Epidural Injections. One of which went very badly in 2007. Morphine ER saved my life. When the Drs. decided to force taper me off both of my Rx Opioids in 2018, due to the totally misread 2016 CDC Guidelines, I simply wanted for my journey to end. The pain was worse than I could ever explain & I would only get 1 to 2 hrs. of sleep. I finally found a Doctor in January 2020 and while, due to the overall stricter prescribing standards, my Dr. could only prescribe a little bit each month until I finally got up to my dose of 60mg, 3 x daily. This medicine is a Godsend for my quality of living.”

7 / 10
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96chanz · Taken for 2 to 5 years July 1, 2018

“As a 21 Year old who has been dealing w/ Chronic Pain since the age of 11. I've been on almost every opiate (Fentanyl, Oxymorphone, Codeine, Methadone, etc) I've found Morphine 30mg every 8 hrs for to be by far the MOST effective out of all opiates. I am rx'd Roxicodone 30mgs 3 times a day for breakthrough pain but I rarely take it as I find it only gives me a 'buzz' & lasts 1-2 hours as far as pain relief is concerned. I am also prescribed Klonopin 1mg t.i.d. prn for PTSD, GAD. Also Adderall 20mg (90) for ADD/Social Anxiety. This combo I've found to be effective for all of my conditions and I truly feel this is the best method for my chronic pain. Yoga helps as well I've found. I suffer from Severe Sciatica, Gallbladder Calculus with acute cholecystitis w/ obstruction, Severe Spondylolisthesis, Severe Thoracic and lumbosacral neuritis, Chronic Pain Syndrome, Scoliosis w/ spinal stenosis, inguinal hernia w/ obstruction, degenerative disc disease. Bilary obstruction, etc.”

10 / 10
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Don't be Afraid! December 9, 2017

“Many years ago, I chose medication over surgery to treat severe, chronic pain. Although dependency on pain medication has it's own problems, I still think it was a good choice. I have had almost 20 productive years that I would not otherwise have had. I have learned two things in those years. First, if you are taking Morphine ER, try to arrange your schedule in such a way that you have an hour or two to nap after you take your meds. This medication is more effective if you are sleeping or at rest as it takes effect. Second, avoid oxycodone or oxycontin [time-release oxycodone]. That medication rapidly looses effectiveness and becomes unreliable. For me, the best overall pain med has been Morphine ER. Hope this helps, and God bless.”

8 / 10
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Jewels14 · Taken for 6 months to 1 year March 17, 2014

“Morphine Sulfate ER 15 mg. I have been using this for approximately 6 months. I find that many of the side effects listed have become apparent to me. I do experience: shakiness, constipation, elevated liver enzymes, difficulty urinating, uncontrollable sleepiness, blurred vision, sensitivity to bright lights at nighttime, including some indoor lighting. In addition, I suffer from stomach pain, feel lethargic at times, memory loss, lack of desire to socialize, depression, and other minor events that I did not have prior to taking morphine.”

8 / 10
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Phil Atio January 17, 2018

“Been on various opiates since my mid 20s and now I'm mid 50s. If I could choose what ever medicine I wanted for pain relief I would choose Morphine as it is the smoothest, longest lasting and consistent narcotic. Comes on slowly and has long legs. Avoid Oxy as it hits very quickly and falls off often randomly but always sooner. Morphine ER last a good 8 to 12 hrs. Worst side effect long term for me is constipation and occasional hot flashes. Together with Gabapentin and a muscle relaxer mask my sever back injury enough that I can avoid a major risky surgery.”

8 / 10
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Frequently asked questions

Anonymous February 20, 2018

“I have been diagnosed with MS for 20 yrs. And just recently had back surgery I'm taking 30 mg morhine sulfate ER along with 10mg norcos for breakthrough pain. I'm 4 weeks post op and still having severe lower back pain and the morphine does not seem to be touching the pain which makes me take more breakthrough pain has anybody else had issues with morphine not helping?”

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Rosie44 May 21, 2015

“Have been taking Er 120mgs 3x a day, with 60mg. For break through pain. I suffer from chronic spinal stenosis with acachnoditis. That being a progressive disorder. After many different Doctors rx not helping' went to pain management clinic. I was inpatient for 4-5 days till they finally found right drug & most important dose. I Do take 60-90mg for breakthrough pain. It works so well. Bless those Dr's that took the time & effort to find answers. I am on same dose for awhile now. The only side effect is bad constipation. I use a stool softener . What a relief to finally have a decent quality of life finally.”

9 / 10
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Sro March 5, 2018

“I have been in pain for 30 years from My spinal cord is being over stretched since age 13. During my growth stage when your spinal cord lifts away from your lower back. I’m have spinalbifita acolta spinal canal does not make a full circle around your spinal cord it makes a C instead. A fatty lipoma grew through the C and attach it’s self into my spinal cord and tethered it to my bones and is cutting off blood flow to my nerves which is causing nerve damage and pain. I have been to more than 20 pain specialist there is no way to operate on it. So right now I’m on 6 Oxycodone 10mg , 3 morphine sulf ER75mg a day and 2 fentinayl patches 100 mcg/hr every 2 days Basically I’m on a huge amount of pain meds all narcotics a day. I’m now 44 I still have a huge amount of pain. What I have learned about all pain meds is you build up a tolerance to all of them after a while.There is no magic pill like morphine sulf ER.If you have enough pain nothing works good enough and you have to make it work.”

2 / 10
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LSCDC October 12, 2016

“I have chronic back pain for 23 years following a fall down a flight of stairs. I ruptured 3 discs and fractured various vertebral areas in my lumbar and thoracic spine. I also have Chronic Lyme Disease, Brucellosis and I have developed Fibromyalgia and Chronic Regional Pain Syndrome in both lower extremities. I have various types of paresthesia from burning to lancing. I have been on many types of Schedule II opioid pain medications from Fentanyl, Morphine, Hydromorphone, Oxycodone, Hydrocodone and Methadone. The best relief & safest medication has been the Morphine Sulfate Extended-release 200mg every 12 hours with 30 mg Oxycodone every 4 hours for breakthrough pain. I just wish it was less expensive since I do not have insurance”

10 / 10
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LilDebbie cakes · Taken for 5 to 10 years September 4, 2017

“I have tried several different pain meds.I had 2 discs in my neck replaced in 2008 and have a neck fusion. I also have severe and chronic pain. It's unbearable at times. I take 60mg ER one in morning and one at night. It's the only thing that lets me function and xanax 2mg relaxes the muscles in my neck and back. I find it works better if I take 1 and lie down for about 20 minutes to let it work better then I'm good til evening. I wouldn't be able to get out of bed without them. It really takes my pain away like nothing else ever. I've been on it for about 7-8years.”

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winipu4 September 24, 2017

“ZYDUS is the WORST brand MS ER 60 I have EVER been given in over 15 years!! It only works 8 hours instead of the 12 out is supposed to. No pharmacy should be using this. I have six large screws in my spine; L3-5, and suffer chronic and debilitating pain.I have never been given a generic that didn't work -until now. STAY FAR AWAY FROM ZYDUS !!!”

1 / 10
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Kevin the sciatic man · Taken for 6 months to 1 year January 17, 2016

“Kind of useless on the pain I'm in, was on it for 7 months, 4x a day 2x30mg ER and 2x30mg IR and I was still in pain and coming off it was a process. I never once took it other than prescribed and there is no doubt in my mind I was physically addicted to it. I weaned myself off for months to the point I was taking 1/4 a pill right when I laid down just so it did not feel like my skin was crawling as I tried to sleep. This is an addictive and useless pill for sciatica issues in my experience.”

3 / 10
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kimmster607 · Taken for less than 1 month June 16, 2015

“15mg 3x a day ER. I've been trying to find the right medication to treat fibromyalgia pain. I've experienced nearly every side effect, worst being respiratory problems and weight gain. My attitude has been poor and I'm completely miserable. It's increased my depression. For all the horrible side effects I've experienced, it doesn't seem worth it to stay on the medication for MINOR pain relief. The same has happened to me with Lyrica (neurontin with a prettier name) and tramadol ER. Morphine is by far the worst. I gave it 2 weeks but I can't take anymore of the nausea and illness this medication has caused. I took a morning dose today and feel ill, as usual. I can't wait to flush this garbage from my system.”

1 / 10
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Copierguy1961 · Taken for 1 to 6 months February 20, 2016

“I was on 40mg of Methadone four times a day for 5 years and it worked fairly well to control my pain. I have have back surgery at L5/S1 and have disc degenerative disease. Due to a change in insurance I have had to change to a different med. Now I am on 90mg of Morphine Sulphate ER. This does not seem to be helping close to what the Methadone was. I need help to find a medication that will help. Both my pain specialist and I thought this would do the trick but even with steroid injections I am still in massive pain.”

5 / 10
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sillyworm June 11, 2015

“I have been taking Vicodin for near 20 years now due to chronic pain in my lower back and chronic pain & burning in my shoulders from Factory work.I have been on six 7.5 Vicoprofens for a few years now. That amount works fine if I just sit around all day. If I want to take long hikes, Lift or move furniture, do extensive house cleaning then 6 is NOT enough and I was using 7 or 8 a day. Doctor wanted me to try Morphine ER 15MGs..2 a day and try to get down to 3 Vs a day. A month into this trial period and I'm not liking the Morphine ER (and I've tried 300MG Tramadols & Butrans Patches) The morphine just leaves me feeling sleepy, it just takes the edge off and like so many other medicines ,I have FLU like symptoms. If I had 10 mg pills that would work.”

5 / 10
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Anonymous · Taken for less than 1 month December 24, 2016

“I've tried MS Contin a few times over the years and finally given up. What I really liked was good pain control without the euphoria or crash of IR products like oxycodone. What I didn't like was, after a few weeks, developing hallucinations and delusions that were so... real. I actually listed it as an allergy on my med records. Others tolerate it well. I'm not them though. Morphine derivatives like Dilaudid cause me no problems. It sucks, and is terrifying, to wake up convinced the bed is covered in spiders, to the point of seeing them. Not for me.”

7 / 10
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im a fool · Taken for 5 to 10 years February 5, 2016

“my breathing got very bad I wasn't told about the side affects I read about it on this site and I ask my gp why I wasn't told about the side affects and he wouldn't tell me so I may need to talk to my lawyer”

9 / 10
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Millie57 · Taken for 2 to 5 years October 17, 2014

“Yesterday was the first time using this medicine. And it works Great, I also take Lortab. I did not take any, only the Morphine Sulfate ER and it kept all my pain away for 12 hrs. Love It.”

9 / 10
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jerjer · Taken for 2 to 5 years March 6, 2013

“I have tried every pain medication there is. Morphine lasts the longest and keeps the pain tolerable then anything else.”

9 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.

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