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Toprol-XL and Anxiety: What Users Say

Anxiety: mentioned by 9 users (14.5%)

Based on user experiences from 62 Toprol-XL reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 14.5%
tiredness 14.5%
fatigue 11.3%
heart palpitations 11.3%
insomnia 11.3%
shortness of breath 11.3%
depression 6.5%
dizziness 6.5%
drowsiness 6.5%
headaches 4.8%

Reviews for Toprol-XL

Commonly mentioned side effects
  • Vin...
  • Taken for 1 to 6 months
  • April 15, 2021

For High Blood Pressure "Was on Toprol XL for only 6 weeks and had to get off of it quickly. HORRIBLE anxiety/panic attacks, constant arrhythmia, tachycardia, passing out, hypoglycemia, hallucinations, nightmares, Raynaud's syndrome, etc. This drug almost finished me off. I had 13 severe panic attacks since starting it, and if I wasn't as healthy a person as I am, I am certain it would have given me a heart attack. I am now exactly 8 weeks off of it. Most of the horrible symptoms have stopped, except the arrhythmia that comes and goes. In my opinion, Toprol is a serious endocrine disrupter and should be pulled from the market. It is a very dangerous drug. Can't believe how sick I became after starting it. Screw all pills. I can control my BP with diet. I truly regret ever putting one of these poisonous pills in my mouth."

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  • Deb...
  • Taken for 1 to 2 years
  • June 5, 2021

For High Blood Pressure "I was on Toprol-XL and experienced many of the 41 side effects listed on the website but not included with the warning label. I experienced nausea, diarrhea, heartburn, dry mouth, drowsiness, fatigue, insomnia, anxiety, lightheadedness, cold feet & hands, shortness of breath, wheezing, fluttering heartbeat, shortness of breath with mild exertion, dizziness, loss of appetite. I went to the doctor and ER several times fearing a heart attack but was found to be in good health. No one knew what was wrong until I researched and found all my symptoms under this medication. I stopped 2 days ago and blood pressure is now normal and most symptoms have gone away and improving. It takes about 7 days to feel normal per the website. I will NEVER take this medication again. Be careful, the side effects mimic other potential health issues. See your doctor and seriously look up side effects of Toprol-XL. A very nasty medication!"

1 / 10
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  • Tra...
  • December 2, 2016

For High Blood Pressure "Wow! I have not been feeling well for a long time. Until Toprol XL 25mg. My head is clear. I can think straight. I don't have any anxiety. My work performance is at its greatest level. Even my sexual drive is back. I get up rested in the morning and feel no fatigue. I don't know about anyone else, but I'm glad to take this medication."

10 / 10
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Frequently asked questions

  • Dea...
  • Taken for 1 to 6 months
  • October 7, 2017

For High Blood Pressure "I had a transient ischemic attack (TIA) in March 17. I'm a 53-year-old male. Always had a higher heart rate and a family history of high blood pressure. I could actually feel the TIA coming on over a few weeks, but I'm a tough guy. Several drugs tried and failed. Lisinopril damn near killed me with a blood pressure of 175/133. Read a lot and switched to Toprol-XL, no generic!! I take 50mg at night, slow release. Feel great and few side effects. Pressures are good and heart rate is down. Sex still works and anxiety is cut in half. Good stuff. Takes a 1-2 week adjustment period. Relax and let it work."

10 / 10
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  • Sca...
  • Taken for 1 to 6 months
  • April 7, 2022

For High Blood Pressure "This is an update to a post I made in October 2021. I discontinued Toprol due to nasty side effects after only 2 months of use (severe anxiety, panic attacks, severe depression, insomnia, swelling of extremities, bloat/gassy, blurred vision, icy hands/feet, arrhythmia, shortness of breath, chest vibrations). It's been 1 year and 3 months since discontinuation. I am STILL experiencing off and on arrhythmia. I've had a thorough exam and testing with 30-day monitoring from 2 different cardiologists. My heart is very healthy, no blockages, no disease. Neither cardiologist can find any reason for the persistent arrhythmia, nor will they believe me when I tell them I think the Toprol caused this long-term persistent arrhythmia. I've also had extensive endocrinology testing and nothing is coming up as a reason for this arrhythmia. NOTE: I've never in my entire life had any heart arrhythmia or palpitations UNTIL I took Toprol, and now it's a regular occurrence. This cannot be a coincidence."

1 / 10
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  • Anonymous
  • March 27, 2008

For High Blood Pressure "I have been taking Toprol-XL for 10 years. I began with 50 mg per day, and I am now at 200 mg per day. Unlike another report posted here, I am sleeping better while taking the medication. The only two side effects I've experienced are shakiness and nervousness when I miss a dose by even a few hours, and vague aural hallucinations (hearing things) while on the verge of falling asleep. I've seen the hallucinations reported by other Toprol-XL users on other sites."

10 / 10
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  • Anonymous
  • January 2, 2010

For High Blood Pressure "I have not liked this medication at all. I was taking 25 mg of Hydrochlorothiazide, which worked great to reduce and maintain my blood pressure, but a side effect was frequent urination, and as a teacher, that was a slight nuisance. However, with generic Toprol, I have not gotten a decent night's sleep, and my blood pressure went higher (although I halved the 25 mg pill due to the side effects). I also feel anxious and unsettled."

2 / 10
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More FAQ

  • Sca...
  • Taken for 1 to 6 months
  • October 30, 2021

For High Blood Pressure "DON'T TAKE THIS POISON!!! I was on it only 2 months. Weaned off as directed after experiencing horrible side effects (fatigue, shortness of breath, bloating/gassy, weight gain, joint pain, limb swelling, facial swelling) and went through an absolute nightmare getting off of this drug. I had severe panic attacks, anxiety attacks, depression, insomnia, arrhythmia, vagus nerve dysfunction, and chest vibrations. It has been 8 months since I discontinued this awful drug, and the arrhythmia continues on a regular basis. I never had any palpitations or arrhythmias ever in my life until I took Toprol, and now it's a daily problem. I fully regret ever taking Toprol. It was nothing but bad from the very first pill....."

1 / 10
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  • Anonymous
  • September 9, 2010

For High Blood Pressure "Took it 2 times and it gave me chest pain, nervousness, and could not sleep. Stopped taking it."

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.