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Toprol-XL and Insomnia: What Users Say

Insomnia: mentioned by 7 users (11.3%)

Based on user experiences from 62 Toprol-XL reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 14.5%
tiredness 14.5%
fatigue 11.3%
heart palpitations 11.3%
insomnia 11.3%
shortness of breath 11.3%
depression 6.5%
dizziness 6.5%
drowsiness 6.5%
headaches 4.8%

Reviews for Toprol-XL

Commonly mentioned side effects
  • Deb...
  • Taken for 1 to 2 years
  • June 5, 2021

For High Blood Pressure "I was on Toprol-XL and experienced many of the 41 side effects listed on the website but not included with the warning label. I experienced nausea, diarrhea, heartburn, dry mouth, drowsiness, fatigue, insomnia, anxiety, lightheadedness, cold feet & hands, shortness of breath, wheezing, fluttering heartbeat, shortness of breath with mild exertion, dizziness, loss of appetite. I went to the doctor and ER several times fearing a heart attack but was found to be in good health. No one knew what was wrong until I researched and found all my symptoms under this medication. I stopped 2 days ago and blood pressure is now normal and most symptoms have gone away and improving. It takes about 7 days to feel normal per the website. I will NEVER take this medication again. Be careful, the side effects mimic other potential health issues. See your doctor and seriously look up side effects of Toprol-XL. A very nasty medication!"

1 / 10
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  • bbj...
  • April 20, 2009

For Atrial Fibrillation "I have atrial fibrillation - beats to 180 very irregular beat, converted in 45 minutes in ER. Started me on Toprol 25 once a day. Heart rate now around 60-70, blood pressure 120/70. Side effects so far include problems sleeping, restlessness, also drowsy on and off. Only been taking this drug for a week now, perhaps the side effects will reduce in time."

7 / 10
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120 Report
  • Sca...
  • Taken for 1 to 6 months
  • April 7, 2022

For High Blood Pressure "This is an update to a post I made in October 2021. I discontinued Toprol due to nasty side effects after only 2 months of use (severe anxiety, panic attacks, severe depression, insomnia, swelling of extremities, bloat/gassy, blurred vision, icy hands/feet, arrhythmia, shortness of breath, chest vibrations). It's been 1 year and 3 months since discontinuation. I am STILL experiencing off and on arrhythmia. I've had a thorough exam and testing with 30-day monitoring from 2 different cardiologists. My heart is very healthy, no blockages, no disease. Neither cardiologist can find any reason for the persistent arrhythmia, nor will they believe me when I tell them I think the Toprol caused this long-term persistent arrhythmia. I've also had extensive endocrinology testing and nothing is coming up as a reason for this arrhythmia. NOTE: I've never in my entire life had any heart arrhythmia or palpitations UNTIL I took Toprol, and now it's a regular occurrence. This cannot be a coincidence."

1 / 10
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Frequently asked questions

  • Anonymous
  • March 11, 2008

For High Blood Pressure "I started taking Toprol XL 100mg one week ago. My blood pressure and pulse are much better. 125/75 and 75 pulse compared to 160/100 and 100 pulse. The only problem I am noticing is my sleep. I am not sleeping soundly. I toss and turn all night, something I guess I will get used to. Other than that, it is keeping me calmer, my heart is not racing nor is my head pounding. I have had high blood pressure for 12 years and tried many kinds of medications. I am hoping the new cardiologist is on the right track!"

9 / 10
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  • Anonymous
  • January 2, 2010

For High Blood Pressure "I have not liked this medication at all. I was taking 25 mg of Hydrochlorothiazide, which worked great to reduce and maintain my blood pressure, but a side effect was frequent urination, and as a teacher, that was a slight nuisance. However, with generic Toprol, I have not gotten a decent night's sleep, and my blood pressure went higher (although I halved the 25 mg pill due to the side effects). I also feel anxious and unsettled."

2 / 10
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83 Report

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  • Sca...
  • Taken for 1 to 6 months
  • October 30, 2021

For High Blood Pressure "DON'T TAKE THIS POISON!!! I was on it only 2 months. Weaned off as directed after experiencing horrible side effects (fatigue, shortness of breath, bloating/gassy, weight gain, joint pain, limb swelling, facial swelling) and went through an absolute nightmare getting off of this drug. I had severe panic attacks, anxiety attacks, depression, insomnia, arrhythmia, vagus nerve dysfunction, and chest vibrations. It has been 8 months since I discontinued this awful drug, and the arrhythmia continues on a regular basis. I never had any palpitations or arrhythmias ever in my life until I took Toprol, and now it's a daily problem. I fully regret ever taking Toprol. It was nothing but bad from the very first pill....."

1 / 10
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  • Anonymous
  • September 9, 2010

For High Blood Pressure "Took it 2 times and it gave me chest pain, nervousness, and could not sleep. Stopped taking it."

1 / 10
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70 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.